CN102579280B - Anti-acne skin lotion - Google Patents
Anti-acne skin lotion Download PDFInfo
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- CN102579280B CN102579280B CN 201210059731 CN201210059731A CN102579280B CN 102579280 B CN102579280 B CN 102579280B CN 201210059731 CN201210059731 CN 201210059731 CN 201210059731 A CN201210059731 A CN 201210059731A CN 102579280 B CN102579280 B CN 102579280B
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Abstract
The invention belongs to the technical field of daily use chemical products, in particular to an anti-acne skin lotion. In a formula of the anti-acne skin lotion, a vitamin C liposome is adopted instead of vitamin C or vitamin C phosphate, so that the defect of brown discoloration of the vitamin C phosphate is overcome, and a solution is stable. Meanwhile, as proved by detection, the anti-bacterial effect of propionibacterium acnes can be enhanced by over two times by combining the vitamin C liposome with sodium salicylate.
Description
Technical field
The invention belongs to the daily chemical products technical field, be specifically related to a kind of anti-acne milky lotion.
Background technology
Acne is a kind of common pilosebaceous unit dermatosis, is characteristics with non-inflammation acne and how serious form, for example struvite pimple, pustule and joint knot etc.
Conventional medicament is different to the safety and the curative effect of acne treatment, and normally result enough can't be realized patient's expection.Common acne treatment effective ingredient is normally with tretinoin, antibiotic, and perhaps benzoyl peroxide is the basis, adopts antibiotic to reduce the probability that propionibacterium acnes occurs.But there is some adverse consequences in above-mentioned prior art, may cause red swelling of the skin and burn feeling as benzoyl peroxide, and the skin lightsensitivity increase that the cutaneous pigmentation change causes may occur.
A commercially available major types in addition is that Chinese medicine extract carries out the development of daily use chemicals exterior-applied article as effective ingredient, and such cosmetics of everyday use is difficult to determine because of its concrete effective ingredient, therefore is unable to estimate its side effect, has bigger risk.
Chinese patent literature CN101426468 discloses a kind of cosmetic composition that comprises salicylic acid and ascorbic acid, points out that the combination of salicylic acid and ascorbic acid can effectively suppress propionibacterium acnes; Chinese patent literature CN 101631593 discloses being combined with of nicotiamide, biotin and ascorbic acid and has been beneficial to the recrystallization that reduces biotin.
The ascorbic acid that above-mentioned prior art is used all refers to ascorbic acid phosphate, the problem of unstable, easy variable color that its aqueous solution exists, skin absorbs difference.
Summary of the invention
The present invention is directed to above-mentioned the deficiencies in the prior art, a kind of anti-acne milky lotion is provided, the different phase that can form at acne is effectively brought into play curative effect, and pigmentation is had curative effect, and its skin utilization rate improves greatly, and ambient-temp-stable can reach more than 2 years.
Concrete technical scheme of the present invention is:
A kind of anti-acne milky lotion is characterized in that the weight percentages of components of this milky lotion is:
The A phase: methyl hydroxybenzoate 0.2%, HANSHENGJIAO 0.2%, glycerol 5%, sodium salicylate 1%-2%,
The B phase: ceteareth-60 myristyl glycol 2%, mineral oil 10%, glyceryl stearate 1%, polydimethylsiloxane 1%, laureth-11 0.5%, propyl hydroxybenzoate 0.15%,
The C phase: emulsifing thickener 2%,
The D phase: essence 0.8%, dihydroxymethyl glycolylurea 0.25%, vitamin C liposome 0.5%-2%,
Surplus is a water,
A mutually is heated to 80 ℃ respectively mutually with water and B, stir down A is added to B mutually in, homogenizing adds the C phase after being cooled to 60 ℃, be cooled to 40 ℃ after adding D phase.
Described A mutually in the sodium salicylate percentage by weight be 1%, the vitamin C liposome percentage by weight of D in mutually is 2%.
Described A mutually in the sodium salicylate percentage by weight be 2%, the vitamin C liposome percentage by weight of D in mutually is 1%.
Described A mutually in the sodium salicylate percentage by weight be 1%, the vitamin C liposome percentage by weight of D in mutually is 0.5%.
Wherein: ceteareth-60 myristyl glycol, English full name CETEARETH-60 MYRISTYL GLYCOL, CAS 96081-39-9.
The present invention substitutes vitamin C or vitamin C phosphate with vitamin C liposome, overcome the puzzlement of the brown variable color of vitamin C phosphate, solution-stabilized, simultaneously, surprised discovery, the fungistatic effect that the compatibility of vitamin C liposome and sodium salicylate can improve propionibacterium acnes reaches more than the twice.
The specific embodiment
Embodiment 1
A kind of anti-acne milky lotion, its weight percentages of components is:
The A phase: methyl hydroxybenzoate 0.2%, HANSHENGJIAO 0.2%, glycerol 5%, sodium salicylate 1%,
The B phase: ceteareth-60 myristyl glycol 2%, mineral oil 10%, glyceryl stearate 1%, polydimethylsiloxane 1%, laureth-11 0.5%, propyl hydroxybenzoate 0.15%,
The C phase: emulsifing thickener 2%,
The D phase: essence 0.8%, dihydroxymethyl glycolylurea 0.25%, vitamin C liposome 2%,
Surplus is a water,
With A mutually and water and B heat phase to 80 ℃, stir down A is added to B mutually in, homogenizing adds the C phase after being cooled to 60 ℃, be cooled to 40 ℃ after adding D phase.
The experiment proved that the milky lotion transdermal characteristic the best under this ratio.
Embodiment 2
A kind of anti-acne milky lotion, its weight percentages of components is:
The A phase: methyl hydroxybenzoate 0.2%, HANSHENGJIAO 0.2%, glycerol 5%, sodium salicylate 2%,
The B phase: ceteareth-60 myristyl glycol 2%, mineral oil 10%, glyceryl stearate 1%, polydimethylsiloxane 1%, laureth-11 0.5%, propyl hydroxybenzoate 0.15%,
The C phase: emulsifing thickener 2%,
The D phase: essence 0.8%, dihydroxymethyl glycolylurea 0.25%, vitamin C liposome 1%,
Surplus is a water,
With A mutually and water and B heat phase to 80 ℃, stir down A is added to B mutually in, homogenizing adds the C phase after being cooled to 60 ℃, be cooled to 40 ℃ after adding D phase.
Embodiment 3
A kind of anti-acne milky lotion, its weight percentages of components is:
The A phase: methyl hydroxybenzoate 0.2%, HANSHENGJIAO 0.2%, glycerol 5%, sodium salicylate 1%,
The B phase: ceteareth-60 myristyl glycol 2%, mineral oil 10%, glyceryl stearate 1%, polydimethylsiloxane 1%, laureth-11 0.5%, propyl hydroxybenzoate 0.15%,
The C phase: emulsifing thickener 2%,
The D phase: essence 0.8%, dihydroxymethyl glycolylurea 0.25%, vitamin C liposome 1%,
Surplus is a water,
With A mutually and water and B heat phase to 80 ℃, stir down A is added to B mutually in, homogenizing adds the C phase after being cooled to 60 ℃, be cooled to 40 ℃ after adding D phase.
Embodiment 4
A kind of anti-acne milky lotion, its weight percentages of components is:
The A phase: methyl hydroxybenzoate 0.2%, HANSHENGJIAO 0.2%, glycerol 5%, sodium salicylate 2%,
The B phase: ceteareth-60 myristyl glycol 2%, mineral oil 10%, glyceryl stearate 1%, polydimethylsiloxane 1%, laureth-11 0.5%, propyl hydroxybenzoate 0.15%,
The C phase: emulsifing thickener 2%,
The D phase: essence 0.8%, dihydroxymethyl glycolylurea 0.25%, vitamin C liposome 0.5%,
Surplus is a water,
With A mutually and water and B heat phase to 80 ℃, stir down A is added to B mutually in, homogenizing adds the C phase after being cooled to 60 ℃, be cooled to 40 ℃ after adding D phase.
Claims (4)
1. anti-acne milky lotion is characterized in that the weight percentages of components of this milky lotion is:
The A phase: methyl hydroxybenzoate 0.2%, HANSHENGJIAO 0.2%, glycerol 5%, sodium salicylate 1%-2%,
The B phase: ceteareth-60 myristyl glycol 2%, mineral oil 10%, glyceryl stearate 1%, polydimethylsiloxane 1%, laureth-11 0.5%, propyl hydroxybenzoate 0.15%,
The C phase: emulsifing thickener 2%,
The D phase: essence 0.8%, dihydroxymethyl glycolylurea 0.25%, vitamin C liposome 0.5%-2%,
Surplus is a water,
A mutually is heated to 80 ℃ respectively mutually with water and B, stir down A is added to B mutually in, homogenizing adds the C phase after being cooled to 60 ℃, be cooled to 40 ℃ after adding D phase.
2. anti-acne milky lotion according to claim 1 is characterized in that the sodium salicylate percentage by weight is 1% during described A mutually, and the vitamin C liposome percentage by weight of D in mutually is 2%.
3. anti-acne milky lotion according to claim 1 is characterized in that the sodium salicylate percentage by weight is 2% during described A mutually, and the vitamin C liposome percentage by weight of D in mutually is 1%.
4. anti-acne milky lotion according to claim 1 is characterized in that the sodium salicylate percentage by weight is 1% during described A mutually, and the vitamin C liposome percentage by weight of D in mutually is 0.5%.
Priority Applications (1)
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CN 201210059731 CN102579280B (en) | 2012-03-08 | 2012-03-08 | Anti-acne skin lotion |
Applications Claiming Priority (1)
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CN 201210059731 CN102579280B (en) | 2012-03-08 | 2012-03-08 | Anti-acne skin lotion |
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CN102579280A CN102579280A (en) | 2012-07-18 |
CN102579280B true CN102579280B (en) | 2013-07-31 |
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CN 201210059731 Expired - Fee Related CN102579280B (en) | 2012-03-08 | 2012-03-08 | Anti-acne skin lotion |
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Families Citing this family (1)
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JP2016525128A (en) * | 2013-07-22 | 2016-08-22 | ザ プロクター アンド ギャンブル カンパニー | How to protect your skin from environmental stressors |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0709082A2 (en) * | 1994-10-28 | 1996-05-01 | Beiersdorf Aktiengesellschaft | Combinations of active ingredients based on wool wax acids and glycerides of saturated fatty acids efficient against impure skin, slight forms of acne as well as propionibacterium acnes |
CN1965791A (en) * | 2006-11-07 | 2007-05-23 | 华南农业大学 | Anti-acne moisturizing cream and preparation process thereof |
CN101426468A (en) * | 2006-04-18 | 2009-05-06 | 帝斯曼知识产权资产管理有限公司 | Cosmetic compositions comprising salicylic acid and ascorbic acid |
CN102232912A (en) * | 2010-04-24 | 2011-11-09 | 王洪 | Inflammation eliminating and sebum removing skin cleaning lotion |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001039848A (en) * | 1999-07-27 | 2001-02-13 | Kao Corp | Skin lotion |
KR101274811B1 (en) * | 2006-02-08 | 2013-06-13 | 주식회사 엘지생활건강 | Potent anti-acne composition containing perilla frutescens and/or lygodium japonicum extract |
-
2012
- 2012-03-08 CN CN 201210059731 patent/CN102579280B/en not_active Expired - Fee Related
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0709082A2 (en) * | 1994-10-28 | 1996-05-01 | Beiersdorf Aktiengesellschaft | Combinations of active ingredients based on wool wax acids and glycerides of saturated fatty acids efficient against impure skin, slight forms of acne as well as propionibacterium acnes |
CN101426468A (en) * | 2006-04-18 | 2009-05-06 | 帝斯曼知识产权资产管理有限公司 | Cosmetic compositions comprising salicylic acid and ascorbic acid |
CN1965791A (en) * | 2006-11-07 | 2007-05-23 | 华南农业大学 | Anti-acne moisturizing cream and preparation process thereof |
CN102232912A (en) * | 2010-04-24 | 2011-11-09 | 王洪 | Inflammation eliminating and sebum removing skin cleaning lotion |
Non-Patent Citations (4)
Title |
---|
JP特开2001-39848A 2001.02.13 |
刘玮,等.祛斑面膜贴液.《皮肤科学与化妆品功效评价》.化学工业出版社,2005,第329页. * |
赵丽.乳液.《美容化妆品学》.2005,第99-100页. * |
陈婷婷.维生素C脂质体的研究.《中国学术文献网络出版总库》.2008,摘要,正文第7-12页. * |
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