CN102688467A - 一种治疗冻疮的中药制剂 - Google Patents
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Abstract
一种治疗冻疮的中药制剂，该中药制剂是由马鞭草，紫草，桂枝，炮姜，虎杖，五灵酯，桃仁，川芎，郁金制成。临床可用于治疗冻疮。
Description
技术领域
本发明属于中药技术领域，尤其是涉及一种治疗冻疮的中药制剂。
背景技术
冻疮是由于较长时间的寒冷和潮湿刺激引起的阻性充血性红斑，与患者的个体素质、周围血循环不良有关。多见于学生、青年女性或久坐不动、外出作业者。当手指、手背、脚趾、足跟、鼻尖、耳轮、耳垂等处受凉后，局部发紫红色水肿红斑，边界不清，触之较冷硬，压之易褪色，去压后红色恢复较慢，呈局部血流积滞。常对称分布，有痒、胀和烧灼感，于受热后或天气转暖时明显。重者破溃，春暖自愈，病程较慢，来年冬天易复发。西药的治疗效果并不好，发明人经过多年的临床实践发现，中药对于冻疮的治疗效果很好。
发明内容
本发明的目的在于提供一种治疗效果好、有效率高、对人体无毒副作用的治疗冻疮的中药制剂。
本发明的目的是这样实现的，根据中医药理论，利用中药独特的药性，采用马鞭草，紫草，桂枝，炮姜，虎杖，五灵酯，桃仁，川芎，郁金，按照一定的配伍要求，经过加工制成。
制备本发明中药制剂由下述原料药制成：马鞭草230-40份，紫草30-40份，桂枝30-40份，炮姜30-40份，虎杖20-40份，五灵酯20-40份，桃仁20-40份，川芎20-40份，郁金10-20份。
本发明中药制剂原料药的最佳重量份为：马鞭草35份，紫草35份，桂枝35份，炮姜35份，虎杖30份，五灵酯30份，桃仁30份，川芎30份，郁金15份。
本发明中药的药理作用如下：
马鞭草：苦、辛、微寒。归肝、脾经。清热解毒，活血通经，利水消肿，截虐。主治感冒发热，咽喉肿痛，牙龈肿痛，黄疸，痢疾，血瘀经闭，痛经，癥瘕，水肿，小便不利，疟疾，痈疮肿毒，跌打损伤等。
紫草：苦、寒。归心、肝经。凉血、活血、透疹、消毒。主治斑疹，麻疹，吐血，衄血，尿血，紫癜，黄疸，痈疽，烫伤等。
桂枝：辛、甘、温，归心、肺、膀胱经。发汗解肌，温通经脉，助阳化气。用于风寒感冒，寒凝血滞，痰饮、蓄水证。
炮姜：苦、辛、温。归脾、胃、肝经。温中止泻，温中止血。主治虚寒性脘腹疼痛，呕吐，泻痢，吐血，便血，崩漏等。
虎杖：苦、寒。归肝、胆、肺经。利胆退黄，清热解毒，活血祛瘀，祛痰止咳。用于湿热黄疸，淋浊带下，痈肿疮毒，毒蛇咬伤，肺热咳嗽等。
五灵脂：苦、咸、甘，温。归肝经。活血止痛，化瘀止血。用于瘀血阻滞诸证。
桃仁：苦、甘、平。归心、肝、大肠经。活血化瘀，润肠通便。用于多种瘀血证，肠燥便秘，肺痈，肠痈。
川芎：辛、温，归肝、胆、心经。活血行气，祛风止痛。用于血瘀气滞、风湿痹痛。
郁金：苦、辛、寒，归肝、胆、心经。活血行气止痛，解郁清心，利胆退黄，凉血。用于热病神昏、癫痫痰闭之证。
冻疮属中医“痹证”，病因病机多为局部感受寒湿，经脉受损，风寒湿邪乘虚侵入，使局部气血运行不畅，经脉痹阻，气滞血瘀，而致肿痛经久不解。治当清热解毒，活血化瘀。本发明中马鞭草、紫草、虎杖、五灵脂、桃仁、川芎、郁金清热解毒、活血化瘀，桂枝、炮姜温经散寒，诸药共用，达到治疗冻疮的目的。
本发明中药制剂于2008年至2010年临床观察冻疮45例患者，临床报告如下：
1、一般资料
45例患者中，年龄最小8岁，最大69岁，病程多在1个月到5年，平均年龄30.6岁。
2、诊断标准
参考国家中医药管理局《中医病症诊断疗效标准》。
(1)轻证：初起受冻部位皮肤先呈苍白，继则红肿，或有硬结，斑块，边缘红，中央青紫，冷痛，或感麻木，暖热时自觉灼热，瘙痒，胀痛；
(2)重证：有大小不等的水疱或肿块，皮肤呈灰白或暗红，或转紫色，疼痛剧烈，或局部感觉消失。水疱破后出现糜烂或溃疡，甚则肌肉筋骨坏死。
3、治疗方法
3.1处方：马鞭草35g，紫草35g，桂枝35g，炮姜35g，虎杖30g，五灵脂30g，桃仁30g，川芎30g，郁金15g。
3.2制备方法：上述药物粉碎后加入到5倍量95％乙醇中浸泡15天，滤过即得。
3.3使用方法：用时将局部清洗干净，用药棉蘸取药液，每天3-5次涂抹患处，5天为1个疗程。
4、治疗结果：
4.1参考国家中医药管理局《中医病症诊断疗效标准》。
痊愈：全身症状消失，红肿消退，麻木、痒痛消失，创面愈合；
好转：全身症状基本消失，麻木、痒痛均明显减轻，创面愈合；
无效：全身及局部症状无改善。
4.2结果：45例患者中，痊愈39例(86.7％)，好转6例(13.3％)，总有效率为100％，轻证患者一般1个疗程即可痊愈，重证患者一般3-4个疗程即可痊愈。
5、典型病例
5.1刘某，女，10岁，学生，冬天出现双手、足、耳、鼻及面部冻疮，有硬结，斑块，使用本发明中药制剂，1个疗程后痊愈，来年随访未复发。
5.2孙某，男，32岁，工人，已有4年病史，每逢冬天发作，双手指背红肿、瘙痒难忍，伴局部刺痛，有大小不等紫色暗疮，尚未溃烂。使用本发明中药制剂，3个疗程后，肿胀消失、奇痒停止，痊愈。来年随访未复发。
具体实施方式
下面结合实施例对本发明作进一步的说明，下述该实施例仅用于说明本发明而对本发明没有限制。
实施例1，一种治疗冻疮的中药制剂，它是由下述原料药制成：马鞭草30g，紫草30g，桂枝30g，炮姜30g，虎杖20g，五灵脂20g，桃仁20g，川芎20g，郁金10g。
实施例2，一种治疗冻疮的中药制剂，它是由下述原料药制成：马鞭草35g，紫草35g，桂枝35g，炮姜35g，虎杖30g，五灵脂30g，桃仁30g，川芎30g，郁金15g。
实施例3，一种治疗冻疮的中药制剂，它是由下述原料药制成：马鞭草40g，紫草40g，桂枝40g，炮姜40g，虎杖40g，五灵脂40g，桃仁40g，川芎40g，郁金20g。
Claims (2)
1.一种治疗冻疮的中药制剂，其特征在于它是由下述原料药制成：
马鞭草30-40份 紫草30-40份 桂枝30-40份 炮姜30-40份 虎杖20-40份
五灵酯20-40份 桃仁20-40份 川芎20-40份 郁金10-20份。
2.根据权利要求1所述的中药制剂，其特征在于它是由下述原料药制成：
马鞭草35份 紫草35份 桂枝35份 炮姜35份 虎杖30份
五灵酯30份 桃仁30份 川芎30份 郁金15份。
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| CN103263544A (zh) * | 2013-04-22 | 2013-08-28 | 缪友道 | 一种用于冻疮的中药 |
| CN104984313A (zh) * | 2015-08-11 | 2015-10-21 | 马千里 | 一种治疗冻疮的中药药酒 |
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| CN105796469A (zh) * | 2016-06-08 | 2016-07-27 | 马殿伟 | 一种含有五灵脂的用于防冻防裂化妆品的中药组合物 |
| CN106943527A (zh) * | 2017-04-14 | 2017-07-14 | 吴世贵 | 一种治疗冻疮的中药制剂 |
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| CN103263544A (zh) * | 2013-04-22 | 2013-08-28 | 缪友道 | 一种用于冻疮的中药 |
| CN104984313A (zh) * | 2015-08-11 | 2015-10-21 | 马千里 | 一种治疗冻疮的中药药酒 |
| CN104984313B (zh) * | 2015-08-11 | 2018-06-05 | 马千里 | 一种治疗冻疮的中药药酒 |
| CN105148250A (zh) * | 2015-10-30 | 2015-12-16 | 汪盈盈 | 一种治疗冻疮的中药药膏 |
| CN105796469A (zh) * | 2016-06-08 | 2016-07-27 | 马殿伟 | 一种含有五灵脂的用于防冻防裂化妆品的中药组合物 |
| CN106943527A (zh) * | 2017-04-14 | 2017-07-14 | 吴世贵 | 一种治疗冻疮的中药制剂 |
| CN108210848A (zh) * | 2018-04-04 | 2018-06-29 | 常州五荣化工有限公司 | 一种无痕冻疮膏的制备方法 |
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