CN106620518A - Traditional Chinese medicine composition as well as preparation method and application in treating lung cancer thereof - Google Patents
Traditional Chinese medicine composition as well as preparation method and application in treating lung cancer thereof Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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Abstract
The invention belongs to the technical field of medicines, and particularly discloses a traditional Chinese medicine composition as well as a preparation method and application in treating lung cancer thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10 to 36 parts of bark of taxus chinensis, 8 to 28 parts of red ginseng, 10 to 36 parts of liquorice root, 8 to 28 parts of semen strychni, 10 to 36 parts of pinellia tuber, 10 to 40 parts of radix astragali seu hedysari, 10 to 40 parts of venenum bufonis, 30 to 60 parts of radix curcumae, 10 to 40 parts of Chinese angelica, 5 to 25 parts of fructus psoraleae, 10 to 30 parts of herba agrimoniae, 8 to 28 parts of cordyceps, 5 to 20 parts of lucid ganoderma, 10 to 35 parts of radix notoginseng, 10 to 40 parts of ginkgo seed, and 5 to 25 parts of herba picriae. The traditional Chinese medicine composition has the advantages that the raw materials are mutually synergistic and are mutually compounded, so that the effects of invigorating Qi and strengthening body resistance, and detoxifying and resisting cancers are realized; after the components are subjected to solid state fermentation, macromolecules are changed into micromolecules, so that the components are absorbed by a human body in a 100% way, and the clinical therapy effect is obviously improved.
Description
Technical field
The invention belongs to pharmaceutical technology field, and in particular to a kind of Chinese medicine composition and preparation method thereof and treatment lung cancer
Using.
Background technology
It is most fast that lung cancer is that a kind of M ＆ M increases, the malignant tumour maximum to population health and life threat it
One.Immediate and mid-term, it was reported that trend is substantially increased in the M ＆ M presentation for claiming lung cancer.Now patients with lung cancer is typically adopted
Surgery excision, chemotherapy, the means of radiotherapy are treated, although operation can remove primary lesion, when malignant cell to
When other positions are shifted beyond original site, single surgery excision has not reached therapeutic purposes, and chemotherapy is used as a kind of unique
Whole body therapeutic means, more than 90% patients with lung cancer needs to receive chemotherapeutic treatment.Although chemotherapy has preferable to lung carcinoma cell
Curative effect, but the side effect that chemotherapy causes is also what is can not be ignored, and the medicine that chemotherapy is adopted belongs to cytotoxic drug, is killing cancer
While cell, larger harm is also generated to human normal cell.With the carrying out of chemotherapy, cause leucocyte and blood platelet
Decline；The digestive systems such as nausea,vomiting,diarrhea react；Cause alopecia；Hepatic and renal function suffers damage.
In recent years, traditional Chinese medicine is played because it has the advantages such as anticancer suppression is swollen, toxic and side effect is little in antitumor
Important function, but traditional Chinese medicine is typically using the active ingredient extracted in the method that family boils in medicinal material, but during family boils
The time of medicine, temperature, pressure are difficult to unify, therefore, it is difficult to determining the active constituent content extracted in medicinal material；What patient took
Decoction or Chinese patent drug, need to be digested again and decomposed by the probio of human body gastrointestinal system, can just be converted into and finally act as
Active ingredient and enter blood, if the flora of probio is unbalance in patient's gastrointestinal system, drug ingedient can not be effective
Decompose and then be absorbed by the body, then medicine cannot reach its due curative effect.
The content of the invention
For the above-mentioned problem of traditional Chinese medicine, the present invention provides a kind of Chinese medicine composition and preparation method thereof.
A kind of Chinese medicine composition that the present invention is provided, including the raw material of following weight portion：Bark of Ramulus et folium taxi cuspidatae 10～36, red ginseng 8
～28, Radix Glycyrrhizae 10～36, vomiting nut 8～28, the tuber of pinellia 10～36, the Radix Astragali 10～40, the dried venom of toads 10～40, root tuber of aromatic turmeric 30～60, Radix Angelicae Sinensis
10～40, Psoralea corylifolia 5～25, hairyvein agrimony 10～30, Cordyceps sinensis 8～28, glossy ganoderma 5～20, pseudo-ginseng 10～35, gingko 10～
40, picria fel tarrae 5～25.
Preferably, Chinese medicine composition of the present invention, including the raw material of following weight portion：It is 22～28 parts of bark of Ramulus et folium taxi cuspidatae, red
16～20 parts of ginseng, 22～25 parts of Radix Glycyrrhizae, 16～20 parts of vomiting nut, 22～28 parts of the tuber of pinellia, 22～27 parts of the Radix Astragali, the dried venom of toads 22～27
Part, 40～50 parts of root tuber of aromatic turmeric, 22～27 parts of Radix Angelicae Sinensis, 12～18 parts of Psoralea corylifolia, 18～22 parts of hairyvein agrimony, 15～20 parts of Cordyceps sinensis,
10～15 parts of glossy ganoderma, 20～25 parts of pseudo-ginseng, 22～27 parts of gingko, 10～14 parts of picria fel tarrae.
Preferably, Chinese medicine composition of the present invention, including the raw material of following weight portion：23 parts of bark of Ramulus et folium taxi cuspidatae, red ginseng 20
Part, 22 parts of Radix Glycyrrhizae, 18 parts of vomiting nut, 24 parts of the tuber of pinellia, 25 parts of the Radix Astragali, 26 parts of the dried venom of toads, 46 parts of root tuber of aromatic turmeric, 28 parts of Radix Angelicae Sinensis, Psoralea corylifolia 13
Part, 24 parts of hairyvein agrimony, 19 parts of Cordyceps sinensis, 13 parts of glossy ganoderma, 22 parts of pseudo-ginseng, 24 parts of gingko, 13 parts of picria fel tarrae.
Optimal, Chinese medicine composition of the present invention, including the raw material of following weight portion：23 parts of bark of Ramulus et folium taxi cuspidatae, red ginseng 18
Part, 23 parts of Radix Glycyrrhizae, 18 parts of vomiting nut, 23 parts of the tuber of pinellia, 25 parts of the Radix Astragali, 25 parts of the dried venom of toads, 45 parts of root tuber of aromatic turmeric, 25 parts of Radix Angelicae Sinensis, Psoralea corylifolia 15
Part, 20 parts of hairyvein agrimony, 18 parts of Cordyceps sinensis, 12 parts of glossy ganoderma, 22 parts of pseudo-ginseng, 25 parts of gingko, 12 parts of picria fel tarrae.
The Chinese medicine composition makes pharmaceutically acceptable preparation.
The preparation is any one in tablet, capsule, granule, powder or pill.
The invention further relates to the preparation method of the Chinese medicine composition, comprises the steps：The first step, weighs Chinese yew
Skin, red ginseng, Radix Glycyrrhizae, vomiting nut, the tuber of pinellia, the Radix Astragali, the dried venom of toads, root tuber of aromatic turmeric, Radix Angelicae Sinensis, Psoralea corylifolia, hairyvein agrimony, Cordyceps sinensis, glossy ganoderma, three
7th, gingko, picria fel tarrae are crushed, and are sieved, and are well mixed and are obtained fermentation raw material；Second step, bacterial classification is added in fermentation raw material, is stirred
Mix the uniform rear fermentation tank that loads to be fermented；3rd step, at 33～40 DEG C, ferments 8～12 days, and low temperature is carried at 20～60 DEG C
Take, obtain moist powder；4th step, adds auxiliary material, makes pharmaceutically acceptable preparation.
In the second step, the bacterial classification is honey or probio.
In the second step, honey is 1～2 with the part by weight of fermentation raw material：1, the weight of probio and fermentation raw material
Ratio is 0.05～0.1:1.
The probio is one or two in lactic acid bacteria, Bifidobacterium, saccharomycete.
In 3rd step, at 37 DEG C, ferment 10 days, low temperature is extracted at 45 DEG C, obtains moist powder.
The invention further relates to application of the Chinese medicine composition in treatment lung-cancer medicament is prepared.
, wherein it is desired to explanation, for the purpose of the present invention is realized, the Chinese medicine composition of the present invention is not limited to
Above-mentioned preparation method, present invention only provides a kind of specific preparation method.
Chinese medicine composition of the present invention, the taxol contained in selected bark of Ramulus et folium taxi cuspidatae has unique antitumor work
With, can suppress cell division, prevent cancer cell multiplication；Red ginseng, with raising body immunity, antifatigue, radioresistance, suppression
Effect of tumour, adjustment human endocrine system；Radix Glycyrrhizae, with invigorating the spleen and benefiting qi, moisten the lung and relieve the cough, relieving spasm to stop pain, coordinating the drug actions of a prescription etc.
Many effects, modern medicine study shows, the effects such as Radix Glycyrrhizae has antiviral, anti-inflammatory；Vomiting nut, with dredging collateral, strong muscle,
The effects such as dissipating bind, pain relieving, detumescence, removing toxic substances；The tuber of pinellia, cures mainly eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, with antineoplastic work
With；The Radix Astragali, sweet, slightly warm in nature, return lung, spleen, liver and kidney channel, the solid table of polishing, torr sore myogenic cures mainly body void spontaneous perspiration, chronic diarrhea, prolapse of the anus,
The prolapse of uterus, chronic nephritis, body void edema, chronic ulcer is most basic for improving lung and respiratory system immunocompetence
Medicinal material；The dried venom of toads, with antibechic, antitumor and antiinflammatory action；Root tuber of aromatic turmeric, with promoting blood circulation and stopping pain, promoting qi circulation and removing obstruction in the collateral, the cool blood that clears away heart-fire, cholagogic
Effect of removing jaundice；Radix Angelicae Sinensis, with the effect of benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation, anticancer, anti-ageing anti-old, immunity；Psoralen
Fat, with tonifying kidney and strengthening yang, astringent sperm contracting urine, lumbago due to the kidney deficiency, frequent urination, infantile enuresis, kidney leakage is warming spleen and stopping diarrha, receives what gas was relievingd asthma
Effect；Hairyvein agrimony, with the effects such as internal heat anticance, cooling blood and hemostasis；Cordyceps sinensis, damages, beneficial vital essence, relieving cough and reducing sputum with qi-restoratives
Effect, cure mainly phlegm and retained fluid breathe heavily cough, the illness such as void is breathed heavily, consumptive disease is coughed, spit blood, spontaneous sweating, impotence and seminal emission, soreness of waist and knee joint；Glossy ganoderma, can mend
Gas calms the nerves, relieving cough and asthma, cures mainly dizziness egersis, palpitation, neurasthenia, consumptive disease cough and asthma, has functions that to promote longevity；Three
Seven, for treat spitting of blood, haematemesis, bleeding from five sense organs or subcutaneous tissue, have blood in stool, uterine bleeding, traumatism and bleeding, chest and abdomen shouting pain, the illness such as tumbling and swelling.Gingko, can
Control asthma, phlegm cough, leukorrhea, gonorrhoea, seminal emission, pulmonary tuberculosis, and there is restraining and sterilizing bacteria；Picria fel tarrae, it is bitter, cold in nature, have
It is clearing heat and detoxicating, the effect of swelling and pain relieving.
Chinese medicine composition of the present invention, including bark of Ramulus et folium taxi cuspidatae, red ginseng, Radix Glycyrrhizae, vomiting nut, the tuber of pinellia, the Radix Astragali, the dried venom of toads,
Root tuber of aromatic turmeric, Radix Angelicae Sinensis, Psoralea corylifolia, hairyvein agrimony, Cordyceps sinensis, glossy ganoderma, pseudo-ginseng, gingko, picria fel tarrae, above-mentioned Chinese medicine complements each other, mutually
Coordinate, can play effect of beneficial gas righting, detoxicating and fighting cancer, treat lung cancer effect is significant, at the same the Chinese medicine of the present invention into
Lease making crosses solid state fermentation, and by macromolecular small molecule is become, and can be absorbed by the body with 100%；Using solid state fermentation, the medicine for obtaining
Active ingredient is improved, and clinical efficacy improves notable.
Specific embodiment
In order that the objects, technical solutions and advantages of the present invention become more apparent, below in conjunction with specific embodiment pair
The present invention is further described.It should be appreciated that specific embodiment described herein is only to explain the present invention, but and
It is not used in the restriction present invention.
Embodiment 1
The first step, weighs bark of Ramulus et folium taxi cuspidatae 10g, red ginseng 8g, Radix Glycyrrhizae 10g, vomiting nut 8g, tuber of pinellia 10g, Radix Astragali 10g, the dried venom of toads
10g, root tuber of aromatic turmeric 30g, Radix Angelicae Sinensis 10g, Psoralea corylifolia 5g, hairyvein agrimony 10g, Cordyceps sinensis 8g, glossy ganoderma 5g, pseudo-ginseng 10g, gingko 10g, hardship are profound
Ginseng 5g, crushes, and sieves, and is well mixed and obtains fermentation raw material；Second step, honey 159g is added in fermentation raw material, and stirring is equal
Load fermentation tank after even to be fermented；3rd step, at 33 DEG C, ferments 12 days, and low temperature is extracted at 20 DEG C, obtains moist powder；
4th step, moist powder is dried, and adds starch, makes pill.
Embodiment 2
The first step, weighs bark of Ramulus et folium taxi cuspidatae 36g, red ginseng 28g, Radix Glycyrrhizae 10g, vomiting nut 28g, tuber of pinellia 36g, Radix Astragali 40g, the dried venom of toads
40g, root tuber of aromatic turmeric 60g, Radix Angelicae Sinensis 40g, Psoralea corylifolia 25g, hairyvein agrimony 30g, Cordyceps sinensis 28g, glossy ganoderma 20g, pseudo-ginseng 35g, gingko 40g,
Picria fel tarrae 20g, crushes, and sieves, and is well mixed and obtains fermentation raw material；Second step, honey 750g is added in fermentation raw material, is stirred
Mix the uniform rear fermentation tank that loads to be fermented；At 35 DEG C, ferment 11 days, low temperature is extracted at 35 DEG C, obtains moist powder；4th
Step, moist powder is dried, and adds dextrin, compressing tablet to make tablet.
Embodiment 3
The first step, weighs bark of Ramulus et folium taxi cuspidatae 23g, red ginseng 18g, Radix Glycyrrhizae 23g, vomiting nut 18g, tuber of pinellia 23g, Radix Astragali 25g, the dried venom of toads
25g, root tuber of aromatic turmeric 45g, Radix Angelicae Sinensis 25g, Psoralea corylifolia 15g, hairyvein agrimony 20g, Cordyceps sinensis 18g, glossy ganoderma 12g, pseudo-ginseng 22g, gingko 25g,
Picria fel tarrae 12g, crushes, and sieves, and is well mixed and obtains fermentation raw material；Second step, honey 698g is added in fermentation raw material, is stirred
It is fitted in fermentation tank after mixing uniformly and is fermented；3rd step, at 37 DEG C, ferments 10 days, extracts at 40 DEG C, obtains moist powder
End；4th step, adds dextrin, and granule is made in drying of pelletizing, packing.
Embodiment 4
The first step, weighs bark of Ramulus et folium taxi cuspidatae 22g, red ginseng 16g, Radix Glycyrrhizae 22g, vomiting nut 16g, tuber of pinellia 22g, Radix Astragali 22g, the dried venom of toads
22g, root tuber of aromatic turmeric 40g, Radix Angelicae Sinensis 22g, Psoralea corylifolia 12g, hairyvein agrimony 18g, Cordyceps sinensis 15g, glossy ganoderma 10g, pseudo-ginseng 20g, gingko 22g,
Picria fel tarrae 10g, crushes, and sieves, and is well mixed and obtains fermentation raw material；Second step, honey 500g is added in fermentation raw material, is stirred
It is fitted in fermentation tank after mixing uniformly and is fermented；3rd step, at 37 DEG C, ferments 10 days, extracts at 45 DEG C, obtains moist powder
End；4th step, moist powder is dried, and adds starch, makes pill.
Embodiment 5
The first step, weighs bark of Ramulus et folium taxi cuspidatae 28g, red ginseng 20g, Radix Glycyrrhizae 25g, vomiting nut 20g, tuber of pinellia 28g, Radix Astragali 27g, the dried venom of toads
27g, root tuber of aromatic turmeric 50g, Radix Angelicae Sinensis 27g, Psoralea corylifolia 18g, hairyvein agrimony 22g, Cordyceps sinensis 20g, glossy ganoderma 15g, pseudo-ginseng 25g, gingko 27g,
Picria fel tarrae 14g, crushes, and sieves, and is well mixed and obtains fermentation raw material；Second step, honey 400g is added in fermentation raw material and is stirred
It is fitted in fermentation tank after mixing uniformly and is fermented；3rd step, at 40 DEG C, ferments 8 days, extracts at 55 DEG C and obtains moist powder；
4th step, moist powder is dried, and adds starch, makes powder.
Embodiment 6
The first step, weighs bark of Ramulus et folium taxi cuspidatae 28g, red ginseng 18g, Radix Glycyrrhizae 24g, vomiting nut 18g, tuber of pinellia 25g, Radix Astragali 25g, the dried venom of toads
24g, root tuber of aromatic turmeric 45g, Radix Angelicae Sinensis 24g, Psoralea corylifolia 15g, hairyvein agrimony 20g, Cordyceps sinensis 17g, glossy ganoderma 13g, pseudo-ginseng 25g, gingko 25g,
Picria fel tarrae 12g, crushes, and sieves, and is well mixed and obtains fermentation raw material；Second step, honey 450g is added in fermentation raw material, is stirred
It is fitted in fermentation tank after mixing uniformly and is fermented；3rd step, at 40 DEG C, ferments 9 days, and 60 DEG C of extractions obtain moist powder；The
Four steps, moist powder is dried, and adds dextrin, compressing tablet to make tablet.
Embodiment 7
The first step, weighs bark of Ramulus et folium taxi cuspidatae 23g, red ginseng 20g, Radix Glycyrrhizae 22g, vomiting nut 18g, tuber of pinellia 24g, Radix Astragali 25g, the dried venom of toads
26g, root tuber of aromatic turmeric 46g, Radix Angelicae Sinensis 28g, Psoralea corylifolia 13g, hairyvein agrimony 24g, Cordyceps sinensis 19g, glossy ganoderma 13g, pseudo-ginseng 22g, gingko 24g,
Picria fel tarrae 13g, crushes, and sieves, and is well mixed and obtains fermentation raw material；Second step, honey 360g is added in fermentation raw material, is stirred
It is fitted in fermentation tank after mixing uniformly and is fermented；3rd step, at 37 DEG C, ferments 10 days, extracts at 50 DEG C and obtains moist powder；
4th step, moist powder is dried, and adds dextrin, compressing tablet to make tablet.
Embodiment 8
The first step, weighs bark of Ramulus et folium taxi cuspidatae 22g, red ginseng 16g, Radix Glycyrrhizae 22g, vomiting nut 16g, tuber of pinellia 22g, Radix Astragali 22g, the dried venom of toads
22g, root tuber of aromatic turmeric 40g, Radix Angelicae Sinensis 22g, Psoralea corylifolia 12g, hairyvein agrimony 18g, Cordyceps sinensis 15g, glossy ganoderma 10g, pseudo-ginseng 20g, gingko 22g,
Picria fel tarrae 10g, crushes, and sieves, and is well mixed and obtains fermentation raw material；Second step, honey 350g is added in fermentation raw material, is stirred
It is fitted in fermentation tank after mixing uniformly and is fermented；3rd step, at 38 DEG C, ferments 9 days, obtains moist powder；4th step, by tide
Wet powder is dried, filling dress capsule, makes capsule.
In embodiment 1-8, using honey as strain raw material, the addition of honey can improve Chinese medicine taste.
Embodiment 9
The first step, weighs bark of Ramulus et folium taxi cuspidatae 23g, red ginseng 20g, Radix Glycyrrhizae 22g, vomiting nut 18g, tuber of pinellia 24g, Radix Astragali 25g, the dried venom of toads
26g, root tuber of aromatic turmeric 46g, Radix Angelicae Sinensis 28g, Psoralea corylifolia 13g, hairyvein agrimony 24g, Cordyceps sinensis 19g, glossy ganoderma 13g, pseudo-ginseng 22g, gingko 24g,
Picria fel tarrae 13g, crushes, and sieves, and is well mixed and obtains fermentation raw material；Second step, 18g lactic acid bacterias are added in fermentation raw material,
It is fitted in fermentation tank after stirring and is fermented；3rd step, at 37 DEG C, ferments 10 days, extracts at 50 DEG C and obtains moist powder
End；4th step, moist powder is dried, and adds dextrin, compressing tablet to make tablet.
Embodiment 10
The first step, weighs bark of Ramulus et folium taxi cuspidatae 22g, red ginseng 16g, Radix Glycyrrhizae 22g, vomiting nut 16g, tuber of pinellia 22g, Radix Astragali 22g, the dried venom of toads
22g, root tuber of aromatic turmeric 40g, Radix Angelicae Sinensis 22g, Psoralea corylifolia 12g, hairyvein agrimony 18g, Cordyceps sinensis 15g, glossy ganoderma 10g, pseudo-ginseng 20g, gingko 22g,
Picria fel tarrae 10g, crushes, and sieves, and is well mixed and obtains fermentation raw material；Second step, by 24.88g saccharomycete fermentation raw material is added to
In, it is fitted in fermentation tank after stirring and is fermented；3rd step, at 38 DEG C, ferments 9 days, obtains moist powder；4th
Step, moist powder is dried, filling dress capsule, makes capsule.
Embodiment 11
The first step, weighs bark of Ramulus et folium taxi cuspidatae 23g, red ginseng 18g, Radix Glycyrrhizae 23g, vomiting nut 18g, tuber of pinellia 23g, Radix Astragali 25g, the dried venom of toads
25g, root tuber of aromatic turmeric 45g, Radix Angelicae Sinensis 25g, Psoralea corylifolia 15g, hairyvein agrimony 20g, Cordyceps sinensis 18g, glossy ganoderma 12g, pseudo-ginseng 22g, gingko 25g,
Picria fel tarrae 12g, crushes, and sieves, and is well mixed and obtains fermentation raw material；Second step, lactic acid bacteria, the common 34.9g of Bifidobacterium are added
To in fermentation raw material, it is fitted in fermentation tank after stirring and is fermented；3rd step, at 37 DEG C, ferments 10 days, carries at 40 DEG C
Take, obtain moist powder；4th step, adds dextrin, and granule is made in drying of pelletizing, packing.
Instructions of taking：All kinds of medicament instructions of taking are as follows in the present invention：Tablet and pill：Twice daily, one after each meal, often
Secondary two panels, every 0.5 gram of content of dispersion；Capsule：Twice daily, one after each meal, two every time, every 0.5 gram of content of dispersion；Dissipate
Agent：Twice daily, one after each meal, each takes a bag, often comprising dose 0.5g；Granule：Twice daily, one after each meal, often
It is secondary to take two, every content of dispersion 0.5g.The four Monday courses for the treatment of, take the course for the treatment of and adjust according to the state of an illness.
Clinical case
Case 1, female, 53 years old, Patients with Lung CT was shown in bottom right lung neoplasm block 3cm × 4cm, took 2 treatments of medicine of embodiment two
Cheng Hou, check CT are shown in that lung tumors reduce soon 60%.
Case 2, female, 56 years old, patient's cough, uncomfortable in chest, weak, lung CT is shown in upper right lobe of the lung central type carcinoma of lung, lump 5cm ×
5cm, after taking 4 courses for the treatment of of medicine of embodiment three, check CT is shown in that pulmonary masses reduce 50%, patient experiences stable disease.
Case 3, man, 57 years old, patient's cough and asthma, uncomfortable in chest, shortness of breath and fatigue, lung CT was shown in upper right lobe of the lung central type carcinoma of lung, lump 5cm
× 7cm, after the cycle of chemotherapy 2, starts to take the medicine in example IV, after taking five courses for the treatment of, checks lung CT mass reductions
30%, drug administration 2 years, survive 36 months, after die from hepatic metastases.
Case 4, man, 47 years old, patient's cough, uncomfortable in chest, the expectoration band trace of blood, lung CT is shown in left lobe central type carcinoma of lung, lump
4cm × 5cm, takes the medicine in embodiment 5, and after taking 4 courses for the treatment of, check CT is shown in that pulmonary masses disappear substantially, takes at present
1 year, patient experiences stable disease.
According to clinical statisticses, totally 169 patients take the Chinese medicine composition of the treatment lung cancer of the present invention, through certain hour
Treatment, cures 25, and therapeutic effect is obvious 75, treats effective 59, and invalid 10, total effective rate is 94%.It is many
Number patient is taken after the Chinese medicine obtained by the present invention, and symptom is obviously improved, and achieves preferable therapeutic effect.
Equally according to clinical verification, patient takes other embodiments of the invention formulation also with same therapeutic effect.
In sum, the Chinese medicine composition for treating liver cancer of the invention has effective inhibitory action, curative effect to lung cancer
Significantly, and without obvious toxic-side effects.
Description of the invention is not exhaustively or limits the invention to disclosed form.Wherein many modifications and
Change is for the ordinary skill in the art obvious, before without departing from the technical scheme described in claim
Put also other deformations.
Claims (10)
1. a kind of Chinese medicine composition, it is characterised in that including the raw material of following weight portion：10～36 parts of bark of Ramulus et folium taxi cuspidatae, red ginseng 8～
28 parts, 10～36 parts of Radix Glycyrrhizae, 8～28 parts of vomiting nut, 10～36 parts of the tuber of pinellia, 10～40 parts of the Radix Astragali, 10～40 parts of the dried venom of toads, root tuber of aromatic turmeric 30
～60 parts, 10～40 parts of Radix Angelicae Sinensis, 5～25 parts of Psoralea corylifolia, 10～30 parts of hairyvein agrimony, 8～28 parts of Cordyceps sinensis, 5～20 parts of glossy ganoderma,
10～35 parts of pseudo-ginseng, 10～40 parts of gingko, 5～25 parts of picria fel tarrae.
2. Chinese medicine composition according to claim 1, it is characterised in that including the raw material of following weight portion：Bark of Ramulus et folium taxi cuspidatae
22～28 parts, 16～20 parts of red ginseng, 22～25 parts of Radix Glycyrrhizae, 16～20 parts of vomiting nut, 22～28 parts of the tuber of pinellia, 22～27 parts of the Radix Astragali,
22～27 parts of the dried venom of toads, 40～50 parts of root tuber of aromatic turmeric, 22～27 parts of Radix Angelicae Sinensis, 12～18 parts of Psoralea corylifolia, 18～22 parts of hairyvein agrimony, Cordyceps sinensis
15～20 parts, 10～15 parts of glossy ganoderma, 20～25 parts of pseudo-ginseng, 22～27 parts of gingko, 10～14 parts of picria fel tarrae.
3. Chinese medicine composition according to claim 2, it is characterised in that the weight proportion of each raw material is：Chinese yew
23 parts of skin, 18 parts of red ginseng, 23 parts of Radix Glycyrrhizae, 18 parts of vomiting nut, 23 parts of the tuber of pinellia, 25 parts of the Radix Astragali, 25 parts of the dried venom of toads, 45 parts of root tuber of aromatic turmeric, Radix Angelicae Sinensis
25 parts, 15 parts of Psoralea corylifolia, 20 parts of hairyvein agrimony, 18 parts of Cordyceps sinensis, 12 parts of glossy ganoderma, 22 parts of pseudo-ginseng, 25 parts of gingko, picria fel tarrae 12
Part.
4. the Chinese medicine composition according to claim 1-3 any one, it is characterised in that the Chinese medicine composition makes medicine
Acceptable preparation on.
5. Chinese medicine composition according to claim 4, it is characterised in that the preparation is tablet, capsule, granule, dissipates
Any one in agent or pill.
6. the preparation method of Chinese medicine composition described in a kind of claim 4, it is characterised in that comprise the steps：The first step, presses
Weight portion weighs bark of Ramulus et folium taxi cuspidatae, red ginseng, Radix Glycyrrhizae, vomiting nut, the tuber of pinellia, the Radix Astragali, the dried venom of toads, root tuber of aromatic turmeric, Radix Angelicae Sinensis, Psoralea corylifolia, hairyvein agrimony, winter
Worm summer grass, glossy ganoderma, pseudo-ginseng, gingko, picria fel tarrae are crushed, and are sieved, and are well mixed and are obtained fermentation raw material；Second step, bacterial classification is added
To in fermentation raw material, fermentation tank is loaded after stirring and is fermented；3rd step, at 33～40 DEG C, ferments 8～12 days, and 20
Low temperature is extracted at～60 DEG C, obtains moist powder；4th step, adds pharmaceutic adjuvant, makes pharmaceutically acceptable preparation.
7. the preparation method of Chinese medicine composition according to claim 6, it is characterised in that in second step, the bacterial classification is honeybee
Honey or probio.
8. the preparation method of Chinese medicine composition according to claim 7, it is characterised in that the weight of the honey and fermentation raw material
Amount ratio is 1～2：1, the probio is 0.05～0.1 with the part by weight of fermentation raw material:1.
9. the preparation method of Chinese medicine composition according to claim 6, it is characterised in that in the 3rd step, at 37 DEG C,
Fermentation 10 days, low temperature is extracted at 45 DEG C, obtains moist powder.
10. application of the arbitrary Chinese medicine composition of claims 1 to 3 in treatment lung-cancer medicament is prepared.
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| CN110537684A (en) * | 2019-04-23 | 2019-12-06 | 辽宁抗风竤生物医药科技有限责任公司 | Dietary therapy composition for treating lung cancer and preparation method thereof |
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|---|---|---|---|---|
| CN1879850A (en) * | 2006-05-06 | 2006-12-20 | 安徽科创中药天然药物研究所有限责任公司 | Capsule with hairy vein agrimony and arenobufagin, its preparation process and quality control method |
| CN102579967A (en) * | 2011-01-14 | 2012-07-18 | 天津市中宝制药有限公司 | Traditional Chinese medicinal composition for treating lung cancer |
| CN103908475A (en) * | 2014-03-26 | 2014-07-09 | 深圳市新华南方生物科技股份有限公司 | Traditional Chinese medicine preparation method |
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2016
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1879850A (en) * | 2006-05-06 | 2006-12-20 | 安徽科创中药天然药物研究所有限责任公司 | Capsule with hairy vein agrimony and arenobufagin, its preparation process and quality control method |
| CN102579967A (en) * | 2011-01-14 | 2012-07-18 | 天津市中宝制药有限公司 | Traditional Chinese medicinal composition for treating lung cancer |
| CN103908475A (en) * | 2014-03-26 | 2014-07-09 | 深圳市新华南方生物科技股份有限公司 | Traditional Chinese medicine preparation method |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110537684A (en) * | 2019-04-23 | 2019-12-06 | 辽宁抗风竤生物医药科技有限责任公司 | Dietary therapy composition for treating lung cancer and preparation method thereof |
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Application publication date: 20170510 |