CN102552104A - Gel for treating vaginitis and preparation method of gel - Google Patents
Gel for treating vaginitis and preparation method of gel Download PDFInfo
- Publication number
- CN102552104A CN102552104A CN2010106017722A CN201010601772A CN102552104A CN 102552104 A CN102552104 A CN 102552104A CN 2010106017722 A CN2010106017722 A CN 2010106017722A CN 201010601772 A CN201010601772 A CN 201010601772A CN 102552104 A CN102552104 A CN 102552104A
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- China
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- gel
- purified water
- glycerol
- hypromellose
- colpitic
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Abstract
The invention discloses a gel for treating vaginitis and a preparation method of the gel. The gel consists of povidone iodine, potassium iodate, glycerol, hydroxypropyl methylcellulose and purified water. According to the preparation method of the gel, the gel is finally obtained by process flows of swelling, stirring, dissolving and the like. According to the medicinal gel, the defects of traditional suppository and lotion, such as easiness for polluting clothes, and easiness for volatilization and scatter can be overcome and higher social benefits are obtained.
Description
Technical field
The present invention relates to biomedicine field, be specifically related to colpitic gel of a kind of treatment and preparation method thereof.
Background technology
Vaginitis is the inflammation of connective tissue under vaginal mucosa and the mucosa, is common gynecological disease.Common vaginitis has bacterial vaginitis, trichomonal vaginitis and colpitis mycotica etc.Mostly the colpitic common dosage forms of clinical treatment is suppository and solution, the easy pollution clothes of suppository, volatile, wandering shortcoming that lotion exists.
Gel is transparent semisolid, the quality uniform and smooth, and tack is strong, and release is fast, and the holdup time is long, is prone to eccysis, and pollution clothes not is to skin and the non-irritating characteristics of mucosa.The present invention aims to provide a kind of gel, to overcome the defective of above common dosage forms.
Summary of the invention
The object of the invention is to provide colpitic gel of a kind of treatment and preparation method thereof.
The colpitic gel of treatment of the present invention, form by the raw material of following weight portion:
Povidone iodine 20～70 potassium iodate 5～15 glycerol 50～150
Hypromellose 9～23 purified water 700～1300
The present invention preferably treats colpitic gel, is made up of the raw material of following weight portion: gather dimension
Ketone iodine 70 potassium iodate 15 glycerol 150
Hypromellose 23 purified water 1200
Another preferably treats colpitic gel the present invention, is made up of the raw material of following weight portion:
Povidone iodine 50 potassium iodate 10 glycerol 100
Hypromellose 18 purified water 822
Another preferably treats colpitic gel the present invention, is made up of the raw material of following weight portion:
Povidone iodine 30 potassium iodate 6 glycerol 70
Hypromellose 10 purified water 700
The method for preparing of the colpitic gel of treatment of the present invention comprises the steps:
1, with the purified water abundant swelling of hypromellose, is the homogeneous transparent gel, obtains substrate with 200～550 weight portions;
2, povidone iodine is dissolved in the purified water of 50～150 weight portions, is stirred to dissolving, add potassium iodate, be stirred to dissolving, obtain active ingredient solution;
3, above substrate is mixed with active ingredient solution, adds glycerol, fully stirs, and adds the purified water of residuals weight part, promptly gets.
The specific embodiment
Embodiment 1
Raw material:
Povidone iodine 70g potassium iodate 15g glycerol 150g
Hypromellose 23g purified water 1200g
Method for making:
1, with the purified water abundant swelling of hypromellose, is the homogeneous transparent gel, obtains substrate with the 550g weight portion;
2, povidone iodine is dissolved in the purified water of 150g weight portion, is stirred to dissolving, add potassium iodate, be stirred to dissolving, obtain active ingredient solution;
3, above substrate is mixed with active ingredient solution, adds glycerol, fully stirs, and adds the purified water of residuals weight part, makes drug gel 1458g.
Embodiment 2
Raw material:
Povidone iodine 50g potassium iodate 10g glycerol 100g
Hypromellose 18g purified water 822g
Method for making:
1, with the purified water abundant swelling of hypromellose, is the homogeneous transparent gel, obtains substrate with the 450g weight portion;
2, povidone iodine is dissolved in the purified water of 100g weight portion, is stirred to dissolving, add potassium iodate, be stirred to dissolving, obtain active ingredient solution;
3, above substrate is mixed with active ingredient solution, adds glycerol, fully stirs, and adds the purified water of residuals weight part, makes drug gel 1000g.
Embodiment 3
Raw material:
Povidone iodine 30g potassium iodate 6g glycerol 70g
Hypromellose 10g purified water 700g
Method for making:
1, with the purified water abundant swelling of hypromellose, is the homogeneous transparent gel, obtains substrate with the 200g weight portion;
2, povidone iodine is dissolved in the purified water of 50g weight portion, is stirred to dissolving, add potassium iodate, be stirred to dissolving, obtain active ingredient solution;
3, above substrate is mixed with active ingredient solution, adds glycerol, fully stirs, and adds the purified water of residuals weight part, makes drug gel 816g.
Claims (6)
1. treat colpitic gel for one kind, it is characterized in that forming by the component of following weight proportion:
Povidone iodine 20～70 potassium iodate 5～15 glycerol 50～150
Hypromellose 9～23 purified water 700～1300.
2. the colpitic gel of treatment as claimed in claim 1 is characterized in that being made up of the component of following weight proportion:
Povidone iodine 70 potassium iodate 15 glycerol 150
Hypromellose 23 purified water 1200.
3. the colpitic gel of treatment as claimed in claim 1 is characterized in that being made up of the component of following weight proportion:
Povidone iodine 50 potassium iodate 10 glycerol 100
Hypromellose 18 purified water 822.
4. the colpitic gel of treatment as claimed in claim 1 is characterized in that being made up of the component of following weight proportion:
Povidone iodine 30 potassium iodate 6 glycerol 70
Hypromellose 10 purified water 700.
5. like the colpitic gel of the described treatment of claim 1～4, it is characterized in that method for preparing may further comprise the steps:
(1), with the purified water abundant swelling of hypromellose with 200～550 weight portions, be the homogeneous transparent gel, obtain substrate;
(2), povidone iodine is dissolved in the purified water of 50～150 weight portions, be stirred to dissolving, add potassium iodate, be stirred to dissolving, obtain active ingredient solution;
(3), above substrate mixes with active ingredient solution, adds glycerol, fully stirs, and adds the purified water of residuals weight part, promptly get.
One kind the treatment colpitic gel method for preparing, it is characterized in that may further comprise the steps:
(1), with the purified water abundant swelling of hypromellose with 200～550 weight portions, be the homogeneous transparent gel, obtain substrate;
(2), povidone iodine is dissolved in the purified water of 50～150 weight portions, be stirred to dissolving, add potassium iodate, be stirred to dissolving, obtain active ingredient solution;
(3), above substrate mixes with active ingredient solution, adds glycerol, fully stirs, and adds the purified water of residuals weight part, promptly get.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010106017722A CN102552104A (en) | 2010-12-18 | 2010-12-18 | Gel for treating vaginitis and preparation method of gel |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010106017722A CN102552104A (en) | 2010-12-18 | 2010-12-18 | Gel for treating vaginitis and preparation method of gel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102552104A true CN102552104A (en) | 2012-07-11 |
Family
ID=46399577
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010106017722A Pending CN102552104A (en) | 2010-12-18 | 2010-12-18 | Gel for treating vaginitis and preparation method of gel |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102552104A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102885852A (en) * | 2012-10-23 | 2013-01-23 | 武汉迪奥药业有限公司 | Povidone iodine ointment and preparation method thereof |
| CN105878174A (en) * | 2016-04-26 | 2016-08-24 | 广州帝奇医药技术有限公司 | Solid dispersion and preparation method and application thereof |
| CN110151684A (en) * | 2019-07-01 | 2019-08-23 | 广州润虹医药科技股份有限公司 | A kind of antibacterial gynecological gel and its preparation method and application |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1730097A (en) * | 2005-07-25 | 2006-02-08 | 华中农业大学 | Pharmaceutical composition for preventing and curing endometritis and retained afterbirth disease of milk cow |
| CN101439044A (en) * | 2008-12-26 | 2009-05-27 | 华中农业大学 | Compound povidone iodine gel for treating mastitis of milk cattle as well as preparation method and application |
-
2010
- 2010-12-18 CN CN2010106017722A patent/CN102552104A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1730097A (en) * | 2005-07-25 | 2006-02-08 | 华中农业大学 | Pharmaceutical composition for preventing and curing endometritis and retained afterbirth disease of milk cow |
| CN101439044A (en) * | 2008-12-26 | 2009-05-27 | 华中农业大学 | Compound povidone iodine gel for treating mastitis of milk cattle as well as preparation method and application |
Non-Patent Citations (1)
| Title |
|---|
| 沈丽琳 等: "聚维酮碘凝胶的制备与质量控制", 《中国医院药学杂志》, vol. 27, no. 1, 31 January 2007 (2007-01-31), pages 111 - 112 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102885852A (en) * | 2012-10-23 | 2013-01-23 | 武汉迪奥药业有限公司 | Povidone iodine ointment and preparation method thereof |
| CN105878174A (en) * | 2016-04-26 | 2016-08-24 | 广州帝奇医药技术有限公司 | Solid dispersion and preparation method and application thereof |
| CN105878174B (en) * | 2016-04-26 | 2021-06-29 | 广州帝奇医药技术有限公司 | Solid dispersion and preparation method and application thereof |
| CN110151684A (en) * | 2019-07-01 | 2019-08-23 | 广州润虹医药科技股份有限公司 | A kind of antibacterial gynecological gel and its preparation method and application |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20120711 |