CN102670921A - 一种治疗小儿湿疹的中药外洗剂 - Google Patents
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Abstract
本发明公开了一种治疗小儿湿疹的中药外洗剂。中医认为小儿湿疹虽形于外面实发于内，多由于脾虚失健运，湿从内生，侵淫肌肤而生湿疹。为此，本发明选择具有清热、凉血、利湿为的中药黄连、苦参、连翘、马齿苋、紫花地丁、茯苓、白术、小柿子叶、酸水草、山药藤、浮萍制成外洗剂，经我院临床试验，治愈率、总有效率分别达到69.44％、93.05％，均优于对照组，特别是复发率低，值得临床推广应用。
Description
技术领域
本发明涉及一种中药组合物，尤其涉及一种用中草药制成的治疗小儿湿疹的中药外洗剂。
背景技术
湿疹是婴幼儿常见病，多由于母亲胎传或居所湿热而致使小儿发病。起初多为红色细小丘疹、瘙痒，继而发为红斑、脱屑、水泡、糜烂或渗液等。患儿表现轻重不同，病程也有长短，反复发作，缠绵难愈，严重影响婴幼儿的身体健康和正常发育。西医主要用激素、抗过敏药以及近年来应用于临床的钙调神经磷酸酶抑制剂来治疗，均是对症治疗或局部治疗，无法根治，明显的不良反应使其应用受到诸多限制。
发明内容
本发明提供一种治疗小儿湿疹的中药外洗剂。中医认为小儿湿疹虽形于外面实发于内，多由于脾虚失健运，湿从内生，侵淫肌肤而生湿疹。目前中医药治疗本病多以清热、凉血、利湿为治则。
本发明的目的是通过以下技术方案实现的，该治疗小儿湿疹的中药外洗剂由以下重量份的中药制成：黄连10-15份、苦参10-15份、连翘12-15份、马齿苋15-20份、紫花地丁15-20份、茯苓15-20份、白术10-15份、小柿子叶10-15份、酸水草10-15份、山药藤10-15份、浮萍15-20份。
优选的，该治疗小儿湿疹的中药外洗剂由以下重量份的中药制成：黄连12份、苦参12份、连翘14份、马齿苋18份、紫花地丁18份、茯苓18份、白术13份、小柿子叶13份、酸水草13份、山药藤12份、浮萍18份。
上药用凉水5000ml浸泡1小时，煎取药液3000ml，候冷弃渣，用纱布湿敷患处，每剂可煎2遍，1天洗2次，每日1剂，5天1疗程。
方中：黄连：归心、胃、肝、大肠经；清热燥湿，泻火解毒。
苦参：归心、肝、胃、大肠、膀胱经；清热澡湿，祛风杀虫，利尿。
连翘：入肺经、心经、胆经，肝经；清热解毒，疏散风热，消痈散结。马齿苋：归肝、大肠经；清热解毒，凉血止血。
紫花地丁：归心、肝经；清热解毒，消痈散结。
茯苓：归心、脾、肾经；利水渗湿，健脾安神。
白术：归脾、胃经；补气健脾，燥湿利水。
小柿子叶：燥湿止痒，收敛止血，主治湿疹，皮炎。
酸水草：治湿疹、皮肤瘙痒症。
山药藤：燥湿解毒，治皮肤湿疹。
浮萍：归肺、膀胱经；发汗解表，透疹止痒，利水消肿。
临床资料
1、一般资料 所有病例均来自2008年2月～2009年2月本院皮肤科门诊，共收集病例122例，将患者随机分为两组，治疗组72例，对照组50例，两组患者在年龄、性别、病程、皮损分布、症状等方面无显著差异(P＜0.05)，具有可比性。
2、诊断标准 符合美国皮肤学会特应性皮炎诊断标准[3]中的必备两项指标即可诊断。即(1)瘙痒；(2)具备典型表现及年龄特征，婴儿面、颈及肢体屈侧急性、亚急性、慢性湿疹。排除疥疮、脂溢性皮炎、接触性皮炎、银屑病、鱼鳞病等。
3、治疗方法 治疗组：取本发明所述的外洗剂3000ml，候冷弃渣，用纱布湿敷患处，每剂可煎2遍，1天洗2次，每日1剂；对照组：服氟雷他定颗粒剂(南京亿华药业有限公司生产)，2～12岁儿童，体重＞30kg，每天一次，每次2包(10mg)；体重≤30kg，每天一次，每次1包(5mg)，每晚1次。两组均为5天为一个疗程。
4、疗效标准 参照国家中医药管理局颁发的《中医病证诊断疗效标准》[4]拟定。临床(1)治愈：皮损完全消退，自觉症状消失。(2)显效：皮损消退70％以上，自觉症状明显改善。(3)有效：皮损消退30％以上，自觉症状有所改善。(4)无效：皮损消退30％以下，自觉症状无明显改善。
5、治疗结果 两组临床疗效比较：治疗组与对照组相比，治愈率、总有效率均有显著性差异(P＜0.01)见表1
表1两组临床疗效比较
两组痊愈病例复发情况比较 对两组痊愈患者进行一个月的随访，对各自的复发情况作比较，发现治疗组复发率明显低于对照组(P＜0.05)，见表2
表2治愈1个月随访结果
典型病例：患儿李某，女，10个月，颜面、头皮、躯干处泛发红色斑丘疹1个月。诊见头皮、颜面、躯干可见红色斑丘疹，头皮有黄白色鳞屑，结厚痂，查血常规正常。给予上述中药外洗，3剂后皮疹大部分消退，再用4剂，皮损完全消退。随诊5个月未见复发。
具体实施方式
实施例一：称取黄连12g、苦参12g、连翘14g、马齿苋18g、紫花地丁18g、茯苓18g、白术13g、小柿子叶13g、酸水草13g、山药藤12g、浮萍18g，上药用凉水5000ml浸泡1小时，煎取药液3000ml，候冷弃渣，用纱布湿敷患处，每剂可煎2遍，1天洗2次，每日1剂。
实施例二：称取黄连10g、苦参10g、连翘12g、马齿苋15g、紫花地丁15g、茯苓15g、白术10g、小柿子叶10g、酸水草10g、山药藤10g、浮萍15g，上药用凉水4500ml浸泡1小时，煎取药液3000ml，候冷弃渣，有纱布湿敷患处，每剂可煎2遍，1天洗2次，每日1剂。
实施例三：称取黄连15g、苦参15g、连翘15g、马齿苋20g、紫花地丁20g、茯苓20g、白术15g、小柿子叶15g、酸水草15g、山药藤15g、浮萍20g，上药用凉水5500ml浸泡1小时，煎取药液3000ml，候冷弃渣，有纱布湿敷患处，每剂可煎2遍，1天洗2次，每日1剂。
Claims (2)
1.一种治疗小儿湿疹的中药外洗剂，其特征在于该中药外洗剂由以下重量份的中药制成：黄连10-15份、苦参10-15份、连翘12-15份、马齿苋15-20份、紫花地丁15-20份、茯苓15-20份、白术10-15份、小柿子叶10-15份、酸水草10-15份、山药藤10-15份、浮萍15-20份。
2.根据权利要求1所述的一种治疗小儿湿疹的中药外洗剂，其特征在于该中药外洗剂由以下重量份的中药制成：黄连12份、苦参12份、连翘14份、马齿苋18份、紫花地丁18份、茯苓18份、白术13份、小柿子叶13份、酸水草13份、山药藤12份、浮萍18份。
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Cited By (3)
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| CN105796643A (zh) * | 2016-03-24 | 2016-07-27 | 刘吉伟 | 一种治疗小儿湿疹的中药洗剂及护理方法 |
| CN105796807A (zh) * | 2016-04-29 | 2016-07-27 | 欧卉 | 一种治疗急性湿疹的外敷药 |
| CN105902926A (zh) * | 2016-05-07 | 2016-08-31 | 庄海涛 | 一种治疗小儿湿疹的中药外洗剂 |
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| CN1262943A (zh) * | 1999-02-09 | 2000-08-16 | 夏进 | 皮肤消炎、镇痛、抑疤软膏 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105796643A (zh) * | 2016-03-24 | 2016-07-27 | 刘吉伟 | 一种治疗小儿湿疹的中药洗剂及护理方法 |
| CN105796807A (zh) * | 2016-04-29 | 2016-07-27 | 欧卉 | 一种治疗急性湿疹的外敷药 |
| CN105902926A (zh) * | 2016-05-07 | 2016-08-31 | 庄海涛 | 一种治疗小儿湿疹的中药外洗剂 |
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