CN102688360A - Externally-applied skin medicine for treating burn and scald - Google Patents
Externally-applied skin medicine for treating burn and scald Download PDFInfo
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Abstract
The invention relates to an externally-applied skin medicine, in particular relates to an externally-applied skin medicine for treating burn and scald and can be used for solving the problems of the existing treatment methods for burn and scald. The medicine is especially applicable to treating first-degree, second-degree and third-degree burn and scald. The medicine comprises the following raw materials in parts by weight: 20-30 parts of rhubarb, 10-20 parts of angelica sinensis, 10-25 parts of root of Sinkiang arnebia, 10-30 parts of fruit of cape jasmine, 10-30 parts of honeysuckle flower, 15-20 parts of radix sanguisorbae, 10-20 parts of rehmannia root, 10-20 parts of red peony root, 15-25 parts of ligusticum chuanxiong hort, 5-20 parts of calcined gypsum, 5-20 parts of pseudo-ginseng, 5-20 parts of dragon blood and 5-15 parts of borneol. The externally-applied skin medicine has reasonable and strict ingredient match and not only conforms to traditional Chinese medicine theory, but also reflects the achievement of modern traditional Chinese medicine pharmacological study. According to the reliable curative effect of countless patients during 6 ancestor generations, the medicine has the effects of clearing away heat and toxic materials, astringing pains, removing necrotic tissue and promoting tissue regeneration and resisting infection.
Description
Technical field
The present invention relates to a kind of external preparation for skin medicine, specifically is a kind of external preparation for skin medicine of treating burn and scald.
Background technology
Burn and scald is that a kind of the larger area burn and scald causes the damage of deep skin tissue by the caused traumatic disease of heating power, chemistry, material electric current and radioactivity, causes each system of body tangible functional metabolism and metamorphosis to occur; Serious burn and scald causes the extensive damage of skin complete property, and the basic functions such as the natural cover for defense, water conservation, regulate body temperature, immunity, drainage etc. are disequilibrium all, and district's set point raises in the body temperature; Metabolic alterations, inflammatory reaction occurs in succession, a series of variation of each system of body, reaction; Even infect; If the improper wound surface that causes of Local treatment can't heal, the treatment difficulty is big, brings lifelong misery to the patient.
Two kinds of Therapeutic Method of existing burn and scald: the one, the silver sulfadiazine suspension is coated with outward or cooperates the roasting and hot hair dryer of lamp to dry up; The 2nd, open wound is carried out tanning calcination art; Above-mentioned two kinds of Therapeutic Method all are to be primary goal with kill bacteria, control infection; But make the damage of wound surface increase the weight of, may cause the remaining appendages of skin to lose regenerated chance; In addition, adopt the excision of tendency towards compromise, the Therapeutic Method of skin-grafting can involve healthy subcutaneous tissue, have simultaneously that the wound surface dressing change frequency is many, operation wound is big, pain is hemorrhage, the course of disease is long, medical expense is high, leave over defective such as cicatrix after healing.
Summary of the invention
The present invention provides a kind of external preparation for skin medicine of treating burn and scald for the problem that the Therapeutic Method that solves existing burn and scald exists, and is specially adapted to treat I, II, III degree burn and scald.
The present invention is achieved by the following technical solutions: a kind of external preparation for skin medicine of treating burn and scald is to be made by the raw material of following parts by weight, 20～30 parts of rheum officinales, 10～20 parts of Radix Angelicae Sinensis; 10～25 parts of Asian puccoons, 10～30 parts of cape jasmines, 10～30 parts of honeysuckles, 15～20 parts of garden burnets; 10～20 parts in the dried rhizome of rehmannia, 10～20 parts of RADIX PAEONIAE RUBRAs, 15～25 parts of rhizome of chuanxiongs, 5～20 parts of calcined gypsums; 5～20 parts of pseudo-ginseng, 5～20 parts of dragon's blood, 5～15 parts of borneols.
The invention uses rhubarb, angelica, comfrey, gardenia, honeysuckle, Burnet, habitat, TPG drugs, Chuan Qiong, calcined gypsum, Panax, blood, borneol group parties, including rhubarb, comfrey, honeysuckle, Burnet has cooling, anti-inflammatory, detoxifying effect of heat cured, gardenia, habitat, TPG drugs, Sichuan dome, there are expelling wind and cold, blood circulation, anti-inflammatory effect, calcined gypsum, Panax, blood, borneol with blood pain, OK silt, Qufushengji effect.
Modern pharmacology research also confirms, rheum officinale has hemostasis, antibiotic, anti-inflammatory, analgesic, immunological regulation, effect such as anti-ageing, anti-oxidant; Radix Angelicae Sinensis has anti-anoxic, regulates body's immunity, anticancer, improve looks, enrich blood invigorate blood circulation, effect such as antibacterial, anti-inflammatory; That Asian puccoon has is antibacterial, anti-inflammatory, effect such as analgesic, and there is facilitation in the ointment local application of Radix Arnebiae extract or its pigment composition preparation simultaneously to the propagation of granulation tissue, can obviously quicken wound healing; Cape jasmine is except having hemostasis, suppressing the dermatophyte effect, and its extract has the effect of certain anti-inflammatory and treatment soft tissue injury, and the ointment local application of making, and can quicken the healing of soft tissue; Honeysuckle has effects such as resisting pathogenic microbes, anti-inflammatory, analgesic, booster immunization function; Garden burnet has convergence, antibiotic, anti-inflammatory, hemostasis, promotes effects such as wound healing; Effects such as that the dried rhizome of rehmannia has is analgesic, pain relieving, hemostasis; RADIX PAEONIAE RUBRA has analgesia, calmness, anti-inflammatory, antiulcer, effect such as antibiotic, analgesic; Rhizome of chuanxiong can suppress multiple bacillus, has effects such as pain relieving; Calcined gypsum has hemostasis, myogenic, holds back wound, hemostasis, effect such as antipruritic; Pseudo-ginseng can promote the synthetic of protein, ribonucleic acid, DNA, promotes blood cell metabolism, the balance adjustment blood cell, and the enhancing body immunologic function has effects such as hemostasis, promoting blood circulation and removing blood stasis, anti-inflammatory; Effects such as that dragon's blood has is antimycotic, hemostasis, pain relieving; Borneol has effects such as swelling and pain relieving, anti-inflammatory.
Raw material of Chinese medicine of the present invention can be processed any clinical external preparation for skin pharmaceutically dosage form, for example spray, tincture, ointment, plaster, liniment, powder, oil preparation, Emulsion, aerosol of being applicable to.
The method for preparing of described spray is: the above-mentioned raw materials medical material according to standards of pharmacopoeia and the decocte with water of Chinese medicine processing standard, is promptly got spray.The method for preparing of described tincture is: the above-mentioned raw materials medical material is immersed ethanol according to standards of pharmacopoeia, filter and obtain leachate, promptly get tincture.The method for preparing of described oil preparation is: the above-mentioned raw materials medical material is worn into fine powder according to standards of pharmacopoeia, join in the Oleum sesami, promptly get oil preparation.
Introduce a kind of preparation method who prepares external preparation for skin medicine ointment of the present invention below: (1) get rheum officinale, Radix Angelicae Sinensis, Asian puccoon, cape jasmine, honeysuckle, garden burnet, the dried rhizome of rehmannia, RADIX PAEONIAE RUBRA, rhizome of chuanxiong stripping and slicing, immerse 6～10h in 300～800 parts the sesame oil; (2) immersion is had the sesame oil of medicinal material boil to medicinal material and be coke yellow, oil temperature (sesame oil boil temperature) is 90～100 ℃, and the elimination dregs of a decoction obtain first medicine oil; (3) first medicine oil are cooled to 40～50 ℃, add 20～50 parts beeswax, are stirred to beeswax and melt fully, obtain second medicine oil; (4) second medicine oil are cooled to 15～25 ℃, add borneol and be stirred to borneol to melt fully, and elimination impurity obtains the 3rd medicine oil; (5) get calcined gypsum, pseudo-ginseng, the broken abrasive dust of dragon's blood, require powder particle to pass through 100 mesh sieves, radiation sterilization; Add the powder that step (5) obtains in (6) the 3rd medicine oil, stir, obtain the ointment of said externally applied drug.Described Oleum sesami, Cera Flava have the effect of convergence dampness, and the ointment that makes of above-mentioned method for preparing, can give full play to drug effect, use better efficacy, and analgesic effect is clear and definite, in the time of control infection, can promote the healing of wound surface rapidly.During concrete the use, can directly be applied to wound surface, need not wrapping, easy to use.
External preparation for skin medicine prescription compatibility of the present invention is reasonable, rigorous, has both met traditional Chinese medicine theory, has embodied modern Chinese medicine pharmacological research achievement again; Also be that the certain curative effect through countless patients is proved on the basis in 6 generations handed down from one's ancestors, have the effect of pain, removing the necrotic tissue and promoting granulation, infection of heat-clearing and toxic substances removing, convergence, remedied the defective that existing burn and scald Therapeutic Method exists; Evident in efficacy aspect the various burn and scald of treatment; Especially for large tracts of land deep burn skin ulceration excellent curative is arranged, control infection the time, promote the healing of wound surface rapidly apace; Analgesic effect is obvious; More the back wound surface does not have cicatrix, and that skin function recovers is good, safe and reliable, have no side effect.
Experiment: the observation of curative effect of the external preparation for skin medicine of treatment burn and scald of the present invention
The present invention selects to meet patient's 800 examples (wherein boiled water is scalded 90 examples, petrol burn 122 examples, edible oil and scalded 136 examples, other burn and scald 452 examples) of burn and scald; The ointment that gives external preparation for skin medicine of the present invention all be applied in wound surface; Cure rate reaches 100%, and effective percentage reaches 100%.
I degree burn and scald patient 126 examples, wound healing after medication 3-5 days; Light degree burn and scald patient 194 examples, a medication 5-7 days wound surface promptly heals; Dark II degree burn and scald patient 160 examples treat that wound surface promptly heals after 10-15 days; III degree burn and scald patient 54 examples, the 30-40 days left and right sides wound surface of patient's medication of not making skin graft promptly heal.There are 60 examples to use the patients that still can't cure in Therapeutic Method 1-3 month of silver sulfadiazine in the 800 above-mentioned in addition examples, even also have the patient of skin-grafting failure, all cure after all being to use Ointment in Treatment 20-30 days of external preparation for skin medicine of the present invention.Confirm: external preparation for skin medication of the present invention is imitated significantly.
Model case
1. Liu, man, 48 years old, peasant.In May, 2000 bursting of boilers in construction causes face, chest, abdominal part, extremity skin burn, and burn surface area is 50%; All do not heal in the various big hospital treatment; The surface has pus crusts to adhere to, and under the crust purulent secretion is arranged, and involves residual wound; And wound surface is with infection, and major part is dark II degree after diagnosing; Smear once the ointment of external preparation for skin medicine of the present invention back every day, after 5 days, be clearly better, the wound surface clean, granulation is fresh, and purulent secretion disappears, and after 20 days, wound healing was followed up a case by regular visits to after half a year, did not see scar hyperplasia, and the extremity function is accessible.
2. Zhang, woman, 38 years old; Scalded by boiled water accidentally when cooking, area reaches 20% of whole body, does not all heal in the various big hospital treatment; After use the normal saline flushing wound surface once a day, then with the ointment of external preparation for skin medicine of the present invention all be applied in wound surface, wound surface all heals after 15 days; Follow up a case by regular visits to half a year, no scar hyperplasia, skin function recover good.
3. Zhao, the man, 15 years old, the student was scalded both feet by boiled water accidentally; Bubble, decortication, pain can't be walked unbearably; Go each big out-patient treatment commentaries on classics of all not getting better, after once a day external preparation for skin medicine of the present invention evenly is applied in wound surface, recovery from illness after 10 days, both feet are not seen tangible cicatrix.
The specific embodiment
Embodiment 1: every part is 1 gram
A kind of external preparation for skin medicine of treating burn and scald is to be made by the raw material of following parts by weight, rheum officinale 20 grams, Radix Angelicae Sinensis 12 grams, Asian puccoon 18 grams; Cape jasmine 25 grams, honeysuckle 28 grams, garden burnet 20 grams, the dried rhizome of rehmannia 18 grams, RADIX PAEONIAE RUBRA 16 grams; Rhizome of chuanxiong 19 grams, calcined gypsum 8 grams, pseudo-ginseng 5 grams, dragon's blood 8 grams, borneol 10 grams; Above-mentioned all medicines all according to the processing of standards of pharmacopoeia standard, can be made into various external preparation for skin pharmaceutically dosage forms, like spray.
Embodiment 2: every part is 1 jin
A kind of external preparation for skin medicine of treating burn and scald, its preparation method is: (1) get 22 jin of rheum officinales, 14 jin of Radix Angelicae Sinensis, 20 jin of Asian puccoons, 20 jin of cape jasmines, 15 jin of honeysuckles, 15 jin of garden burnets, 12 jin of dried rhizome of rehmannia, 14 jin of RADIX PAEONIAE RUBRAs, 20 jin of rhizome of chuanxiong strippings and slicings, immerse 10h in 650 jin the sesame oil; (2) immersion is had the sesame oil of medicinal material boil to medicinal material and be coke yellow, oily temperature is 97 ℃, and the elimination dregs of a decoction obtain first medicine oil; (3) first medicine oil are cooled to 45 ℃, add 28 parts beeswax, are stirred to beeswax and melt fully, obtain second medicine oil; (4) second medicine oil are cooled to 15 ℃, add 8 jin of borneols and be stirred to borneol to melt fully, and elimination impurity obtains the 3rd medicine oil; (5) get 15 jin of calcined gypsums, 13 jin of pseudo-ginseng, 10 jin of broken abrasive dusts of dragon's blood, require powder particle to pass through 100 mesh sieves, radiation sterilization; Add the powder that step (5) obtains in (6) the 3rd medicine oil, stir, obtain the ointment of said externally applied drug.
Embodiment 3: every part is 1 kilogram
A kind of external preparation for skin medicine of treating burn and scald, its preparation method is: (1) get 26 kilograms of rheum officinales, 20 kilograms of Radix Angelicae Sinensis, 10 kilograms of Asian puccoons, 15 kilograms of cape jasmines, 20 kilograms of honeysuckles, 18 kilograms of garden burnets, 14 kilograms of dried rhizome of rehmannia, 12 kilograms of RADIX PAEONIAE RUBRAs, 17 kilograms of rhizome of chuanxiong strippings and slicings, immerse 8h in 450 kilograms the sesame oil; (2) immersion is had the sesame oil of medicinal material boil to medicinal material and be coke yellow, oily temperature is 93 ℃, and the elimination dregs of a decoction obtain first medicine oil; (3) first medicine oil are cooled to 40 ℃, add 20 kilograms beeswax, are stirred to beeswax and melt fully, obtain second medicine oil; (4) second medicine oil are cooled to 25 ℃, add borneol and be stirred to 13 kilograms of borneols to melt fully, and elimination impurity obtains the 3rd medicine oil; (5) get 13 kilograms of calcined gypsums, 20 kilograms of pseudo-ginseng, 15 kilograms of broken abrasive dusts of dragon's blood, require powder particle to pass through 100 mesh sieves, radiation sterilization; Add the powder that step (5) obtains in (6) the 3rd medicine oil, stir, obtain the ointment of said externally applied drug.
Embodiment 4: every part is 1 jin
A kind of external preparation for skin medicine of treating burn and scald, its preparation method is: (1) get 30 jin of rheum officinales, 18 jin of Radix Angelicae Sinensis, 25 jin of Asian puccoons, 10 jin of cape jasmines, 30 jin of honeysuckles, 17 jin of garden burnets, 16 jin of dried rhizome of rehmannia, 20 jin of RADIX PAEONIAE RUBRAs, 23 jin of rhizome of chuanxiong strippings and slicings, immerse 7h in 500 jin the sesame oil; (2) immersion is had the sesame oil of medicinal material boil to medicinal material and be coke yellow, oily temperature is 100 ℃, and the elimination dregs of a decoction obtain first medicine oil; (3) first medicine oil are cooled to 43 ℃, add 20 parts beeswax, are stirred to beeswax and melt fully, obtain second medicine oil; (4) second medicine oil are cooled to 25 ℃, add 12 jin of borneols and be stirred to borneol to melt fully, and elimination impurity obtains the 3rd medicine oil; (5) get 10 jin of calcined gypsums, 8 jin of pseudo-ginseng, 5 jin of broken abrasive dusts of dragon's blood, require powder particle to pass through 100 mesh sieves, radiation sterilization; Add the powder that step (5) obtains in (6) the 3rd medicine oil, stir, obtain the ointment of said externally applied drug.
Embodiment 5: every part is 1 kilogram
A kind of external preparation for skin medicine of treating burn and scald, its preparation method is: (1) get 24 kilograms of rheum officinales, 16 kilograms of Radix Angelicae Sinensis, 13 kilograms of Asian puccoons, 30 kilograms of cape jasmines, 10 kilograms of honeysuckles, 19 kilograms of garden burnets, 10 kilograms of dried rhizome of rehmannia, 18 kilograms of RADIX PAEONIAE RUBRAs, 15 kilograms of rhizome of chuanxiong strippings and slicings, immerse 6h in 800 kilograms the sesame oil; (2) immersion is had the sesame oil of medicinal material boil to medicinal material and be coke yellow, oily temperature is 95 ℃, and the elimination dregs of a decoction obtain first medicine oil; (3) first medicine oil are cooled to 47 ℃, add 50 kilograms beeswax, are stirred to beeswax and melt fully, obtain second medicine oil; (4) second medicine oil are cooled to 18 ℃, add 5 parts of borneols and be stirred to borneol to melt fully, and elimination impurity obtains the 3rd medicine oil; (5) get 20 kilograms of calcined gypsums, 10 kilograms of pseudo-ginseng, 20 kilograms of broken abrasive dusts of dragon's blood, require powder particle to pass through 100 mesh sieves, radiation sterilization; Add the powder that step (5) obtains in (6) the 3rd medicine oil, stir, obtain the ointment of said externally applied drug.
Embodiment 6: every part is 1 jin
A kind of external preparation for skin medicine of treating burn and scald, its preparation method is: (1) get 28 jin of rheum officinales, 10 jin of Radix Angelicae Sinensis, 22 jin of Asian puccoons, 28 jin of cape jasmines, 25 jin of honeysuckles, 16 jin of garden burnets, 20 jin of dried rhizome of rehmannia, 10 jin of RADIX PAEONIAE RUBRAs, 25 jin of rhizome of chuanxiong strippings and slicings, immerse 9h in 300 jin the sesame oil; (2) immersion is had the sesame oil of medicinal material boil to medicinal material and be coke yellow, oily temperature is 90 ℃, and the elimination dregs of a decoction obtain first medicine oil; (3) first medicine oil are cooled to 50 ℃, add 35 jin beeswax, are stirred to beeswax and melt fully, obtain second medicine oil; (4) second medicine oil are cooled to 23 ℃, add 15 jin of borneols and be stirred to borneol to melt fully, and elimination impurity obtains the 3rd medicine oil; (5) get 5 jin of calcined gypsums, 15 jin of pseudo-ginseng, 13 jin of broken abrasive dusts of dragon's blood, require powder particle to pass through 100 mesh sieves, radiation sterilization; Add the powder that step (5) obtains in (6) the 3rd medicine oil, stir, obtain the ointment of said externally applied drug.
Claims (2)
1. an external preparation for skin medicine of treating burn and scald is characterized in that, is to be made by the raw material of following parts by weight, 20～30 parts of rheum officinales; 10～20 parts of Radix Angelicae Sinensis, 10～25 parts of Asian puccoons, 10～30 parts of cape jasmines, 10～30 parts of honeysuckles; 15～20 parts of garden burnets, 10～20 parts in the dried rhizome of rehmannia, 10～20 parts of RADIX PAEONIAE RUBRAs, 15～25 parts of rhizome of chuanxiongs; 5～20 parts of calcined gypsums, 5～20 parts of pseudo-ginseng, 5～20 parts of dragon's blood, 5～15 parts of borneols.
2. the external preparation for skin medicine of treatment burn and scald according to claim 1; It is characterized in that its preparation method is: (1) get rheum officinale, Radix Angelicae Sinensis, Asian puccoon, cape jasmine, honeysuckle, garden burnet, the dried rhizome of rehmannia, RADIX PAEONIAE RUBRA, rhizome of chuanxiong stripping and slicing, immerse 6～10h in 300～800 parts the sesame oil; (2) immersion is had the sesame oil of medicinal material boil to medicinal material and be coke yellow, oily temperature is 90～100 ℃, and the elimination dregs of a decoction obtain first medicine oil; (3) first medicine oil are cooled to 40～50 ℃, add 20～50 parts beeswax, are stirred to beeswax and melt fully, obtain second medicine oil; (4) second medicine oil are cooled to 15～25 ℃, add borneol and be stirred to borneol to melt fully, and elimination impurity obtains the 3rd medicine oil; (5) get calcined gypsum, pseudo-ginseng, the broken abrasive dust of dragon's blood, require powder particle to pass through 100 mesh sieves, radiation sterilization; Add the powder that step (5) obtains in (6) the 3rd medicine oil, stir, obtain the ointment of said externally applied drug.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103230471A (en) * | 2013-05-06 | 2013-08-07 | 湖南省宝灵医药器械有限公司 | Externally used drug for treating burns and scalds and preparation method thereof |
| CN104840888A (en) * | 2015-05-22 | 2015-08-19 | 李兆霞 | Traditional Chinese medicine ointment for promoting wound healing |
| CN104997837A (en) * | 2014-04-22 | 2015-10-28 | 河北盛唐园林科技开发有限公司 | Novel scald drug and preparation method thereof |
| CN105311370A (en) * | 2015-06-14 | 2016-02-10 | 国网山东兰陵县供电公司 | Preparation for treating electric burn and preparation process of preparation for treating electric burn |
| CN108686101A (en) * | 2018-07-30 | 2018-10-23 | 王解生 | A kind of herbal composite promoting organization healing |
| CN109700926A (en) * | 2019-03-11 | 2019-05-03 | 潘连芳 | A kind of preparation method for treating burn and scald externally applied drug |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1177490A (en) * | 1997-09-17 | 1998-04-01 | 孙明忠 | Oil ointment of chirita longangensis for treating burns |
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2012
- 2012-06-20 CN CN201210204379.9A patent/CN102688360B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1177490A (en) * | 1997-09-17 | 1998-04-01 | 孙明忠 | Oil ointment of chirita longangensis for treating burns |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103230471A (en) * | 2013-05-06 | 2013-08-07 | 湖南省宝灵医药器械有限公司 | Externally used drug for treating burns and scalds and preparation method thereof |
| CN103230471B (en) * | 2013-05-06 | 2015-03-25 | 湖南省宝灵医药器械有限公司 | Externally used drug for treating burns and scalds and preparation method thereof |
| CN104997837A (en) * | 2014-04-22 | 2015-10-28 | 河北盛唐园林科技开发有限公司 | Novel scald drug and preparation method thereof |
| CN104840888A (en) * | 2015-05-22 | 2015-08-19 | 李兆霞 | Traditional Chinese medicine ointment for promoting wound healing |
| CN105311370A (en) * | 2015-06-14 | 2016-02-10 | 国网山东兰陵县供电公司 | Preparation for treating electric burn and preparation process of preparation for treating electric burn |
| CN108686101A (en) * | 2018-07-30 | 2018-10-23 | 王解生 | A kind of herbal composite promoting organization healing |
| CN109700926A (en) * | 2019-03-11 | 2019-05-03 | 潘连芳 | A kind of preparation method for treating burn and scald externally applied drug |
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| CN102688360B (en) | 2014-03-26 |
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