CN102614315A - Compound sleeping-improving capsule and preparation method thereof - Google Patents
Compound sleeping-improving capsule and preparation method thereof Download PDFInfo
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- CN102614315A CN102614315A CN201210121529XA CN201210121529A CN102614315A CN 102614315 A CN102614315 A CN 102614315A CN 201210121529X A CN201210121529X A CN 201210121529XA CN 201210121529 A CN201210121529 A CN 201210121529A CN 102614315 A CN102614315 A CN 102614315A
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Abstract
The invention discloses a compound sleeping-improving capsule and a preparation method thereof, which relate to a sleeping-improving product and a preparation method thereof and are used for solving the problems of dependence and side effect of most conventional sleeping-improving products. The compound sleeping-improving capsule is prepared from 45-55 parts by mass of an extract and 45-55 percent of pregelatinized starch, wherein the extract is prepared from 30-35 percent by mass of Chinese magnoliavine fruit, 20-25 percent by mass of acanthopanax root, 5-10 percent by mass of thinleaf milkwort root-bark, 10-15 percent by mass of spina date seed, 20-25 percent by mass of barbary wolfberry fruit and 5-10 percent of a Chinese date extract. The method comprises the following steps of: smashing raw materials such as Chinese magnoliavine fruit; extracting with a decoction method; concentrating an extracted substance into an extract; and preparing a capsule. The product contains various extracts, has the effect of improving sleeping, and contains rich nutrients. The product has the advantages of simple preparation process, low cost, good economic benefit and easiness for popularizing.
Description
Technical field
The present invention relates to a kind of product that improves sleep and preparation method thereof.
Background technology
Along with the development of society, people's life stress increases day by day, because the influence of various factors, sleep disorder is also more and more general with the phenomenon of not having enough sleep.
The most frequently used method of treatment sleep disorder is with chemosynthesis class sedative hypnotic at present, though have certain effect, takes for a long time and can produce certain dependency and side effect.Active component in the natural plants more and more receives extensive concern because its side effect is little, safe, it is wide to adapt to.In recent years domestic research worker conducts a research to the sedative-hypnotic effect of Chinese herbal medicine, finds that wherein many active component have the effect of tranquillizing and allaying excitement.
Summary of the invention
The invention discloses a kind of compound improvement sleep medicine and preparation method thereof, solved most of existing improvement sleep products and had the problem of dependency and side effect.This product contains multiple extract, except the effect of improving sleep is arranged, also contains multiple abundant nutrient.
The compound sleeping capsule that improves of the present invention is processed by 45 ~ 55% extract extractum and 45 ~ 55% pregelatinized Starch by mass percentage, and wherein extract extractum is processed by 30 ~ 35% Fructus Schisandrae Chinensis, 20 ~ 25% Radix Et Caulis Acanthopanacis Senticosis, 5 ~ 10% Radix Polygalaes, 10 ~ 15% Semen Ziziphi Spinosaes, 20 ~ 25% Fructus Lyciis and 5 ~ 10% Fructus Jujubae extracts by mass percentage.
Compound improvement sleep medicine of the present invention prepares according to the following steps:
1) prepares each main extract that divides: take by weighing Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi, Radix Polygalae, Semen Ziziphi Spinosae, Fructus Lycii, Fructus Jujubae fine powder; Behind its uniform mixing, add water with the ratio of solid-liquid ratio 1g:3 ~ 5ml, boiled 1 hour with slow fire; Filter then; Repeat to boil 3 times, merge extractive liquid, also is concentrated into paste, and it is subsequent use to get each main mixed extract that divides.
2) 45 ~ 55% extractum and 45 ~ 55% pregelatinized Starch mix homogeneously by mass percentage, and put into vacuum drying oven and dry, dried mixture is pulverized, sieve, incapsulate and promptly get the compound sleeping capsule goods that improve.
Contain effective ingredient such as lignanoids 29 ~ 40mg, organic acid 313 ~ 325mg, polysaccharide 465 ~ 475mg, Saponin class 826 ~ 835mg, flavonoid 514 ~ 525mg, flavonoid glycoside 61 ~ 70mg in the compound improvement sleep of the every 100g electuary.
Used raw material Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi, Radix Polygalae, Semen Ziziphi Spinosae, Fructus Lycii, the Fructus Jujubae of this product is the health food of the medicine-food two-purpose of Ministry of Public Health announcement; They not only have the effect of tranquillizing and allaying excitement, and at aspects such as human body immunity improving power, angiocardiopathy preventings good effect are arranged all.Fructus Schisandrae Chinensis has tangible tranquilizing effect, can also the strong liver of QI invigorating, promote efficient, supply more oxygen, the improving memory of cells exclude refuse; Effect characteristics and the Radix Ginseng of modern medicine research proof Radix Et Caulis Acanthopanacis Senticosi are basic identical, have the disorder of the body of adjusting, make it to be tending towards normal function, have good calm the nerves, antifatigue effect, and can significantly improve hypoxia-bearing capability; Radix Polygalae has effects such as calmness, blood pressure lowering, promotion muscle power and intelligence; Semen Ziziphi Spinosae has mind tranquilizing and the heart calming, blood pressure lowering, blood fat reducing, anti-hypoxia, raise immunity and to the protective effect of heart; Fructus Lycii also has the enhancing human body immunity function, suppresses tumor, blood sugar lowering, blood fat reducing, functions such as resisting fatigue; Fructus Jujubae can also improve body immunity, reduces serum cholesterol, improve serum albumin, the liver protecting except mind tranquilizing and the heart calming.
The present invention carries out scientific and reasonable compatibility with Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi, Radix Polygalae, Semen Ziziphi Spinosae, Fructus Lycii, Fructus Jujubae, makes it to act on target spots different in the body, forms many target spot mechanism, thereby produces the good sleeper effect that improves.Compare with other improvement sleep product, this product has the following advantages:
1) scientific formulation is reasonable.Product of the present invention is an index with effective ingredient such as flavone, Saponins, rationally prepares, and favorable effects is not only arranged, and has guaranteed its safety.
2) several kinds of materials in the compound improvement sleep electuary have synergism, and they act on the different target spots of body, obtain the good sleeper effect that improves.
3) the product scope of application is wide.The present invention with Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi, Radix Polygalae, Semen Ziziphi Spinosae, Fructus Lycii, Fructus Jujubae extract processed and improved sleeping capsule; Because these several kinds of materials all belong to the article of medicine-food two-purpose; The effect that human body is produced does not have physical difference, is fit to most crowds.
4) production technology of the present invention is simple, with low cost, economic benefit good, be easy to popularization.
5) the present invention is easy to carry about with one, instant.
The compound effect (table 1) of improving sleeping capsule: the compound sleeping capsule that improves is sooner or later respectively obeyed one every day, takes 14 days, and observation in the 15th ~ 21 day has tangible curative effect.Volunteer's sleep quality has clear improvement, and time for falling asleep shortens, and prolong the length of one's sleep, no obvious adverse reaction.The volunteer is the student in school and teacher, is the insomniac due to be a cup too low disease and the severe organic disease, does not take spirit type medicine taking this product the last fortnight, and does not have major disease.
Table 1
| Group | Total number of persons | Age | Take preceding symptom | Take the back symptom | The responder | Effective percentage |
| 1 | 45 | 19~40 | Sleep quality is bad, dreaminess | Sleep quality improves, few dream | 31 | 68.9% |
| 2 | 40 | 23~45 | Difficulty falling asleep | Time for falling asleep obviously shortens | 24 | 60% |
| 3 | 40 | 24~50 | The length of one's sleep is short | Prolong the length of one's sleep, and morning, wake-up time postponed | 25 | 62.5% |
Annotate: these article non-drug, generic health product.
The specific embodiment
The specific embodiment one: the compound sleeping capsule that improves is processed by 45 ~ 55% extract extractum and 45 ~ 55% pregelatinized Starch by mass percentage in this embodiment.Wherein extract extractum is processed by 30 ~ 35% Fructus Schisandrae Chinensis, 20 ~ 25% Radix Et Caulis Acanthopanacis Senticosis, 5 ~ 10% Radix Polygalaes, 10 ~ 15% Semen Ziziphi Spinosaes, 20 ~ 25% Fructus Lyciis and 5 ~ 10% Fructus Jujubae extracts by mass percentage.
Every 100g improves lignanoids 29 ~ 40mg, organic acid 313 ~ 325mg, polysaccharide 465 ~ 475mg, Saponin class 826 ~ 835mg, flavonoid 514 ~ 525mg, the flavonoid glycoside 61 ~ 70mg in the sleep electuary.
The specific embodiment two: the compound sleeping capsule that improves prepares according to the following steps in this embodiment:
1) prepares each main extract that divides: take by weighing Fructus Schisandrae Chinensis 30%, Radix Et Caulis Acanthopanacis Senticosi 24%, Radix Polygalae 8%, Semen Ziziphi Spinosae 10%, Fructus Lycii 20%, Fructus Jujubae 8% fine powder; Ratio with solid-liquid ratio 1g:3ml ~ 1g:5ml adds water; Boiled 1 hour with slow fire, filter then, repeat to boil 3 times; Merge extractive liquid, also is concentrated into paste, and it is subsequent use to get each main extract that divides.
2) by 45% extractum and 55% pregelatinized Starch mix homogeneously, and put into vacuum drying oven and dry, dried mixture is pulverized, sieve, incapsulate and promptly get the compound sleeping capsule that improves.
Wherein, compound lignanoids 29.4mg, organic acid 312.667mg, polysaccharide 465.02mg, Saponin class 826.42mg, flavonoid 513.6mg, the flavonoid glycoside 61.2mg in the sleeping capsule that improve that improves in the sleeping capsule of per 100 grams.
The specific embodiment three: what this embodiment and embodiment one, two were different is that the mass percent of each raw material is Fructus Schisandrae Chinensis 32%, Radix Et Caulis Acanthopanacis Senticosi 22%, Radix Polygalae 8%, Semen Ziziphi Spinosae 12%, Fructus Lycii 20%, Fructus Jujubae 6%.
The specific embodiment four: what this embodiment and embodiment one, two, three were different is that the mass percent of each raw material is Fructus Schisandrae Chinensis 34%, Radix Et Caulis Acanthopanacis Senticosi 20%, Radix Polygalae 6%, Semen Ziziphi Spinosae 11%, Fructus Lycii 22%, Fructus Jujubae 7%.
The specific embodiment five: what this embodiment and embodiment one, two, three, four were different is that the mass percent of each raw material is Fructus Schisandrae Chinensis 35%, Radix Et Caulis Acanthopanacis Senticosi 23%, Radix Polygalae 7%, Semen Ziziphi Spinosae 10%, Fructus Lycii 20%, Fructus Jujubae 5%.
Claims (6)
1. the compound sleeping capsule that improves; It is characterized in that said capsule processed by 45 ~ 55% extract extractum and 45 ~ 55% pregelatinized Starch by mass percentage, wherein extract extractum is processed by 30 ~ 35% Fructus Schisandrae Chinensis, 20 ~ 25% Radix Et Caulis Acanthopanacis Senticosis, 5 ~ 10% Radix Polygalaes, 10 ~ 15% Semen Ziziphi Spinosaes, 20 ~ 25% Fructus Lyciis and 5 ~ 10% Fructus Jujubae extracts by mass percentage.
2. the compound sleeping capsule that improves according to claim 1, the mass percent that it is characterized in that said extract extractum are Fructus Schisandrae Chinensis 30%, Radix Et Caulis Acanthopanacis Senticosi 24%, Radix Polygalae 8%, Semen Ziziphi Spinosae 10%, Fructus Lycii 20%, Fructus Jujubae 8%.
3. the compound sleeping capsule that improves according to claim 1, the mass percent that it is characterized in that said extract extractum are Fructus Schisandrae Chinensis 32%, Radix Et Caulis Acanthopanacis Senticosi 22%, Radix Polygalae 8%, Semen Ziziphi Spinosae 12%, Fructus Lycii 20%, Fructus Jujubae 6%.
4. the compound sleeping capsule that improves according to claim 1, the mass percent that it is characterized in that said extract extractum are Fructus Schisandrae Chinensis 34%, Radix Et Caulis Acanthopanacis Senticosi 20%, Radix Polygalae 6%, Semen Ziziphi Spinosae 11%, Fructus Lycii 22%, Fructus Jujubae 7%.
5. the compound sleeping capsule that improves according to claim 1, the mass percent that it is characterized in that said extract extractum are Fructus Schisandrae Chinensis 35%, Radix Et Caulis Acanthopanacis Senticosi 23%, Radix Polygalae 7%, Semen Ziziphi Spinosae 10%, Fructus Lycii 20%, Fructus Jujubae 5%.
6. said compound method for preparing of improving sleeping capsule of claim 1 is characterized in that said method is:
1) prepares each main extract that divides: take by weighing Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi, Radix Polygalae, Semen Ziziphi Spinosae, Fructus Lycii, Fructus Jujubae fine powder in claim 1 said ratio; Behind its uniform mixing, add water with the ratio of solid-liquid ratio 1g:3 ~ 5ml, boil with slow fire; Filter then; Repeat to boil 3 times, merge extractive liquid, also is concentrated into paste, and it is subsequent use to get each main mixed extract extractum that divides;
2) be that the mixed of 45 ~ 55% extract extractum and 45 ~ 55% pregelatinized Starch is even by mass percentage, and put into vacuum drying oven and dry, dried mixture is pulverized, sieve, incapsulate and promptly get the compound sleeping capsule that improves.
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| CN103202896A (en) * | 2013-02-04 | 2013-07-17 | 北华大学 | Tranquillizing, allaying and sleep-promoting oral liquid and preparation method thereof |
| CN107334142A (en) * | 2017-06-23 | 2017-11-10 | 天津金匮堂生物科技有限公司 | A kind of deficiency of heart-blood that improves causes health products of insomnia and preparation method thereof |
| CN108338297A (en) * | 2018-01-31 | 2018-07-31 | 佳木斯大学 | A kind of mind-tranquilizing brain-strengthening health beverages and preparation method thereof |
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| CN103202896A (en) * | 2013-02-04 | 2013-07-17 | 北华大学 | Tranquillizing, allaying and sleep-promoting oral liquid and preparation method thereof |
| CN107334142A (en) * | 2017-06-23 | 2017-11-10 | 天津金匮堂生物科技有限公司 | A kind of deficiency of heart-blood that improves causes health products of insomnia and preparation method thereof |
| CN108338297A (en) * | 2018-01-31 | 2018-07-31 | 佳木斯大学 | A kind of mind-tranquilizing brain-strengthening health beverages and preparation method thereof |
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| CN102614315B (en) | 2013-10-16 |
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