CN102579590A - Drug for treating knee osteoarthritis (OA) - Google Patents
Drug for treating knee osteoarthritis (OA) Download PDFInfo
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- CN102579590A CN102579590A CN2012100465071A CN201210046507A CN102579590A CN 102579590 A CN102579590 A CN 102579590A CN 2012100465071 A CN2012100465071 A CN 2012100465071A CN 201210046507 A CN201210046507 A CN 201210046507A CN 102579590 A CN102579590 A CN 102579590A
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Abstract
The invention discloses a drug for treating knee osteoarthritis (OA), aiming to overcome the defects of the prior art. The drug is prepared from the following components: 100g of linum oil, 30g of fructus cannabis oil, 30g of pine needle oil and 30g of clove oil, wherein the above components are mixed uniformly to prepare mixed oil and the mixed oil is filled into a disinfectant glass drug bottle for later use. When the drug is used, 6mg of the mixed oil drug is drawn with a disposable sterile needle, the knee of the patient is disinfected and the mixed oil drug is injected into the joint cavity of the patient.
Description
Technical field the invention belongs to technical field of Chinese medicines, relates to a kind of medicine of treating knee joint osseous arthritis, is the Chinese medicine oil preparation of feedstock production specifically with the Chinese herbal medicine.
Background technology knee joint osseous arthritis (knee joint OA) is person in middle and old age's common diseases, and the course of disease is long, and is painful big, outbreak repeatedly.The cause of disease more complicated that this is sick comprises mechanics and biochemical factor, it is generally acknowledged with to increase multiple factors such as age, wound, endocrine, cartilage metabolism, dysimmunity and heredity relevant, and pathological characteristic is that articular cartilage degeneration, erosion, destruction and hyperosteogeny form.Therapeutic Method commonly used at present has local injection procaine and hydrocortisone acetate, oral naproxen, indometacin etc., but effect is not satisfactory.This serious harm healthy elder.Motherland's medical science thinks that this disease belongs to " arthromyodynia " category, and etiology and pathogenesis is old deficiency of kidney-QI, wind, cold, damp invasion and attack, retardance meridians, stagnation of QI and blood may bring about pain.Chinese medicine use advantage at tool aspect the treatment " arthromyodynia ", thus invent that a kind of medicine of treating knee joint osseous arthritis treats should disease.
Summary of the invention the purpose of this invention is to provide a kind of medicine of treating knee joint osseous arthritis, to overcome the deficiency of prior art.
The objective of the invention is with reference to modern pharmacological research, therefrom to filter out natural Chinese medicinal herb oil,, it is played a role by the theory of Chinese medical science prescription according to the pathogenetic understanding and the Therapeutic Principle thereof of motherland's medical tradition medical science to knee joint osseous arthritis.
Medicine of the present invention is processed by following component:
Pockmarks core oil 100 gram Fructus Cannabis oil 30 gram pinke needle oil 30 gram Oleum Caryophyllis 30 grams
Above-mentioned each component mix homogeneously is become miscible oil, subsequent use in the disinfectant glass medicine bottle of packing into.During use, extract 6 milligrams of miscible oil medicines of the present invention,, miscible oil medicine of the present invention is injected in patient's the articular cavity the sterilization of patient's knee joint with disposable sterilized pin, the 6 milligrams of miscible oil medicines of the present invention that reinject after 10 days, five months is a course of treatment.
Medicine of the present invention is the Chinese medicine oil preparation, according to theory of Chinese medical science, select medicine rationally, topical, treating both the principal and secondary aspects of a disease.Medicine of the present invention, warp is the clinical observation patient for many years, and evident in efficacy, the knee joint osseous arthritis patient that a variety of causes is caused has remarkable result.
Clinical drug of the present invention is taken the result and is shown, following advantage is arranged:
It is raw oil that the present invention selects natural plant for use, and each component meets the pharmaceutical control law regulation, utilizes the comprehensive function treatment knee joint osseous arthritis of the medicine of respectively distinguishing the flavor of, and no chemicals is harmless to human non-toxic, has no side effect, and is safe and reliable.The present invention is an oil preparation, topical, and curative effect is high, and is cheap, no any discomfort disease.
For showing the therapeutic effect of medicine of the present invention to knee joint osseous arthritis; The present invention is through the clinical observation of 400 routine knee joint osseous arthritis patient systems; And select medical history, the state of an illness, age and knee joint osseous arthritis patient 400 examples suitable to organize as a comparison with traditional therapy; Age 40-86 year, course of disease 1-20; Test group: use medicine of the present invention; Matched group: use routine medication.Observation period is 5 months, check after 5 months.Efficacy assessment standard adopts in People's Republic of China's Chinese medicine industry standard in 2005 " disease of tcm diagnosis criterion of therapeutical effect ".Cure: knee joint swelling, pain complete obiteration, knee joint movable function is normal.Effectively: knee joint swelling disappears, and swelling pain alleviates, the overworked pain that still has, and knee joint function is normal basically.Do not heal: swelling shows effect repeatedly, and the gonalgia is not alleviated.
Drug use method of the present invention; Extract 6 milligrams of miscible oil medicines of the present invention with disposable sterilized pin,, miscible oil medicine of the present invention is injected in patient's the articular cavity the sterilization of patient's knee joint; The 6 milligrams of miscible oil medicines of the present invention that reinject after 10 days, five months is a course of treatment.Clinical comparison result sees table 1.
Table 1: use medicine of the present invention with the observation of curative effect of conventional treatments to the knee joint osseous arthritis patient.
Two groups of curative effects comparisons of table 1 (example, %)
Annotate: curative effect relatively adopts statistical method, and enumeration data adopts X
2Check, two groups of effective percentage compare P＜0.01
Can find out that from table 1 two groups of effective percentage compare: the experimental group total effective rate is 100%, and matched group is 50%, and experimental group obviously is superior to matched group (P＜0.01), explains that medicine of the present invention has significant therapeutical effect.
The specific embodiment
Choose raw material by following proportioning:
Pockmarks core oil 100 gram Fructus Cannabis oil 30 gram pinke needle oil 30 gram Oleum Caryophyllis 30 grams
Above-mentioned each component mix homogeneously is become miscible oil, subsequent use in the disinfectant glass medicine bottle of packing into.During use, extract 6 milligrams of miscible oil medicines of the present invention,, miscible oil medicine of the present invention is injected in patient's the articular cavity the sterilization of patient's knee joint with disposable sterilized pin, the 6 milligrams of miscible oil medicines of the present invention that reinject after 10 days, five months is a course of treatment.
Claims (1)
1. a medicine of treating knee joint osseous arthritis is the oil preparation of being processed by the following weight proportion raw material: choose raw material by following proportioning: pockmarks core oil 100 gram Fructus Cannabis oil 30 gram pinke needle oil 30 gram Oleum Caryophyllis 30 grams; Above-mentioned each component mix homogeneously is become miscible oil.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012100465071A CN102579590A (en) | 2012-02-18 | 2012-02-18 | Drug for treating knee osteoarthritis (OA) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012100465071A CN102579590A (en) | 2012-02-18 | 2012-02-18 | Drug for treating knee osteoarthritis (OA) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102579590A true CN102579590A (en) | 2012-07-18 |
Family
ID=46469192
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012100465071A Pending CN102579590A (en) | 2012-02-18 | 2012-02-18 | Drug for treating knee osteoarthritis (OA) |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102579590A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002085394A1 (en) * | 2001-04-24 | 2002-10-31 | Bakulesh Mafatlal Khamar | The process of preparing the topical anti-inflammatory/analgesic preparation |
| US20030165588A1 (en) * | 2002-03-01 | 2003-09-04 | Unigen Pharmaceuticals, Inc. | Identification of free-B-ring flavonoids as potent COX-2 inhibitors |
| WO2003092599A2 (en) * | 2002-04-30 | 2003-11-13 | Unigen Pharmaceuticals, Inc. | Formulation of a mixture of free-b-ring flavonoids and flavans as a therapeutic agent |
| US20090087501A1 (en) * | 2007-10-01 | 2009-04-02 | Colgate-Palmolive Company | Oral Compositions Containing Botanical Extracts |
| US20110245333A1 (en) * | 2002-03-01 | 2011-10-06 | Unigen, Inc. | Identification of free-b-ring flavonoids as potent cox-2 inhibitors |
-
2012
- 2012-02-18 CN CN2012100465071A patent/CN102579590A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002085394A1 (en) * | 2001-04-24 | 2002-10-31 | Bakulesh Mafatlal Khamar | The process of preparing the topical anti-inflammatory/analgesic preparation |
| US20030165588A1 (en) * | 2002-03-01 | 2003-09-04 | Unigen Pharmaceuticals, Inc. | Identification of free-B-ring flavonoids as potent COX-2 inhibitors |
| US20110245333A1 (en) * | 2002-03-01 | 2011-10-06 | Unigen, Inc. | Identification of free-b-ring flavonoids as potent cox-2 inhibitors |
| WO2003092599A2 (en) * | 2002-04-30 | 2003-11-13 | Unigen Pharmaceuticals, Inc. | Formulation of a mixture of free-b-ring flavonoids and flavans as a therapeutic agent |
| US20090087501A1 (en) * | 2007-10-01 | 2009-04-02 | Colgate-Palmolive Company | Oral Compositions Containing Botanical Extracts |
Non-Patent Citations (2)
| Title |
|---|
| S. IRAVANI, ET AL.: "Pharmaceutical and nutraceutical effects of Pinus pinaster bark extract", 《RES PHARM SCI》 * |
| 黄晨七: "中药内服、熏洗治疗膝关节骨关节炎60例临床分析", 《中外医疗》 * |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20120718 |