CN102526511A - Chinese medicinal composition for treating hypertension - Google Patents
Chinese medicinal composition for treating hypertension Download PDFInfo
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- CN102526511A CN102526511A CN2012100368160A CN201210036816A CN102526511A CN 102526511 A CN102526511 A CN 102526511A CN 2012100368160 A CN2012100368160 A CN 2012100368160A CN 201210036816 A CN201210036816 A CN 201210036816A CN 102526511 A CN102526511 A CN 102526511A
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- 206010020772 Hypertension Diseases 0.000 title claims abstract description 21
- 239000000203 mixture Substances 0.000 title claims abstract description 11
- 241000628997 Flos Species 0.000 claims description 15
- 239000003814 drug Substances 0.000 claims description 13
- 241000237903 Hirudo Species 0.000 claims description 9
- 230000001631 hypertensive effect Effects 0.000 claims description 7
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims description 7
- 241000219780 Pueraria Species 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 4
- 235000013399 edible fruits Nutrition 0.000 abstract 2
- 244000020518 Carthamus tinctorius Species 0.000 abstract 1
- 235000003255 Carthamus tinctorius Nutrition 0.000 abstract 1
- 244000035851 Chrysanthemum leucanthemum Species 0.000 abstract 1
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 abstract 1
- 244000192528 Chrysanthemum parthenium Species 0.000 abstract 1
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 abstract 1
- 241000196324 Embryophyta Species 0.000 abstract 1
- 241000305492 Gastrodia Species 0.000 abstract 1
- 241000545744 Hirudinea Species 0.000 abstract 1
- 244000083012 Ipomoea cairica Species 0.000 abstract 1
- 235000000802 Leonurus cardiaca ssp. villosus Nutrition 0.000 abstract 1
- 241000212322 Levisticum officinale Species 0.000 abstract 1
- 244000170916 Paeonia officinalis Species 0.000 abstract 1
- 235000006484 Paeonia officinalis Nutrition 0.000 abstract 1
- 244000046146 Pueraria lobata Species 0.000 abstract 1
- 235000010575 Pueraria lobata Nutrition 0.000 abstract 1
- 235000017276 Salvia Nutrition 0.000 abstract 1
- 240000007164 Salvia officinalis Species 0.000 abstract 1
- 240000006079 Schisandra chinensis Species 0.000 abstract 1
- 244000081822 Uncaria gambir Species 0.000 abstract 1
- 239000001645 levisticum officinale Substances 0.000 abstract 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 4
- 230000036772 blood pressure Effects 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 230000008030 elimination Effects 0.000 description 3
- 238000003379 elimination reaction Methods 0.000 description 3
- 230000003203 everyday effect Effects 0.000 description 3
- 210000004185 liver Anatomy 0.000 description 3
- 239000002893 slag Substances 0.000 description 3
- 208000007530 Essential hypertension Diseases 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 206010008111 Cerebral haemorrhage Diseases 0.000 description 1
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 241000305491 Gastrodia elata Species 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 201000004239 Secondary hypertension Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 230000036592 analgesia Effects 0.000 description 1
- 230000001773 anti-convulsant effect Effects 0.000 description 1
- 230000003276 anti-hypertensive effect Effects 0.000 description 1
- 210000000436 anus Anatomy 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 230000003727 cerebral blood flow Effects 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 239000003218 coronary vasodilator agent Substances 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 201000001421 hyperglycemia Diseases 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 208000031225 myocardial ischemia Diseases 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 230000008736 traumatic injury Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a Chinese medicinal composition for treating hypertension, and is characterized in that: the Chinese medicinal composition is prepared from the following components in part by weight: 6 to 10 parts of leech, 2 to 4 parts of tall gastrodia tuber, 10 to 20 parts of sea-ear shell, 8 to 10 parts of gambir plant, 9 to 10 parts of wild chrysanthemum, 3 to 5 parts of cairo morning glory, 5 to 10 parts of root of red-rooted salvia, 1 to 2 parts of motherwort fruit, 7 to 10 parts of Chinese magnoliavine fruit, 2 to 4 parts of raw white paeony root, 5 to 10 parts of kudzuvine root, 3 to 6 parts of Szechuan lovage rhizome and 2 to 4 parts of safflower. The Chinese medicinal composition has an obvious curative effect of treating hypertension and complication caused by the hypertension.
Description
Technical field the present invention relates to a kind of pharmaceutical composition, relates to the hypertensive Chinese medicine composition of a kind of treatment more specifically.
Background technology
Hypertension (Hypertension) is a kind of global common disease, and the prevalence of countries in the world is up to 10%-20%, and can cause the pathological changes of cerebrovascular, heart, kidney, and agnogenic hyperpietic claims essential hypertension or secondary hypertension.In China, the main directly complication of hypertension is a cerebrovascular, especially cerebral hemorrhage.The primary hypertension patient that one group of 312 example is in hospital was followed up a case by regular visits to through 15 years-18 years for a long time, because the heart, brain, dead 97 examples of kidney complication account for 74.6% of whole causes of the death.In 596 routine senile hypertensions follow-up observation in perspective 27 months research, the heart, cerebrovascular accumulation incidence rate are 68.79%, and cerebrovascular accumulation incidence rate is 36.91%.Research shows that blood pressure is high more, and the incidence rate of complication is also high more.
At present, if the drug main Western medicine of treatment hypertension.Because doctor trained in Western medicine can only be controlled, can not thoroughly cure hypertension, hyperlipidemia, hyperglycemia, therefore must take medicine all the life, not only increased the weight of patient's burden greatly but also taken for a long time also and can have side effects.
Summary of the invention
The present invention is the deficiency that overcomes above-mentioned prior art, provides a kind of treatment hypertensive Chinese medicine composition, selects Chinese herbal medicine for use, and it is obvious to have an antihypertensive effect, the characteristics that side effect is little.
The present invention adopts following technical scheme to realize:
The hypertensive Chinese medicine composition of a kind of treatment is characterized in that, is to be processed by the component of following parts by weight: Hirudo 6-10 part, Rhizoma Gastrodiae 2-4 part; Concha Haliotidis 10-20 part, Ramulus Uncariae Cum Uncis 8-10 part, Flos Chrysanthemi Indici 9-10 part, Radix seu Herba Tetrastigmatis Hypoglauci 3-5 part; Radix Salviae Miltiorrhizae 5-10 part, Fructus Leonuri 1-2 part, Fructus Schisandrae Chinensis 7-10 part, Radix Paeoniae Alba 2-4 part; Radix Puerariae 5-10 part, Rhizoma Chuanxiong 3-6 part, Flos Carthami 2-4 part.
Further, the hypertensive Chinese medicine composition of a kind of treatment, it is characterized in that: the parts by weight of each component are following: 8 parts of Hirudos, 3 parts in Rhizoma Gastrodiae; 15 parts of Concha Haliotidis, 9 parts of Ramulus Uncariae Cum Unciss, 9 parts of Flos Chrysanthemi Indicis, 4 parts of Radix seu Herba Tetrastigmatis Hypoglaucis; 7 parts of Radix Salviae Miltiorrhizaes, 1 part of Fructus Leonuri, 8 parts of Fructus Schisandrae Chinensis, 3 parts of Radix Paeoniae Alba; 6 parts of Radix Puerariaes, 4 parts of Rhizoma Chuanxiongs, 3 parts on Flos Carthami.
In each component wherein of the present invention:
Hirudo, the popular name Hirudo is the traditional extraordinary medicinal aquatic animal of China, its dry products is concocted the back traditional Chinese medical science and is used as medicine, and has effects such as treatment apoplexy, hypertension, the clear stasis of blood, traumatic injury.
Rhizoma Gastrodiae, Rhizoma Gastrodiae have calmness, analgesia, anticonvulsant action; Ability cerebral blood flow increasing amount reduces cerebral vascular resistance, slightly shrinks cerebrovascular, increases the coronary vasodilator flow; Can bring high blood pressure down, decreased heart rate has protective effect to myocardial ischemia; Gastrodia elata polysaccharide has immunocompetence.
Flos Chrysanthemi Indici is slightly cold, and is hot, bitter; Return lung, Liver Channel.Heat-clearing and toxic substances removing; The dispelling wind suppressing the hyperactive liver.
Fructus Leonuri, acrid in the mouth, hardship, cold nature.GUIXIN bag, Liver Channel.
Preparation and instructions of taking: the impurity place to go with each crude drug is decocted in water for oral dose potion on the one.Ten days is a course of treatment.
Clinical observation shows after taking three courses of treatment:
The treatment standard: 1 cures: high pressure≤140mmHg, and low pressure≤90mmHg, drug withdrawal blood pressure does not after two months rebound;
2 is effective: high pressure≤140mmHg, and low pressure≤90mmHg, drug withdrawal blood pressure after two months has a rebound;
3 is invalid;
Adopt hypertension therapy clinical statistics of the present invention: treatment hypertension 200 examples, wherein male 49-60 year totally 121 examples, account for 34 examples more than 60 years old, account for 45 examples in women 45-67 year.After taking three courses of treatment, clinical treatment 200 examples are cured 125 examples, and drug withdrawal blood pressure does not after two months normally rebound, and 2 months bleeding from anus of cure rate 62.5%, 75 routine drug withdrawal extrude existing bounce-back, effective percentage 37.5%, total effective rate 100%, inefficiency 0.
The specific embodiment
Embodiment 1:
With Hirudo 6g, Rhizoma Gastrodiae 2g, Concha Haliotidis 10g, Ramulus Uncariae Cum Uncis 8g, Flos Chrysanthemi Indici 9g, Radix seu Herba Tetrastigmatis Hypoglauci 3g; Radix Salviae Miltiorrhizae 5g, Fructus Leonuri 1g, Fructus Schisandrae Chinensis 7g, Radix Paeoniae Alba 2g, Radix Puerariae 5g, Rhizoma Chuanxiong 3g; Flos Carthami 2g adds water 1000ml and decocts, and the elimination slag becomes the 500ml decoction, takes every day once, and ten days is a course of treatment.
Embodiment 2:
With Hirudo 10g, Rhizoma Gastrodiae 4g, Concha Haliotidis 20g, Ramulus Uncariae Cum Uncis 10g, Flos Chrysanthemi Indici 10g, Radix seu Herba Tetrastigmatis Hypoglauci 5g; Radix Salviae Miltiorrhizae 10g, Fructus Leonuri 2g, Fructus Schisandrae Chinensis 10g, Radix Paeoniae Alba 4g, Radix Puerariae 10g, Rhizoma Chuanxiong 6g; Flos Carthami 4g adds water 1000ml and decocts, and the elimination slag becomes the 500ml decoction, takes every day once, and ten days is a course of treatment.
Embodiment 3:
With Hirudo 8g, Rhizoma Gastrodiae 3g, Concha Haliotidis 15g, Ramulus Uncariae Cum Uncis 9g, Flos Chrysanthemi Indici 9g, Radix seu Herba Tetrastigmatis Hypoglauci 4g; Radix Salviae Miltiorrhizae 7g, Fructus Leonuri 1g, Fructus Schisandrae Chinensis 8g, Radix Paeoniae Alba 3g, Radix Puerariae 6g, Rhizoma Chuanxiong 4g; Flos Carthami 3g adds water 1000ml and decocts, and the elimination slag becomes the 500ml decoction, takes every day once, and ten days is a course of treatment.
Claims (2)
1. the hypertensive Chinese medicine composition of treatment is characterized in that, is to be processed by the component of following parts by weight: Hirudo 6-10 part, Rhizoma Gastrodiae 2-4 part; Concha Haliotidis 10-20 part, Ramulus Uncariae Cum Uncis 8-10 part, Flos Chrysanthemi Indici 9-10 part, Radix seu Herba Tetrastigmatis Hypoglauci 3-5 part; Radix Salviae Miltiorrhizae 5-10 part, Fructus Leonuri 1-2 part, Fructus Schisandrae Chinensis 7-10 part, Radix Paeoniae Alba 2-4 part; Radix Puerariae 5-10 part, Rhizoma Chuanxiong 3-6 part, Flos Carthami 2-4 part.
2. the hypertensive Chinese medicine composition of treatment as claimed in claim 1, it is characterized in that: the parts by weight of each component are following: 8 parts of Hirudos, 3 parts in Rhizoma Gastrodiae, 15 parts of Concha Haliotidis; 9 parts of Ramulus Uncariae Cum Unciss, 9 parts of Flos Chrysanthemi Indicis, 4 parts of Radix seu Herba Tetrastigmatis Hypoglaucis, 7 parts of Radix Salviae Miltiorrhizaes; 1 part of Fructus Leonuri, 8 parts of Fructus Schisandrae Chinensis, 3 parts of Radix Paeoniae Alba; 6 parts of Radix Puerariaes, 4 parts of Rhizoma Chuanxiongs, 3 parts on Flos Carthami.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210036816 CN102526511B (en) | 2012-02-20 | 2012-02-20 | Chinese medicinal composition for treating hypertension |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210036816 CN102526511B (en) | 2012-02-20 | 2012-02-20 | Chinese medicinal composition for treating hypertension |
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| Publication Number | Publication Date |
|---|---|
| CN102526511A true CN102526511A (en) | 2012-07-04 |
| CN102526511B CN102526511B (en) | 2013-08-21 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201210036816 Active CN102526511B (en) | 2012-02-20 | 2012-02-20 | Chinese medicinal composition for treating hypertension |
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| Country | Link |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106689927A (en) * | 2016-12-05 | 2017-05-24 | 成都鼎信致远科技有限公司 | Gastrodia elata beverage and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1390580A (en) * | 2002-05-16 | 2003-01-15 | 段登奎 | 'Naoxinkang' capsule for treating hypertension |
| CN1868532A (en) * | 2005-05-23 | 2006-11-29 | 邓大勇 | Medicine for treating hypertension |
| CN101062125A (en) * | 2007-05-29 | 2007-10-31 | 沈信堂 | Chinese medicine for treating hypertension |
| CN101085233A (en) * | 2007-06-13 | 2007-12-12 | 夏熙邦 | Civil Chinese medicinal herb with hypotensive, antilipemic and hypoylycemic function |
-
2012
- 2012-02-20 CN CN 201210036816 patent/CN102526511B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1390580A (en) * | 2002-05-16 | 2003-01-15 | 段登奎 | 'Naoxinkang' capsule for treating hypertension |
| CN1868532A (en) * | 2005-05-23 | 2006-11-29 | 邓大勇 | Medicine for treating hypertension |
| CN101062125A (en) * | 2007-05-29 | 2007-10-31 | 沈信堂 | Chinese medicine for treating hypertension |
| CN101085233A (en) * | 2007-06-13 | 2007-12-12 | 夏熙邦 | Civil Chinese medicinal herb with hypotensive, antilipemic and hypoylycemic function |
Non-Patent Citations (1)
| Title |
|---|
| 刘威等: "五味子对心血管系统作用的研究", 《北华大学学报》, vol. 12, no. 1, 28 February 2011 (2011-02-28), pages 48 - 1 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106689927A (en) * | 2016-12-05 | 2017-05-24 | 成都鼎信致远科技有限公司 | Gastrodia elata beverage and preparation method thereof |
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| Publication number | Publication date |
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| CN102526511B (en) | 2013-08-21 |
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| Date | Code | Title | Description |
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| PB01 | Publication | ||
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| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: NANTONG HONGCI PHARMACEUTICAL CO., LTD. Free format text: FORMER OWNER: HU KEDING Effective date: 20140616 |
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| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 315318 NINGBO, ZHEJIANG PROVINCE TO: 226200 NANTONG, JIANGSU PROVINCE |
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| TR01 | Transfer of patent right |
Effective date of registration: 20140616 Address after: 226200 chemical industry park, Nantong, Qidong, Jiangsu Patentee after: NANTONG HONGCI PHARMACEUTICAL CO., LTD. Address before: 315318 Wu Meicun, Henghe Town, Cixi, Zhejiang Patentee before: Hu Keding |