CN102657863A - 用于活性药剂的低温制粒和贮藏的方法 - Google Patents

用于活性药剂的低温制粒和贮藏的方法 Download PDF

Info

Publication number
CN102657863A
CN102657863A CN2011104367586A CN201110436758A CN102657863A CN 102657863 A CN102657863 A CN 102657863A CN 2011104367586 A CN2011104367586 A CN 2011104367586A CN 201110436758 A CN201110436758 A CN 201110436758A CN 102657863 A CN102657863 A CN 102657863A
Authority
CN
China
Prior art keywords
cryogenic particles
container
allergen
cryogenic
particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2011104367586A
Other languages
English (en)
Chinese (zh)
Inventor
M·瑞彻特-福瑞斯
S·科尔姆斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ALK Abello AS
Original Assignee
ALK Abello AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ALK Abello AS filed Critical ALK Abello AS
Publication of CN102657863A publication Critical patent/CN102657863A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B01J2/06—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a liquid medium
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • F26B5/065—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing the product to be freeze-dried being sprayed, dispersed or pulverised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Glanulating (AREA)
CN2011104367586A 2003-12-19 2004-12-17 用于活性药剂的低温制粒和贮藏的方法 Pending CN102657863A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DKPA200301896 2003-12-19
DKPA200301896 2003-12-19
US53167903P 2003-12-23 2003-12-23
US60/531,679 2003-12-23

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN2004800378113A Division CN1894026B (zh) 2003-12-19 2004-12-17 用于活性药剂的低温制粒和贮藏的方法

Publications (1)

Publication Number Publication Date
CN102657863A true CN102657863A (zh) 2012-09-12

Family

ID=34973435

Family Applications (2)

Application Number Title Priority Date Filing Date
CN2011104367586A Pending CN102657863A (zh) 2003-12-19 2004-12-17 用于活性药剂的低温制粒和贮藏的方法
CN2004800378113A Expired - Fee Related CN1894026B (zh) 2003-12-19 2004-12-17 用于活性药剂的低温制粒和贮藏的方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN2004800378113A Expired - Fee Related CN1894026B (zh) 2003-12-19 2004-12-17 用于活性药剂的低温制粒和贮藏的方法

Country Status (6)

Country Link
JP (1) JP4755992B2 (da)
CN (2) CN102657863A (da)
AT (1) ATE505263T1 (da)
DE (1) DE602004032262D1 (da)
DK (1) DK1697033T3 (da)
ES (1) ES2363342T3 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103127173B (zh) * 2013-03-06 2015-01-21 苏州市红冠庄国药饮片有限公司 生产鹿血晶的雾化多层覆盖结晶工艺
CN114160040B (zh) * 2021-12-09 2022-07-12 广州风行乳业股份有限公司 一种液氮深冷制粒设备

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000006179A1 (en) * 1998-07-31 2000-02-10 Eli Lilly And Company Cryogranulation of activated protein c
WO2002040676A2 (en) * 2000-11-16 2002-05-23 Alk-Abelló A/S Mutant allergens

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5242846B2 (da) * 1974-04-03 1977-10-27
DE60141680D1 (de) * 2000-01-14 2010-05-12 Univ Brown Res Found Verfahren zur herstellung von mikronisierte gefriergetrocknete partikeln
AUPR750501A0 (en) * 2001-09-05 2001-09-27 Gauci, Mark Products comprising quantum of bioparticles and method for production thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000006179A1 (en) * 1998-07-31 2000-02-10 Eli Lilly And Company Cryogranulation of activated protein c
WO2002040676A2 (en) * 2000-11-16 2002-05-23 Alk-Abelló A/S Mutant allergens

Also Published As

Publication number Publication date
DE602004032262D1 (de) 2011-05-26
JP2007514490A (ja) 2007-06-07
CN1894026B (zh) 2012-01-25
ATE505263T1 (de) 2011-04-15
ES2363342T3 (es) 2011-08-01
JP4755992B2 (ja) 2011-08-24
CN1894026A (zh) 2007-01-10
DK1697033T3 (da) 2011-06-27

Similar Documents

Publication Publication Date Title
JP5795852B2 (ja) 有効医薬成分の寒冷顆粒化及び貯蔵の方法
CA1097233A (en) Packages
EP2812053B1 (en) Device for accommodating a freeze-dried pharmaceutical product and method of manufacturing a sealed vessel accommodating a freeze-dried pharmaceutical product
US5827541A (en) Process for preparing solid pharmaceutical dosage forms of hydrophobic substances
CA1083042A (en) Pharmaceutical dosage forms for oral administration
US20060212020A1 (en) Sample collection system with caspase inhibitor
CZ20022972A3 (cs) Způsob extrakce
CN103200922A (zh) 用于密封容器的装置及制造密封容器的方法
AU2003245635A1 (en) Mixing vial
US20160320415A1 (en) Fast reconstituting reagent pellets
US20110155620A1 (en) Rapid reconstitution for lyophilized-pharmaceutical suspensions
CN1894026B (zh) 用于活性药剂的低温制粒和贮藏的方法
US20020121454A1 (en) Combined pill and water container
CN101018798B (zh) 难固结结晶麦芽糖醇粉末及其制备方法
WO2000036353A1 (en) Method for drying a material in a container having one or more pierced holes
CN112789472B (zh) 冻干容器
WO1999025629A1 (en) Multicompartment container for combination products
JPH08280807A (ja) 用時溶解スプレー容器及び該容器を用いた用時溶解スプレー
US20050070873A1 (en) Constituent delivery system
IT201900009999A1 (it) Dispositivo di tappatura di un flacone atto alla conservazione di una sostanza confezionata in una cialda e contenuta in una cavità di esso.
WO2018104814A1 (en) Kit for the controlled combination of active ingredients
TH52862A (da)

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20120912