CN102579969B - Traditional Chinese medicinal preparation for treating anxiety disorder - Google Patents

Abstract

The invention relates to a traditional Chinese medicinal preparation with a favorable treatment effect and a small side effect for treating anxiety disorder. The aim of the invention is achieved in a way that the traditional Chinese medicinal preparation is prepared from the following raw materials in parts by weight: 35-70 parts of arisaema cum bile, 30-80 parts of pinellia tuber, 25-60 parts of fruit of immature citron, 30-80 parts of aiomatic turmeric root-tuber, 70-110 parts of unibract fritillary bulb, 15-50 parts of calculus bovis artifactus, 10-50 parts of bamboo shavings, 20-60 parts of tukahoe, 30-75 parts of milkwort, 2-70 parts of cortex albiziae, 20-75 parts of common selfheal fruit-spike, 20-75 parts of coptis root, 5-35 parts of cordyceps sinensis and 30-85 parts of licorice root by mixing, extracting and purifying to form powder. The traditional Chinese medicinal preparation is a clinical experience formula in plastic surgery hospital and is deeply favored by patients due to the remarkable curative effect.

Description

The Chinese medicine preparation for the treatment of anxiety neurosis

(1), technical field

What the present invention relates to is a kind of medical configuration product, a kind of Chinese medicine preparation that is used for the treatment of anxiety neurosis specifically.

(2), background technology

Anxiety neurosis is a kind of disease with persistency anxiety, fear, intense strain and vegetative nerve moving obstacle, often and body sense of discomfort uneasy with the mobility.Regular incidence is between twenty and fifty phase, men and women's both sexes sickness rate no significant difference.Anxiety neurosis prevalence in the crowd is high, and main manifestations is sleep disorder, anxiety and autonomic nervous system dysfunction symptom.Epidemiological study shows that in urban population, nearly 4.1-6.6% can obtain anxiety neurosis.The premorbid personality of anxiety neurosis is mostly timid, feels oneself inferior suspicious, does things and ponders on the past and future, irresolute, can not adapt to very soon new things and new environment.Pathogenic factor is Nervous and Mental Factors, as is in nervous environment and can not adapts to, and meets with an misfortune or is difficult to bear more complicated and the work of difficulty etc.The normal person is facing the difficulty or adventurous task, when disadvantageous situation or dangerous the generation will occur in premonition, can produce anxiety (a kind of do not have clear and definite reason, tense situation beastly), this anxiety does not form disease usually, is a kind of normal mental status.Anxiety is not bad thing, and anxiety often can impel you to heave strength, go to deal with imminent crisis (in other words anxiety be a kind of actively stress instinct).Only have when the degree of anxiety and persistent period surpass certain scope and just form anxiety symptom, the crisis that this can play, and opposite effect-obstructions people deals with, treated side is front, even hinder orthobiosis.May be most of the time, do not have what clear and definite reason to experience anxiety; In fact do not do anying.Anxiety symptom also sees affective psychosis, schizophrenia, obsessive compulsive neurosis, hysteria, organic confusional state, hyperthyroidism etc.So " anxiety neurosis " of broad sense is the general name of a very large class obstacle, also comprise obstacle etc. after obsession, phobia, paranoid fears, wound.Here said anxiety neurosis is narrow sense, is called general anxiety disease in formal diagnosis.Think at present to only have the agnogenio aobvious of anxiety or degree is unbecoming, anxiety symptom is very outstanding and other symptoms are also not obvious, and than long time, just is diagnosed as anxiety neurosis between time delay.

Anxiety has subjective experience and objective performance two aspects:

(1) anxiety: anxiety can be considered the terror that there is no clear and definite object and particular content.As if patient is greatly alarmed all day, on tenterhooks, always feels that disaster will befall or be dangerous extremely urgent, but patient also knows and in fact do not have what danger or threat, why does not so uneasyly but know.

(2) objective performance: have two kinds, first mobility's uneasiness: patient's flat both arms of stretching of closing one's eyes are forward pointed as seen symmetry and are slightly trembled; Muscular tone makes patient feel a tight feeling of fullness in the head, pain even that rear cervical region sends out discomfort stiff, and extremity and back ache are also common; Severe patient is on tenterhooks, and frequently does a little little tricks, if scratched one's head, rubs hands etc., even walks up and down, and can not sit quietly a moment.Another kind of objective performance is the plant function disorder, especially sympathetic various symptoms hyperactivity, as: xerostomia, a burst of rubescent turning white of face, perspire, cardiopalmus, breathing is urged, sensation of asphyxia, chest is stuffy, inappetence, constipation or diarrhea, abdominal distention, the urgent micturition frequent micturition, easily faint etc.

Usually to there is the symptom of above two aspects just can be defined as anxiety neurosis.Only have anxiety and be likely without any nbjective symptom personality trait or ordinary person occur under certain situation reaction (situation or the property expected anxiety).

In, Western medicine the treatment on difference

Western medicine is with direct nerve block method, benumbs and blocks conducting nerve, makes the patient reach within a certain period of time the state of an illness external effect stably.Advantage is instant effect; Shortcoming is that side effect is large, takes medicine all the life.The most frequently used medicine for the treatment of anxiety neurosis is Benzodiazepines, wherein commonly used to stabilize.Stable have rapid-action, but just like tired, drowsiness, tremble, the side effect such as irritability of blurred vision and abnormality, and not remarkable to improving the vegetative nerve function effect.Also have oryzanol and vitamin B1 all to belong to Neurotrophic drugs.

The pathogenesis of anxiety neurosis is mainly mental disorder pent-up, and many because pondering over too, long-pending melancholy is strongly fragrant for a long time, stagnation of QI Tianjin is poly-, and knot forms expectorant, mental disorder superinverse, upper dry emptying, abnormal mind, even can not be autonomous, usually appearance is not close with situation, there is no the worry of clear and definite object and particular content with frightened, or scream, call for help, with cardiopalmus, uncomfortable in chest, chest pain, dyspnea etc.Control the method for suitable promoting the circulation of QI and reducing phlegm.

Based on current market situation, anxiety neurosis is clinical comparatively common, patient is painful large, and its sickness rate is in cumulative year after year, to the also corresponding increase of demand of medicine, however defectiveness on doctor trained in Western medicine, western medicine, but the treatment characteristic of Chinese medicine has but made up the deficiency of western modern medicine, therefore, the effective compound Chinese medicinal preparation of exploitation has become modern Chinese medicine people's the task of top priority.According to epidemiological study, show that in urban population, nearly 4.1-6.6% can obtain anxiety neurosis.In China, the patient of anxiety neurosis surpasses 400-600 ten thousand, annual being in hospital and approximately 30,000,000,000 yuan of the costs of outpatient service.The prolonged application chemotherapy can cause various untoward reaction, and patient's misery is larger.Therapeutic dose and toxic dose are very approaching, and individual variation is also larger, if take improperly, toxic reaction occur very easily.

This product is pure compound Chinese medicinal preparation, and long-term use and have small side effects, and drug effect is rapid, dosage is accurate, reliable effect, and this product is capsule formulation, leaches in vivo, absorption, produce effects be all better.And production equipment is simple, can produce in a large number.The medicine that is better than other dosage forms.Can predict, the batch production of this product has good market potential, the market demand.And this product is evident in efficacy in my institute's clinical practice for many years, deeply is subjected to patient's welcome.Through the relevant further investigation of the systems such as clinical pharmacology, after condition maturity, will declare new Chinese medicine, for this sick new force that increases is treated by China.

(3) summary of the invention

The object of the invention is to provide a kind of therapeutic effect good, the Chinese medicine preparation of the treatment anxiety neurosis that side effect is little.

The object of the present invention is achieved like this: it by weight portion is: Arisaema Cum Bile 35-70 part, Rhizoma Pinelliae 30-80 part, Fructus Aurantii Immaturus 25-60 part, Radix Curcumae 30-80 part, Bulbus Fritillariae Cirrhosae 70-110 part artificial Calculus Bovis 15-50 part, Caulis Bambusae In Taenia 10-50 part, Poria 20-60 part, Radix Polygalae 30-75 part, Cortex Albiziae 2-70 part, Spica Prunellae 20-75 part, Rhizoma Coptidis 20-75 part, Cordyceps 5-35 part, Radix Glycyrrhizae 30-85 part are made.

The present invention is my institute clinical experience prescription for many years, again through the clinical practice of 30 years, arranges and improves, due to the welcome that deeply is subjected to the patient evident in efficacy on the basis of traditional handicraft.

In side, Arisaema Cum Bile, the Rhizoma Pinelliae are monarch drug, the Arisaema Cum Bile removing heat-phlegm, and the power that Rhizoma Pinelliae drying dampness to eliminate phlegm, Papillary eliminate the phlegm is excellent.Minister is with Fructus Aurantii Immaturus, Radix Curcumae, the Fructus Aurantii Immaturus relieving stagnant and resolving masses, and the Radix Curcumae promoting QI circulation for relieving depression, Papillary, regulating the flow of vital energy is stagnant, and gas is disappeared along disease.Assistant is with the Bulbus Fritillariae Cirrhosae moistening the lung and resolving phlegm, artificial Calculus Bovis's removing heat-phlegm, and the Caulis Bambusae In Taenia stomach function regulating reduces phlegm, and the Poria dampness removing reduces phlegm, the power of principal drug assistance, and the merit of Poria tool spleen invigorating altogether, but the source of Du Sheng disease; Radix Polygalae, Cortex Albiziae are calmed the nerves Ning Zhi with except fidgety; The Spica Prunellae clearing away liver-fire, the Rhizoma Coptidis eliminating heart-fire, not only pathogenic fire reducing is conducive to the disease that disappears, outstanding damp proof that heat refining gathers for disease.Help less Cordyceps and both can reduce phlegm, help again to adjust after being ill benefit.Make with the Radix Glycyrrhizae mediation property of medicine.All medicine compatibilities, play activating QI to eliminate phlegm altogether, the effect of dissipating depression of QI mind calming.

Adopt the present invention to carry out the clinical observation test in the neural section hospital of Heilungkiang Kang Yuan, result of the test is listed following table in:

The routine clinical effectiveness for the treatment of anxiety neurosis 400

(3), the specific embodiment

Below for a more detailed description to the present invention for example: according to weight portion, be: the ratio of Arisaema Cum Bile 40-70 part, Rhizoma Pinelliae 40-80 part, Fructus Aurantii Immaturus 30-60 part, Radix Curcumae 40-80 part, Bulbus Fritillariae Cirrhosae 80-110 part artificial Calculus Bovis 20-50 part, Caulis Bambusae In Taenia 20-40 part, Poria 30-60 part, Radix Polygalae 30-65 part, Cortex Albiziae 25-65 part, Spica Prunellae 30-65 part, Rhizoma Coptidis 30-65 part, Cordyceps 5-25 part, Radix Glycyrrhizae 30-65 part is mixed, is extracted, is purified to powder by each raw material and makes.

Claims (1)

1. Chinese medicine preparation for the treatment of anxiety neurosis, it is characterized in that: according to weight portion be: powder constituent is mixed, extracted, is purified to the ratio of Arisaema Cum Bile 35-70 part, Rhizoma Pinelliae 30-80 part, Fructus Aurantii Immaturus 25-60 part, Radix Curcumae 30-80 part, Bulbus Fritillariae Cirrhosae 70-110 part artificial Calculus Bovis 15-50 part, Caulis Bambusae In Taenia 10-50 part, Poria 20-60 part, Radix Polygalae 30-75 part, Cortex Albiziae 2-70 part, Spica Prunellae 20-75 part, Rhizoma Coptidis 20-75 part, Cordyceps 5-35 part, Radix Glycyrrhizae 30-85 part by each raw material.