CN102688869A - On-line raw plasma bag cleaning and disinfecting control device - Google Patents

On-line raw plasma bag cleaning and disinfecting control device Download PDF

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Publication number
CN102688869A
CN102688869A CN2012101873913A CN201210187391A CN102688869A CN 102688869 A CN102688869 A CN 102688869A CN 2012101873913 A CN2012101873913 A CN 2012101873913A CN 201210187391 A CN201210187391 A CN 201210187391A CN 102688869 A CN102688869 A CN 102688869A
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China
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conveyer belt
alcohol
station
control device
plasma bag
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CN2012101873913A
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CN102688869B (en
Inventor
王苛义
张裴光
陈祥文
廖晓飞
陈志云
张东
李明坡
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Shandong institute of biological products
Shandong Taibang Biological Product Co Ltd
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Shandong institute of biological products
Shandong Taibang Biological Product Co Ltd
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Abstract

The invention discloses an on-line raw plasma bag cleaning and disinfecting control device. The device comprises a conveyer belt, the front section of the conveyer belt is horizontal, the middle section of the conveyer belt is sunken, and the rear section of the conveyer belt is inclined upwards; a circulating water flushing station and a first compressed air flushing station are sequentially arranged from front to back on the front section of the conveyer belt; the middle section of the conveyer belt is arranged in an alcohol tank; a fresh water flushing station and a second compressed air flushing station are sequentially arranged from front to back on the rear section of the conveyer belt; and the circulating water flushing station, the fresh water flushing station and/or the compressed air flushing stations are automatically controlled on line through a computer. Through the device, a series of continuous cleaning operations of automatic cleaning, disinfection and the like of a plasma bag are realized by automatic on-line control of the computer, human errors, pollution and cross pollution caused by open operation are avoided, and the labor intensity and the working time of operators are greatly reduced; and by designing circulating water and alcohol circulating devices, the consumption of alcohol and injection water is greatly reduced, and energy saving and consumption reducing benefits are remarkable.

Description

A kind of raw blood plasma bag cleaning and sterilizing On-line Control device
Technical field
The present invention relates in the blood product industry plasma bags is carried out the device of automatic cleanse and disinfect, be specifically related to a kind of raw blood plasma bag cleaning and sterilizing On-line Control device.
Background technology
The existing plasma bags cleanse and disinfect of domestic blood product industry can not the realization flow operation, generally in fermentation vat, soak dissolve slurry after, put into the alcohol pond again and carry out the plasma bags sterilizing operation, put into service sink then and carry out the plasma bags cleaning operation.All need manual work to wash plasma bags by rubbing with the hands in the operating process of above-mentioned sterilization and cleaning, labour intensity is big, and operating process is consuming time many, and has the risk of human error, pollution and cross pollution, and the waste of alcohol and water for cleaning is serious, is unfavorable for saving energy and reduce the cost.
Summary of the invention
Based on above-mentioned technical problem, the present invention provides a kind of raw blood plasma bag cleaning and sterilizing On-line Control device.
Its technical solution is:
A kind of raw blood plasma bag cleaning and sterilizing On-line Control device, it comprises conveyer belt, is respectively arranged with water flushing station, compressed air rinsing station and/or alcohol pond in the correspondent section of conveyer belt.
The leading portion level of said conveyer belt; The interlude depression; Back segment is tilted to; Before and after conveyer belt leading portion place, set gradually circulating water flushing station and compressed air rinsing first station, the conveyer belt interlude places the alcohol pond, before and after conveyer belt back segment place, sets gradually fresh water flushing station and compressed air rinsing second station.
Above-mentioned water flushing station and/or compressed air rinsing station all link to each other with computer, and carry out automatic online control through computer.
Above-mentioned circulating water flushing station comprises circulating water pipeline; Below the circulating water pipeline delivery port, be provided with transmission that is used for support belt and the casing of collecting recirculated water; Bottom at casing sets out the mouth of a river; Below delivery port, place a staving, the recirculated water of collecting in the staving is gone into circulating water pipeline after through water pump, filter.
Further, the alcohol pond connects the alcohol circulatory system, and the alcohol circulatory system comprises the alcohol basin; The alcohol basin connects input duct and reflux line; Input duct connects the inlet in alcohol pond, and reflux line connects the overfall in alcohol pond, and ethanol pump and filter are installed on input duct.
Further, this device also comprises alkali liquor circulating system, alkali liquor circulating system and circulating water flushing station common recycle waterpipe and the staving that it is coated with the alkali protection.
Said conveyer belt is made up of 9 pairs of sprocket wheels and is passed through motor-driven; Above-mentioned casing is welded by 304 stainless steels.
Useful technique effect of the present invention is:
(1) the present invention realizes melting a series of continuous clean operations such as automatic cleaning, sterilization of slurry process plasma bags through the computer automation On-line Control; Avoided human error, pollution and cross pollution open, interrupted, that manual operation causes, adapted to " GMP (revised edition in 2010) " and installations and facilities and technological procedure have been carried out the requirement of " confirming and checking ".Through experimental verification, use this apparatus processes plasma bags after company's cryoprecipitate (blood product intermediate products) pollution rate obviously descend, the cryoprecipitate qualification rate is promoted to 96.7% by 91.5%, is equivalent to year to practice thrift 18.2 tons of blood plasma.
(2) significantly reduced the consumption of alcohol and water for injection through design and installation cycling use of water and alcohol EGR, energy-saving and cost-reducing remarkable benefit.Wherein obvious with the alcohol saving, according to throwing 350 tons of calculating of slurry company's year, can save 93 tons of alcohol, practice thrift nearly 700,000 yuan of cost.
(3) control of the automatic online of this system can significantly reduce labor intensity of operating staff and man hour of labour, the production cycle of significantly shortened the plasma bags cleaning, sterilizing, melting slurry.
Description of drawings
Below in conjunction with the accompanying drawing and the specific embodiment the present invention is described further:
Fig. 1 is a kind of structural principle sketch map of raw blood plasma bag cleaning and sterilizing On-line Control device;
Fig. 2 is the side view of Fig. 1;
Fig. 3 is the structural representation of equipment box;
Fig. 4 is the structural representation of conveyer belt;
Fig. 5 is recirculated water and alkali lye spraying pipeline schematic diagram;
Fig. 6 is the structural representation of the alcohol circulatory system.
Among the figure: 1-workbench, 2-fermentation vat, 3-conveyer belt, 4-circulating water flushing station, 5-compressed air rinsing first station; 6-alcohol pond, 7-fresh water flushing station, 8-compressed air rinsing second station, 9-casing, 10-staving; 301-conveyer belt leading portion, 302-conveyer belt interlude, 303-conveyer belt back segment, 401-circulating water pipeline, 402-water pump; The 403-filter, 404-rotating wash bowl house steward, 405-remove the fermentation vat pipeline, 601-alcohol basin, 602-input duct; The 603-reflux line, 604-ethanol pump, 605-filter, 901-delivery port.
The specific embodiment
As shown in Figure 1, a kind of raw blood plasma bag cleaning and sterilizing On-line Control device, it comprises conveyer belt 3, is provided with fermentation vat 2 in the place ahead of conveyer belt 3, fermentation vat 2 is placed on the workbench 1.Conveyer belt 3 is made up of 9 pairs of sprocket wheels and through motor-driven, is encompassed Fig. 4 shape.Leading portion 301 levels of conveyer belt 3; Interlude 302 depressions; Back segment 303 is tilted to; Before and after conveyer belt leading portion 301 places, set gradually circulating water flushing station 4 and compressed air rinsing first station 5, conveyer belt interlude 302 places alcohol pond 6, before and after conveyer belt back segment 303 places, sets gradually fresh water flushing station 7 and compressed air rinsing second station 8.To and place on the conveyer belt 3 through the taking-up of the plasma bags after fermentation vat 2 melts slurry; Plasma bags is in the course of conveying of conveyer belt 3; Carry out the flushing first time through circulating water flushing station 4 earlier; And dry up through compressed air rinsing first station 5, get into the concentration that reduces alcohol in the alcohol pond in the alcohol pond 6 to prevent moisture residual on the plasma bags; Plasma bags is passed through the alcohol ponds with conveyer belt 3 then, and in the alcohol pond, carries out disinfection; Plasma bags after sterilization moves up with conveyer belt, carries out the second time through fresh water flushing station 7 again and cleans, and dry up through compressed air rinsing second station 8, promptly accomplishes the cleaning and sterilizing of plasma bags.
Circulating water flushing station 4 comprises circulating water pipeline 401, below circulating water pipeline 401 delivery ports, is provided with casing 9, and recirculated water and fresh water go in the casing 9 to collect to plasma bags flushing back current-sharing, and casing 9 also can be used for the transmission of support belt.Casing 9 is welded by 304 stainless steels, influences the quality that plasma bags is cleaned to prevent to get rusty.Set out the mouth of a river 901 in the bottom of casing 9; Below delivery port 901, place a staving 10; The recirculated water of collecting in the staving 10 gets into circulating water pipeline 401 after through water pump 402, filter 403 once more, and under the pressure of water pump 402 strong flushing plasma bags surface.Recirculated water in the staving 10 also can be delivered to fermentation vat 2 through removing fermentation vat pipeline 405, satisfies the water demand of plasma bags surface clean in the fermentation vat.Alcohol pond 6 connects the alcohol circulatory system; As shown in Figure 6; The alcohol circulatory system comprises alcohol basin 601, and alcohol basin 601 connects input duct 602 and reflux line 603, and input duct 602 connects the inlet in alcohol pond; Reflux line 603 connects the overfall in alcohol pond, and ethanol pump 604 and filter 605 are installed on input duct.Alcohol in the alcohol basin 601 gets in the alcohol pond 6 through ethanol pump 604, filter 605; Plasma bags is sterilized through the alcohol pond under the conveying of conveyer belt; Alcohol overflows in the alcohol basin 601 through reflux line 603 in the conveying of ethanol pump, recycles.In the production use, can carry out the detection of alcohol concentration, be used for the alcohol concentration of plasma bags sterilization with control through the sample tap sampling.
After work is accomplished, need equipment is coated with the alkali protection, spraying alkali lye adopts alkali liquor circulating system; Alkali liquor circulating system and circulating water flushing station common recycle waterpipe and staving etc.; Promptly need be coated with alkali when protection, only need to change the recirculated water in the staving into alkali lye and circulate and get final product, can open the path of alkaline stream in addition to rotating wash bowl house steward 404 to equipment; Wherein rotating wash bowl house steward 404 connects 3 rotating wash bowls, makes alkali lye be coated with the alkali operation with the form of spray to equipment.Can realize being coated with alkali operation no dead angle comprehensively through aforesaid operations, sterilization effect is solid.
Said apparatus also comprises electrical apparatus control system; Conveyer belt, circulating water flushing station, compressed air rinsing first station, the alcohol pond circulatory system, fresh water flushing station and compressed air rinsing second station etc. all link to each other with electrical apparatus control system; Electrical apparatus control system control is used to drive the running of the motor that conveyer belt rotates; And on control circulating water flushing station, compressed air rinsing first station, fresh water flushing station and compressed air rinsing second station valve unlatching, close and the running of water pump, control simultaneously valve in the alcohol circulatory system unlatching, close and the running of ethanol pump.Electrical apparatus control system connects computer, and carries out automatic online control through computer.
Certainly; Also can set up a plurality of circulating water flushing stations, fresh water flushing station and compressed air rinsing station, like this can according to the quantity of plasma bags that conveyer belt is carried what or other situation selection appropriate section or whole circulating water flushing station, fresh water wash station and compressed air rinsing station unlatching, close.
Need to prove that under the instruction of this specification, any equivalents that those skilled in the art have done, or obvious variant all should be within protection scope of the present invention.

Claims (7)

1. raw blood plasma bag cleaning and sterilizing On-line Control device, be characterised in that: it comprises conveyer belt, is respectively arranged with water flushing station, compressed air rinsing station and/or alcohol pond in the correspondent section of conveyer belt.
2. a kind of raw blood plasma bag cleaning and sterilizing On-line Control device according to claim 1; It is characterized in that: the leading portion level of conveyer belt; The interlude depression, back segment is tilted to, and before and after conveyer belt leading portion place, sets gradually circulating water flushing station and compressed air rinsing first station; The conveyer belt interlude places the alcohol pond, before and after conveyer belt back segment place, sets gradually fresh water flushing station and compressed air rinsing second station.
3. a kind of raw blood plasma bag cleaning and sterilizing On-line Control device according to claim 1 is characterized in that: said water flushing station and/or compressed air rinsing station all carry out automatic online control through computer.
4. a kind of raw blood plasma bag cleaning and sterilizing On-line Control device according to claim 2; It is characterized in that: said circulating water flushing station comprises circulating water pipeline; Below the circulating water pipeline delivery port, be provided with transmission that is used for support belt and the casing of collecting recirculated water; Bottom at casing sets out the mouth of a river, below delivery port, places a staving, and the recirculated water of collecting in the staving is gone into circulating water pipeline after through water pump, filter.
5. a kind of raw blood plasma bag cleaning and sterilizing On-line Control device according to claim 2; It is characterized in that: the alcohol pond connects the alcohol circulatory system; The alcohol circulatory system comprises the alcohol basin, and the alcohol basin connects input duct and reflux line, and input duct connects the inlet in alcohol pond; Reflux line connects the overfall in alcohol pond, and ethanol pump and filter are installed on input duct.
6. a kind of raw blood plasma bag cleaning and sterilizing On-line Control device according to claim 4; It is characterized in that: this device also comprises alkali liquor circulating system, alkali liquor circulating system and circulating water flushing station common recycle waterpipe and the staving that it is coated with the alkali protection.
7. a kind of raw blood plasma bag cleaning and sterilizing On-line Control device according to claim 4 is characterized in that: said conveyer belt is made up of 9 pairs of sprocket wheels and is passed through motor-driven; Said casing is welded by 304 stainless steels.
CN201210187391.3A 2012-06-08 2012-06-08 On-line raw plasma bag cleaning and disinfecting control device Active CN102688869B (en)

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103056138A (en) * 2013-01-17 2013-04-24 衡阳鑫山机械设备制造有限公司 Washing and sterilizing machine of automatic blood plasma bag washing, sterilizing and breaking equipment
CN103071655A (en) * 2013-01-16 2013-05-01 衡阳鑫山机械设备制造有限公司 Combined equipment for automatically cleaning, disinfecting and breaking blood plasma bag
CN105817445A (en) * 2016-05-27 2016-08-03 四川南格尔生物科技有限公司 Automatic cleaning system and method for double faces of filling bag
CN105819036A (en) * 2016-05-27 2016-08-03 四川南格尔生物科技有限公司 Automatic bag washing and blow-drying system and method
CN109172846A (en) * 2018-10-23 2019-01-11 广州达意隆包装机械股份有限公司 A kind of decontamination system and disinfection control
CN113731986A (en) * 2021-08-31 2021-12-03 宜兴市昌华过滤器材有限公司 Multifunctional automatic cleaning equipment for plasma bags
CN115569947A (en) * 2021-07-05 2023-01-06 四川远大蜀阳药业有限责任公司 Bag cleaning apparatus, bag cleaning method, and bag processing system

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US6268910B1 (en) * 1997-03-03 2001-07-31 Cme Telemetrix Inc. Method and apparatus for screening plasma for interferents in plasma from donor blood bags
CN2497892Y (en) * 2001-08-25 2002-07-03 湖南省郴州市山河电子设备有限公司 Ultrasonic bottle washer
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CN201807570U (en) * 2010-10-13 2011-04-27 湖南东港锑品有限公司 Antimony powder bag cleaning device
CN202006188U (en) * 2011-02-18 2011-10-12 刘建军 Ultrasonic cleaning device for flux-cored wire steel strip
CN202010673U (en) * 2010-12-31 2011-10-19 山西华能食品包装机械有限公司 Ultrasonic box washer
CN202061845U (en) * 2011-04-14 2011-12-07 常州工程职业技术学院 Device for recycling medical PP (polypropylene) saline bag

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5344561A (en) * 1989-05-09 1994-09-06 Pall Corporation Device for depletion of the leucocyte content of blood and blood components
US6268910B1 (en) * 1997-03-03 2001-07-31 Cme Telemetrix Inc. Method and apparatus for screening plasma for interferents in plasma from donor blood bags
CN2497892Y (en) * 2001-08-25 2002-07-03 湖南省郴州市山河电子设备有限公司 Ultrasonic bottle washer
CN201565431U (en) * 2009-04-23 2010-09-01 上海旺欣豆制品设备有限公司 Plastic bag cleaning machine
CN201410488Y (en) * 2009-06-12 2010-02-24 河南新天地药业股份有限公司 Medicine bottle cleaning and disinfecting groove
CN201807570U (en) * 2010-10-13 2011-04-27 湖南东港锑品有限公司 Antimony powder bag cleaning device
CN202010673U (en) * 2010-12-31 2011-10-19 山西华能食品包装机械有限公司 Ultrasonic box washer
CN202006188U (en) * 2011-02-18 2011-10-12 刘建军 Ultrasonic cleaning device for flux-cored wire steel strip
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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103071655A (en) * 2013-01-16 2013-05-01 衡阳鑫山机械设备制造有限公司 Combined equipment for automatically cleaning, disinfecting and breaking blood plasma bag
CN103056138A (en) * 2013-01-17 2013-04-24 衡阳鑫山机械设备制造有限公司 Washing and sterilizing machine of automatic blood plasma bag washing, sterilizing and breaking equipment
CN105817445A (en) * 2016-05-27 2016-08-03 四川南格尔生物科技有限公司 Automatic cleaning system and method for double faces of filling bag
CN105819036A (en) * 2016-05-27 2016-08-03 四川南格尔生物科技有限公司 Automatic bag washing and blow-drying system and method
CN109172846A (en) * 2018-10-23 2019-01-11 广州达意隆包装机械股份有限公司 A kind of decontamination system and disinfection control
CN109172846B (en) * 2018-10-23 2024-03-19 广州达意隆包装机械股份有限公司 Disinfection system and disinfection control method
CN115569947A (en) * 2021-07-05 2023-01-06 四川远大蜀阳药业有限责任公司 Bag cleaning apparatus, bag cleaning method, and bag processing system
CN113731986A (en) * 2021-08-31 2021-12-03 宜兴市昌华过滤器材有限公司 Multifunctional automatic cleaning equipment for plasma bags
CN113731986B (en) * 2021-08-31 2023-08-29 宜兴市昌华过滤器材有限公司 Multifunctional plasma bag automatic cleaning equipment

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Address after: 271000 5666 Longquan Road, hi tech Zone, Tai'an, Shandong

Patentee after: SHANDONG TAIBANG BIOLOGICAL PRODUCTS Co.,Ltd.

Patentee after: SHANDONG INSTITUTE OF BIOLOGICAL PRODUCTS

Address before: 271000 No. 14 East Tiger Hill Road, Shandong, Tai'an

Patentee before: SHANDONG TAIBANG BIOLOGICAL PRODUCTS Co.,Ltd.

Patentee before: SHANDONG INSTITUTE OF BIOLOGICAL PRODUCTS