CN102600299A - Compound granules for improving sleeping and preparation method thereof - Google Patents

Compound granules for improving sleeping and preparation method thereof Download PDF

Info

Publication number
CN102600299A
CN102600299A CN2012101215389A CN201210121538A CN102600299A CN 102600299 A CN102600299 A CN 102600299A CN 2012101215389 A CN2012101215389 A CN 2012101215389A CN 201210121538 A CN201210121538 A CN 201210121538A CN 102600299 A CN102600299 A CN 102600299A
Authority
CN
China
Prior art keywords
fructus
radix
electuary
schisandrae chinensis
semen ziziphi
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2012101215389A
Other languages
Chinese (zh)
Inventor
王振宇
王蕾
张华�
伊娟娟
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Harbin Institute of Technology
Original Assignee
Harbin Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harbin Institute of Technology filed Critical Harbin Institute of Technology
Priority to CN2012101215389A priority Critical patent/CN102600299A/en
Publication of CN102600299A publication Critical patent/CN102600299A/en
Pending legal-status Critical Current

Links

Landscapes

  • Medicines Containing Plant Substances (AREA)

Abstract

The invention provides compound granules for improving sleeping and a preparation method thereof, relates to a product for improving sleeping and a preparation method thereof, and aims to solve the problem that most conventional products for improving sleeping have dependence and side effects. The compound granules comprise the following main raw materials in percentage by mass: 30 to 35 percent of Chinese magnoliavine fruit, 20 to 25 percent of acanthopanax root, 5 to 10 percent of polygala tenuifolia, 10 to 15 percent of spina date seed, 20 to 25 percent of medlar, and 5 to 10 percent of Chinese date. The preparation method comprises the following steps: crushing the raw materials; extracting by a decoction method; concentrating the extract into extract to prepare the granules. The product contains a plurality of extracts, has rich nutrients besides the function of improving sleeping, and has the advantages of simple preparation process, low cost, excellent economic benefit and easiness in popularization.

Description

Compound improvement sleep electuary and preparation method thereof
Technical field
The present invention relates to a kind of improvement sleep product and preparation method thereof.
Background technology
Along with the development of society, people's life stress increases day by day, because the influence of various factors, sleep disorder is also more and more general with the phenomenon of not having enough sleep.
The most frequently used method of treatment sleep disorder is with chemosynthesis class sedative hypnotic at present, though have certain effect, takes for a long time and can produce certain dependency and side effect.Active component in the natural plants more and more receives extensive concern because its side effect is little, safe, it is wide to adapt to.In recent years domestic research worker conducts a research to the sedative-hypnotic effect of Chinese herbal medicine, finds that wherein many active component have the effect of tranquillizing and allaying excitement.
Summary of the invention
The purpose of this invention is to provide a kind of compound improvement sleep electuary and preparation method thereof, solved most of existing improvement sleep products and had the problem of dependency and side effect.This product contains multiple extract, except the effect of improving sleep is arranged, also contains abundant nutrient.
Compound improvement sleep electuary of the present invention is that primary raw material processes with 30 ~ 35% Fructus Schisandrae Chinensis, 20 ~ 25% Radix Et Caulis Acanthopanacis Senticosis, 5 ~ 10% Radix Polygalaes, 10 ~ 15% Semen Ziziphi Spinosaes, 20 ~ 25% Fructus Lyciis and 5 ~ 10% Fructus Jujubaes by mass percentage.
The present invention prepares compound improvement sleep electuary according to following steps:
1) prepares each main extract that divides: take by weighing Fructus Schisandrae Chinensis (30 ~ 35 parts), Radix Et Caulis Acanthopanacis Senticosi (20 ~ 25 parts), Radix Polygalae (5 ~ 10), Semen Ziziphi Spinosae (10 ~ 15 parts), Fructus Lycii (20 ~ 25 parts), Fructus Jujubae (5 ~ 10 parts) fine powder by weight respectively; With these fine powder mix homogeneously, be that the ratio of 1g:3 ~ 5ml adds water with the solid-liquid ratio, boiled 1 hour with slow fire; Filter then; Repeat to boil 3 times, merge extractive liquid, also is concentrated into paste, and it is subsequent use to obtain each main mixed extract extractum that divides;
2) preparation of Icing Sugar:, break into fine powder with subsequent use with the white sugar oven dry;
3) be that 30 ~ 40% extract extractum and 60 ~ 70% Icing Sugar mix homogeneously carry out pelletize by mass percentage, and put into vacuum drying oven and dry that temperature is 45 ~ 55 ℃, sieves after the oven dry, promptly get compound improvement sleep electuary.
Containing lignanoids content in the compound improvement sleep of the every 100g electuary is that 15 ~ 25mg, organic acid content are that 185 ~ 195mg, polysaccharide content are that 280 ~ 290mg, Saponin class content are that 495 ~ 505mg, flavonoid content are 310 ~ 320mg.
Used raw material Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi, Radix Polygalae, Semen Ziziphi Spinosae, Fructus Lycii, the Fructus Jujubae of compound improvement sleep electuary of the present invention is the health food of the medicine-food two-purpose of Ministry of Public Health announcement; They not only have the effect of tranquillizing and allaying excitement, and at aspects such as human body immunity improving power, angiocardiopathy preventings good effect are arranged all.Fructus Schisandrae Chinensis has tangible tranquilizing effect, can also the strong liver of QI invigorating, promote efficient, supply more oxygen, the improving memory of cells exclude refuse; Effect characteristics and the Radix Ginseng of modern medicine research proof Radix Et Caulis Acanthopanacis Senticosi are basic identical, have the disorder of the body of adjusting, make it to be tending towards normal function, have good calm the nerves, antifatigue effect, and can significantly improve hypoxia-bearing capability; Radix Polygalae has effects such as calmness, blood pressure lowering, promotion muscle power and intelligence; Semen Ziziphi Spinosae has mind tranquilizing and the heart calming, blood pressure lowering, blood fat reducing, anti-hypoxia, raise immunity and to the protective effect of heart; Fructus Lycii also has the enhancing human body immunity function, suppresses tumor, blood sugar lowering, blood fat reducing, functions such as resisting fatigue; Fructus Jujubae can also improve body immunity, reduces serum cholesterol, improve serum albumin, the liver protecting except mind tranquilizing and the heart calming.
The present invention carries out scientific and reasonable compatibility with Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi, Radix Polygalae, Semen Ziziphi Spinosae, Fructus Lycii, Fructus Jujubae, makes it to act on target spots different in the body, forms many target spot mechanism, thereby produces the good sleeper effect that improves.Compare with other improvement sleep product, this product has the following advantages:
1) scientific formulation is reasonable.Product of the present invention is an index with effective ingredient such as flavone, Saponins, rationally prepares, and favorable effects is not only arranged, and has guaranteed its safety.
2) several kinds of materials in the compound improvement sleep electuary have synergism, and they act on the different target spots of body, obtain the good sleeper effect that improves.
3) the product scope of application is wide.The present invention with Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi, Radix Polygalae, Semen Ziziphi Spinosae, Fructus Lycii, Fructus Jujubae extract processed and improved the sleep electuary; Because these several kinds of materials all belong to the article of medicine-food two-purpose; The effect that human body is produced does not have physical difference, is fit to most crowds.
4) production technology of the present invention is simple, with low cost, economic benefit good, be easy to popularization.
5) the present invention is easy to carry about with one, instant.
The effect (table 1) of compound improvement sleep electuary: compound improvement sleep electuary is slept and used warm boiled water 10g in last hour every night, takes 14 days, and observing in the 15th ~ 21 day has tangible curative effect.Volunteer's sleep quality has clear improvement, and time for falling asleep shortens, and prolong the length of one's sleep, no obvious adverse reaction.The volunteer is the student in school and teacher, is the insomniac due to be a cup too low disease and the severe organic disease, takes this product the last fortnight and does not take spirit type medicine, and do not have the bigger disease of other influences.
Table 1
Group Total number of persons Age Take preceding symptom Take the back symptom The responder Effective percentage
1 30 19~40 Sleep quality is bad, dreaminess Sleep quality improves, few dream 22 73.3%
2 40 23~45 Difficulty falling asleep Time for falling asleep shortens 26 65%
3 40 24~50 The length of one's sleep is short Prolong the length of one's sleep, and morning, wake-up time postponed 29 67.5%
Annotate: these article non-drug, generic health product.
The specific embodiment
The specific embodiment one: the compound improvement sleep electuary of this embodiment is processed by 30 ~ 40% extract extractum and 60 ~ 70% Icing Sugar by mass percentage; Wherein extract extractum is that raw material is processed with 30 ~ 35% Fructus Schisandrae Chinensis, 20 ~ 25% Radix Et Caulis Acanthopanacis Senticosis, 5 ~ 10% Radix Polygalaes, 10 ~ 15% Semen Ziziphi Spinosaes, 20 ~ 25% Fructus Lyciis and 5 ~ 10% Fructus Jujubaes by mass percentage.
The lignanoids content that every 100g improves in the sleep electuary is that 15 ~ 25mg, organic acid content are that 185 ~ 195mg, polysaccharide content are that 280 ~ 290mg, Saponin class content are that 495 ~ 505mg, flavonoid content are 310 ~ 320mg.
The specific embodiment two: compound improvement sleep electuary prepares according to the following steps in this embodiment:
1) prepares each main extract that divides: take by weighing Fructus Schisandrae Chinensis 34%, Radix Et Caulis Acanthopanacis Senticosi 22%, Radix Polygalae 9%, Semen Ziziphi Spinosae 10%, Fructus Lycii 20%, Fructus Jujubae 5% fine powder respectively by mass fraction; With its mix homogeneously, add water with the ratio of solid-liquid ratio 1g:3 ~ 5ml, boiled 1 hour with slow fire; Filter then; Repeat to boil 3 times, merge extractive liquid, also is concentrated into paste, and it is subsequent use to get each main extractum of mixed extract that divides.
2) preparation of Icing Sugar:, break into fine powder with subsequent use with the white sugar oven dry.
3) be 40% extract extractum and 60% Icing Sugar mix homogeneously pelletize by mass percentage, and put into vacuum drying oven and dry, sieve, promptly get compound improvement sleep electuary.
Wherein, the lignanoids content in the improvement sleep electuary in the compound improvement sleep of the per 100 grams electuary is that 17.64mg, organic acid content are that 187.6mg, polysaccharide content are that 279mg, Saponin class content are that 496mg, flavonoid content are 310mg.
The specific embodiment three: what this embodiment and embodiment one, two were different is that each raw materials quality percentage ratio is Fructus Schisandrae Chinensis 30%, Radix Et Caulis Acanthopanacis Senticosi 23%, Radix Polygalae 10%, Semen Ziziphi Spinosae 12%, Fructus Lycii 20%, Fructus Jujubae 5%.
The specific embodiment four: what this embodiment and embodiment one, two, three were different is that each raw materials quality percentage ratio is Fructus Schisandrae Chinensis 32%, Radix Et Caulis Acanthopanacis Senticosi 24%, Radix Polygalae 8%, Semen Ziziphi Spinosae 8%, Fructus Lycii 22%, Fructus Jujubae 6%.
The specific embodiment five: what this embodiment and embodiment one, two, three, four were different is that the mass percent of each raw material is Fructus Schisandrae Chinensis 35%, Radix Et Caulis Acanthopanacis Senticosi 20%, Radix Polygalae 10%, Semen Ziziphi Spinosae 10%, Fructus Lycii 20%, Fructus Jujubae 5%.

Claims (6)

1. compound improvement sleep electuary is characterized in that said electuary by mass percentage, is that primary raw material processes with 30 ~ 35% Fructus Schisandrae Chinensis, 20 ~ 25% Radix Et Caulis Acanthopanacis Senticosis, 5 ~ 10% Radix Polygalaes, 10 ~ 15% Semen Ziziphi Spinosaes, 20 ~ 25% Fructus Lyciis and 5 ~ 10% Fructus Jujubaes.
2. compound improvement sleep electuary according to claim 1 is characterized in that said mass percent is Fructus Schisandrae Chinensis 34%, Radix Et Caulis Acanthopanacis Senticosi 22%, Radix Polygalae 9%, Semen Ziziphi Spinosae 10%, Fructus Lycii 20%, Fructus Jujubae 5%.
3. compound improvement sleep electuary according to claim 1 is characterized in that said mass percent is Fructus Schisandrae Chinensis 30%, Radix Et Caulis Acanthopanacis Senticosi 23%, Radix Polygalae 10%, Semen Ziziphi Spinosae 12%, Fructus Lycii 20%, Fructus Jujubae 5%.
4. compound improvement sleep electuary according to claim 1 is characterized in that said mass percent is Fructus Schisandrae Chinensis 32%, Radix Et Caulis Acanthopanacis Senticosi 24%, Radix Polygalae 8%, Semen Ziziphi Spinosae 8%, Fructus Lycii 22%, Fructus Jujubae 6%.
5. compound improvement sleep electuary according to claim 1 is characterized in that said mass percent is Fructus Schisandrae Chinensis 35%, Radix Et Caulis Acanthopanacis Senticosi 20%, Radix Polygalae 10%, Semen Ziziphi Spinosae 10%, Fructus Lycii 20%, Fructus Jujubae 5%.
6. the method for preparing of the said compound improvement sleep electuary of a claim 1 is characterized in that said method is:
1) prepares each main extract that divides: take by weighing Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi, Radix Polygalae, Semen Ziziphi Spinosae, Fructus Lycii, Fructus Jujubae respectively by claim 1 said proportioning; Mix homogeneously is that the ratio of 1g:3 ~ 5ml adds water with the solid-liquid ratio, boils with slow fire; Filter then; Repeat to boil 3 times, merge extractive liquid, also is concentrated into paste, and it is subsequent use to obtain each main mixed extract extractum that divides;
2) preparation of Icing Sugar:, break into fine powder with subsequent use with the white sugar oven dry;
3) be that 30 ~ 40% extract extractum and 60 ~ 70% Icing Sugar mix homogeneously carry out pelletize by mass percentage, and put into vacuum drying oven and dry that temperature is 45 ~ 55 ℃, sieves after the oven dry, promptly get compound improvement sleep electuary.
CN2012101215389A 2012-04-24 2012-04-24 Compound granules for improving sleeping and preparation method thereof Pending CN102600299A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2012101215389A CN102600299A (en) 2012-04-24 2012-04-24 Compound granules for improving sleeping and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2012101215389A CN102600299A (en) 2012-04-24 2012-04-24 Compound granules for improving sleeping and preparation method thereof

Publications (1)

Publication Number Publication Date
CN102600299A true CN102600299A (en) 2012-07-25

Family

ID=46518318

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2012101215389A Pending CN102600299A (en) 2012-04-24 2012-04-24 Compound granules for improving sleeping and preparation method thereof

Country Status (1)

Country Link
CN (1) CN102600299A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103989935A (en) * 2014-05-15 2014-08-20 安徽科技学院 Medicinal wine for tranquilizing mind by nourishing the heart and preparation method thereof
CN104544406A (en) * 2015-02-09 2015-04-29 哈尔滨工业大学 Chinese-date-flavor functional beverage capable of improving sleep quality of spacemen and preparation method of Chinese-date-flavor functional beverage
CN104547285A (en) * 2014-12-25 2015-04-29 电白县南药药业有限公司 Composition containing eaglewood leaves for soothing nerves and promoting sleep
CN106728840A (en) * 2017-01-16 2017-05-31 中悦民安(北京)科技发展有限公司 A kind of domestic animal is calmed the nerves and promotees strong Chinese medicine composition and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101450122A (en) * 2008-12-30 2009-06-10 南京中医药大学 Traditional Chinese medicine preparation for treating insomnia and preparation method and use thereof
CN101642176A (en) * 2009-06-11 2010-02-10 杭州六易科技有限公司 Method for preparing wild jujube honey tea for relieving neurasthenia
CN101703622A (en) * 2009-09-17 2010-05-12 杭州六易科技有限公司 Preparation method of buccal tablet for improving sleeping

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101450122A (en) * 2008-12-30 2009-06-10 南京中医药大学 Traditional Chinese medicine preparation for treating insomnia and preparation method and use thereof
CN101642176A (en) * 2009-06-11 2010-02-10 杭州六易科技有限公司 Method for preparing wild jujube honey tea for relieving neurasthenia
CN101703622A (en) * 2009-09-17 2010-05-12 杭州六易科技有限公司 Preparation method of buccal tablet for improving sleeping

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
戴飞: "失眠的中医保健疗法", 《农村百事通》 *
袁光辉等: "失眠症治疗药物的研究进展", 《临床肺科杂志》 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103989935A (en) * 2014-05-15 2014-08-20 安徽科技学院 Medicinal wine for tranquilizing mind by nourishing the heart and preparation method thereof
CN103989935B (en) * 2014-05-15 2017-01-04 安徽科技学院 A kind of tranquilizing by nourishing the heart medicated wine and preparation method thereof
CN104547285A (en) * 2014-12-25 2015-04-29 电白县南药药业有限公司 Composition containing eaglewood leaves for soothing nerves and promoting sleep
CN104547285B (en) * 2014-12-25 2018-11-27 电白县南药药业有限公司 A kind of composition that containing eaglewood leaf, soothing nerves and assisting sleep is slept
CN104544406A (en) * 2015-02-09 2015-04-29 哈尔滨工业大学 Chinese-date-flavor functional beverage capable of improving sleep quality of spacemen and preparation method of Chinese-date-flavor functional beverage
CN106728840A (en) * 2017-01-16 2017-05-31 中悦民安(北京)科技发展有限公司 A kind of domestic animal is calmed the nerves and promotees strong Chinese medicine composition and preparation method thereof

Similar Documents

Publication Publication Date Title
CN104388265B (en) A kind of kidney-nourishing health tonic wine and preparation method thereof
CN102697047B (en) Method for preparing oral liquid of Chinese wolfberry
CN102640829B (en) Tea paste with myocardial ischemia function improving function and preparation method of tea paste
CN101229213A (en) Rhodiola rosea compound healthy product
CN103355619B (en) Fructus phyllanthi and Radix Puerariae health food
CN105055648A (en) Anti-aging Chinese herbal medicinal health oral liquid containing shark cartilage powder and preparation method of oral liquid
CN101703622B (en) Preparation method of buccal tablet for improving sleeping
CN102579836B (en) Traditional Chinese medical dendrobium huoshanense composition and preparation method thereof
CN102600299A (en) Compound granules for improving sleeping and preparation method thereof
CN105167106A (en) Rose health beverage having efficacy for delaying senility
CN103520519A (en) Gastrodia elata submicron powder effervescent tablet and preparation method thereof
CN102614315B (en) Compound sleeping-improving capsule and preparation method thereof
CN101468103A (en) Liver-protecting product and method for preparing the same
CN103349121A (en) Hyperglycemia-hyperlipidemia-hypertension relieving health protection tea and preparation method thereof
CN103725555A (en) Wild banana and oxhorn banana health-care wine for assisting blood pressure reduction and preparation method thereof
CN102441069A (en) Prebiotic longevity tablet and its preparation method
CN103520302B (en) Sea-buckthorn leaf anti-fatigue capsule and preparation method thereof
CN102613648B (en) Preparation method of original ecological bamboo germanium nutrient solution
CN109674885A (en) A kind of maintenance prescription for mental worker or frequent alcohol user
CN102613628B (en) Original ecological coconut germanium juice and producing method thereof
CN102198178B (en) Traditional Chinese medicine capsule for treating insomnia, amnesia, insufficient blood supply, and the like
CN101912460B (en) Preparation method for improving ginsenoside-containing Chinese medicinal extract quality
CN102599312B (en) Oligosaccharide Panax notoginseng sweet tea and preparation method thereof
CN107412369A (en) A kind of sanchi flower sleeping Pharmaceutical composition
CN102805179A (en) Nanoscale tea powder containing acanthopanax and ginseng ingredients and preparation method thereof

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20120725