CN102657809A - Medicament for treating oligohydramnios - Google Patents
Medicament for treating oligohydramnios Download PDFInfo
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Abstract
The invention discloses a medicament for treating oligohydramnios so as to solve the treatment problem of oligohydramnios. The medicament is characterized by being prepared by various traditional Chinese medicines as follows in parts by weight: 15-20 parts of hairy asiabell root, 15-20 parts of ladybell root, 10-15 parts of prepared rehmannia rhizome, 12-18 parts of white paeony root, 10-15 parts of parched white atractylodes rhizome, 4-8 parts of honey-fried licorice root, 12-18 parts of dwarf lilyturf tuber, 20-40 parts of Chinese dodder seed, 20-30 parts of Chinese taxillus twig, 12-18 parts of manyflower solomonseal rhizome, 10-15 parts of eucommia bark, 10-15 parts of teasel, 12-18 parts of Chinese angelica, 10-15 parts of tortoise shell, 10-15 parts of poria cocos, 10-15 parts of medlar, 6-12 parts of perilla stem, 10-15 parts of donkey-hide gelatin, 20-40 parts of reed rhizome and 4-6 parts of fructus amomi. Clinical experiments prove that the medicament has the characteristics of good curative effect and higher safety for treating the oligohydramnios and is worthy of clinical application and popularization.
Description
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to treat the medicine of oligohydramnios.
Background technology
Oligohydramnios (oligohydramnios) is the commonly encountered diseases and the frequently-occurring disease of obstetrics, is meant that the amniotic fluid amount lacks, and is lower than normal level.Pregnancy early, mid-term amniotic fluid content comparatively stable, late trimester of pregnancy, individual variation was very big, to be less than 300ml be oligohydramnios to the amniotic fluid amount during full-term pregnancy.Early, the oligohydramnios of midtrimester of pregnancy is many comes to an end with miscarriage, and the oligohydramnios of finding clinically is many after pregnant 28 weeks, is a kind of gravidic complication, and many and high risk pregnancy, high-risk youngster and human fetal urinary road deformity have substantial connection.Think that in the past the incidence rate of oligohydramnios is about 0.1%, but in recent years owing to the ultransonic extensive use of Type B, the recall rate of oligohydramnios is 0.5%～4.0%, also has report to be about 8% recently, recall rate increases to some extent.Modern medicine thinks that oligohydramnios is the signal of interest of FD; Enclose living youngster's M & M and obviously raise, compare with normal pregnancy, the living youngster's mortality rate that encloses of slight oligohydramnios increases 13 times; And the severe oligohydramnios increases 47 times, and has become present caesarean delivered one of the main reasons.Doctor trained in Western medicine except that timely termination of pregnancy, also can adopt through the amniotic cavity infusion treatment, but clinical expansion is difficult to oligohydramnios Therapeutic Method limitation at present.
Summary of the invention
Technical assignment of the present invention is the deficiency to above prior art, and the medicine of the sure treatment oligohydramnios of a kind of curative effect is provided.
The technical scheme that the present invention solves its technical problem is: a kind of medicine of treating oligohydramnios, it is characterized in that processing by plurality of Chinese, and its weight proportion is: 15 ~ 20 parts of Radix Codonopsis, 15 ~ 20 parts of Radix Adenophoraes, 10 ~ 15 parts in Radix Rehmanniae Preparata; 12 ~ 18 parts of the Radix Paeoniae Albas, 10 ~ 15 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 4 ~ 8 parts of Radix Glycyrrhizae Preparatas, 12 ~ 18 parts of Radix Ophiopogonis, 20 ~ 40 parts of Semen Cuscutae; 20 ~ 30 parts of Herba Taxillis, 12 ~ 18 parts of Rhizoma Polygonatis, 10 ~ 15 parts of the Cortexs Eucommiae, 10 ~ 15 parts of Radix Dipsacis; 12 ~ 18 parts of Radix Angelicae Sinensis, 10 ~ 15 parts of Carapax Et Plastrum Testudiniss, 10 ~ 15 parts in Poria, 10 ~ 15 parts of Fructus Lycii; 6 ~ 12 parts of Caulis Perillaes, 10 ~ 15 parts in Colla Corii Asini, 20 ~ 40 parts of Rhizoma Phragmitiss, 4 ~ 6 parts of Fructus Amomis.
The weight proportion of its optimization is: 18 parts of Radix Codonopsis, 18 parts of Radix Adenophoraes, 12 parts in Radix Rehmanniae Preparata, 15 parts of the Radix Paeoniae Albas, 12 parts of Rhizoma Atractylodis Macrocephalae (parched)s; 6 parts of Radix Glycyrrhizae Preparatas, 15 parts of Radix Ophiopogonis, 30 parts of Semen Cuscutae, 24 parts of Herba Taxillis, 15 parts of Rhizoma Polygonatis; 12 parts of the Cortexs Eucommiae, 12 parts of Radix Dipsacis, 15 parts of Radix Angelicae Sinensis, 12 parts of Carapax Et Plastrum Testudiniss, 12 parts in Poria; 12 parts of Fructus Lycii, 9 parts of Caulis Perillaes, 12 parts in Colla Corii Asini, 30 parts of Rhizoma Phragmitiss, 5 parts of Fructus Amomis.
Also contain alizarin 10 ~ 15 parts of sea in its optimization of C.
Wherein said:
Radix Codonopsis is the dry root of campanulaceae plant Radix Codonopsis Codonopsis pilosula (Franch.) Nannf., plain flower Radix Codonopsis Codonopsis pilosula Nannf. var. modesta (Nannf.) L. T. Shen or radix codonpsis tangshen Codonopsis tangshen Oliv..Nature and flavor are sweet, and are flat.Return spleen, lung meridian.But the merit invigorating the spleen and replenishing QI, the spleen invigorating lung benefiting.
Radix Adenophorae is the dry root of campanulaceae plant adenophora tetraphylla Adenophora tetraphylla (Thunb.) Fisch. or Radix Adenophorae (Radix Glehniae) Adenophora stricta Miq..Nature and flavor are sweet, are slightly cold.Attach to the lung and stomach meridians.But the merit nourishing YIN and clearing away lung-heat is reduced phlegm, QI invigorating.
Radix Rehmanniae Preparata is concocted through processing for the tuber of scrophulariaceae rehmannia glutinosa plant Rehmannia glutinosa Libosch. and to be formed.Sweet in the mouth; Warm in nature.Return liver, kidney channel.Merit can be enriched blood moist; The benefit essence is filled out marrow.
The Radix Paeoniae Alba is the dry root of ranunculaceae plant Radix Paeoniae Paeonia lactiflora Pall..Nature and flavor are bitter, sour, are slightly cold.Return liver, spleen channel.But the pain relieving of merit suppressing the hyperactive liver, nourishing blood for regulating menstruation, astringing YIN to stop sweating.
Rhizoma Atractylodis Macrocephalae (parched) is the dry rhizome of feverfew Rhizoma Atractylodis Macrocephalae Atractylodes macrocephala Koidz..The processed with honey wheat bran is sprinkled in the heat pot, adds Rhizoma Atractylodis Macrocephalae sheet when waiting to smolder, fry to coke yellow, effusion burnt odor gas, take out, sieve removes the processed with honey wheat bran.Nature and flavor are bitter, sweet, temperature.Return spleen, stomach warp.But the merit invigorating the spleen and benefiting QI, the dampness diuretic, hidroschesis, antiabortive.
Radix Glycyrrhizae Preparata is concocted through processing for the dry root of glycyrrhizic legume Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L. Glycyrrhiza glabra L. and to be formed.Nature and flavor are sweet, and are flat.GUIXIN, lung, spleen, stomach warp.But the merit invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
Radix Ophiopogonis, be the dried root of liliaceous plant Radix Ophiopogonis (dwarf lilyturf) Ophiopogon japonicus (Thunb.) Ker-Gawl..Nature and flavor are sweet, and little hardship is slightly cold.GUIXIN, lung, stomach warp.But the merit YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.
Semen Cuscutae is the dry mature seed of convolvulus cuscuta plant Cuscuta chinensis Lam..Nature and flavor are sweet, temperature.Return the liver,kidney,spleen warp.But the merit nourishing the liver and kidney, the controlling nocturnal emission with astringent drugs reducing urination, antiabortive, make eye bright antidiarrheal.
Herba Taxilli is the dry stem and branch with leaf of Loranthaceae plant Herba Taxilli Taxillus chinensis (DC.) Danser.Nature and flavor are bitter, sweet, and are flat.Return liver, kidney channel.But the merit invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive unit.
Rhizoma Polygonati is the dry rhizome of liliaceous plant Yunnan Rhizoma Polygonati Polygonatum kingianum Coll.et Hemsl., Rhizoma Polygonati Polygonatum sibiricum Red. or Polygonatum cyrtonema Hua Polygonatum cyrtonema Hua.Nature and flavor are sweet, and are flat.Return spleen, lung, kidney channel.But the merit boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.
The Cortex Eucommiae is the dry bark of Eucommiaceae plant Cortex Eucommiae Eucommia ulmoides Oliv..Nature and flavor are sweet, temperature.Return liver, kidney channel.But the merit invigorating the liver and kidney, bone and muscle strengthening, antiabortive.
Radix Dipsaci is the dry root of Dipsacaceae herbaceos perennial Radix Dipsaci Himalayan Teasel Root.Bitter in the mouth is hot; Slightly warm in nature.Return liver, kidney channel.But merit invigorating the liver and kidney; Bone and muscle strengthening; Blood circulation regulating; Continuous folding is hindered; End metrorrhagia.
Radix Angelicae Sinensis is the dry root of umbelliferae angelica Angelica sinensis (Oliv.) Diels.Nature and flavor are sweet, hot, temperature.Return liver, the heart, spleen channel.Merit can be enriched blood and invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.
Carapax Et Plastrum Testudinis is carapace and the sternite of Testudinidae animal Testudinis Chinemys reevesii (Gray).Nature and flavor are salty, sweet, are slightly cold.Return liver, kidney, heart channel.But the merit nourishing YIN for suppressing the hyperactive YANG, kidney tonifying bone strengthening, the reinforcing the heart of nourishing blood.
Poria is the white part of Polyporaceae fungus Poria Poriacocos (Schw.) Wolf sclerotium.Nature and flavor are sweet, light, and are flat.GUIXIN, lung, spleen, kidney channel.But the merit promoting diuresis to eliminate damp pathogen, spleen invigorating is reduced phlegm, mind tranquilizing and the heart calming.
Fructus Lycii is the dry mature fruit of plant of Solanaceae lycium barbarum Lycium barbarum L..Nature and flavor are sweet, and are flat.Return liver, kidney channel.But the merit nourishing the liver and kidney, replenishing vital essence to improve eyesight.
Caulis Perillae is the dry stem of labiate Folium Perillae Perilla frutescens (L.) Britt..Nature and flavor are hot, temperature.Return lung, spleen channel.But the merit regulating the flow of QI to ease the stomach, pain relieving, antiabortive.
Colla Corii Asini, for donkey skin through decocting, concentrate the solid gum of processing.Nature and flavor are sweet, and are flat.Return lung, liver, kidney channel.The merit YIN nourishing of can enriching blood is moisturized, hemostasis.
Rhizoma Phragmitis is grass phragmites communis rhizome.Nature and flavor are sweet, and are cold.Go into lung, stomach warp.But merit lung heat clearing gastric heat, promoting the production of body fluid to quench thirst.
Fructus Amomi is the mature fruit of Zingiberaceae herbaceous plant Fructus Amomi AmonumvillqsumLouv. or the SEMEN AMOMI LONGILIGULA A.longiligulare T.L.Wu or the sand A.xanthioidesWall. that contracts.Nature and flavor are hot, temperature.Return spleen, stomach, kidney channel.But merit removing dampness circulation of qi promoting, warming middle-JIAO to stop diarrhea, antiabortive.
Hai Qian is the frond of Sargassaceae plant Alga Sgrgassi Enerves Sargassum enerve C.Ag., Heng Shi Alga Sgrgassi Enerves Sargassum henslowianum C.Ag., Mus tail algae Sargassum thunbergii (Mert.) O.Kuntze or Sargassum phyllocystum Tseng et Lu,Sargassum horneri (Turn.) C. Ag. (Fucus horneri (Turn.)C.Ag.,Spongocarpus horneri Kutz.) argassum horneri (Turn.) C. Ag.Nature and flavor are salty; Cold.Return liver; Stomach; Kidney channel.But merit hard masses softening and resolving; Removing heat-phlegm.
Composition principle: oligohydramnios does not have special argumentation in successive dynasties traditional Chinese medical science works.It is mentioned in the same breath in many and diapause, says like " Jing Yue's complete work married woman rule ": " many taste of married woman patient has it, and thin then change source, granary is lost and dashed and appoint thoroughly also." " all medicine source marquis opinion " point out " tire born of the same parents, the nourishing of blood.If vim and vigour are deficient, the dirty cold person of born of the same parents, tire is the dry Fu Buchang that withers of nebula then.Its shape all can not rotate at tire, also can not give birth to though life is full, be its marquis also.And tire withers dryly interior, and how dead its tire is." what say is exactly oligohydramnios, postterm pregnancy and the fetal in utero growth restriction of doctor trained in Western medicine, theoretical consistent with doctor trained in Western medicine.The traditional Chinese medical science thinks, the basic pathogenesis of oligohydramnios be insufficiency of vital energy and blood the bringing about the spread of body fluid is not enough with flourish its tire, amniotic fluid can not generate.But inventor's clinical practice is found; Oligohydramnios is clearly relevant with the spleen kidney deficiency, and is mingled with the performance that gas is not all right, blood is not transported, wet and do not change again, echoes with the modern medicine microcosmic syndrome differentiation: see placental calcification, aging under ultrasonic more; The Placenta Hominis pathologic finding is it is thus clear that have obvious extensive calcification and pale infarct; Microscopically sees that the extensive fibrinoid degeneration of fine hair is downright bad, and syncytial cell tuberosity work increases, fine hair blood vessel cellulose appearance thing deposition.So side of the present invention gets Radix Codonopsis, Poria, Radix Glycyrrhizae Preparata, Rhizoma Atractylodis Macrocephalae (parched) invigorating the spleen and benefiting QI; Support Radix Adenophorae, Radix Ophiopogonis the lung stomach-Yin, Rhizoma Polygonati, Radix Rehmanniae Preparata, Carapax Et Plastrum Testudinis are supported kidney yin; Fructus Lycii, Semen Cuscutae, the Cortex Eucommiae, Herba Taxilli, Radix Dipsaci nourishing the liver and kidney; Radix Angelicae Sinensis, the Radix Paeoniae Alba, Colla Corii Asini, Carapax Et Plastrum Testudinis all have the merit of enriching blood; Caulis Perillae regulating the flow of QI to ease the stomach and be so incensed that with row, Chinese angelica blood supplementing is invigorated blood circulation and blood is able to transport it, Fructus Amomi removing dampness circulation of qi promoting and wet being able to it, Rhizoma Phragmitis lung heat clearing gastric heat and heat is able to loose it, and Rhizoma Atractylodis Macrocephalae (parched), Semen Cuscutae, Herba Taxilli, the Cortex Eucommiae, Fructus Amomi all have antiabortive merit.
Like main disease is that pregnant middle and advanced stage abdomen shape and palace body are slightly little, and oligohydramnios is found in ultrasonic examination, and sees that obvious Placenta Hominis echo is uneven or be dispersed in strong echo speckle person, then has the sign of stasis of blood resistance vessels of the uterus, should get extra large alizarin hard masses softening and resolving.Modern pharmacological research shows: the main component laminarin sulfate of Hai Qian can make rabbit amniotic fluid property microcirculation disturbance alleviate; Flow velocity is accelerated, and fluidised form is improved, and erythrocyte aggregation reduces; Cruor time extending; The Hai Qianshui extract can make whole blood of the hemorheology sexual abnormality rabbit due to the high molecular dextran and blood plasma viscosity reduce, and erythrocyte electrophoresis speeds up, and microcirculation improves.
The specific embodiment
Below in conjunction with practical situation, specific embodiments of the invention elaborates.
Embodiment 1, the crude drug weight proportion: Radix Codonopsis 15g, Radix Adenophorae 15g, Radix Rehmanniae Preparata 10g, Radix Paeoniae Alba 12g, Rhizoma Atractylodis Macrocephalae (parched) 10g; Radix Glycyrrhizae Preparata 4g, Radix Ophiopogonis 12g, Semen Cuscutae 20g, Herba Taxilli 20g, Rhizoma Polygonati 12g; Cortex Eucommiae 10g, Radix Dipsaci 10g, Radix Angelicae Sinensis 12g, Carapax Et Plastrum Testudinis 10g, Poria 10g; Fructus Lycii 10g, Caulis Perillae 6g, Colla Corii Asini 10g, Rhizoma Phragmitis 20g, Fructus Amomi 4g.
Embodiment 2, the crude drug weight proportion: Radix Codonopsis 20g, Radix Adenophorae 20g, Radix Rehmanniae Preparata 15g, Radix Paeoniae Alba 18g, Rhizoma Atractylodis Macrocephalae (parched) 15g; Radix Glycyrrhizae Preparata 8g, Radix Ophiopogonis 18g, Semen Cuscutae 40g, Herba Taxilli 30g, Rhizoma Polygonati 18g; Cortex Eucommiae 15g, Radix Dipsaci 15g, Radix Angelicae Sinensis 18g, Carapax Et Plastrum Testudinis 15g, Poria 15g; Fructus Lycii 15g, Caulis Perillae 12g, Colla Corii Asini 15g, Rhizoma Phragmitis 40g, Fructus Amomi 6g.
Embodiment 3, the crude drug weight proportion: Radix Codonopsis 18g, Radix Adenophorae 18g, Radix Rehmanniae Preparata 12g, Radix Paeoniae Alba 15g, Rhizoma Atractylodis Macrocephalae (parched) 12g; Radix Glycyrrhizae Preparata 6g, Radix Ophiopogonis 15g, Semen Cuscutae 30g, Herba Taxilli 24g, Rhizoma Polygonati 15g; Cortex Eucommiae 12g, Radix Dipsaci 12g, Radix Angelicae Sinensis 15g, Carapax Et Plastrum Testudinis 12g, Poria 12g; Fructus Lycii 12g, Caulis Perillae 9g, Colla Corii Asini 12g, Rhizoma Phragmitis 30g, Fructus Amomi 5g.
Embodiment 4, the crude drug weight proportion: Radix Codonopsis 15g, Radix Adenophorae 15g, Radix Rehmanniae Preparata 10g, Radix Paeoniae Alba 12g, Rhizoma Atractylodis Macrocephalae (parched) 10g; Radix Glycyrrhizae Preparata 4g, Radix Ophiopogonis 12g, Semen Cuscutae 20g, Herba Taxilli 20g, Rhizoma Polygonati 12g, Cortex Eucommiae 10g; Radix Dipsaci 10g, Radix Angelicae Sinensis 12g, Carapax Et Plastrum Testudinis 10g, Poria 10g, Fructus Lycii 10g; Caulis Perillae 6g, Colla Corii Asini 10g, Rhizoma Phragmitis 20g, Fructus Amomi 4g, extra large alizarin 15g.
Embodiment 5, the crude drug weight proportion: Radix Codonopsis 20g, Radix Adenophorae 20g, Radix Rehmanniae Preparata 15g, Radix Paeoniae Alba 18g, Rhizoma Atractylodis Macrocephalae (parched) 15g; Radix Glycyrrhizae Preparata 8g, Radix Ophiopogonis 18g, Semen Cuscutae 40g, Herba Taxilli 30g, Rhizoma Polygonati 18g, Cortex Eucommiae 15g; Radix Dipsaci 15g, Radix Angelicae Sinensis 18g, Carapax Et Plastrum Testudinis 15g, Poria 15g, Fructus Lycii 15g; Caulis Perillae 12g, Colla Corii Asini 15g, Rhizoma Phragmitis 40g, Fructus Amomi 6g, extra large alizarin 10g.
Embodiment 6, the crude drug weight proportion: Radix Codonopsis 18g, Radix Adenophorae 18g, Radix Rehmanniae Preparata 12g, Radix Paeoniae Alba 15g, Rhizoma Atractylodis Macrocephalae (parched) 12g; Radix Glycyrrhizae Preparata 6g, Radix Ophiopogonis 15g, Semen Cuscutae 30g, Herba Taxilli 24g, Rhizoma Polygonati 15g, Cortex Eucommiae 12g; Radix Dipsaci 12g, Radix Angelicae Sinensis 15g, Carapax Et Plastrum Testudinis 12g, Poria 12g, Fructus Lycii 12g; Caulis Perillae 9g, Colla Corii Asini 12g, Rhizoma Phragmitis 30g, Fructus Amomi 5g, extra large alizarin 12g.
The Chinese medicine of the embodiment of the invention 1 ~ 3 can be prepared from by following method: get decocting that Carapax Et Plastrum Testudinis adds 10 times of volumes and boil to add after 30 minutes and get Radix Codonopsis, Radix Adenophorae, Radix Rehmanniae Preparata, the Radix Paeoniae Alba, Rhizoma Atractylodis Macrocephalae (parched), Radix Glycyrrhizae Preparata, Radix Ophiopogonis, Semen Cuscutae, Herba Taxilli, Rhizoma Polygonati, the Cortex Eucommiae, Radix Dipsaci, Radix Angelicae Sinensis, Poria, Fructus Lycii, Rhizoma Phragmitis and decocted 20 minutes; Add Caulis Perillae, Fructus Amomi continuation decoction 10 minutes; Cross leaching filtrating; In medicinal residues, adding the isopyknic decocting of filtrating again boiled 20 minutes; Cross leaching filtrating, twice filtrating merges the back and adds the Colla Corii Asini molten.
The Chinese medicine of the embodiment of the invention 4 ~ 6 can be prepared from by following method: get decocting that Carapax Et Plastrum Testudinis adds 10 times of volumes and boil to add after 30 minutes and get Radix Codonopsis, Radix Adenophorae, Radix Rehmanniae Preparata, the Radix Paeoniae Alba, Rhizoma Atractylodis Macrocephalae (parched), Radix Glycyrrhizae Preparata, Radix Ophiopogonis, Semen Cuscutae, Herba Taxilli, Rhizoma Polygonati, the Cortex Eucommiae, Radix Dipsaci, Radix Angelicae Sinensis, Poria, Fructus Lycii, Rhizoma Phragmitis, Hai Qian and decocted 20 minutes; Add Caulis Perillae, Fructus Amomi continuation decoction 10 minutes; Cross leaching filtrating; In medicinal residues, adding the isopyknic decocting of filtrating again boiled 20 minutes; Cross leaching filtrating, twice filtrating merges the back and adds the Colla Corii Asini molten.
Effective combination of said medicine is coordinated mutually, effectively reach the purpose of treatment oligohydramnios, and side effect is less.The above results is that clinical data proves that fully interrelated data is following.
1 object and method
1.1 being in January, 2011 ~ 2011, object institute is in hospital and outpatient service oligohydramnios 58 examples at me year JIUYUE; All detect through doppler ultrasound; < 8.0ml is as the oligohydramnios marginal value for index of amniotic fluid (AFI); AFI≤5.0ml is the oligohydramnios absolute value, and the equal nutriture of each case is good, and blood glucose, blood fat and hepatic and renal function are all in normal range.Patient age 22 ~ 40 years old, 27.53 ± 6.13 years old mean age.Primipara's 36 examples, multipara's 22 examples, gestation merge fetal in utero growth restriction 6 examples, cord around neck 10 examples, preeclampsia 5 examples, breech presentation 3 examples, pregnant week < 37 all 3 examples, 37 ~ 39 all 54 examples, minimum pregnant all 19 all 1 examples.
1.2 method
1.2.1 the research method embodiment of the invention 3 Chinese medicines are the treatment of basis side, see that like ultrasonic examination obvious Placenta Hominis echo is uneven or be dispersed in strong echo speckle person, reelect embodiment 6 treatments by Chinese herbs, potion divided sooner or later and took for twice every day.7 days is a course of treatment, and it is color ultra to treat after 7 days check, with AFI>8.0ml serve as treatment effectively, measure AFI later on weekly to childbirth, advise its polydipsia water, the fetal movement of testing oneself.
1.2.2 all carry out monitorings such as blood, urine, stool routine, liver, renal function, electrocardiogram before and after the safety evaluatio medication.
2 results
2.1 AFI value: 58 routine oligohydramnios patients are after treatment by Chinese herbs of the present invention, and the AFI value all has rising in various degree, and < 8.0ml is increased to 10 ~ 11.7ml to AFI, and total effective rate is 84.48% before the 49 example treatments; 9 examples through treatment after 7 days AFI still 8.0ml, pregnant week reached for 39 weeks, row cuts open the palace and produce to finish gives birth to, neonate is born in order.
2.2 untoward reaction: patient's vital sign (blood pressure, heart rate, body temperature, breathing), physical examination, blood biochemical analysis, electrocardiogram and routine urinalysis Non Apparent Abnormality during treating.
3. conclusion
The prompting of this result of study, the present invention treats oligohydramnios and has good effect and the higher characteristics of safety, is worth clinical practice, popularization.
Claims (3)
1. a medicine of treating oligohydramnios is characterized in that being processed by plurality of Chinese, and its weight proportion is: 15 ~ 20 parts of Radix Codonopsis, 15 ~ 20 parts of Radix Adenophoraes, 10 ~ 15 parts in Radix Rehmanniae Preparata; 12 ~ 18 parts of the Radix Paeoniae Albas, 10 ~ 15 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 4 ~ 8 parts of Radix Glycyrrhizae Preparatas, 12 ~ 18 parts of Radix Ophiopogonis, 20 ~ 40 parts of Semen Cuscutae; 20 ~ 30 parts of Herba Taxillis, 12 ~ 18 parts of Rhizoma Polygonatis, 10 ~ 15 parts of the Cortexs Eucommiae, 10 ~ 15 parts of Radix Dipsacis; 12 ~ 18 parts of Radix Angelicae Sinensis, 10 ~ 15 parts of Carapax Et Plastrum Testudiniss, 10 ~ 15 parts in Poria, 10 ~ 15 parts of Fructus Lycii; 6 ~ 12 parts of Caulis Perillaes, 10 ~ 15 parts in Colla Corii Asini, 20 ~ 40 parts of Rhizoma Phragmitiss, 4 ~ 6 parts of Fructus Amomis.
2. a kind of medicine of treating oligohydramnios according to claim 1 is characterized in that its weight proportion is: 18 parts of Radix Codonopsis, 18 parts of Radix Adenophoraes, 12 parts in Radix Rehmanniae Preparata, 15 parts of the Radix Paeoniae Albas; 12 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 6 parts of Radix Glycyrrhizae Preparatas, 15 parts of Radix Ophiopogonis, 30 parts of Semen Cuscutae, 24 parts of Herba Taxillis, 15 parts of Rhizoma Polygonatis; 12 parts of the Cortexs Eucommiae, 12 parts of Radix Dipsacis, 15 parts of Radix Angelicae Sinensis, 12 parts of Carapax Et Plastrum Testudiniss, 12 parts in Poria; 12 parts of Fructus Lycii, 9 parts of Caulis Perillaes, 12 parts in Colla Corii Asini, 30 parts of Rhizoma Phragmitiss, 5 parts of Fructus Amomis.
3. a kind of medicine of treating oligohydramnios according to claim 1 is characterized in that, also comprises alizarin 10 ~ 15 parts of sea.
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| CN2012101639329A CN102657809B (en) | 2012-05-24 | 2012-05-24 | Medicament for treating oligohydramnios |
| CN201310677096.0A CN103599465B (en) | 2012-05-24 | 2012-05-24 | A kind of medicine for the treatment of stasis blocking vessels of the uterus type oligohydramnios |
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| CN2012101639329A CN102657809B (en) | 2012-05-24 | 2012-05-24 | Medicament for treating oligohydramnios |
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| CN201310677096.0A Expired - Fee Related CN103599465B (en) | 2012-05-24 | 2012-05-24 | A kind of medicine for the treatment of stasis blocking vessels of the uterus type oligohydramnios |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102885976A (en) * | 2012-11-06 | 2013-01-23 | 周兴雪 | Traditional Chinese medicine for treating oligoamnios and preparation method thereof |
| CN103877412A (en) * | 2014-03-18 | 2014-06-25 | 于法周 | Traditional Chinese medicine for treating oligohydramnion in middle and late stages of pregnancy |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104721544A (en) * | 2015-02-16 | 2015-06-24 | 刘辉 | Medicine for treating qi and blood deficiency type oligohydramnios of pregnant women and preparation method of medicine |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1985976A (en) * | 2006-12-20 | 2007-06-27 | 北京润德康医药技术有限公司 | Abortion preventing Yimu preparation and its new preparing process |
| CN101279073A (en) * | 2008-04-10 | 2008-10-08 | 北京中泰天和科技有限公司 | Chinese medicinal composition for curing habitual abortion and method of preparing the same |
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2012
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1985976A (en) * | 2006-12-20 | 2007-06-27 | 北京润德康医药技术有限公司 | Abortion preventing Yimu preparation and its new preparing process |
| CN101279073A (en) * | 2008-04-10 | 2008-10-08 | 北京中泰天和科技有限公司 | Chinese medicinal composition for curing habitual abortion and method of preparing the same |
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| 李新平: "健脾补肾固胎治疗先兆流产46例", 《时珍国医国药》 * |
| 郭兰春: "中药配合复方丹参治疗妊娠晚期羊水过少37例分析", 《中国误诊学杂志》 * |
| 马红平等: "口服中药与复方丹参注射液治疗羊水过少的临床观察", 《中国医疗前沿》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102885976A (en) * | 2012-11-06 | 2013-01-23 | 周兴雪 | Traditional Chinese medicine for treating oligoamnios and preparation method thereof |
| CN103877412A (en) * | 2014-03-18 | 2014-06-25 | 于法周 | Traditional Chinese medicine for treating oligohydramnion in middle and late stages of pregnancy |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103599465B (en) | 2015-11-04 |
| CN103599465A (en) | 2014-02-26 |
| CN102657809B (en) | 2013-12-18 |
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