CN102579967A

CN102579967A - Traditional Chinese medicinal composition for treating lung cancer

Info

Publication number: CN102579967A
Application number: CN2011100076632A
Authority: CN
Inventors: 娄怡; 丁园园
Original assignee: Tianjin Zhongbao Pharmaceutical Co Ltd
Current assignee: Tianjin Zhongbao Pharmaceutical Co Ltd
Priority date: 2011-01-14
Filing date: 2011-01-14
Publication date: 2012-07-18

Abstract

The invention belongs to the field of traditional Chinese medicines and discloses a traditional Chinese medicinal composition for treating lung cancer. The traditional Chinese medicinal composition mainly comprises the following traditional Chinese medicinal components in parts by weight: 20-30g of snake gourd fruit, 15-30g of sophora flavescens, 15-30g of milkvetch root, 10-15g of white mulberry root-bark, 10-15g of ginseng, 10-15g of dwarf lilyturf root, 10-15g of almond, 10-15g of clematis root, 10-15g of polygonatum, 10-15g of ligusticum wallichii, 10-15g of oldenlandia diffusa, 6-15g of aiomatic turmeric root-tuber, 6-15g of turmeric, 6-15g of root-bark of tree peony and 6-15g of ginkgo. The traditional Chinese medicinal composition has the efficacies of clearing lung and eliminating phlegm and activating qi to resolve stagnation and as well as definite curative effect for patients suffering from lung cancer. The traditional Chinese medicinal composition is wide in application range and can be applied to lung cancer patients of various types and various stages; and meanwhile, the health of the patients can be maintained, the constitution can be enhanced and the states of the patients can be remarkably improved.

Description

A kind of Chinese medicine composition of treating pulmonary carcinoma

Technical field

The invention belongs to the field of Chinese medicines.

Background technology

Pulmonary carcinoma is modal lung primary malignant tumor, and most pulmonary carcinoma originate from the bronchial mucosa epithelium, so also claim lung bronchogenic carcinoma.20 beginning of the century pulmonary carcinoma all are rare tumor in the whole world, because smoking, over nearly more than 50 years; Countries in the world are industrially developed country particularly; The sickness rate of pulmonary carcinoma and case fatality rate all rise rapidly, and primary disease is many in morbidity more than 40 years old, and the age of onset peak is between 60～79 years old.Men and women's prevalence is 2.3: 1.Race, family members' history and smoking are all influential to the morbidity of pulmonary carcinoma.The andropathy philtrum pulmonary carcinoma of dying from carninomatosis ranks first.In women's common cancer, account for second or the 3rd.Be the No.1 killer of serious threat people ' s health and life.

Pulmonary carcinoma originates from the bronchial mucosa epithelium, is confined to that the person is called the cancer in situ cancerous protuberance in the basement membrane, can be in bronchial lumen or to the lung tissue growth that closes on, and can be through lymph blood capable or shift diffusion through bronchus.The carcinoma speed of growth and the situation that shifts diffusion have certain relation with biological characteristicses such as the histological type of carcinoma, differentiation degrees.The distribution situation right lung of pulmonary carcinoma is more than left lung, and last leaf all cancerous protuberance can take place more than inferior lobe from the main bronchus to the bronchioles.The pulmonary carcinoma that originates from main bronchus, lobar bronchi, the position is called central type carcinoma of lung near the hilus pulumonis person; Originate from the pulmonary carcinoma below the segmental bronchi, the position is called peripheral type carcinoma of lung peripheral part person of lung.Doctor trained in Western medicine thinks, pulmonary carcinoma to betide following risk factor relevant: radioactive substance such as long-term smoking, atmospheric pollution, occupational factor such as long-term contact uranium radium and chemical carcinogen, pulmonary's chronic disease such as pulmonary tuberculosis, pneumosilicosis, pneumoconiosis etc., human body intrinsic factor such as Inheritance and immune function reduce metabolic activity endocrine function imbalance etc.

Chinese medicine goes out to send understanding to the pathogenesis of pulmonary carcinoma from organic conception, and Chinese medicine thinks that the etiology and pathogenesis of lung cancer morbidity is that healthy energy interior-deficiency, expectorant coagulate poison and gathers and the internal organs imbalance of YIN and YANG.Pulmonary carcinoma is a systemic disease, and lung tumors is a topical manifestations in the systemic disease.Normally whole body belongs to empty, local true.The treatment primary disease should be under the theoretical concrete guide of Chinese medical discrimination; Just distinguish the deficiency and excess heresy, on the whole and local theoretical point view that combines, anticancer therapy and strengthening the body resistance treatment combine; Coryza Treated by Syndrome Differentiation combines with treatment according to differentiation of diseases; Can improve patient's clinical symptoms effectively, improve patient's quality of life, prolong patient's life-span.

Whether pulmonary carcinoma is treated according to different types at present and is shifted and take corresponding methods of treatment, mainly contains chemotherapy (small cell carcinoma), radiotherapy (small cell carcinoma is best, squamous cell carcinoma), operative treatment (non-small cell carcinoma) etc.Though in the effect that to a certain degree can play control pulmonary carcinoma progress, the toxicity that put, chemotherapy is brought is also very obvious, patient is usually agonizing.Chinese medicine pulmonary carcinoma not only can disease controlling develop, and can improve recent symptom, simultaneously chemicotherapy is played the effect of attenuation synergistic, alleviates less patient suffering.Strengthening the body resistance, eliminating evil, transfer body resistance against diseases, alleviate and effect of crucial importance and unique advantage are arranged aspect the side effect of other treatment.

Summary of the invention

The present invention aims to provide a kind of Chinese medicine composition of treating pulmonary carcinoma, so that provide more medications to select for clinical.

A kind of Chinese medicine composition of treating pulmonary carcinoma; Mainly comprise following traditional Chinese medicine components by weight ratio: Fructus Trichosanthis 20～30g; Radix Sophorae Flavescentis, each 15～30g of the Radix Astragali; Cortex Mori, Radix Ginseng, Radix Ophiopogonis, Semen Armeniacae Amarum, Radix Clematidis, Rhizoma Polygonati Odorati, Rhizoma Chuanxiong, each 10～15g of Herba Hedyotidis Diffusae, Radix Curcumae, Rhizoma Curcumae Longae, Cortex Moutan, each 6～15g of Semen Ginkgo.

Fructus Trichosanthis in the side, Herba Hedyotidis Diffusae, Radix Ophiopogonis, Rhizoma Polygonati Odorati, be monarch drug altogether, with the removing blood stasis that reduces phlegm, lung heat clearing is promoted the production of body fluid, and minister is with Semen Armeniacae Amarum, Radix Sophorae Flavescentis, Rhizoma Chuanxiong, play the merit of dispersing obstructed lung-QI, regulating qi to disperse stagnation, expectorant cough suppressant and anti-asthmatic altogether; Assistant is with anti-excessive consumption impairing the lung gas, the double usefulness of relievining asthma of dispersing of Semen Ginkgo; Radix Astragali tonifying QI to produce body fluid is harmonizing the spleen and stomach simultaneously, and the QI invigorating poison holding not only can the enhancing human body immunity function, and can anticancerly press down cancer; The Radix Clematidis liver and kidney tonifying, clearind deficient heat, removing obstruction for relieving pain.Its property of Radix Curcumae lightly floats, the stasis of loosing, along contrary gas, on reach high mountain peak, the benefaction part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, cardiopulmonary liver gastric qi blood fire-phlegm is strongly fragrant holds back not that passerby tests most, the hot few hardship of Rhizoma Curcumae Longae is many, property gas is Radix Curcumae too, removing blood stasis is upright logical, therapeutic method to keep the adverse QI flowing downwards steepest, all stagnation of QI pneumatosis, lump in the abdomen blood stasis; Blood closes carbuncle, and all effective.With the Radix Curcumae Rhizoma Curcumae Longae is to medicine, the removing blood stasis circulation of qi promoting, and QI and blood is held concurrently and is managed, and heightens the effect of a treatment.Can kill or suppress tumor cell effectively, and control the transfer and the diffusion of tumor, further improve the coefficient of stabilization of tumor, reach the effect that prolongs patient's life-span and remedy operative treatment, radiotherapy, chemotherapeutical deficiency.Operation no doubt can be excised cancerous protuberance, but also has in residual cancer or regional lymph node metastasis or the blood vessel cancer embolus existence etc., and the long-term treatment of utilization Chinese medicine postoperative can prevent recurrence and shifts.

The present invention has removing heat from the lung and dissipating phlegm, and the merit of regulating qi to disperse stagnation has definite curative effect to patients with lung cancer.And applied widely, can be applicable to all kinds patients with lung cancer in each period, the patient's healthy energy of can cultivating and looking after simultaneously, health invigorating also improves patient's oneself state significantly, and patient self antineoplastic ability is improved.

The specific embodiment

Example 1

Fructus Trichosanthis 20～30g, Radix Sophorae Flavescentis, each 15～30g of the Radix Astragali, Cortex Mori, Radix Ginseng, Radix Ophiopogonis, Semen Armeniacae Amarum, Radix Clematidis, Rhizoma Polygonati Odorati, Rhizoma Chuanxiong, each 10～15g of Herba Hedyotidis Diffusae, Radix Curcumae, Rhizoma Curcumae Longae, Cortex Moutan, each 6～15g of Semen Ginkgo.Cough with copious phlegm, indigestion and loss of appetite, spiritlessness and weakness uncomfortable in chest, the thin person in big loose stool add the Rhizoma Atractylodis Macrocephalae, Poria, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, each 10～15g of Semen Coicis.Two doses of every days, decocting extracting juice clothes are used to treat pulmonary carcinoma, 15 days courses of treatment.

Example 2

Fructus Trichosanthis 20～30g, Radix Sophorae Flavescentis, each 15～30g of the Radix Astragali, Cortex Mori, Radix Ginseng, Radix Ophiopogonis, Semen Armeniacae Amarum, Radix Clematidis, Rhizoma Polygonati Odorati, Rhizoma Chuanxiong, each 10～15g of Herba Hedyotidis Diffusae, Radix Curcumae, Rhizoma Curcumae Longae, Cortex Moutan, each 6～15g of Semen Ginkgo.Cough, no expectorant or few expectorant, chest pain are breathed hard, vexed insomnia, dry mouth and constipation person add respectively 10～15g of the Radix Rehmanniae, Radix Adenophorae (Radix Glehniae), Spica Prunellae 20～30g.Two doses of every days, decocting extracting juice clothes are used to treat pulmonary carcinoma, 15 days courses of treatment.

Example 3

Fructus Trichosanthis 20～30g, Radix Sophorae Flavescentis, each 15～30g of the Radix Astragali, Cortex Mori, Radix Ginseng, Radix Ophiopogonis, Semen Armeniacae Amarum, Radix Clematidis, Rhizoma Polygonati Odorati, Rhizoma Chuanxiong, each 10～15g of Herba Hedyotidis Diffusae, Radix Curcumae, Rhizoma Curcumae Longae, Cortex Moutan, each 6～15g of Semen Ginkgo.Fullness and distention in the chest and hypochondrium or twinge, constipation with dry stool, person add Radix Angelicae Sinensis, the Radix Rehmanniae, Semen Persicae, each 10g～15g of Fructus Toosendan.Two doses of every days, decocting extracting juice clothes are used to treat pulmonary carcinoma, 15 days courses of treatment.

Example 4

Fructus Trichosanthis 20～30g, Radix Sophorae Flavescentis, each 15～30g of the Radix Astragali, Cortex Mori, Radix Ginseng, Radix Ophiopogonis, Semen Armeniacae Amarum, Radix Clematidis, Rhizoma Polygonati Odorati, Rhizoma Chuanxiong, each 10～15g of Herba Hedyotidis Diffusae, Radix Curcumae, Rhizoma Curcumae Longae, Cortex Moutan, each 6～15g of Semen Ginkgo.Dizzy limb is tired, spiritlessness and sparing of words, moving then spontaneous perspiration, inappetence add Radix Angelicae Sinensis, Colla Corii Asini (melt is dashed), each 10～15g of Fructus Psoraleae, Rhizoma Atractylodis Macrocephalae (parched), Cornu Cervi tablet, Radix Rehmanniae Preparata, each 15～30g of Caulis Spatholobi.Two doses of every days, decocting extracting juice clothes are used to treat pulmonary carcinoma, 15 days courses of treatment.

Treat pulmonary carcinoma sufferer 34 examples with the present invention.Maximum 70 years old minimum 45 years old average 60.5 years old; With 15 days be a course of treatment, after three courses of treatment, therapeutic outcome: (patient is conscious energetic to cure 7 examples; Activity can necessarily expend bodily strength); Effective 22 examples (the conscious spirit of patient still can weak sx, can carry out general activity), total effective rate 85.3%.Invalid 2 examples.Do not see that toxic and side effects takes place.

Claims

1. Chinese medicine composition of treating pulmonary carcinoma; It is characterized in that; Mainly comprise following traditional Chinese medicine components by weight ratio: Fructus Trichosanthis 20～30g; Radix Sophorae Flavescentis, each 15～30g of the Radix Astragali, Cortex Mori, Radix Ginseng, Radix Ophiopogonis, Semen Armeniacae Amarum, Radix Clematidis, Rhizoma Polygonati Odorati, Rhizoma Chuanxiong, each 10～15g of Herba Hedyotidis Diffusae, Radix Curcumae, Rhizoma Curcumae Longae, Cortex Moutan, each 6～15g of Semen Ginkgo.

2. the Chinese medicine composition of treatment pulmonary carcinoma according to claim 1 is characterized in that, also comprises following traditional Chinese medicine components by weight ratio: the Rhizoma Atractylodis Macrocephalae, Poria, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Semen Coicis 10～15g.

3. the Chinese medicine composition of treatment pulmonary carcinoma according to claim 1 is characterized in that, also comprises following traditional Chinese medicine components by weight ratio: the Radix Rehmanniae, Radix Adenophorae (Radix Glehniae) 10～15g, Spica Prunellae 20～30g.

4. the Chinese medicine composition of treatment pulmonary carcinoma according to claim 1 is characterized in that, also comprises following traditional Chinese medicine components by weight ratio: Radix Angelicae Sinensis, Colla Corii Asini (melt is dashed), Fructus Psoraleae 10～15g, Rhizoma Atractylodis Macrocephalae (parched), Cornu Cervi tablet, Radix Rehmanniae Preparata, Caulis Spatholobi 15～30g.