CN102671148A

CN102671148A - Traditional Chinese medicine ointment for curing condyloma acuminatum

Info

Publication number: CN102671148A
Application number: CN2012101826289A
Authority: CN
Inventors: 侯峰; 杨秋兰
Original assignee: Individual
Current assignee: Individual
Priority date: 2012-05-31
Filing date: 2012-05-31
Publication date: 2012-09-19
Anticipated expiration: 2032-05-31
Also published as: CN102671148B

Abstract

Traditional Chinese medicine ointment for curing condyloma acuminatum is prepared by the steps: (1) soaking curcuma zedoary and horsetail with water for 2 hours and using a volatile oil extractor to extract volatile oil for standby; (2) adding curcuma zedoary and horsetail dregs into codonopsis pilosula, bighead atractylodes rhizome, semen coicis, herbal portulacae, gallnuts, granatum, isatis roots, rhizoma smilacis glabrae, polygonum cuspidatum, lithospermum, fructus forsythiae, dandelion and plantain herb which are soaked for 1 hour, using a multifunctional extractor to perform extraction for two times and concentrating an extractive to be thick for standby, wherein 1 hour is required for each extraction; (3) using stearic acid 16g, white vaseline 20g, glycerol monostearate 30g, glycerol 60g, triethanolamine 5mL, lauryl sodium sulfate 3.3g, laurocapram 10g, ethyl p-hydroxybenzoate 1g and an appropriate amount of distilled water to prepare emulsified matrix 1000g; and (4) according to the proportion 1:4 of medicine thick ointment to the emulsified matrix, heating and dissolving the emulsified matrix, adding the medicine thick ointment prepared in the step (2) and the volatile oil prepared in the step (1) into the emulsified matrix under the condition of continuous stirring, and performing the stirring till a mixture is condensates.

Description

A kind of traditional Chinese herb medicine of treating condyloma acuminatum

Technical field:

The invention belongs to technical field of Chinese medicines, particularly a kind of traditional Chinese herb medicine of treating condyloma acuminatum.

Background technology:

Condyloma acuminatum is by a kind of common sexually transmitted disease (STD) due to the human papilloma virus infection; Main trafficability characteristic contagion, clinical manifestation is genitals, anal skin mucosa spininess projection, surface wettability; Often outbreak repeatedly; Methods such as the outer wiping of common drug clinically at present, laser, freezing and operative treatment all can be removed the wart body, but all have the possibility of recurrence.The interferon therapy expense is big, and side effect is big, is difficult to generally accept for clinical; Chinese medicine can treating both the principal and secondary aspects of a disease, and advantage is from organic conception, when improving the resistance against diseases of body; Note local application, can make the medicine pathological tissues that goes directly, be beneficial to absorption; Prevent traumatic infection and edema, promote wound healing, satisfactory effect.

Summary of the invention:

The present invention provides a kind of traditional Chinese herb medicine of treating condyloma acuminatum, and the prescription of this invention is: Radix Codonopsis 20 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, Herba Portulacae 30 grams, Galla Chinensis 30 grams, Pericarpium Granati 20 grams, Radix Isatidis 30 grams, Rhizoma Smilacis Glabrae 20 grams, Rhizoma Curcumae 30 grams, Herba Equiseti Hiemalis's 10 grams, Rhizoma Polygoni Cuspidati 30 grams, Radix Arnebiae (Radix Lithospermi) 30 grams, Semen Coicis 10 grams, Fructus Forsythiae 15 grams, Herba Taraxaci 15 grams and Herba Plantaginis 15 grams.

Its manufacture method is: soak Rhizoma Curcumae, Herba Equiseti Hiemalis 2 hours (1), extracts volatile oil with volatile oil extractor, subsequent use; (2) Rhizoma Curcumae, Herba Equiseti Hiemalis's medicinal residues add Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Semen Coicis, Herba Portulacae, Galla Chinensis, Pericarpium Granati, Radix Isatidis, Rhizoma Smilacis Glabrae, Rhizoma Polygoni Cuspidati, Radix Arnebiae (Radix Lithospermi), Fructus Forsythiae, Herba Taraxaci and the Herba Plantaginis of having soaked 1 hour; Extract 2 times with multi-functional extractor; Each 1 hour, be concentrated into thick paste, subsequent use; (3) substrate preparation: stearic acid 16g, white vaseline 20g, glyceryl monostearate 30g, glycerol 60g, triethanolamine 5mL, sodium lauryl sulphate 3.3g, laurocapram 10g, ethyl hydroxybenzoate 1g and aquae destillata are processed the 1000g emulsifying base in right amount; (4) in medicine thick paste and 1: 4 ratio of emulsifying base, the emulsifying base heating is dissolved, under constantly stirring, make the volatile oil that makes in medicine thick paste and (1) step in adding (2) step, be stirred to condensation and get final product.

The method for making explanation: Rhizoma Curcumae, Herba Equiseti Hiemalis are contained volatile oil, so extract volatile oil with volatile oil extractor.Utilize short Transdermal absorption substrate to process ointment, help drug transdermal and absorb.

Mechanism: the Radix Codonopsis QI invigorating is set upright, the Rhizoma Atractylodis Macrocephalae, Semen Coicis spleen invigorating eliminating dampness by diuresis, Rhizoma Polygoni Cuspidati, Radix Arnebiae (Radix Lithospermi), Herba Portulacae heat-clearing and toxic substances removing, invigorate blood circulation, the dampness eliminating stagnation, Galla Chinensis, Pericarpium Granati convergence granulation promoting, Radix Isatidis, Rhizoma Smilacis Glabrae clearing away heat-damp and promoting diuresis, Rhizoma Curcumae, the Herba Equiseti Hiemalis's removing blood stasis with potent drugs wart that disappears.Modern pharmacological research proves: Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae have the enhances human body immunity function, and Radix Isatidis Rhizoma Polygoni Cuspidati Radix Arnebiae (Radix Lithospermi) has antivirus action, Fructus Forsythiae, Herba Taraxaci heat-clearing and toxic substances removing; Toxin expelling is convenient in the Herba Plantaginis diuresis; All medicines share, damp eliminating detoxifcation, the QI and blood regulating, strengthening vital QI to eliminate pathogenic factors, and treating both the principal and secondary aspects of a disease is promptly transferred the anti-evil ability of body, improves local environment again, is unfavorable for virus existence, duplicates.

The specific embodiment:

A kind of traditional Chinese herb medicine of treating condyloma acuminatum, the prescription of this invention is: Radix Codonopsis 20 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, Herba Portulacae 30 grams, Galla Chinensis 30 grams, Pericarpium Granati 20 grams, Radix Isatidis 30 grams, Rhizoma Smilacis Glabrae 20 grams, Rhizoma Curcumae 30 grams, Herba Equiseti Hiemalis's 10 grams, Rhizoma Polygoni Cuspidati 30 grams, Radix Arnebiae (Radix Lithospermi) 30 grams, Semen Coicis 10 grams, Fructus Forsythiae 15 grams, Herba Taraxaci 15 grams and Herba Plantaginis 15 grams.Its manufacture method is: soak Rhizoma Curcumae, Herba Equiseti Hiemalis 2 hours (1), extracts volatile oil with volatile oil extractor, subsequent use; (2) Rhizoma Curcumae, Herba Equiseti Hiemalis's medicinal residues add Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Semen Coicis, Herba Portulacae, Galla Chinensis, Pericarpium Granati, Radix Isatidis, Rhizoma Smilacis Glabrae, Rhizoma Polygoni Cuspidati, Radix Arnebiae (Radix Lithospermi), Fructus Forsythiae, Herba Taraxaci and the Herba Plantaginis of having soaked 1 hour; Extract 2 times with multi-functional extractor; Each 1 hour, be concentrated into thick paste, subsequent use; (3) substrate preparation: stearic acid 16g, white vaseline 20g, glyceryl monostearate 30g, glycerol 60g, triethanolamine 5mL, sodium lauryl sulphate 3.3g, laurocapram 10g, ethyl hydroxybenzoate 1g and aquae destillata are processed the 1000g emulsifying base in right amount; (4) in medicine thick paste and 1: 4 ratio of emulsifying base, the emulsifying base heating is dissolved, under constantly stirring, make the volatile oil that makes in medicine thick paste and (1) step in adding (2) step, be stirred to condensation and get final product.

Clinical verification: include standard in: 1, contact history: have unmarried sexual behaviour history or spouse to infect history or indirect infection history.2, locate to occur a plurality of pale reds, the faint yellow or tiny pimple of dark brown around genitals, perineum or the anus etc., rough surface, not of uniform size, little like syringe needle, greatly like Semen phaseoli radiati; Diffusion towards periphery increases, increases, and is the vegetation of pimple appearance, nipple appearance, cauliflower form, gill fungus shape projection.Smear the skin lesion place with 5% acetate solution, bleached in 3～5 minutes, the part naked eyes are difficult to judgement person and make a definite diagnosis through nucleic acid hybridization and nucleic acid amplification technologies or histopathology check.

Criterion of therapeutical effect: the visible wart body of naked eyes is eliminated fully, and treats in back 3 months sick damage place and do not occur newborn wart body again and be recovery from illness; Treat and occurred new wart body in back 3 months around the inherent former diseased region level for recurring; In March behind the removal wart body, per 2 weeks check once, and whether observe has new wart body.

The treatment group with Warm Wash after the ointment of external condyloma acuminatum, logotype 30 days;

Matched group adds 2% lignocaine dilution back with interferon 1,000,000 U and injects wart body, logotype 30 days.

Result: the 25 example recoveries from illness of treatment group, 6 example recurrences; And matched group 18 example recoveries from illness, 15 example recurrences.

The curative effect significant difference.

Model case is introduced:

1, Huang, the man 28 years old, likes the entertainment place; Occurred femoribus internus difference afterwards, genitals has the pale red pimple, does not take notice of, cumulatively afterwards increases greatly; The surface is rough and uneven in surface, moistening and soft, is the nipple appearance that varies in size, and being prone to of touching is hemorrhage; Pruritus, the erosion of grabbing, sometimes with purulent secretion, removing examination in hospital is condyloma acuminatum.Give for oral administration and this traditional Chinese herb medicine of external with heat-clearing and detoxifying herb, gargalesthesia obviously alleviates after 15 days, continues to strengthen recovery from illness 20 days.

2, certain woman, 36 years old, husband businessman treated with courtesy many outside; Full-time Mrs, conceived back is lived through the married woman's parents' home that is everlasting because of morning sickness, and pruritus vulvae and leucorrhoea grow in quantity are not taken notice of sometimes; When pregnant inspection, find genital herpes, conceived 6 months, select treatment by Chinese herbs to reduce influence to fetus; The Chinese medicine of raise immunity cooperates the external of this Chinese medicinal ointment, treats 20 days, rechecks normal.Check afterwards is not recurrence also.

3, man, 35 years old, genitals had the pale red pimple, pruritus, the erosion of grabbing, sometimes with purulent secretion, removing examination in hospital is condyloma acuminatum.This traditional Chinese herb medicine of external, gargalesthesia obviously alleviates after 20 days, continues to strengthen recovery from illness 10 days.

4, woman, 23 years old, the city service man that practises singing, pruritus vulvae and leucorrhoea grow in quantity are not taken notice of, find genital herpes during inspection, the external of this Chinese medicinal ointment was treated 20 days, rechecked normal.Check afterwards is not recurrence also.

Claims

1. traditional Chinese herb medicine of treating condyloma acuminatum; It is characterized in that: the prescription of this invention is Radix Codonopsis 20 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, Herba Portulacae 30 grams, Galla Chinensis 30 grams, Pericarpium Granati 20 grams, Radix Isatidis 30 grams, Rhizoma Smilacis Glabrae 20 grams, Rhizoma Curcumae 30 grams, Herba Equiseti Hiemalis's 10 grams, Rhizoma Polygoni Cuspidati 30 grams, Radix Arnebiae (Radix Lithospermi) 30 grams, Semen Coicis 10 grams, Fructus Forsythiae 15 grams, Herba Taraxaci 15 grams and Herba Plantaginis 15 grams.

2. a kind of traditional Chinese herb medicine of treating condyloma acuminatum according to claim 1 is characterized in that: soak Rhizoma Curcumae, Herba Equiseti Hiemalis 2 hours (1), extracts volatile oil with volatile oil extractor, subsequent use; (2) Rhizoma Curcumae, Herba Equiseti Hiemalis's medicinal residues add Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Semen Coicis, Herba Portulacae, Galla Chinensis, Pericarpium Granati, Radix Isatidis, Rhizoma Smilacis Glabrae, Rhizoma Polygoni Cuspidati, Radix Arnebiae (Radix Lithospermi), Fructus Forsythiae, Herba Taraxaci and the Herba Plantaginis of having soaked 1 hour; Extract 2 times with multi-functional extractor; Each 1 hour, be concentrated into thick paste, subsequent use; (3) substrate preparation: stearic acid 16g, white vaseline 20g, glyceryl monostearate 30g, glycerol 60g, triethanolamine 5mL, sodium lauryl sulphate 3.3g, laurocapram 10g, ethyl hydroxybenzoate 1g and aquae destillata are processed the 1000g emulsifying base in right amount; (4) in medicine thick paste and 1: 4 ratio of emulsifying base, the emulsifying base heating is dissolved, under constantly stirring, make the volatile oil that makes in medicine thick paste and (1) step in adding (2) step, be stirred to condensation and get final product.