CN102614548A - Stem cell biological preparation for cosmetic surgery treatment - Google Patents
Stem cell biological preparation for cosmetic surgery treatment Download PDFInfo
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- CN102614548A CN102614548A CN2012101214210A CN201210121421A CN102614548A CN 102614548 A CN102614548 A CN 102614548A CN 2012101214210 A CN2012101214210 A CN 2012101214210A CN 201210121421 A CN201210121421 A CN 201210121421A CN 102614548 A CN102614548 A CN 102614548A
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Abstract
The invention discloses application of allogeneic mesenchymal stem cells to cosmetic surgery treatment and a stem cell biological preparation for cosmetic surgery treatment. The stem cell biological preparation consists of physiological saline suspension of allogeneic mesenchymal stem cells and hyaluronic acid, wherein the volume ratio of the suspension to the hyaluronic acid is equal to 1-2:1-2; and every one mL of suspension contains 5*10<7>-10*10<7> cells. According to the stem cell biological preparation, the treatment of cosmetic surgery by a stem cell technology is finished by using a regenerative medical technology through formula design; the operation method is simple and safe; the stem cell biological preparation is easy for a patient to accept, is time-saving and quick in response and has an obvious curative effect; a permanent cosmetic effect can be obtained; and thus, the development of the stem cell disease treatment technology can be favorably promoted.
Description
Technical field
The present invention relates to medical science shaping and beauty technical field, relate in particular to a kind of be used to treat skin histology damage and damaged biological preparation.
Background technology
For skin histology damage and damaged shaping and beauty treatment, mainly be that the method that adopts soft tissue to fill is repaired.At present, being used for the packing material of soft tissue shaping, is synthetic material mostly, like white beeswax, silicones, gel implant etc.And synthetic material is divided into permanent and provisional material, and the permanent material and the tissue compatibility are poor, thereby can become foreign body in vivo, and has problems such as sclerosis, chronic inflammatory disease, side effect be big; The provisional material persistent period is short, generally continues about 1 year promptly by the body absorption, therefore only produces effect in short-term.For this reason, also the method for autologous fat transplantation has been used in research clinically, as packing material, but exists the low problem of survival rate with the autologous fat tissue.In recent years; The development that learns a skill along with organizational project; People have also studied through cultured and amplified in vitro autologous tissue cell and implanted in the body to realize the method for repair and reconstruction; But make slow progress, exist long, problem such as curative effect is not remarkable of treatment time, and still not have definite combination formula at present.
Mescenchymal stem cell is one type and derives from growth early stage mesoderm and ectodermic pluripotent stem cell; Mainly be present between connective tissue and organ in the matter; Have multidirectional differentiation potential, hemopoietic support and promote characteristics such as stem cell implantation, immunoregulation and self replication; And the allosome mescenchymal stem cell has been proved and can have treated manyly clinically like difficult diseases such as end-age cirrhosis, diabetic complication, myocardial infarction, autoimmune diseasees, and is superior to from the body mescenchymal stem cell.At present, find as yet to have the allosome mescenchymal stem cell is used for the shaping and beauty aspect with damage of treatment skin histology and damaged clinical report.
Summary of the invention
The objective of the invention is to overcome the deficiency of prior art; Providing a kind of is the master, is applicable to the biological preparation of shaping and beauty with the allosome mescenchymal stem cell; To realize the breakthrough of stem cell disease treatment technology, effectively improve the therapeutic effect of stem cell shaping and beauty technology.
The object of the invention is achieved through following technical scheme:
The present invention provides the application of allosome mescenchymal stem cell in the shaping and beauty treatment.
A kind of stem cell biological preparation that is used for the shaping and beauty treatment provided by the invention; Normal saline suspension, hyaluronic acid by the allosome mescenchymal stem cell are formed; Each volume ratio of forming is a suspension: hyaluronic acid=1～2: 1～2, and said suspension contains cell 5 * 10
7～10 * 10
7Individual/mL.Preferred version is that said each volume ratio of forming is a suspension: hyaluronic acid=1: 1, said suspension contains cell 5 * 10
7Individual/mL.
Further, the allosome mescenchymal stem cell that biological preparation of the present invention adopted derives from umbilical cord, Cord blood, Placenta Hominis, amniotic membrane, bone marrow.
The present invention has following beneficial effect:
(1) the present invention adopts regeneration medicine technology, through recipe design, accomplishes the treatment of stem cells technology shaping and beauty, has realized the breakthrough of stem cell disease treatment technology.Simple, the safety of operational approach, the patient is easy to accept, and save time, produce effects is fast, avoided the loss of cytoactive, can obtain nonvolatil shaping, evident in efficacy and longer duration.
(2) the present invention utilizes hyaluronic acid as biological support, and mescenchymal stem cell is mixed in hyaluronic acid, is filled into therapentic part.The stem cell tissue that regeneration makes new advances at the biological support place, biological support is metabolism gradually then, excretes.Because stem cell grows the tissue of self damaged with the filling position, so can not cause systemic damage, and effect is nonvolatil.
(3) the present invention adopts the allosome mescenchymal stem cell to carry out the shaping and beauty treatment, and it promotes the regenerated effect of body, is better than the stem cell from body, and does not have rejection, and is evident in efficacy.
(4) allosome mescenchymal stem cell source is sufficient, can use stock's cell and obtains timely treatment, needs to wait for problems such as (one month even longer time), treatment time length, scarce capacity thereby overcome the cultivation autologous stem cells.
Description of drawings
Below in conjunction with embodiment and accompanying drawing the present invention is described in further detail.
Fig. 1 is one of an embodiment of the invention treatment case damaged preceding photo;
Fig. 2 is the photo after the treatment of Fig. 1 example;
Fig. 3 is two damaged preceding photos of embodiment of the invention treatment case;
Fig. 4 is the photo after the treatment of Fig. 3 example;
Fig. 5 is three damaged preceding photos of embodiment of the invention treatment case;
Fig. 6 is the photo after the treatment of Fig. 5 example.
The specific embodiment
One, the preparation of biological preparation
Adopt the allosome mescenchymal stem cell, derive from the umbilical cord of healthy newborn, mix forming the 1mL suspension with normal saline, wherein contain cell 5 * 10
7Individual; Add hyaluronic acid 1mL mix homogeneously then.
Two, clinical experimental study
Be used to treat skin histology damage and damaged.
1, physical data
Case source: skin of face tissue defect 8 examples.Wherein, male patient's 5 examples, women's 3 examples, 28～65 years old age.
2, Therapeutic Method
Above-mentioned biological preparation is injected at the subcutaneous of defect, and injection 1～2mL fills defect and returns to normal appearance.Behind 6～December, the complete metabolism of hyaluronic acid disappears, and fills the tissue that position regeneration makes new advances, and has kept therapeutic effect.
3, curative effect situation
Like Fig. 1～shown in Figure 6, facial defect is recovered after treatment well, and is evident in efficacy.
Claims (4)
1. the application of allosome mescenchymal stem cell in the shaping and beauty treatment.
2. one kind is used for the stem cell biological preparation that shaping and beauty is treated; It is characterized in that: normal saline suspension, hyaluronic acid by the allosome mescenchymal stem cell are formed; Each volume ratio of forming is a suspension: hyaluronic acid=1～2: 1～2, and said suspension contains cell 5 * 10
7～10 * 10
7Individual/mL.
3. the stem cell biological preparation that is used for the shaping and beauty treatment according to claim 2 is characterized in that: said each volume ratio of forming is a suspension: hyaluronic acid=1: 1, said suspension contains cell 5 * 10
7Individual/mL.
4. according to claim 2 or the 3 described stem cell biological preparations that are used for the shaping and beauty treatment, it is characterized in that: said allosome mescenchymal stem cell derives from umbilical cord, Cord blood, Placenta Hominis, amniotic membrane, bone marrow.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012101214210A CN102614548A (en) | 2012-04-23 | 2012-04-23 | Stem cell biological preparation for cosmetic surgery treatment |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012101214210A CN102614548A (en) | 2012-04-23 | 2012-04-23 | Stem cell biological preparation for cosmetic surgery treatment |
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| CN102614548A true CN102614548A (en) | 2012-08-01 |
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| CN2012101214210A Pending CN102614548A (en) | 2012-04-23 | 2012-04-23 | Stem cell biological preparation for cosmetic surgery treatment |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104958319A (en) * | 2015-06-01 | 2015-10-07 | 成都清科生物科技有限公司 | Mesenchymal stem cell and cytokine preparation having treatment effects on premature ovarian failures and perimenopausal syndromes, and preparing method for preparation |
| CN106491647A (en) * | 2016-11-08 | 2017-03-15 | 华南生物医药研究院 | Application of the specific cell pharmaceutical intermixture in beauty and skin care |
| CN106491646A (en) * | 2016-11-08 | 2017-03-15 | 华南生物医药研究院 | New pharmaceutical composition of collagen secretion and application thereof can be stimulated |
| CN106562992A (en) * | 2016-11-08 | 2017-04-19 | 中国人民解放军军事医学科学院野战输血研究所 | New method for improving cell viability and promoting vascularization |
| CN106730015A (en) * | 2017-01-06 | 2017-05-31 | 朱凯林 | A kind of preparation for beauty and preparation method thereof |
| CN107583109A (en) * | 2017-09-22 | 2018-01-16 | 吉林大学 | A kind of corium deep layer filler and its preparation method and application |
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| US20060073178A1 (en) * | 2004-10-01 | 2006-04-06 | Giampapa Vincent C | Method and composition for restoration of age related tissue loss in the face or selected areas of the body |
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| TW201103572A (en) * | 2009-05-04 | 2011-02-01 | Neostem Inc | Method and composition for restoration of age-related tissue loss in the face or selected areas of the body |
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Patent Citations (3)
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| TW201103572A (en) * | 2009-05-04 | 2011-02-01 | Neostem Inc | Method and composition for restoration of age-related tissue loss in the face or selected areas of the body |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104958319A (en) * | 2015-06-01 | 2015-10-07 | 成都清科生物科技有限公司 | Mesenchymal stem cell and cytokine preparation having treatment effects on premature ovarian failures and perimenopausal syndromes, and preparing method for preparation |
| CN106491647A (en) * | 2016-11-08 | 2017-03-15 | 华南生物医药研究院 | Application of the specific cell pharmaceutical intermixture in beauty and skin care |
| CN106491646A (en) * | 2016-11-08 | 2017-03-15 | 华南生物医药研究院 | New pharmaceutical composition of collagen secretion and application thereof can be stimulated |
| CN106562992A (en) * | 2016-11-08 | 2017-04-19 | 中国人民解放军军事医学科学院野战输血研究所 | New method for improving cell viability and promoting vascularization |
| CN106730015A (en) * | 2017-01-06 | 2017-05-31 | 朱凯林 | A kind of preparation for beauty and preparation method thereof |
| CN107583109A (en) * | 2017-09-22 | 2018-01-16 | 吉林大学 | A kind of corium deep layer filler and its preparation method and application |
| CN107583109B (en) * | 2017-09-22 | 2020-09-25 | 吉林大学 | Dermal deep filler and preparation method and application thereof |
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Application publication date: 20120801 |