CN102671725B - 微芯片、液体样本供给装置及供给方法以及分析装置 - Google Patents

微芯片、液体样本供给装置及供给方法以及分析装置 Download PDF

Info

Publication number
CN102671725B
CN102671725B CN201210062191.5A CN201210062191A CN102671725B CN 102671725 B CN102671725 B CN 102671725B CN 201210062191 A CN201210062191 A CN 201210062191A CN 102671725 B CN102671725 B CN 102671725B
Authority
CN
China
Prior art keywords
microchip
liquid sample
flow path
gas
liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201210062191.5A
Other languages
English (en)
Chinese (zh)
Other versions
CN102671725A (zh
Inventor
高清水亨
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sony Corp
Original Assignee
Sony Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sony Corp filed Critical Sony Corp
Publication of CN102671725A publication Critical patent/CN102671725A/zh
Application granted granted Critical
Publication of CN102671725B publication Critical patent/CN102671725B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082—Test tubes per se
    • B01L3/50825—Closing or opening means, corks, bungs
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/141—Preventing contamination, tampering
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes
    • G01N2021/058—Flat flow cell

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
CN201210062191.5A 2011-03-18 2012-03-09 微芯片、液体样本供给装置及供给方法以及分析装置 Expired - Fee Related CN102671725B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2011060896A JP5754190B2 (ja) 2011-03-18 2011-03-18 マイクロチップ、サンプル液供給装置、サンプル液供給方法及び分析装置
JP2011-060896 2011-03-18

Publications (2)

Publication Number Publication Date
CN102671725A CN102671725A (zh) 2012-09-19
CN102671725B true CN102671725B (zh) 2015-09-16

Family

ID=46804661

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201210062191.5A Expired - Fee Related CN102671725B (zh) 2011-03-18 2012-03-09 微芯片、液体样本供给装置及供给方法以及分析装置

Country Status (3)

Country Link
US (1) US9429512B2 (enExample)
JP (1) JP5754190B2 (enExample)
CN (1) CN102671725B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10632465B2 (en) * 2015-04-22 2020-04-28 Stilla Technologies Contact-less priming method for loading a solution in a microfluidic device and associated system
WO2018187207A2 (en) 2017-04-06 2018-10-11 Illumina, Inc. In-situ fluidic inspection
WO2021100620A1 (ja) * 2019-11-20 2021-05-27 ソニーグループ株式会社 粒子分取キット
WO2021261399A1 (ja) 2020-06-22 2021-12-30 積水化学工業株式会社 検査チップおよび液体導入方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5163582A (en) * 1991-04-30 1992-11-17 Andronic Devices Ltd. Apparatus and method for aliquotting blood serum or blood plasma
CN1715903A (zh) * 2005-06-27 2006-01-04 浙江大学 微流控芯片负压进样和分离的装置
CN1898560A (zh) * 2003-12-23 2007-01-17 法斯特拉克公司 现场即时诊断平台
CN1991370A (zh) * 2005-12-29 2007-07-04 财团法人工业技术研究院 微流体驱动及速度控制装置与方法
JP2010133843A (ja) * 2008-12-05 2010-06-17 Sony Corp サンプル液供給方法及び容器

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5400923A (en) * 1988-06-20 1995-03-28 Helena Laboratories Corporation Apparatus for discharging contents of a sealed container
US5571410A (en) * 1994-10-19 1996-11-05 Hewlett Packard Company Fully integrated miniaturized planar liquid sample handling and analysis device
US6398956B1 (en) * 1999-05-28 2002-06-04 Bio/Data Corporation Method and apparatus for directly sampling a fluid for microfiltration
JP3669363B2 (ja) 2003-03-06 2005-07-06 ソニー株式会社 エレクトロデポジション型表示パネルの製造方法、並びにエレクトロデポジション型表示パネルおよびエレクトロデポジション型表示装置
WO2005065157A2 (en) * 2003-12-23 2005-07-21 Fastraq, Inc. Point of care diagnostic platform
JP2008008880A (ja) 2006-06-02 2008-01-17 Sumitomo Bakelite Co Ltd プラスチック製マイクロチップ、及びその製造方法、並びにそれを利用したバイオチップ又はマイクロ分析チップ
JP2008064545A (ja) 2006-09-06 2008-03-21 Kowa Co マイクロチップ及びマイクロチップ装置
CN103495439B (zh) * 2007-05-04 2015-09-16 欧普科诊断有限责任公司 流体连接器和微流体系统
EP2087934A1 (de) * 2008-02-07 2009-08-12 Qiagen GmbH Verfahren und Vorrichtung zur automatisierten Prozessierung einer Probe
JP5049404B2 (ja) * 2008-03-31 2012-10-17 エージェンシー フォー サイエンス， テクノロジー アンド リサーチ 相互接続マルチチャンバデバイスを使用する流体処理および移送の方法
WO2010118427A1 (en) * 2009-04-10 2010-10-14 Canon U.S. Life Sciences, Inc. Fluid interface cartridge for a microfluidic chip
GB0913228D0 (en) * 2009-07-29 2009-09-02 Iti Scotland Ltd Loading element

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5163582A (en) * 1991-04-30 1992-11-17 Andronic Devices Ltd. Apparatus and method for aliquotting blood serum or blood plasma
CN1898560A (zh) * 2003-12-23 2007-01-17 法斯特拉克公司 现场即时诊断平台
CN1715903A (zh) * 2005-06-27 2006-01-04 浙江大学 微流控芯片负压进样和分离的装置
CN1991370A (zh) * 2005-12-29 2007-07-04 财团法人工业技术研究院 微流体驱动及速度控制装置与方法
JP2010133843A (ja) * 2008-12-05 2010-06-17 Sony Corp サンプル液供給方法及び容器

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
孙毓庆.微流控芯片检测系统.《现代色谱法及其在药物分析中的应用》.2005, *

Also Published As

Publication number Publication date
JP2012198050A (ja) 2012-10-18
US9429512B2 (en) 2016-08-30
US20120236312A1 (en) 2012-09-20
JP5754190B2 (ja) 2015-07-29
CN102671725A (zh) 2012-09-19

Similar Documents

Publication Publication Date Title
CN1862260B (zh) 液体输送器件及分析系统
CN104487562B (zh) 生化处理装置
US11007523B2 (en) Injection molded microfluidic/fluidic cartridge integrated with silicon-based sensor
JP5218443B2 (ja) マイクロチップ及びマイクロチップの製造方法
US10137450B2 (en) Microfluidics cartridge with pipetting guide
US9180451B2 (en) Fluidic cartridge for detecting chemicals in samples, in particular for performing biochemical analyses
JP4721414B2 (ja) 反応カートリッジ、反応装置および反応カートリッジの溶液の移動方法
CN112261996B (zh) 微流体装置及其制造方法和应用
JP6676611B2 (ja) マイクロ流体チップ、その製造方法及びそれを用いた分析装置
CN111212900B (zh) 细胞捕获装置
CN102671725B (zh) 微芯片、液体样本供给装置及供给方法以及分析装置
US12194465B2 (en) Structures for automated, multi-stage processing of nanofluidic chips
US10799866B2 (en) Microfluidic chip
WO2015119471A1 (ko) 미세유체 칩 및 이를 이용한 실시간 분석 장치
CN1846856A (zh) 具有自密封流体端口的设备
WO2006092959A1 (ja) マイクロ流路及びマイクロ流体チップ
WO2009081722A1 (ja) マイクロチップ及びマイクロチップの送液方法
US20140010733A1 (en) Interface device for bio-chip
US20090226346A1 (en) Dispensing device
JP2010133843A (ja) サンプル液供給方法及び容器
JP3967331B2 (ja) 液体混合方法、液体混合装置およびマイクロチップ
JP6627580B2 (ja) マイクロチップ電気泳動装置
KR101337587B1 (ko) 미세입자 측면 주입을 위한 유체 연결 장치 및 이를 이용한 미세채널 내부로의 미세입자 주입방법
JP2013101154A (ja) マイクロチップ及びマイクロチップの製造方法
US20110014619A1 (en) Reaction treatment apparatus and reaction treatment method

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20150916

Termination date: 20210309