CN103007241B - Medicament for treating silicosis - Google Patents

Medicament for treating silicosis Download PDF

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Publication number
CN103007241B
CN103007241B CN201310000361.1A CN201310000361A CN103007241B CN 103007241 B CN103007241 B CN 103007241B CN 201310000361 A CN201310000361 A CN 201310000361A CN 103007241 B CN103007241 B CN 103007241B
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parts
radix
herba
medicament
silicosis
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CN201310000361.1A
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CN103007241A (en
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陈光宴
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Abstract

The invention relates to a medicament for treating silicosis, which is prepared from the following bulk pharmaceutical components in parts by weight: 4-8 parts of dried gingers, 6-10 parts of rabdosia rubescens, 1-5 parts of licorice roots, 1-3 parts of euphorbia kansui, 1-5 parts of eucommia barks, 3-6 parts of astragalus roots, 1-5 parts of solidago virgaurea, 10-15 parts of divaricate saposhnikovia roots, 3-7 parts of indian trum etflower seeds, 10-20 parts of rhizoma ligustici wallichii, 3-6 parts of radix stemonae, 10-15 parts of herba orostachyos, 4-8 parts of radix sophorae flavescentis, 1-5 parts of cortex moutan, 1-3 parts of radix ophiopogonis and 3-7 parts of asarum. The medicament for treating silicosis disclosed by the invention is simple in prescription, low in price, clear in curative effect, strong in patient adaptability, and suitable for clinical large-scale promotion.

Description

A kind of medicament for the treatment of anthraco-silicosis
Technical field
The present invention relates to Respiratory Medicine field, specifically, relate to a kind of medicament for the treatment of anthraco-silicosis.
Background technology
Anthraco-silicosis is due to the long-term caused pneumoconiosis of rock dirt containing crystal type free silicon dioxide in a large number that suck.Silicotic generally in early days can be asymptomatic or symptom is not obvious, and along with pathological development, symptom increases, and main manifestations is as follows: (one) cough, expectoration be because dust stimulation and respiratory inflammation are coughed, or have reflex cough.The degree of cough and amount of expectoration number closely related with bronchitis or pulmonary's secondary infection, but also inconsistent with pneumosilicosis lesion degree.Small number of patients can have bloody sputum.If any repeatedly spitting blood in a large number, should consider to merge tuberculosis or bronchiectasis.(2) chest pain 40%~60% patient has acupuncture sample chest pain.Multidigit is in the one or both sides of middle and upper part, shirtfront, irrelevant with breathing, position and work, while being everlasting overcast and rainy and climate variability, occurs.(3) degree uncomfortable in chest, out of breath is relevant with extent of disease and character.Pathological changes is extensively fast with progress, out of breath obvious, and the aggravation of carrying out property.This is due to the extensive fibrosis of lung tissue, alveolar considerable damage, bronchial stenosis and pleural thickening and adhesion, the result that causes ventilation and ventilatory to damage.Patient Shang Ke has giddy, weak, cardiopalmus, stomach poor appetite the symptom such as to move back.The medicine of developing a kind of determined curative effect, convenient and practical treatment anthraco-silicosis is becoming inevitable.
Summary of the invention
The object of this invention is to provide a kind of medicament for the treatment of anthraco-silicosis.
In order to realize method of the present invention, the invention provides a kind of medicament for the treatment of anthraco-silicosis, it is to be made up according to weight portion of following raw material medicaments: 3~7 parts of 4~8 parts of Rhizoma Zingiberiss, 6~10 parts of Rabdosia rubescens, 1~5 part, Radix Glycyrrhizae, 1~3 part of Radix Kansui, 1~5 part of the Cortex Eucommiae, 3~6 parts of the Radixs Astragali, 1~5 part of Herba Solidaginis, 10~15 parts of Radix Saposhnikoviaes, 3~7 parts of Semen Oroxylis, 10~20 parts of Rhizoma Chuanxiongs, 3~6 parts of the Radixs Stemonae, 10~15 parts of Herba Orostachyos, 4~8 parts of Radix Sophorae Flavescentiss, 1~5 part of Cortex Moutan, 1~3 part of Radix Ophiopogonis and Herba Asaris.
Preferably, the medicament for the treatment of anthraco-silicosis of the present invention is to be made up according to weight portion of following raw material medicaments: 6 parts of 7 parts of Rhizoma Zingiberiss, 8 parts of Rabdosia rubescens, 3 parts, Radix Glycyrrhizae, 2 parts of Radix Kansuis, 2 parts of the Cortexs Eucommiae, 4 parts of the Radixs Astragali, 4 parts of Herba Solidaginiss, 11 parts of Radix Saposhnikoviaes, 6 parts of Semen Oroxylis, 17 parts of Rhizoma Chuanxiongs, 5 parts of the Radixs Stemonae, 13 parts of Herba Orostachyos, 7 parts of Radix Sophorae Flavescentiss, 2 parts of Cortex Moutans, 2 parts of Radix Ophiopogonis and Herba Asaris.
Preferably, described medicament is tablet, buccal tablet, instant or decoction.
The medicament prescription for the treatment of anthraco-silicosis of the present invention is simple, is common Chinese medicine, low price, and curative effect is clear and definite, and patient adaptability is strong, is suitable for large-scale popularization clinically.
The specific embodiment
Below the invention will be further described for the description by the specific embodiment, but this is not limitation of the present invention, those skilled in the art are according to basic thought of the present invention, can make various modifications or improvement, but only otherwise depart from basic thought of the present invention, all within the scope of the present invention.
Embodiment 1
Take 60 grams of 70 grams of Rhizoma Zingiberiss, 80 grams of Rabdosia rubescens, 30 grams, Radix Glycyrrhizae, 20 grams of Radix Kansuis, 20 grams of the Cortexs Eucommiae, 40 grams of the Radixs Astragali, 40 grams of Herba Solidaginiss, 110 grams of Radix Saposhnikoviaes, 60 grams of Semen Oroxylis, 170 grams of Rhizoma Chuanxiongs, 50 grams of the Radixs Stemonae, 130 grams of Herba Orostachyos, 70 grams of Radix Sophorae Flavescentiss, 20 grams of Cortex Moutans, 20 grams of Radix Ophiopogonis and Herba Asaris, add 2500 milliliters, water, in sealed container, at 70 ℃, heat 3 hours, be cooled to room temperature.Filter, filtrate is decoction of the present invention.
Experimental example
Diagnostic criteria
China has announced " pneumoconiosis diagnosis standard and treatment principle " in December, 1986, wherein X-ray Diagnosis of Pneumoconiosis standard, be applicable to the legal various pneumoconiosis of country, specific standards is as follows: 1. without pneumoconiosis (code name 0) (1) 0 performance of the x-ray without pneumoconiosis.(2) performance of 0+X line is still diagnosed as " I " person not.2. first phase pneumoconiosis (code name I).(1) I has the little shade of similar round of 1 grade of closeness, and distribution at least respectively has a place in Liang Gefei district, and every place diameter is not less than 2cm; Or having the irregular small opacities of 1 grade of closeness, its distribution is no less than Liang Gefei district.(2) the little shade showed increased of I+, but in closeness and distribution, have one to be still decided to be not " II " person.3. the second stage of pneumoconiosis (code name II) (1) II has similar round or the irregular small opacities of 2 grades of closenesses, and distribution exceedes Si Gefei district; Or having the little shade of 3 grades of closenesses, distribution reaches Si Gefei district.(2) to have closeness be the little shade of 3 grades to II+, and its distribution exceedes Si Gefei district; Or there is large shade still not for " III " person.4. three phase pneumoconiosis (code name III), III has large shade to occur, and its major diameter is not less than 2cm, and wide footpath is not less than 1cm.The area of the single large shade of III+ or the summation of multiple large shaded areas exceed right upper lung district area person.
30 routine patients all make a definite diagnosis after diagnosing.Wherein I phases 16 example, II phases 8 example, III phases 6 example.Merge pulmonary tuberculosis 10 examples; Emphysema, the lung heart 14 examples, pneumothorax 1 example.Year mean age 60.8 (51-72).All have the symptoms such as cough, expectoration, chest discomfort, 16 examples have the symptoms such as the heart that degree is different is tired, gas is tight, two lower limbs edema, 4 example spitting of bloods (or sputum mixed with blood).
Use the decoction of preparation in embodiment 1 to treat.Every day three times, each oral 300 milliliters, treat continuously 9 months.
Criterion of therapeutical effect
Effective: the symptoms such as cough, expectoration, the heart tire out, gas is tight obviously alleviate, and lower limbs edema disappears, and heart merit is normal.Effective: the symptoms such as cough, expectoration, the heart is tired, gas is tight, lower limbs edema alleviate, heart merit II-III level.Invalid: before and after treatment, nothing changes.
Therapeutic outcome
Before treatment, compared with after treatment, wherein effective 25 examples, account for 83.33%, and effective 5 examples, account for 16.67%.Total effective rate is 100%.

Claims (2)

1. treat a decoction for anthraco-silicosis, it is characterized in that it is to be made up according to weight portion of following raw material medicaments: 3~7 parts of 4~8 parts of Rhizoma Zingiberiss, 6~10 parts of Rabdosia rubescens, 1~5 part, Radix Glycyrrhizae, 1~3 part of Radix Kansui, 1~5 part of the Cortex Eucommiae, 3~6 parts of the Radixs Astragali, 1~5 part of Herba Solidaginis, 10~15 parts of Radix Saposhnikoviaes, 3~7 parts of Semen Oroxylis, 10~20 parts of Rhizoma Chuanxiongs, 3~6 parts of the Radixs Stemonae, 10~15 parts of Herba Orostachyos, 4~8 parts of Radix Sophorae Flavescentiss, 1~5 part of Cortex Moutan, 1~3 part of Radix Ophiopogonis and Herba Asaris.
2. the decoction for the treatment of anthraco-silicosis according to claim 1, is characterized in that it is to be made up according to weight portion of following raw material medicaments: 6 parts of 7 parts of Rhizoma Zingiberiss, 8 parts of Rabdosia rubescens, 3 parts, Radix Glycyrrhizae, 2 parts of Radix Kansuis, 2 parts of the Cortexs Eucommiae, 4 parts of the Radixs Astragali, 4 parts of Herba Solidaginiss, 11 parts of Radix Saposhnikoviaes, 6 parts of Semen Oroxylis, 17 parts of Rhizoma Chuanxiongs, 5 parts of the Radixs Stemonae, 13 parts of Herba Orostachyos, 7 parts of Radix Sophorae Flavescentiss, 2 parts of Cortex Moutans, 2 parts of Radix Ophiopogonis and Herba Asaris.
CN201310000361.1A 2013-01-04 2013-01-04 Medicament for treating silicosis Expired - Fee Related CN103007241B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105362750A (en) * 2015-11-25 2016-03-02 赵连祺 Traditional Chinese medicine preparation for treating pulmonary silicosis and preparation method of traditional Chinese medicine preparation for treating pulmonary silicosis

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1127121A (en) * 1995-01-20 1996-07-24 杨贵森 Xiaozhoutian (small circulation in Qigong) external curing heath care band and use method
CN1049597C (en) * 1996-06-11 2000-02-23 王来运 Liquid medicine for treatment of tracheitis and preparing method thereof
CN102579967A (en) * 2011-01-14 2012-07-18 天津市中宝制药有限公司 Traditional Chinese medicinal composition for treating lung cancer

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1127121A (en) * 1995-01-20 1996-07-24 杨贵森 Xiaozhoutian (small circulation in Qigong) external curing heath care band and use method
CN1049597C (en) * 1996-06-11 2000-02-23 王来运 Liquid medicine for treatment of tracheitis and preparing method thereof
CN102579967A (en) * 2011-01-14 2012-07-18 天津市中宝制药有限公司 Traditional Chinese medicinal composition for treating lung cancer

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