CN102553084A - Phototherapy device - Google Patents
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- CN102553084A CN102553084A CN201210053425XA CN201210053425A CN102553084A CN 102553084 A CN102553084 A CN 102553084A CN 201210053425X A CN201210053425X A CN 201210053425XA CN 201210053425 A CN201210053425 A CN 201210053425A CN 102553084 A CN102553084 A CN 102553084A
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Abstract
The embodiment of the invention discloses a phototherapy device. The phototherapy device comprises a light source, a light guide system, a control system and a lighting refraction system, wherein the light source is used for conducting light with fixed wavelength to the light guide system, namely receiving light with fixed wavelength and from a light-filtering device and conducting the light with fixed wavelength to the light guide system; the light guide system is used for entering the body of a patient to be treated under the control of the control system and conducting the light with fixed wavelength and guided by the light source to the lighting refraction system; the control system is used for controlling the light guide system to enter the body of the patient to be treated, so that the lighting refraction system positioned at the front end of the light guide system reaches the focus in the body of the patient; and the lighting refraction system is used for irradiating the light with fixed wavelength and conducted by the light guide system on the focus in the body of the patient. The tubular continuous phototherapy device applied in the cavity is provided with tubular light-emitting diode (LED) encapsulation based on the cavity organs and optical path design and can provide uniform intracavity irradiation.
Description
Technical field
The present invention relates to medical instruments field, relate in particular to a kind of Phototherapeutic device.
Background technology
PDT (Photodynamic Therapy; PDT) former title photoradiation therapy (Photoradiation Therapy; PRT), (Photochemical Therapy, PCT), it is to utilize light to carry out a kind of new technique of medical diagnosis on disease and treatment to photochemotherapy.PDT application clinically can be divided into photodynamic diagnosis (being called fluorescence diagnosis again) and light treatment.Clinically, PDT only refers to the light treatment usually, and light power diagnosis is called fluorescence diagnosis.The light treatment is spectrum irradiation human body surface or the housing surface that utilizes specific band, can kill the sick cell tissue effectively through the photo-thermal complex effect, and mucosal tissue is solidified, and blood vessel solidifies obturation, reaches the healing purpose.
PDT is under the synergism of the light of specific wavelength and photosensitizer, to make the oxygen molecule in the cell produce free radical and single oxygen atom, causes cytotoxicity, reaches the effect of treatment disease.At present, PDT has been successfully applied to treatment dermatosis and tumor, like actinic keratosis, basal cell carcinoma, Bowen's disease etc.And the application that is widely known by the people most is exactly to be used to treat acne, and the blue light illumination propionibacterium acnes can make its endogenic porphyrin generation photochemical reaction, produces singlet oxygen, thereby kill bacteria reaches the effect of treatment acne.Increasing research proves a lot of antibacterials such as Gram-positive golden staphylococci; Gram negative porphyrin zygosaccharomyces, general Bordetella, haemophilus etc.; Through being killed after the irradiation of specific wavelength; Light like 405nm can be killed helicobacter pylori, and the light of 617nm can be killed haemophilus parainfluenzae, and the light of 664nm can be killed golden staphylococci etc.
PDT in medically application more and more widely, up to the present existing a plurality of hospitals adopt PDT aspects such as tumor, infectious disease are diagnosed and to be treated clinically.As in (like dermatosis) aspect the infectious disease treatment, the diagnosis and treatment of PDT have obtained good effect.Compared to the traditional treatment mode, the advantage of PDT is can stay cicatrix hardly, and big for area, and quantity is many, or the focus of obscure boundary Chu implements relatively easily, also is another selection when can't or be unwilling to accept traditional treatment.Side effect is also slighter usually.The HONGGUANG of high-purity, high power density, blue light and gold-tinted can also change cellularity, killing bacteria.
Also have in the recent period research to show that multiple pathogen in the human body (being outstanding with helicobacter pylori wherein) can be killed by visible light, the best light wave of sterilization effect is good reddish blue light.The mechanism of killing of helicobacter pylori is based on can produce a kind of endogenous photosensitizers " porphyrin " in its body, this material has very strong absworption peak to the light wave in 405+/-25 nanometer range, in about 505,550,570 and 655 nanometers less absworption peak is arranged.Chemical de excitation reaction takes place in " porphyrin " that absorb behind the light wave, can generate a large amount of active oxygens, singlet oxygen most importantly wherein, active oxygen can with multiple interaction of biomacromolecules, damaging cells structure or influence cell function, thereby generation killing action.
Visible light can transmit enough energy in these narrow wave-length coverages, these energy can be killed most of antibacterials.And the effect that light wave is killed is remarkable, not only along the surface effectively, better curative effect is arranged also under the surface.The degree of depth that different light is penetrated into tissue is different and difference to some extent with wavelength, and wavelength is long more, penetrates dark more.The light wave of 400 nanometers can penetrate about 1mm, and the light wave of 650 nanometers can penetrate about 3mm or more than.Therefore, can select the light wave of different wave length can reach the treatment degree of depth of wanting according to required penetration depth.The specially good effect wavelength of killing helicobacter pylori is 400 nanometers.In addition, multicolored radiance can provide effectively and more deep therapeutic effect.General this therapeutic effect can be killed the antibacterial of 99%-99.9%, and host's autoimmune system also is enough to kill remaining antibacterial.
Being used for the light source that the photo-therapeutic instrument of optical dynamic therapy generally selects for use at present has fluorescent lamp, electric filament lamp, LED, laser and chemiluminescence source etc., generally is that the method for the similar endoscope illuminator of utilization is provided with 1～2 light source.But the shortcoming of this photo-therapeutic instrument is fairly obvious.Its major defect has as follows: 1, light source is single, shines inhomogeneous; 2, the light source irradiation angle has restriction, can not reach 360 ° of irradiations; 3, in order to reach certain exposure rate, it is a hot spot that irradiation area is concentrated, and is not suitable for large-scale treatment.For addressing the above problem, the photo-therapeutic instrument that has uses spherical in scope or oval-shaped air bag struts cavity broadening one's vision, but because the restriction range of exposures of light source still is a hot spot.It is that luminous general power increases, but can only be used for external by the synthetic luminous body of led array group that the optical dynamic therapy lamp is also arranged at present.So the problems referred to above do not obtain basic solution.
Summary of the invention
Embodiment of the invention technical problem to be solved is; A kind of tubular continuous light therapy equipment that is applied to intracavity is provided; This Phototherapeutic device is a kind of medical apparatus and instruments of novel full pipeline internal therapy or the adnexa of existing endoscopic assistance; This Phototherapeutic device has tubular LED encapsulation and the light path design based on the cavity organ, and uniform intra cavitary irradiation can be provided.
In order to solve the problems of the technologies described above, the embodiment of the invention provides a kind of Phototherapeutic device that is applied to intracavity, comprising: light source, control system, light-conducting system and illumination dioptric system;
Light source is used for having to the conduction of said light-conducting system the light of fixed wave length, comprises that reception is from filtering apparatus and have the light of fixed wave length and this light with fixed wave length is conducted in the said light-conducting system;
Light-conducting system is used under the control of said control system, getting in patient's body to be treated, and will conduct to said illumination dioptric system by said light source light that import, that have fixed wave length;
Control system is used to control said light-conducting system and gets in patient's body to be treated, and makes the illumination dioptric system that is positioned at said light-conducting system front end arrive the intravital affected area of patient;
The illumination dioptric system is used for the light with fixed wave length of said light-conducting system conduction is radiated at the intravital focus of patient uniformly.
Wherein, said Phototherapeutic device also comprises:
The spectral match system is used for selecting for use the spectrum of different wave length to match colors according to patient's focus, kills the bacterium of curing the disease of affected area as radiation source, and said spectrographic wave-length coverage comprises: 360nm to 420nm.
Wherein, said light source comprises: lighting module and treatment module;
The illumination light module, the endoscope that is used to said Phototherapeutic device front end provides illumination;
The treatment optical module is used in said light-conducting system conduction and has light fixed wave length, that be used to treat patient's internal lesions.
Wherein, said treatment optical module comprises:
Led light source is used to produce or receive from light this filtering apparatus, that have fixed wave length; Said light source adopts pipe property LED;
Photodetector is used to detect light output situation;
Control circuit is coupled to the power supply unit of said led light source, is used for adjusting the brightness of said led light source and the work of control regulation and control member according to the detection signal of said photodetector;
The modulation member is used under the control of said control circuit, regulates and patient's focus is carried out the duration of illumination and the interval duration between twice illumination at every turn;
Filter wheel is used to control type and the wavelength through the light of this filter wheel; The type of said light comprises ultraviolet light, infrared light, visible light;
Light intensity detector is used to detect the light intensity that sees through, passes to the patient from filter wheel, and confirms to be used for this patient's dosage based on this light intensity;
Spectroanalysis instrument is used to receive and analyze the light from patient's affected area reflection.
Wherein, said illumination light module comprises:
The first primary lights semiconductor light sources is used to send first primary lights;
The second primary lights semiconductor light sources is used to send second primary lights;
Collecting lens is positioned on the light path of first primary lights and second primary lights, is used to converge first primary lights and second primary lights;
Optical fiber, the one of which end is positioned at the collecting lens along, and the other end connects endoscope.
Wherein, said illumination dioptric system is led emitter surface with the light of light source through a branch of optical fiber, at the end of each optical fiber prism is set, and makes around light evenly diffuses to through prismatical effect, arrives luminal surface/deep tissue; Perhaps
End at optical fiber is provided with reflectance coating, and the light transmission of a part is gone out, and the light of another part evenly diffuses to arrival luminal surface/deep tissue; Perhaps
In emitter surface corresponding optical channel is set, light is evenly shed through said optical channel, arrive luminal surface/deep tissue.
Wherein, said Phototherapeutic device also comprises: sacculus;
Said balloon structure comprises: body, gastric balloon and/or esophagus air bag; Gastric balloon and/or esophagus air bag are communicated with body near an end of body, and body is used for to gastric balloon and/or esophagus balloon inflation/deflation, and extract esophagus liquid, gastric juice;
Gastric balloon and/or esophagus air bag are used for after it gets into patient's cavity with Phototherapeutic device, make the said relatively patient's cavity of said Phototherapeutic device fix and prevent that stomach, esophagus are hemorrhage.
Wherein, the length of said esophagus air bag is 8～12 centimetres.
Wherein, said Phototherapeutic device also comprises the accessory inlet, is used to supply in the mate-assist therapy equipment mouth entering from then on patient body.
Wherein, said Phototherapeutic device gets in patient's body through patient's oral cavity or nasal cavity.
The Phototherapeutic device that the embodiment of the invention provided can realize covering fully the light treatment of any infected zone; And the rayed of optical density such as intimate is provided; Solve the problem that hot spot type irradiation apparatus can't the large tracts of land uniform irradiation; The congested phenomenon of the position edema that effectively reduces inflammation simultaneously, microcirculation improvement promotes the tissue repair healing and solves the drug tolerant bacteria intracavity to infect the problem that can't effect a radical cure.The Phototherapeutic device drug treatment that the embodiment of the invention provided is short, and it is low to predict complication, has safety.And has the design of histocompatibility sacculus.
Description of drawings
In order to be illustrated more clearly in the embodiment of the invention or technical scheme of the prior art; To do to introduce simply to the accompanying drawing of required use in embodiment or the description of the Prior Art below; Obviously, the accompanying drawing in describing below only is some embodiments of the present invention, for those of ordinary skills; Under the prerequisite of not paying creative work, can also obtain other accompanying drawing according to these accompanying drawings.
Fig. 1 is the Phototherapeutic device first example structure sketch map provided by the invention;
Fig. 2 is the Phototherapeutic device second example structure sketch map provided by the invention;
Fig. 3 is provided with prism for optical fiber connector, makes light evenly diffuse to sketch map all around through prismatical effect;
Fig. 4 is provided with optical channel for emitter surface, the sketch map that light is evenly shed;
Fig. 5 is single led light path sketch map;
Fig. 6 is single led irradiation sketch map;
Fig. 7 is the irradiation sketch map of a plurality of LED;
Fig. 8 is the distribution schematic diagram of a plurality of LED of plane receiving plane;
Sketch map when Fig. 9 reaches reasonable uniformity coefficient for the illumination property of receiving plane;
Figure 10 is Phototherapeutic device the 3rd an example structure sketch map provided by the invention.
The specific embodiment
The Phototherapeutic device that the embodiment of the invention provided can realize covering fully the light treatment of any infected zone; And the rayed of optical density such as intimate is provided; Solve the problem that hot spot type irradiation apparatus can't the large tracts of land uniform irradiation; The congested phenomenon of the position edema that effectively reduces inflammation simultaneously, microcirculation improvement promotes the tissue repair healing and solves the drug tolerant bacteria intracavity to infect the problem that can't effect a radical cure.The Phototherapeutic device drug treatment that the embodiment of the invention provided is short, and it is low to predict complication, has safety.And has the design of histocompatibility sacculus.
Phototherapeutic device provided by the invention mainly comprises following components: 1, spectral match system; 2, can send the light source of specific wavelength (for example 420nm, 850nm and 940nm); 3, light-conducting system; 4, intracavity illumination dioptric system; 5, mate-assist therapy system.Device provided by the invention both can be used as independently therapy equipment, also can cooperate with conventional endoscope, or use as the accessory of conventional endoscope, and its principle is consistent.For describing conveniently, the situation that various embodiments of the present invention cooperate with conventional endoscope with this Phototherapeutic device is that example describes.
To combine the accompanying drawing in the embodiment of the invention below, the technical scheme in the embodiment of the invention is carried out clear, intactly description, obviously, described embodiment only is the present invention's part embodiment, rather than whole embodiment.Based on the embodiment among the present invention, those of ordinary skills are not making the every other embodiment that is obtained under the creative work prerequisite, all belong to the scope of the present invention's protection.
Referring to Fig. 1, be the Phototherapeutic device first example structure sketch map provided by the invention, as shown in the figure, this device includes but not limited to: light source 1, control system 2, light-conducting system 3 and illumination dioptric system 4.
Light-conducting system 3 is used under the control of said control system, getting in patient's body to be treated, and will conduct to said illumination dioptric system 4 by said light source 1 light that import, that have fixed wave length.
Illumination dioptric system 4 is used for the light with fixed wave length of said light-conducting system 3 conduction is radiated at the intravital focus of patient uniformly.
The Phototherapeutic device that the embodiment of the invention provided can realize covering fully the light treatment of any infected zone; And the rayed of optical density such as intimate is provided; Solve the problem that hot spot type irradiation apparatus can't the large tracts of land uniform irradiation; The congested phenomenon of the position edema that effectively reduces inflammation simultaneously, microcirculation improvement promotes the tissue repair healing and solves the drug tolerant bacteria intracavity to infect the problem that can't effect a radical cure.The Phototherapeutic device drug treatment that the embodiment of the invention provided is short, and it is low to predict complication, has safety.
Referring to Fig. 2, be the Phototherapeutic device second example structure sketch map provided by the invention.In the present embodiment, with the structure and and the functions of components of more detailed this Phototherapeutic device of description.As shown in the figure, this Phototherapeutic device comprises: spectral match system 5, light source 1, light-conducting system 3, control system 2, illumination dioptric system 4.
Further, said treatment optical module comprises: led light source, photodetector, control circuit, modulation member, filter wheel, light intensity detector and spectroanalysis instrument.
Led light source is used to produce or receive from light this filtering apparatus, that have fixed wave length; Said light source adopts pipe property LED, is the light emitting diode semi-conductor solid-state light source, between this exiting surface surface, does not have the gap.The silica gel of the surperficial wrapping biological tolerability of led light source, the silica gel of bio-compatible property possesses biology performance, can be because of directly not combining to reduce its usefulness and service life with biosystem.Bio-compatible property silicone rubber has excellent biological compatibility, and is few to the irritated reaction of tissue nonirritant, avirulence, nothing, body rejection; Having good physicochemical property, with body fluid and organize and can keep its original elasticity and pliability in the contact process, be not degraded, is a kind of inert substance of quite stable.The led light source of wrapping biological tolerability silica gel can be high temperature resistant, can sterilize, and machine-shaping is convenient, is prone to processing engraving shape, and is easy to use.
Led light source is made up of a plurality of independently LED; Through the part series connection, the mode of whole parallel connection can reach the required brightness of treatment; Can implement personalized treatment again, the different exposure rates of different parts promptly are set according to the concrete condition in patient affected part through programme-control.The enforcement of this function also depends on the body soft durometer, the cooperation of the scale of length and tube outer surface.The moderate material body of this design Selection soft durometer makes its misery that can get into pipeline crooked in patient's body smoothly and reduce the patient, and fully conduction operation person's strength takes operation to the position again.The length of body will also can be designed to the body of different thicknesses according to treating required exposure rate according to the standard design of human body, and thin person can consider that the mode that per nasal gets into is designed to respective length, but slightly person's per os gets into.
Photodetector is used to detect light output situation.More concrete, photodetector is coupled in this light conductive liquid container and is used to detect light output situation in this light conductive liquid.
Control circuit; Be coupled to this led light source power supply unit; Can adjust this led light source brightness according to the detection signal of this photodetector; Control simultaneously should the regulation and control member, and then provides illumination is used for patient's phase I and illumination is not used for patient's second stage, and make illumination in the phase I be pulsed light according to or feasiblely should the phase I be longer than this second stage all the time in time.This control circuit can be connected to be used for storage data storehouse and user can input command and the outer computer of data; Therefrom receive data, these data and said phase I, second stage and be used for patient's the frequency or the pulse of phase I internal modulation in illumination relevant.
The modulation member is used under the control of said control circuit, regulates and patient's focus is carried out the duration of illumination and the interval duration between twice illumination at every turn.The modulation member comprises pulse-width modulation circuit, the first copped wave part and the second copped wave part; Shine in order to light modulated; With the treatment circulation that provides one or more circulations to form, each circulation of wherein said a plurality of circulation all comprises a second stage, and followed by phase I of second stage.In the phase I, illumination is used for the patient, in second stage, illumination is not used for the patient.This modulation member also is used to make the illumination pulsation of in each phase I, using, and shines so that pulsed light to be provided to the patient.
Filter wheel is used to control type and the wavelength through the light of this filter wheel; The type of said light comprises ultraviolet light, infrared light, visible light.More concrete; Filter wheel comprises first filter wheel and second filter wheel, first filter wheel have at least one in order to ultraviolet transmissive light modulation filter element, filter element, one in order to transmitted infrared light in order to the filter element of visible light transmissive and one in order to stop Resistance from any light transmission of this light source.Second filter wheel has a plurality of in order to select the filter element through the specific wavelength bandwidth of this second filter wheel.Further, first filter wheel and second filter wheel comprise driving device, in order to rotating filtering wheel, so that selected filter element aligns with light source, and then the light of required wavelength are provided.Preferably, said second filter wheel comprises leaning device, in order to the inclination filter wheel, so that the bandwidth that is provided by each filter element of this second filter wheel squints.
Light intensity detector is used to detect the light intensity that sees through, passes to the patient from filter wheel, and confirms to be used for this patient's dosage based on photoconduction and patient's during this light intensity and patient's the treatment distance.
Spectroanalysis instrument is used for receiving and analyzing from the light of patient's affected area reflection through fibre-optic waveguide.
Said illumination light module comprises that the first primary lights semiconductor light sources is used to send first primary lights.The second primary lights semiconductor light sources is used to send second primary lights.Collecting lens is positioned on the light path of first primary lights and second primary lights, is used to converge first primary lights and second primary lights.Optical fiber, the one of which end is positioned at the collecting lens along, and the other end connects endoscope.
Thereby adopt semiconductor laser as light source can energy efficient, the diameter that reduces to pass light path alleviate patient misery, eliminate the unnecessary heating of illumination intraluminal tissue, reduce lighting source volume, exempt repair and replacement to light source; The illumination light module adopts control device that primary light source is carried out switch and power adjustments, can realize color lighting, conveniently focus is observed.Transmit with fibre bundle with the illumination of the ordinary light source of spontaneous radiation in the existing endoscope and to compare; Illumination light module brightness provided by the invention is high, heat is little; Make endoscope's rich color true to nature; And can adjust the laser output power of each laser instrument according to the demand of observing focus, obtain suitable brightness, color and colourity.
Light-conducting system 3 is used under the control of said control system, getting in patient's body to be treated, and will conduct to said illumination dioptric system 4 by said light source 1 light that import, that have fixed wave length.The main body of this light-conducting system 3 is an optical fiber, it has side-scattered light intensity uniform distribution, illumination zone is wide, energy loss is little, with low cost, have plasticity, can carry out evenly characteristics such as illumination of certain bending, intracavity.Lateral emitting optical fiber is claimed entirely lighting optical fiber, linear optical fiber, leakage type optical fiber, heavy caliber light pipe again even also is called as rainbow optical fiber etc.It can not only transfer to the other end from optical fiber one end face with light, and can also light leaked out from its cladding surface, makes optical fiber integrally luminous.
Leaded light is carried out in the light-conducting system 3 main use special handlings evenly optical fiber of light leak.In the optical fiber of this light-conducting system 3, scattering object with different density and depth profile in sandwich layer and covering sandwich layer at the interface.When light conducting was transmitted in optical fiber, the part light conducting will be scattered body and scatter to outside the optical fiber equably from the side of optical fiber.The uniformity of optical fiber side scattered light intensity is to realize through the attenuation quotient that changes optical fiber diverse location place, and the change of attenuation quotient is to realize through the density and the degree of depth that changes optical fiber diverse location place scattering object.
Illumination dioptric system 4 is used for the light with fixed wave length of said light-conducting system 3 conduction is radiated at the intravital focus of patient uniformly.More concrete, said illumination dioptric system is led emitter surface with the light of light source through a branch of optical fiber, at the end of each optical fiber prism is set, and makes around light evenly diffuses to through prismatical effect, arrives luminal surface/deep tissue (as shown in Figure 3); Perhaps the end at optical fiber is provided with reflectance coating, and the light transmission of a part is gone out, and the light of another part evenly diffuses to arrival luminal surface/deep tissue; Perhaps corresponding optical channel is set, light is evenly shed through said optical channel, arrive luminal surface/deep tissue (as shown in Figure 4) in emitter surface.
Further, make the illumination dioptric system 4 can be with the light multiple implementation that evenly shed, present embodiment be listed wherein three kinds:
First kind is to utilize light intensity to equate, as shown in Figure 5.Single led distribution curve flux is I=I
0Cos θ, do following hypothesis: 1, the light intensity of corresponding point A only receives the influence of this LED and two adjacent LEDs directly over each LED; 2, the light intensity of the central point B of two LED top only receives the influence of these two LED.
If the light intensity that A, B among Fig. 5 are 2 equates, then be similar to and think even in the light intensity of AB line direction; With the vertical direction of AB line on identical conclusion is arranged; If the LED of both direction is in staggered distribution and when all reaching requiring that the point-to-point transmission light intensity equates, then think even in the light intensity of whole shadow surface.
Second kind is to utilize illumination to equate, as shown in Figure 5.Single led distribution curve flux I=I
0Cos θ, do following hypothesis: 1, the illumination of corresponding point A only receives the influence of this LED and two adjacent LEDs directly over each LED; 2, the illumination of the central point B of two LED top only receives the influence of these two LED;
If the illumination that A, B among Fig. 5 figure are 2 equates, then be similar to and think even in the illumination of AB line direction; With the vertical direction of AB line on identical conclusion is arranged; If the LED of both direction is in staggered distribution and when all reaching requiring that point-to-point transmission illumination equates, then think even in the light intensity of whole shadow surface.
The third is direct modeling.Fig. 6 is single led simulation sketch map; Fig. 7 is the simulation sketch map of a plurality of LED; Can know that by figure when LED quantity increased, the energy that the shadow surface mid portion receives was more even under the irradiation of each LED; Suitably the spacing between the adjustment LED can make the Energy distribution of shadow surface reach a degree the most uniformly.Fig. 8 is the distribution simulation sketch map of a plurality of LED of plane receiving plane, and is as shown in the figure, and the horizontal range of two LED of same row is d, is h with the vertical distance of two adjacent LED of string.Through the value of continuous adjustment d and h, and the emulation through simulation softward, can draw a suitable d and h value, make the illuminance uniformity of receiving plane reach reasonable degree, as shown in Figure 9.
The Phototherapeutic device that the embodiment of the invention provided can realize covering fully the light treatment of any infected zone; And the rayed of optical density such as intimate is provided; Solve the problem that hot spot type irradiation apparatus can't the large tracts of land uniform irradiation; The congested phenomenon of the position edema that effectively reduces inflammation simultaneously, microcirculation improvement promotes the tissue repair healing and solves the drug tolerant bacteria intracavity to infect the problem that can't effect a radical cure.The Phototherapeutic device drug treatment that the embodiment of the invention provided is short, and it is low to predict complication, has safety.
Referring to Figure 10, be Phototherapeutic device the 3rd example structure sketch map provided by the invention.The Phototherapeutic device that present embodiment provides; Comprise that also structure and the function of light source 1, light-conducting system 3, control system 2, illumination dioptric system 4, spectral match system 5 and above-mentioned parts and the Phototherapeutic device that a last embodiment provides are basic identical, repeat no more in the present embodiment.The difference of the Phototherapeutic device that a Phototherapeutic device that this present embodiment provides and a last embodiment provide is; Increase some new accessory or auxiliary device; Shown in figure 11; The Phototherapeutic device that present embodiment provides also comprises: sacculus except that light source 1, light-conducting system 3, control system 2, illumination dioptric system 4, spectral match system 5;
Said balloon structure comprises: body 6, gastric balloon 7 and/or esophagus air bag 8; Gastric balloon 7 and/or esophagus air bag 8 are communicated with body 6 near an end of body, and body 6 is used for to gastric balloon 7 and/or esophagus air bag 8 inflation/deflations, and extract esophagus liquid, gastric juice.Gastric balloon 7 and/or esophagus air bag 8 are used for after it gets into patient's cavity with Phototherapeutic device, make the said relatively patient's cavity of said Phototherapeutic device fix and prevent that stomach, esophagus are hemorrhage.
More concrete; In body 6, also have esophagus liquid extracting cavity; End attaching in esophagus liquid extracting cavity accordingly has esophagus liquid extraction tube, has esophagus liquid extraction aperture with esophagus air bag 8 contiguous body sides, and esophagus liquid extraction aperture, esophagus liquid extracting cavity, esophagus liquid extraction tube communicate.Be connected stomach buffer air bag and esophagus buffer air bag respectively in the centre of stomach gas tube and the centre of esophagus gas tube, it be the rubber-like cystidium.The esophagus liquid extracting cavity that increases can be avoided causing secondary infection in the secretions suction lung; But the inflation situation of buffer air bag direct observation stomach, esophagus air bag and adjustment in time; Also be convenient to the changing-over syringe; The length of esophagus air bag is 8～12 centimetres, can reduce behind the esophagus airbag aeration compressing to left bronchus and left atrium, the utensil that also uses when preventing hemorrhage emergent of stomach, esophagus.
Further, said Phototherapeutic device also comprises accessory inlet 9, is used to supply in the mate-assist therapy equipment mouth entering from then on patient body.Can include but not limited to through accessory 9 devices that are used with Phototherapeutic device provided by the invention that enter the mouth: insertion system, administration injection apparatus.
Insertion system: insertion system possesses installs first sacculus on the insertion section of endoscope; And guide said insertion section to insert in the body cavity; And possess the insertion assistive device of second sacculus and on the balloon control apparatus of the supply of first sacculus and second sacculus being carried out air, attraction, link the end connector that pipeline is arranged at its leading section.First pipeline that insertion system will be communicated with first sacculus on being installed in endoscope insertion part, be installed in second pipeline that inserts second sacculus on the assistive device and is communicated with, the 3rd pipeline of supply of lubricant is attached on the balloon control apparatus between insertion section and insertion assistive device; Perhaps; With said three pipelines be connected to and external device (ED) between endoscope connector portion and be attached on the balloon control apparatus; Therefore can easily carry out and balloon control apparatus between bridging work, can eliminate the binding mistake simultaneously.The insertion section and insertion assistive device of insertion system through alternately inserting endoscope inserted and observed to digestive tube such as the deep of small intestinal or large intestine etc.
The administration injection apparatus: an end of its tube for transfusion is positioned at the bottom of reservoir, and the other end is equipped with the medicine shower nozzle, and the front end of said medicine shower nozzle has spherical, on spherical, is provided with several spray orifices.On the bottle cap of reservoir, be plugged with gas tube, an end of gas tube is positioned at the top of reservoir liquid level, and the other end is connected with the extruding gas cell.When anaesthetizing before the cervix uteri intrauterine surgical to stomach or women; The medicine shower nozzle that will have spherical inserts in stomach or the cervix uteri uterine cavity, through the air in the extruding gas cell extruding reservoir, the anesthesia medicinal liquid is ejected on stomach or the cervix uteri uterine cavity through the spray orifice on the medicine shower nozzle uniformly then; Reduced patient's misery; Its practicality rational in infrastructure need not particular surgical instrument, and is easy and simple to handle.
Further, Phototherapeutic device provided by the invention is provided with aseptic separation sleeve in endoscope.Aseptic separation sleeve is included in the outer surface of endoscope; Adopt rigid plastics or lucite or glass to process; The observation port position of corresponding endoscope is the transparent body on the separation sleeve, is shaped on the convex-concave circle stricture of vagina of similar optical glass on it, and the part that separation sleeve inserts human body all is transparent bodies; The fiber bench position of corresponding cavity mirror is provided with card inserting mouth on the separation sleeve, is coated with antifoggant at the transparent body position of separation sleeve inwall.
The Phototherapeutic device that the embodiment of the invention provided can realize covering fully the light treatment of any infected zone; And the rayed of optical density such as intimate is provided; Solve the problem that hot spot type irradiation apparatus can't the large tracts of land uniform irradiation; The congested phenomenon of the position edema that effectively reduces inflammation simultaneously, microcirculation improvement promotes the tissue repair healing and solves the drug tolerant bacteria intracavity to infect the problem that can't effect a radical cure.The Phototherapeutic device drug treatment that the embodiment of the invention provided is short, and it is low to predict complication, has safety.
One of ordinary skill in the art will appreciate that all or part of flow process that realizes in the foregoing description method; Be to instruct relevant hardware to accomplish through computer program; Described program can be stored in the computer read/write memory medium; This program can comprise the flow process like the embodiment of above-mentioned each side method when carrying out.Wherein, described storage medium can be magnetic disc, CD, read-only storage memory body (Read-Only Memory, ROM) or at random store memory body (Random Access Memory, RAM) etc.
Above disclosedly be merely a kind of preferred embodiment of the present invention, can not limit the present invention's interest field certainly with this, the equivalent variations of therefore doing according to claim of the present invention still belongs to the scope that the present invention is contained.
Claims (10)
1. a Phototherapeutic device is characterized in that, comprising: light source, control system, light-conducting system and illumination dioptric system;
Light source is used for having to the conduction of said light-conducting system the light of fixed wave length, comprises that reception is from filtering apparatus and have the light of fixed wave length and this light with fixed wave length is conducted in the said light-conducting system;
Light-conducting system is used under the control of said control system, getting in patient's body to be treated, and will conduct to said illumination dioptric system by said light source light that import, that have fixed wave length;
Control system is used to control said light-conducting system and gets in patient's body to be treated, and makes the illumination dioptric system that is positioned at said light-conducting system front end arrive the intravital affected area of patient;
The illumination dioptric system is used for the light with fixed wave length of said light-conducting system conduction is radiated at the intravital focus of patient uniformly.
2. Phototherapeutic device as claimed in claim 1 is characterized in that, said Phototherapeutic device also comprises:
The spectral match system is used for selecting for use the spectrum of different wave length to match colors according to patient's focus, kills the bacterium of curing the disease of affected area as radiation source, and said spectrographic wave-length coverage comprises: 360nm to 420nm.
3. Phototherapeutic device as claimed in claim 1 is characterized in that, said light source comprises: lighting module and treatment module;
The illumination light module, the endoscope that is used to said Phototherapeutic device front end provides illumination;
The treatment optical module is used in said light-conducting system conduction and has light fixed wave length, that be used to treat patient's internal lesions.
4. Phototherapeutic device as claimed in claim 3 is characterized in that, said treatment optical module comprises:
Led light source is used to produce or receive from light this filtering apparatus, that have fixed wave length; Said light source adopts pipe property LED;
Photodetector is used to detect light output situation;
Control circuit is coupled to the power supply unit of said led light source, is used for adjusting the brightness of said led light source and the work of control regulation and control member according to the detection signal of said photodetector;
The modulation member is used under the control of said control circuit, regulates and patient's focus is carried out the duration of illumination and the interval duration between twice illumination at every turn;
Filter wheel is used to control type and the wavelength through the light of this filter wheel; The type of said light comprises ultraviolet light, infrared light, visible light;
Light intensity detector is used to detect the light intensity that sees through, passes to the patient from filter wheel, and confirms to be used for this patient's dosage based on this light intensity;
Spectroanalysis instrument is used to receive and analyze the light from patient's affected area reflection.
5. Phototherapeutic device as claimed in claim 3 is characterized in that, said illumination light module comprises:
The first primary lights semiconductor light sources is used to send first primary lights;
The second primary lights semiconductor light sources is used to send second primary lights;
Collecting lens is positioned on the light path of first primary lights and second primary lights, is used to converge first primary lights and second primary lights;
Optical fiber, the one of which end is positioned at the collecting lens along, and the other end connects endoscope.
6. like each described Phototherapeutic device in the claim 1 to 5; It is characterized in that; Said illumination dioptric system is led emitter surface with the light of light source through a branch of optical fiber; End at each optical fiber is provided with prism, makes around light evenly diffuses to through prismatical effect, arrives luminal surface/deep tissue; Perhaps
End at optical fiber is provided with reflectance coating, and the light transmission of a part is gone out, and the light of another part evenly diffuses to arrival luminal surface/deep tissue; Perhaps
In emitter surface corresponding optical channel is set, light is evenly shed through said optical channel, arrive luminal surface/deep tissue.
7. Phototherapeutic device as claimed in claim 6 is characterized in that said Phototherapeutic device also comprises: sacculus;
Said balloon structure comprises: body, gastric balloon and/or esophagus air bag; Gastric balloon and/or esophagus air bag are communicated with body near an end of body, and body is used for to gastric balloon and/or esophagus balloon inflation/deflation, and extract esophagus liquid, gastric juice;
Gastric balloon and/or esophagus air bag are used for after it gets into patient's cavity with Phototherapeutic device, make the said relatively patient's cavity of said Phototherapeutic device fix and prevent that stomach, esophagus are hemorrhage.
8. Phototherapeutic device as claimed in claim 7 is characterized in that, the length of said esophagus air bag is 8～12 centimetres.
9. Phototherapeutic device as claimed in claim 6 is characterized in that, said Phototherapeutic device also comprises the accessory inlet, is used to supply in the mate-assist therapy equipment mouth entering from then on patient body.
10. like each described Phototherapeutic device in the claim 1 to 5, it is characterized in that said Phototherapeutic device gets in patient's body through patient's oral cavity or nasal cavity.
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| CN201210053425.XA CN102553084B (en) | 2012-03-02 | 2012-03-02 | Phototherapy device |
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| CN201210053425.XA CN102553084B (en) | 2012-03-02 | 2012-03-02 | Phototherapy device |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107224671A (en) * | 2017-06-09 | 2017-10-03 | 深圳市美的连医疗电子股份有限公司 | Cavity therapeutic equipment |
| CN107970525A (en) * | 2017-12-06 | 2018-05-01 | 刘承佳 | A kind of insertion type Neonatal jaundice phototherapy instrument |
| CN107982641A (en) * | 2017-12-06 | 2018-05-04 | 张艾丽 | A kind of light pipe for being exclusively used in neonate and intervening phototherapy |
| CN108635678A (en) * | 2018-08-02 | 2018-10-12 | 夏云程 | Light guide structure, light-emitting device, therapeutic equipment, beauty mask and integrated therapeutical system |
| CN109937071A (en) * | 2016-11-17 | 2019-06-25 | 一般财团法人生物动力学研究所 | Photoradiation treatment based on endoscope uses up irradiation probe |
| CN110353965A (en) * | 2013-11-11 | 2019-10-22 | 乔伊鲁克斯公司 | The household light emitting diode and massage apparatus restored for vagina |
| CN111388873A (en) * | 2020-03-26 | 2020-07-10 | 苏州科技城医院 | Gastric cavity phototherapy sterilization device and method based on blue light L ED |
| CN112402807A (en) * | 2020-11-18 | 2021-02-26 | 中国人民解放军总医院 | Photodynamic therapeutic apparatus for human body cavity and cavity organ |
| CN116139415A (en) * | 2023-02-20 | 2023-05-23 | 广东国志激光技术有限公司 | Phototherapy system and phototherapy capsule |
| US11833101B2 (en) | 2015-10-02 | 2023-12-05 | Joylux, Inc. | Light-emitting diode and massage device for delivering focused light for vaginal rejuvenation |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110353965A (en) * | 2013-11-11 | 2019-10-22 | 乔伊鲁克斯公司 | The household light emitting diode and massage apparatus restored for vagina |
| US11833101B2 (en) | 2015-10-02 | 2023-12-05 | Joylux, Inc. | Light-emitting diode and massage device for delivering focused light for vaginal rejuvenation |
| CN109937071A (en) * | 2016-11-17 | 2019-06-25 | 一般财团法人生物动力学研究所 | Photoradiation treatment based on endoscope uses up irradiation probe |
| CN107224671A (en) * | 2017-06-09 | 2017-10-03 | 深圳市美的连医疗电子股份有限公司 | Cavity therapeutic equipment |
| CN107970525A (en) * | 2017-12-06 | 2018-05-01 | 刘承佳 | A kind of insertion type Neonatal jaundice phototherapy instrument |
| CN107982641A (en) * | 2017-12-06 | 2018-05-04 | 张艾丽 | A kind of light pipe for being exclusively used in neonate and intervening phototherapy |
| CN108635678A (en) * | 2018-08-02 | 2018-10-12 | 夏云程 | Light guide structure, light-emitting device, therapeutic equipment, beauty mask and integrated therapeutical system |
| CN111388873A (en) * | 2020-03-26 | 2020-07-10 | 苏州科技城医院 | Gastric cavity phototherapy sterilization device and method based on blue light L ED |
| CN112402807A (en) * | 2020-11-18 | 2021-02-26 | 中国人民解放军总医院 | Photodynamic therapeutic apparatus for human body cavity and cavity organ |
| CN112402807B (en) * | 2020-11-18 | 2021-11-23 | 中国人民解放军总医院 | Photodynamic therapeutic apparatus for human body cavity and cavity organ |
| CN116139415A (en) * | 2023-02-20 | 2023-05-23 | 广东国志激光技术有限公司 | Phototherapy system and phototherapy capsule |
| CN116139415B (en) * | 2023-02-20 | 2024-01-26 | 广东国志激光技术有限公司 | Phototherapy system and phototherapy capsule |
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| CN102553084B (en) | 2014-12-10 |
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