CN102553891A - Method for removing residual pharmaceutical ingredients in oxytetracycline pharmaceutical dregs by ultrasonic wave - Google Patents
Method for removing residual pharmaceutical ingredients in oxytetracycline pharmaceutical dregs by ultrasonic wave Download PDFInfo
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- CN102553891A CN102553891A CN2012100176654A CN201210017665A CN102553891A CN 102553891 A CN102553891 A CN 102553891A CN 2012100176654 A CN2012100176654 A CN 2012100176654A CN 201210017665 A CN201210017665 A CN 201210017665A CN 102553891 A CN102553891 A CN 102553891A
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Abstract
The invention discloses a method for removing residual pharmaceutical ingredients in oxytetracycline pharmaceutical dregs by ultrasonic wave, comprising the following steps of: A, heating up oxytetracycline wet pharmaceutical dregs to solidify protein, so that the protein is not influenced by ultrasonic wave; B, cooling the oxytetracycline wet pharmaceutical dregs into normal temperature, adjusting the pH of the oxytetracycline wet pharmaceutical dregs into 0.5-1.0 by hydrochloric acid, and evenly stirring the wet pharmaceutical dregs; and C, putting the evenly-stirred wet pharmaceutical dregs into a container with normal pressure and ultrasonic environment to carry out ultrasonic wave radiation, and degrading and invalidating the oxytetracycline ingredient in the wet pharmaceutical dregs by the acoustic cavitation effect of the ultrasonic wave. The method is quick, low-cost and environment-friendly to treat the oxytetracycline pharmaceutical dregs, and is good in treatment effect, so that the obtained product is heavy in weight and high in use value.
Description
Technical field
The present invention relates to Resource Recovery of Industrial Solid Waste, minimizing and comprehensive utilization technique field, especially a kind of method of utilizing ultrasonic wave to eliminate left drug composition in the terramycin dregs of a decoction.
Background technology
Terramycin is a kind of broad-spectrum antibiotic, is microbial fermentation product, and to the part gram-positive bacteria, negative bacterium, Richettsia all have stronger bacteriostasis.Terramycin is an amphoteric compound, under acid, alkali condition, all is prone to take place reaction of degeneration (RD).Present domestic terramycin production technology mainly contains fermentation and extracts two parts, and fermentation process will be a raw material with nearly 10 kinds of organic matters such as starch, soya bean muffin, dextrin, as microorganism synthetic carbon source and ability; Extraction process is regulated the pH value for make acidulant of oxalic acid, utilizes potassium ferrocyanide one zinc sulfate to make macromolecule impurities such as the collaborative removal of cleanser protein, filters through flame filter press, removes solid impurity, i.e. the terramycin dregs of a decoction; Filtrating further purifies terramycin filtrating with the 122# resin decolorization, transfers the crystallization of pH to 4.8 left and right sides to obtain the Oxytetracycline Base product at last.Its main component of the terramycin dregs of a decoction is microbial bacteria body cell, undegradable solid organic matters, inorganic salts and residual compositions such as terramycin.Contain each seed amino acid more than 32%, 30%-40% thick protein and various trace elements, satholith mycin 8-9mg/kg.Because the antibiotic composition of residual minim in the dregs of a decoction, the environment event that unorderedly flow, unordered utilization and unordered disposal causes has caused certain influence to the people's productive life, and has caused the extensive concern of various circles of society.2009; General office of Chinese Ministry of Environmental Protection has issued " producing and dispose the notice of special examination about carrying out hazardous wastes such as the antibiotic dregs of a decoction " (ring is done [2009] No. 80); Clear and definite manufacturing enterprise is first owner of hazardous waste pollution prevention, and the prevention and cure of pollution situation of the follow-up storage of the terramycin dregs of a decoction, utilization, disposal overall process is monitored.Because lack effective processing method at present, a large amount of terramycin dregs of a decoction can only take expensive burning mode to handle, a large amount of each seed amino acid, thick protein and various trace elements in the dregs of a decoction also will waste.About 20,000 tons of the annual terramycin output in the whole nation, 1 ton of terramycin of every production produces 4 tons of dregs of a decoction approximately, promptly can produce the terramycin dregs of a decoction about 80,000 tons every year.The dregs of a decoction have taken a large amount of soils and have stored up for a long time, under natural slacking, run off everywhere, and soil is polluted; Solvable composition permeates downwards from the face of land with rainwater, transforms to soil, makes the soil enrichment harmful substance; Or the water that permeates the ground, flow into rivers,lakes and seas, cause the severe contamination of water body; In stacking process, some organic substance decomposes, and produces pernicious gas, causes air pollution.
The method of at present the terramycin dregs of a decoction being handled has two kinds: a kind of is to utilize biotechnology that the antibiotic dregs of a decoction are carried out harmless treatment (200510012998.8), and it comprises medium preparation, inoculation, fermentation.With the main component of the antibiotic dregs of a decoction as culture medium, bacterial classification and culture medium to be inserted carry out the normal pressure anaerobic fermentation in the fermentation tank, fermentation condition is: 24 ℃-28 ℃ of temperature, the pH value is 6.2-6.8, fermentation period is 36-264 hour.Process conditions require high, and process complicacy and cycle are long, and the waste residue that proposes behind the albumen also needs processing.Another kind is to handle with chemical method the terramycin dregs of a decoction are handled (ZL200710185390.4), and the required time is long, hydrochloric acid consumption concentration height, and consumption is big, and processing procedure uses methyl alcohol, unavoidably has the residual of methyl alcohol.So the resource of the terramycin dregs of a decoction, innoxious industrial applications are still problem anxious to be solved at present.
Summary of the invention
The technical problem that the present invention will solve provides a kind of method of utilizing ultrasonic wave to eliminate the left drug composition in the terramycin dregs of a decoction; Can solve the deficiency of prior art; Processing procedure to the terramycin dregs of a decoction is quick, cheap, environmental protection, and treatment effect is good, and the products therefrom huge profit is high with being worth.
For solving the problems of the technologies described above, the technical scheme that the present invention taked is following.
A kind of method of utilizing ultrasonic wave to eliminate left drug composition in the terramycin dregs of a decoction, its step comprises:
A, the wet dregs of a decoction of terramycin are heated to 60 ℃-80 ℃, make it not receive hyperacoustic the influence to solidify protein;
B, the wet dregs of a decoction of terramycin utilize its pH of hydrochloric acid adjusting to be 0.5-1.0 after being cooled to normal temperature, and the dregs of a decoction that will wet stir;
C, the wet dregs of a decoction that will stir are put into the container of normal pressure, ultrasound environments, and under the stable cavitation condition, the control sound intensity is (0.5-10) W/cm
2, supersonic frequency is 20kHz-200kHz; Carry out the ultrasonic wave radiation, utilize hyperacoustic sound cavitation effect to make terramycin composition degraded in the wet dregs of a decoction, lost efficacy, filter then, add basifier the pH value of gained filter residue is adjusted to 4-5, dry or air dry gets final product.
As a kind of optimal technical scheme of the present invention, in the steps A, the wet dregs of a decoction of terramycin are heated to 70 ℃-75 ℃ and be incubated 5min-15min, make it not receive hyperacoustic the influence to solidify protein.
As a kind of optimal technical scheme of the present invention; Among the step B; After the wet dregs of a decoction of terramycin were cooled to normal temperature, by the ratio of the hydrochloric acid 10mL-25mL of the wet dregs of a decoction adding of per 50 gram terramycin 0.4mol/L-0.6mol/L, regulating its pH was 0.5-1.0; The dregs of a decoction obtain dilution simultaneously, and the dregs of a decoction that will wet at last stir.
As a kind of optimal technical scheme of the present invention, among the step C, the duration of ultrasonic wave radiation is 10min-30min.
As a kind of optimal technical scheme of the present invention, among the step C, filter gained filtrating and return step B, substitute part hydrochloric acid as the recycle of pH conditioning agent, realize the refuse zero-emission.
As a kind of optimal technical scheme of the present invention, among the step C, utilize calcium hydroxide or calcium oxide that the pH value of the gained dregs of a decoction is adjusted to 4-5.
Adopt the beneficial effect that technique scheme produced to be:
The present invention adopts supercritical ultrasonics technology to remove the residual drug in the terramycin dregs of a decoction; The cavitation effect of ultrasonic waves that process conditions of the present invention are created; It can produce localized hyperthermia's hyperbaric environment of about 5000K and 100MPa in instant of detonation; And the microjet of the about 110m/s of generation speed with intense impact power, these conditions are enough to make the chemical bond rupture of residual active constituent in the dregs of a decoction and water burning, pyrolytic or radical reaction take place, thereby eliminate residual active ingredient in the dregs of a decoction; And the thick protein in the reservation dregs of a decoction; Make the dregs of a decoction as feed addictive, the entire process process is quick, cheap, environmental protection, and the degradation condition of satholith mycin is gentle, degradation rate is fast, do not have secondary pollution;
Processing method of the present invention adds the ratio of the hydrochloric acid 10mL-25mL of 0.5mol/L in the wet dregs of a decoction of per 50 gram terramycin in step B, regulating its pH is 0.5-1.0; Like this; When regulating dregs of a decoction pH, it has been carried out effective dilution, for follow-up sonicated is got ready;
The wet dregs of a decoction after the sonicated filter the gained filter residue as finished product, and left drug composition has wherein obtained effective elimination, has kept several amino acids, trace element and thick protein; Can be used as safe forage protein uses; Have high industrial or agricultural industrial value, and filter gained filtrating, to wherein adding after higher-purity hydrochloric acid is adjusted to suitable concn with it because of hydrochloric; Promptly can return step B and recycle, realize the refuse zero-emission as the reagent of regulating pH;
The concrete test data that the embodiment that vide infra partly provides is utilized processing method of the present invention, and the clearance of satholith mycin is 90%-100% in the dregs of a decoction, does not have discharge of wastewater; Carry out subchronic toxicity test with mouse to handling the back terramycin dregs of a decoction, confirm that the terramycin dregs of a decoction do not produce noxious material in processing procedure.
The specific embodiment
Following examples have specified the present invention.Various raw material used in the present invention and items of equipment are conventional commercially available prod, all can buy directly through market to obtain.
Embodiment 1
Get the wet dregs of a decoction of 50 gram terramycin and put in the beaker, place water-bath and be heated to 70 ℃-75 ℃ insulation 10min, be cooled to the hydrochloric acid solution 25mL that adds 0.5mol/L after the room temperature, mix, measuring pH is 0.5; The dregs of a decoction that mix are placed in the ultrasonic instrument, are 1W/cm at supersonic frequency 20kHz, the sound intensity
2The time, handle centrifugal filtration behind the 30min, reclaim filtrating and utilizes again as the pH conditioning agent, filter residue is regulated pH value 4.5 with calcium oxide, puts in the drying box dry 30min under 90 ℃; The terramycin dregs of a decoction after being processed are surveyed by " People's Republic of China's veterinary drug allusion quotation " standard in the cooling back, and the mould cellulose content of satholith is reduced to 0.07% by 0.57%, and clearance is 87.7%, and crude protein content drops to 36.9% by 40.3%, reduce 8.4%.
Embodiment 2
Get the wet dregs of a decoction of 50 gram terramycin and put in the beaker, place water-bath and be heated to 70 ℃-75 ℃ insulation 20min, be cooled to the hydrochloric acid solution 20mL that adds 0.5mol/L after the room temperature, mix, measuring pH is 0.6; The dregs of a decoction that mix are placed in the ultrasonic instrument, are 2W/cm at supersonic frequency 40kHz, the sound intensity
2The time, handle centrifugal filtration behind the 10min, reclaim filtrating and utilizes again as the pH conditioning agent, filter residue is regulated pH value 4.5 with calcium oxide, puts in the drying box dry 30min under 90 ℃; The terramycin dregs of a decoction after being processed are surveyed by " People's Republic of China's veterinary drug allusion quotation " standard in the cooling back, and the mould cellulose content of satholith is reduced to 0.055% by 0.57%, and clearance is 90.3%, and crude protein content drops to 36.9% by 40.3%, reduce 8.4%.
Embodiment 3
Get the wet dregs of a decoction of 50 gram terramycin and put in the beaker, place water-bath and be heated to 70 ℃-75 ℃ insulation 10min, be cooled to the hydrochloric acid solution 1mL that adds 0.5mol/L after the room temperature, mix, measuring pH is 0.8; The dregs of a decoction that mix are placed in the ultrasonic instrument, are 3.5W/cm at supersonic frequency 80kHz, the sound intensity
2The time, handle centrifugal filtration behind the 20min, reclaim filtrating and utilizes again as the pH conditioning agent, filter residue is regulated pH value 4.5 with calcium oxide, puts in the drying box dry 30min under 90 ℃; The terramycin dregs of a decoction after being processed are surveyed by " People's Republic of China's veterinary drug allusion quotation " standard in the cooling back, and the mould cellulose content of satholith 0.57% is reduced to 0.06%, and clearance is 89.5%, and crude protein content drops to 36.9% by 40.3%, reduce 8.4%.
Embodiment 4
Get the wet dregs of a decoction of 50 gram terramycin and put in the beaker, place water-bath and be heated to 70 ℃-75 ℃ insulation 10min, be cooled to the hydrochloric acid solution 10mL that adds 0.5mol/L after the room temperature, mix, measuring pH is 1; The dregs of a decoction that mix are placed in the ultrasonic instrument, are 4W/cm at supersonic frequency 120kHz, the sound intensity
2The time, handle centrifugal filtration behind the 10min, reclaim filtrating and utilizes again as the pH conditioning agent, filter residue is regulated pH value 4.5 with calcium oxide, puts in the drying box dry 30min under 90 ℃; The terramycin dregs of a decoction after being processed are surveyed by " People's Republic of China's veterinary drug allusion quotation " standard in the cooling back, and the mould cellulose content of satholith 0.57% is reduced to 0.03%, and clearance is 94.7%, and crude protein content drops to 36.9% by 40.3%, reduce 8.4%.
Embodiment 5
Get the wet dregs of a decoction of 50 gram terramycin and put in the beaker, place water-bath and be heated to 70 ℃-75 ℃ insulation 10min, be cooled to the hydrochloric acid solution 10mL that adds 0.5mol/L after the room temperature, mix, measuring pH is 1; The dregs of a decoction that mix are placed in the ultrasonic instrument, are 5W/cm at supersonic frequency 200kHz, the sound intensity
2The time, handle centrifugal filtration behind the 10min, reclaim filtrating and utilizes again as the pH conditioning agent, filter residue is regulated pH value 4.5 with calcium oxide, puts in the drying box dry 30min under 90 ℃; The terramycin dregs of a decoction after being processed are surveyed by " People's Republic of China's veterinary drug allusion quotation " standard in the cooling back, and the mould cellulose content of satholith 0.57% is reduced to 0.02%, and clearance is 96.5%, and crude protein content drops to 36.9% by 40.3%, reduce 8.4%.
Embodiment 6
Get the wet dregs of a decoction of 50 gram terramycin and put in the beaker, place water-bath and be heated to 70 ℃-75 ℃ insulation 10min, be cooled to the hydrochloric acid solution 10mL that adds 0.5mol/L after the room temperature, mix, measuring pH is 1; The dregs of a decoction that mix are placed in the ultrasonic instrument, are 5W/cm at supersonic frequency 200kHz, the sound intensity
2The time, centrifugal filtration behind the sonicated 10min is reclaimed filtrating and is utilized as the pH conditioning agent again, and filter residue is regulated pH value 4.5 with calcium hydroxide, puts in the drying box at 90 ℃ of following dry 30min; The terramycin dregs of a decoction after being processed are surveyed by " People's Republic of China's veterinary drug allusion quotation " standard in the cooling back, and the mould cellulose content of satholith 0.57% is reduced to 0.025%, and clearance is 95.6%, and crude protein content drops to 36.9% by 40.3%, reduce 8.4%.
Foregoing description only proposes as the enforceable technical scheme of the present invention, not as the single restrictive condition to its technical scheme itself.
Claims (6)
1. method of utilizing ultrasonic wave to eliminate left drug composition in the terramycin dregs of a decoction, its characterization step comprises:
A, the wet dregs of a decoction of terramycin are heated to 60 ℃-80 ℃, make it not receive hyperacoustic the influence to solidify protein;
B, the wet dregs of a decoction of terramycin utilize its pH of hydrochloric acid adjusting to be 0.5-1.0 after being cooled to normal temperature, and the dregs of a decoction that will wet stir;
C, the wet dregs of a decoction that will stir are put into the container of normal pressure, ultrasound environments, and under the stable cavitation condition, the control sound intensity is (0.5-10) W/cm
2, supersonic frequency is 20kHz-200kHz; Carry out the ultrasonic wave radiation, utilize hyperacoustic sound cavitation effect to make terramycin composition degraded in the wet dregs of a decoction, lost efficacy, filter then, add basifier the pH value of gained filter residue is adjusted to 4-5, dry or air dry gets final product.
2. the method for utilizing ultrasonic wave to eliminate left drug composition in the terramycin dregs of a decoction according to claim 1; It is characterized in that: in the steps A; The wet dregs of a decoction of terramycin are heated to 70 ℃-75 ℃ and be incubated 5min-15min, make it not receive hyperacoustic the influence to solidify protein.
3. the method for utilizing ultrasonic wave to eliminate left drug composition in the terramycin dregs of a decoction according to claim 1; It is characterized in that: among the step B; After the wet dregs of a decoction of terramycin were cooled to normal temperature, by the ratio of the hydrochloric acid 10mL-25mL of the wet dregs of a decoction adding of per 50 gram terramycin 0.4mol/L-0.6mol/L, regulating its pH was 0.5-1.0; The dregs of a decoction obtain dilution simultaneously, and the dregs of a decoction that will wet at last stir.
4. the method for utilizing ultrasonic wave to eliminate left drug composition in the terramycin dregs of a decoction according to claim 1, it is characterized in that: among the step C, the duration of ultrasonic wave radiation is 10min-30min.
5. the method for utilizing ultrasonic wave to eliminate left drug composition in the terramycin dregs of a decoction according to claim 1 is characterized in that: among the step C, filter gained filtrating and return step B, substitute part hydrochloric acid as the recycle of pH conditioning agent, realize the refuse zero-emission.
6. the method for utilizing ultrasonic wave to eliminate left drug composition in the terramycin dregs of a decoction according to claim 1 is characterized in that: among the step C, utilize calcium hydroxide or calcium oxide that the pH value of the gained dregs of a decoction is adjusted to 4-5.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104351483A (en) * | 2014-11-13 | 2015-02-18 | 河北圣雪大成制药有限责任公司 | Preparation method of completely fermented oxytetracycline calcium granules |
| CN105127178A (en) * | 2015-09-01 | 2015-12-09 | 宁夏大学 | Method for eliminating residual tetracycline in pharmaceutical dregs in physical-chemical oxidation combination manner |
| CN106422152A (en) * | 2016-09-22 | 2017-02-22 | 上海化工研究院 | Method for removing oxytetracycline in biological medicine waste residues |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0655153A (en) * | 1992-08-03 | 1994-03-01 | Canon Inc | Soil restoring method |
| CN1613534A (en) * | 2003-11-03 | 2005-05-11 | 浙江工业大学 | Processing method for antibiotics bacterial slag containing zinc |
| JP2006182579A (en) * | 2004-12-27 | 2006-07-13 | Ichimura:Kk | Manufacturing method of compost |
| CN101176511A (en) * | 2007-12-13 | 2008-05-14 | 河北大学 | Method for removing or reducing residual medicament component in ursocycline medicine slag |
| CN101380509A (en) * | 2008-10-16 | 2009-03-11 | 河南工业大学 | Macrolide antibiotic bacterium dregs innocent treatment method |
| CN102126813A (en) * | 2011-01-25 | 2011-07-20 | 山东美泉环保科技有限公司 | System and process for treating oxytetracycline waste water by anaerobic bio-treatment method |
| CN102285703A (en) * | 2011-06-15 | 2011-12-21 | 南京信息工程大学 | Method for ultrasonic removal of sulfadiazine in water |
-
2012
- 2012-01-19 CN CN201210017665.4A patent/CN102553891B/en not_active Expired - Fee Related
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0655153A (en) * | 1992-08-03 | 1994-03-01 | Canon Inc | Soil restoring method |
| CN1613534A (en) * | 2003-11-03 | 2005-05-11 | 浙江工业大学 | Processing method for antibiotics bacterial slag containing zinc |
| JP2006182579A (en) * | 2004-12-27 | 2006-07-13 | Ichimura:Kk | Manufacturing method of compost |
| CN101176511A (en) * | 2007-12-13 | 2008-05-14 | 河北大学 | Method for removing or reducing residual medicament component in ursocycline medicine slag |
| CN101380509A (en) * | 2008-10-16 | 2009-03-11 | 河南工业大学 | Macrolide antibiotic bacterium dregs innocent treatment method |
| CN102126813A (en) * | 2011-01-25 | 2011-07-20 | 山东美泉环保科技有限公司 | System and process for treating oxytetracycline waste water by anaerobic bio-treatment method |
| CN102285703A (en) * | 2011-06-15 | 2011-12-21 | 南京信息工程大学 | Method for ultrasonic removal of sulfadiazine in water |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104351483A (en) * | 2014-11-13 | 2015-02-18 | 河北圣雪大成制药有限责任公司 | Preparation method of completely fermented oxytetracycline calcium granules |
| CN105127178A (en) * | 2015-09-01 | 2015-12-09 | 宁夏大学 | Method for eliminating residual tetracycline in pharmaceutical dregs in physical-chemical oxidation combination manner |
| CN106422152A (en) * | 2016-09-22 | 2017-02-22 | 上海化工研究院 | Method for removing oxytetracycline in biological medicine waste residues |
| CN106422152B (en) * | 2016-09-22 | 2020-07-03 | 上海化工研究院有限公司 | Method for removing oxytetracycline in biological medicine waste residues |
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