CN102578100B - Antifungal composition - Google Patents
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- CN102578100B CN102578100B CN 201210012335 CN201210012335A CN102578100B CN 102578100 B CN102578100 B CN 102578100B CN 201210012335 CN201210012335 CN 201210012335 CN 201210012335 A CN201210012335 A CN 201210012335A CN 102578100 B CN102578100 B CN 102578100B
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Abstract
The invention discloses an antifungal composition which contains the following compounds that achieve synergy as active constituents: a constituent A is selected from azole compounds shown in the formula (I); and a constituent B is selected from the compounds with antifungal activity or salts thereof, such as triazoles, thiocarbamates, methoxyl acrylates, carbamates, antibiotics and amides. The definitions of groups in the formula are expressed in an instruction book. The weight ratio between A and B in the composition is 1:200-200:1.
Description
Technical field
The present invention is dividing an application of Chinese patent application (application number 200710175628.5, October 9 2007 applying date).
The invention belongs to the disinfectant use in agriculture field, relate to a kind of Fungicidal composition particularly.
Background technology
Reported a kind of substituted azole compounds among Chinese invention patent CN1657524A and the PCT application WO2005080344A1, this compounds is for the good control efficiency of disease fungus, to cereal, paddy rice, fruit tree, plurality of plant diseases on the crops such as vegetables is for example to rice blast, false smut, rice sheath blight disease, sclerotinia rot of colza, the tomato leaf mildew, the tomato gray mold, ring rot of apple, apple valsa canker, melon anthracnose, cucumber fusarium axysporum, cucumber downy mildew, powdery mildew of cucumber, cotton verticillium wilt, cotton wilt, fungal diseases such as wheat powdery mildew all have the better prevention effect.
This compounds is the mitochondrial respiratory inhibitor.Because it is very single to suppress mitochondrial electronics transfer function site, germ produces adaptive variation to medicament easily, may cause the preventive effect of medicament to reduce even invalid, and this type of medicament is existing drug-fast relevant report in Europe.Actual agriculture experience also shows, long-term repeat and single-mindedly use a kind of reactive compound and prevent and treat the fast selective that harmful fungoid can cause fungal bacterial strain under many circumstances, described bacterial strain develops innately or the resistance that adapts to particular active compounds, causes re-using described reactive compound and effectively prevents and treats these fungies.Therefore people pay special attention to this class problem.
Summary of the invention
Optionally dangerous in order to reduce the resistance fungal bacterial strain, use the mixture of different activities compound to prevent and treat harmful fungoid usually.Make up by the compound that will have the different mechanisms of action, effectively preventing influences the harmful fungoid of plant growth more, prolongs the service life of each component in the mixture.The present invention aims to provide a kind of Fungicidal composition that contains the different activities compound and have synergistic function, with the purpose that reaches effective processing resistance and effectively prevent and treat plant pathogenic fungi.
Technical scheme of the present invention is as follows:
The invention provides a kind of Fungicidal composition, the following compound that comprises Synergistic is selected from substituted azole compounds or its salt shown in general formula (I) as active component: component A:
In the formula:
X
1Be selected from CH or N, X
2Be selected from O, S or NR
7, X
3Be selected from O, S or NR
8
A
1Be selected from N or CR
9, A
2Be selected from N or CR
10, A
3Be selected from N or CR
11, A wherein
1, A
2, A
3The number that is selected from N simultaneously less than, equal 1;
R
1, R
2Can be identical or different, be selected from hydrogen, C respectively
1-C
12Alkyl or halo C
1-C
12Alkyl;
R
3Be selected from hydrogen, halogen atom, C
1-C
12Alkyl, halo C
1-C
12Alkyl or C
1-C
12Alkoxyl;
R
7Be selected from hydrogen or C
1-C
12Alkyl;
R
8Be selected from hydrogen, C
1-C
12Alkyl, halo C
1-C
12Alkyl, C
1-C
12Alkoxy carbonyl or C
1-C
12Alkoxy carbonyl C
1-C
12Alkyl;
R
4, R
5, R
6, R
9, R
10, R
11Can be identical or different, be selected from hydrogen, halogen atom, nitro, cyano group, CONH respectively
2, CH
2CONH
2, CH
2CN, C
1-C
12Alkyl, halo C
1-C
12Alkyl, C
1-C
12Alkoxyl, halo C
1-C
12Alkoxyl, C
1-C
12Alkylthio group, C
1-C
12Alkane sulfonyl, C
1-C
12Alkyl-carbonyl, C
1-C
12Alkoxy C
1-C
12Alkyl, C
1-C
12Alkoxy carbonyl, C
1-C
12Alkoxy carbonyl C
1-C
12Alkyl, C
1-C
12Halogenated alkoxy C
1-C
12Alkyl, the following groups that can replace arbitrarily: amido C
1-C
12Alkyl, aryl, heteroaryl, aryloxy group, aryl C
1-C
12Alkyl, fragrant C
1-C
12Alkyl oxy, heteroaryl C
1-C
12Alkyl or heteroaryl C
1-C
12Alkoxyl; And stereoisomer.
B component is selected from acceptable isomers or its salt on six compounds as described below artificial synthetic or that derive from natural products with Fungicidally active and their agricultural:
Triazole class compounds (B
1), for example fluorine ring azoles, triazolone, Difenoconazole, alkene azoles alcohol, nitrile bacterium azoles, Tebuconazole, propiconazole, prothioconazoles, oxygen ring azoles, bromuconazole, Cyproconazole, Difenoconazole, efficient alkene azoles alcohol, RH-7592, Flusilazole, Flutriafol, own azoles alcohol, glyoxalin, kind bacterium azoles, metconazole, penconazole, simeconazoles, tetraconazole, Triadimenol, triticonazole, bitertanol, tricyclazole.
Thiocarbamate compounds (B
2), for example mancozeb, maneb, zineb, Propineb, ambam, tmtd, ziram.
Methoxy acrylic ester compounds (B
3), for example Fluoxastrobin, fluoxastrobin, oxime bacterium ester, ZEN 90160, pyraclostrobin, ether bacterium amine, kresoxim-methyl, SSF 126, orysastrobin, Enestroburin (SYP-Z071), alkene oxime amine (SYP-1620), ZJ0712, UBF-307, KZ165.
Carbamate compound (B
4), for example mould prestige of second, iprovalicarb, benzene metsulfovax, valiphenal (IR5885), Propamocarb, methasulfocarb, pyribencarb, meptyldinocap.
Antibiotics compound (B
5), for example blasticidin-S, kasugarnycin, myxothiazol, polyoxin, Polyoxin, pseudomycin, PSF-D, valida, jinggangmeisu, streptomycin.
Amides compound (B
6), for example flumorph, dimethomorph, thiophene fluorine bacterium amine, ring propionyl bacterium amine, fenhexamid, zarilamid, isotianil, silicon metsulfovax, furan pyrrole bacterium amine, zoxamide, metalaxyl, furalaxyl, M 9834, two chlorine zarilamid, flusulfamide.
Weight ratio between A, B two components is 1: 200～200: 1.
In the Fungicidal composition of the present invention more preferably technical scheme be:
Component A is selected from the substituted azole compounds shown in the general formula (I) or its salt:
In the formula:
X
1Be selected from CH, X
2Be selected from O, X
3Be selected from NCH
3
A
1, A
3Be selected from CH respectively, A
2Be selected from C-Cl;
R
1, R
2Be selected from CH respectively
3, R
3Be selected from hydrogen, R
4, R
5, R
6Be selected from hydrogen respectively; Structure is as follows:
The azoles bacterium ester Chinese general by name of compound (1), chemical name is:
(E)-2-(2-((3-(4-chlorphenyl)-1-methyl isophthalic acid H-pyrazoles-5-base oxygen base) methyl) phenyl)-3-methoxy-methyl acrylate
[(E)-methyl?2-(2-((3-(4-chlorophenyl)-1-methyl-1H-pyrazol-5-yloxy)methyl)phenyl)-3-methoxyacrylate]。
The more preferably compound of B component is selected from:
Triazole class compounds (B
1) comprising: (2) fluorine ring azoles (epoxiconazole), (3) triazolone (triadimefon), (4) Difenoconazole (difenoconazole), (5) alkene azoles alcohol (diniconazole), (6) nitrile bacterium azoles (myclobutanil), (7) propiconazole (propiconazole) or (8) Tebuconazole (tebuconazole);
Thiocarbamate compounds (B
2) comprising: (9) mancozeb (mancozeb), (10) maneb (maneb), (11) zineb (zineb), (12) Propineb (propineb), (13) ambam (amobam), (14) tmtd (thiram) or (15) ziram (ziram);
Methoxy acrylic ester compounds (B
3) comprising: (16) Fluoxastrobin (azoxystrobin), (17) oxime bacterium ester (trifloxystrobin), (18) ZEN 90160 (picoxystrobin), (19) pyraclostrobin (pyraclostrobin) or (20) ether bacterium amine (dimoxystrobin);
Carbamate compound (B
4) comprising: the mould prestige of (21) second (diethofencarb), (22) iprovalicarb (iprovalicarb), (23) benzene metsulfovax (benthiavalicarb-isopropyl), (24) methasulfocarb (methasulfocarb) or (25) Propamocarb (propamocarb);
Antibiotics compound (B
5) comprising: (26) blasticidin-S (blasticidin-S), (27) kasugarnycin (kasugamycin), (28) polyoxin (polyoxins) or (29) Polyoxin (polyoxorim).
Amides compound (B
6) comprising: (30) flumorph (flumorph), (31) dimethomorph (Dimethomorph).
Above-mentioned B component composition is the control medicament commonly used of various crop disease, in long-term use, shown good control efficiency, it is described in detail sees " The Pesticide Manual " (12th ed UK:BCPC, 2000), " The Pesticide Manual " (13th ed UK:BCPC, 2003).
In the composition A, B two components more preferably weight ratio be 1: 100～100: 1; More preferably 1: 50～50: 1.
Further optimized technical scheme is:
Component A is selected from (E)-2-(2-((3-(4-chlorphenyl)-1-methyl isophthalic acid H-pyrazoles-5-base oxygen base) methyl) phenyl)-3-methoxy-methyl acrylate; B component is selected from fluorine ring azoles, triazolone, Difenoconazole, alkene azoles alcohol, nitrile bacterium azoles, propiconazole or Tebuconazole; Weight ratio in the composition between A, B two components is 1: 40～40: 1.
Perhaps, component A is selected from (E)-2-(2-((3-(4-chlorphenyl)-1-methyl isophthalic acid H-pyrazoles-5-base oxygen base) methyl) phenyl)-3-methoxy-methyl acrylate; B component is selected from mancozeb, maneb, zineb, Propineb, ambam, tmtd or ziram; Weight ratio in the composition between A, B two components is 1: 20～20: 1.
Perhaps, component A is selected from (E)-2-(2-((3-(4-chlorphenyl)-1-methyl isophthalic acid H-pyrazoles-5-base oxygen base) methyl) phenyl)-3-methoxy-methyl acrylate; B component is selected from Fluoxastrobin, oxime bacterium ester, ZEN 90160, pyraclostrobin or ether bacterium amine; Weight ratio in the composition between A, B two components is 1: 20～20: 1.
Perhaps, component A is selected from (E)-2-(2-((3-(4-chlorphenyl)-1-methyl isophthalic acid H-pyrazoles-5-base oxygen base) methyl) phenyl)-3-methoxy-methyl acrylate; B component is selected from the mould prestige of second, iprovalicarb, benzene metsulfovax, methasulfocarb or Propamocarb; Weight ratio in the composition between A, B two components is 1: 20～20: 1.
Perhaps, component A is selected from (E)-2-(2-((3-(4-chlorphenyl)-1-methyl isophthalic acid H-pyrazoles-5-base oxygen base) methyl) phenyl)-3-methoxy-methyl acrylate; B component is selected from blasticidin-S, kasugarnycin, polyoxin or Polyoxin; Weight ratio in the composition between A, B two components is 1: 20～20: 1.
Perhaps, component A is selected from (E)-2-(2-((3-(4-chlorphenyl)-1-methyl isophthalic acid H-pyrazoles-5-base oxygen base) methyl) phenyl)-3-methoxy-methyl acrylate; B component is selected from flumorph or dimethomorph; Weight ratio in the composition between A, B two components is 1: 20～20: 1.
Have now found that Fungicidal composition of the present invention has very obvious role in synergism, the control efficiency of corps diseases is significantly increased, can enlarge fungicidal spectrum simultaneously, delay the drug-fast generation of pathogen.Therefore technical scheme of the present invention has comprised the application of controlling plant diseases aspect.
The present composition is suitable for preventing and treating multiple harmful fungoid, the especially multiple diseases of cereal class, vegetables, fruit tree, ornamental plants, lawn and tropical crop, and multiple storage disease.
When the preparation said composition, pure reactive compound (1) and at least a B component composition of preferred use, can be to wherein adding other to harmful pathogen or the effective active substance of other insect, or have reactive compound or the fertilizer of herbicide effect and growth regulating effect.No matter use said composition in any form, be the using of mixture of compound (1) and at least a B component composition independent or co-administered or compound (1) and at least a B component composition, all present and prevent and treat significantly that the disease scope increases and the preventive effect of some disease is improved, comprise the plurality of plant diseases that sac fungi, basidiomycetes, imperfect fungus etc. are caused.Composition is to preventing and treating the fungal disease of various crops such as cereal, paddy rice, vegetables, fruit tree, flowers, and it is particularly important to be used for the seed dressing cover crop.Be particularly suitable for preventing and treating the following plants fungal disease: powdery mildew of cucumber, cucumber downy mildew, gray mold of cucumber, scab of cucumber, muskmelon powdery mildew, soybean rust, tomato gray mold, tomato powdery mildew, watermelon anthrax, rice blast, rice green smut, wheat powdery mildew, wheat rust, pear scab, leaf spot of peanut, powdery mildew of strawberry, sigatoka etc.
According to the occurrence degree of corps diseases, the working concentration of the present composition is 1～1500g/hm in the proportion of crop planting zone
2, preferred 15～400g/hm
2Here the working concentration of compound (1) is 0.02～400g/hm
2, preferred 5～250g/hm
2Accordingly, compound (B
1)～(B
5) working concentration be 0.02～1000g/hm
2, preferred 15～600g/hm
2
Handle kind of a period of the day from 11 p.m. to 1 a.m, the working concentration of composition is generally 1～1000g/kg, preferred 1～800g/kg.
In the process of controlling plant diseases, the using period of composition of the present invention can be before or after the plant seeding, also can be before or after plant emerges mode such as seed, plant or soil spraying or loose powder be carried out.
Fungicidal composition of the present invention can be formulated as direct spray solution, powder, suspension, water-based, oiliness or other suspension, dispersion, emulsion, oil dispersion, paste, the pulvis that highly concentrate, broadcast sowing with mixture or particle, and can be by spraying, atomizing, dusting, broadcast sowing or mode such as topple over and use.Administration form depends on specific purpose; In all cases, should guarantee the meticulous and even distribution of the present composition.
Fungicidal composition of the present invention maybe will be prevented and treated plant corpus, seed, soil, zone, material or the space that they are infected with dosage control harmful fungoid, its habitat that suitable formulation, use are fit to.Using of compound can be carried out before or after harmful fungoid infects, emphasis should be before infecting or the initial stage of infecting use.
Can prepare the preparation of Fungicidal composition of the present invention with known method.At least comprise two kinds of carriers in the composition of the present invention, carrier can be solid or liquid, and any carrier that is generally used for preparing microbicide compositions all can use.At least a carrier is surfactant in the composition, for example can be emulsifier, dispersant or wetting agent etc.Surfactant is commercially available, and its selection is that those skilled in the art are known, for example, and lauryl sodium sulfate, Teepol, neopelex, polyoxyethylene fatty acid fat, polyoxyethylene aliphatic alcohol ether or polyoxyethylene fatty amine etc.
The present composition can be mixed with missible oil, suspending agent, (water) emulsion, wetting powder, (aqueous dispersion) granula etc., and these preparations can be prepared by method in common.In the composition, the active constituent content sum of A, B component is that the weight content of active component is 0.1～95%, preferred 0.1～80%.
Composition of the present invention is that the example (the concrete application is not limited only to this) of several common formulations of being mixed with of active substance is listed below:
One, the product of dilute with water
1.10% aqueous emulsion (EW)
Reactive compound 10%, polyvinyl alcohol 0.8%, alkylaryl polyoxyethylene poly-oxygen propylene aether 8.5%, farming breast 2,201 16%, dimethyl formamide 11%, ethylene glycol 5%, water complements to 100%.
2.20% missible oil (EC)
Reactive compound 20%, agricultural newborn 500#10%, agricultural newborn OX-6355%, methyl alcohol 10%, dimethylbenzene complements to 100%.
3.40% suspending agent (SC)
Reactive compound 40%, calcium lignosulfonate 5%, White Carbon black 0.3%, ethylene glycol 4%, defoamer a little, water complements to 100%.
4.50% water dispersible granules (WG)
Reactive compound 50%, methyl naphthalene sulfonate formaldehyde condensate 12%, epoxidized polyether 5%, soluble starch 15%, gypsum complements to 100%.
5.70% wetting powder (WP)
Reactive compound 70%, lauryl sodium sulfate 1.5%, carboxymethyl cellulose 1%, sodium lignin sulfonate 10%, precipitated calcium carbonate complements to 100%.
Two, the product that can use without dilution
6.5% pulvis (DP)
Fully mix with 5 parts of taskwork compound grindings in small, broken bits and with the kaolin in small, broken bits of 95 parts of weights and to obtain pulvis.
7.0.5% granule (GR)
With 0.5 part of taskwork compound grinding in small, broken bits and in conjunction with the carrier of 99.5 parts of weights, current methods be extrude, atomized drying or fluid bed, obtain the particle that can use without dilution.
The product that the present invention describes provides with the finished product preparation form, and namely each material mixes in the composition.Simultaneously, the composition of composition also separately the form of preparation directly mixing in bucket (jar) before using is provided.Concentrate of the present invention mixes the concentration that obtains required active substance with water usually, by spraying, atomizing, dusting, broadcast sowing or pour into a mould and use.Type of service depends on the purpose that will reach fully, guarantees that in all cases the best of reactive compound of the present invention may distribute.
Moisture type of service can prepare by adding water by emulsion concentrates, paste or wettable powder (sprayable powder, oil dispersion).Be preparation emulsion, paste or oil dispersion, can be by wetting agent, tackifier, dispersant or emulsifier with this material directly or be dissolved in back homogenizing in water in oil or the solvent.Perhaps, can prepare the concentrate that is suitable for dilute with water and is formed by active substance, wetting agent, tackifier, dispersant or emulsifier, solvent or oil.
Various types of oil, wetting agent, adjuvant, weed killer herbicide, fungicide, other agricultural chemicals or bactericide all can add in the reactive compound, if suitable, just add (bucket mixes) before the next-door neighbour uses.These reagent mix with 1: 30～30: 1 weight ratio with mixture of the present invention usually.
Embodiment
Fungicidal composition of the present invention can illustrate by following example the synergistic function of harmful fungoid, but the present invention only limits to this absolutely not.
Reactive compound independent or associating is prepared into acetone or the DMSO liquid storage that contains 0.25% (weight) reactive compound.Emulsifier with 1% (weight)
(BASF AG's product) adds in this liquid storage, and water is with this reactive compound or mixture diluted desired concn to the following example.
Infect percentage evaluation by measuring leaf area.These percentages are changed into effectiveness.Use the Abbot formula to calculate according to following formula and render a service (W):
W＝(1-α/β)×100
α handles the fungal infection percentage of plant;
The be untreated fungal infection percentage of (blank) plant of β.
Render a service to " 0 " and represent that the level that infects of processing plant is identical with the level that infects of untreated control plant; Render a service to " 100 " represent to handle plant and infected.
The expection effectiveness use Colby formula [R.S.Colby, weeds (Weeds) 15,20-22 (1967)] of active compound combinations is determined and is compared with observed effectiveness.
Colby formula: E=x+y-xy/100
E: the expection when working concentration is respectively the mixture of the reactive compound A of a and b and B is renderd a service, and represents with the % of untreated control.
Effectiveness when the x working concentration is the reactive compound A of a is represented with the % of untreated control;
Effectiveness when the y working concentration is the reactive compound B of b is represented with the % of untreated control.
In the following example, employed crop seedling is all planted cultivation in potted plant mode in the greenhouse.Treat growth of seedling to tri-leaf period, the healthy seedling that selects the growth neat and consistent is used for giving birth to test and tests.The mixing ratio of listed A, B two composition activity compounds is weight ratio in each table.
Application Example 1 control wheat powdery mildew test
The potted plant wheat seedling leaf that with cultivar is " distant spring No. 10 " is sprayed to the drip point with activity compound concentration aqueous suspension as described below.Second day, with the spore aqueous suspension inoculation plant of white powder germ (Blumeria graminis).Then test plants is placed 22～24 ℃ to be that 75% climatic chamber is regulated 7 days with relative atmospheric humidity.The development degree of infection process on the leaf is measured in range estimation then.
The reactive compound that table 1 is independent
Table 2 present composition
" * ": the effectiveness of using the Colby formula to calculate.
Application Example 2 is prevented and treated the powdery mildew of cucumber test
Cultivar is sprayed to the drip point for the potted plant cucumber seedling leaf of " the close thorn in Shandong " with activity compound concentration aqueous suspension as described below.Second day, with the spore aqueous suspension inoculation plant of white powder germ (Erysiphe cucurbitacearum).Then test plants is placed 22～24 ℃ to be that 75% climatic chamber is regulated 7 days with relative atmospheric humidity.The development degree of infection process on the leaf is measured in range estimation then.
The reactive compound that table 3 is independent
Table 4 present composition
" * ": the effectiveness of using the Colby formula to calculate.
Application Example 3 control wheat powdery mildew tests
The potted plant wheat seedling leaf that with cultivar is " distant spring No. 10 " is sprayed to the drip point with activity compound concentration aqueous suspension as described below.Second day, with the spore aqueous suspension inoculation plant of white powder germ (Blumeria graminis).Then test plants is placed 22～24 ℃ to be that 75～80% climatic chambers are regulated 8 days with relative atmospheric humidity.The development degree of infection process on the leaf is measured in range estimation then.
The reactive compound that table 5 is independent
Table 6 present composition
" * ": the effectiveness of using the Colby formula to calculate.
Application Example 4 control cucumber downy mildew tests
Cultivar is sprayed to the drip point for the potted plant cucumber seedling leaf of " the close thorn in Shandong " with activity compound concentration aqueous suspension as described below.Second day, with the spore aqueous suspension inoculation plant of Pseudoperonospora cubensis (Pseudoperonospora cubensis).Then test plants is placed 22～24 ℃ to be that 90% climatic chamber is regulated 7 days with relative atmospheric humidity.The development degree of infection process on the leaf is measured in range estimation then.
The reactive compound that table 7 is independent
Table 8 composition of the present invention
" * ": the effectiveness of using the Colby formula to calculate.
Application Example 5 is prevented and treated the wheat scab test
The potted plant wheat wheat head that with cultivar is " distant spring No. ten " is sprayed to the drip point with activity compound concentration aqueous suspension as described below.Second day, with the spore aqueous suspension inoculation plant of gibberellic hypha (Fusarium grammearum).Then test plants is placed 22～24 ℃ to be that 90% climatic chamber is regulated 14 days with relative atmospheric humidity.Naked eyes are measured the development degree of infection process on the wheat head then.
The reactive compound that table 9 is independent
Table 10 composition of the present invention
" * ": the effectiveness of using the Colby formula to calculate.
Application Example 6 control gray mold of cucumber tests
Cultivar is sprayed to the drip point for the potted plant cucumber seedling leaf of " the close thorn in Shandong " with activity compound concentration aqueous suspension as described below.Second day, with the spore aqueous suspension inoculation plant of ash arrhizus bacteria (Botrytis cinerea).Then test plants is placed 22～24 ℃ to be that 95～99% climatic chambers are regulated 7 days with relative atmospheric humidity.Naked eyes are measured the development degree of infection process on the leaf then.
The reactive compound that table 11 is independent
Table 12 composition of the present invention
" * ": the effectiveness of using the Colby formula to calculate.
Application Example 7 control rice blast tests
Cultivar is sprayed to the drip point for the pot rice seedling leaf of " more light " with activity compound concentration aqueous suspension as described below.Second day, with the spore aqueous suspension inoculation plant of Pyricularia oryzae (Pyricularia grisea).Then test plants is placed 24～28 ℃ to be that 95～99% climatic chambers are regulated 5 days with relative atmospheric humidity.Naked eyes are measured the development degree of infection process on the leaf then.
The reactive compound that table 29 is independent
Table 30 composition of the present invention
" * ": the effectiveness of using the Colby formula to calculate.
Application Example 8 control cucumber downy mildew tests
Cultivar is sprayed to the drip point for the potted plant cucumber seedling leaf of " Chang Chun Mi Ci " with activity compound concentration aqueous suspension as described below.Second day, with the spore aqueous suspension inoculation plant of Pseudoperonospora cubensis (Pseudoperonospora cubensis).Then test plants is placed 22～24 ℃ to be that 90% climatic chamber is regulated 7 days with relative atmospheric humidity.The development degree of infection process on the leaf is measured in range estimation then.
The reactive compound that table 31 is independent
Table 32 composition of the present invention
" * ": the effectiveness of using the Colby formula to calculate.
Claims (3)
1. Fungicidal composition, the following compound that comprises Synergistic is selected from (E)-2-(2-((3-(4-chlorphenyl)-1-methyl isophthalic acid H-pyrazoles-5-base oxygen base) methyl) phenyl)-3-methoxy-methyl acrylate as active component: component A, and structural formula is as follows:
B component is selected from methoxy acrylic ester compounds (B
3), described methoxy acrylic ester compounds is selected from Fluoxastrobin, oxime bacterium ester, ZEN 90160 or pyraclostrobin;
Weight ratio in the composition between A, B two components is 1:50～50:1; The weight content of active component is 0.1～95% in the composition.
2. according to the described Fungicidal composition of claim 1, it is characterized in that: the weight ratio in the composition between A, B two components is 1:20～20:1.
According to claim 1 or 2 described Fungicidal compositions in the application aspect the controlling plant diseases.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5869517A (en) * | 1994-07-06 | 1999-02-09 | Basf Aktiengesellschaft | 2- (dihydro)pyrazol-3'-yloxymethylene!anilides, their preparation and their use |
| CN1906171A (en) * | 2004-02-20 | 2007-01-31 | 沈阳化工研究院 | Substituted azole compounds, preparation and application thereof |
-
2007
- 2007-10-09 CN CN 201210012335 patent/CN102578100B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5869517A (en) * | 1994-07-06 | 1999-02-09 | Basf Aktiengesellschaft | 2- (dihydro)pyrazol-3'-yloxymethylene!anilides, their preparation and their use |
| CN1906171A (en) * | 2004-02-20 | 2007-01-31 | 沈阳化工研究院 | Substituted azole compounds, preparation and application thereof |
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