CN102526508A - Medicament for treating type II diabetes - Google Patents

Medicament for treating type II diabetes Download PDF

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Publication number
CN102526508A
CN102526508A CN2012100129884A CN201210012988A CN102526508A CN 102526508 A CN102526508 A CN 102526508A CN 2012100129884 A CN2012100129884 A CN 2012100129884A CN 201210012988 A CN201210012988 A CN 201210012988A CN 102526508 A CN102526508 A CN 102526508A
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CN
China
Prior art keywords
medicine
diabetes
radix
treatment
type
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Pending
Application number
CN2012100129884A
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Chinese (zh)
Inventor
朱恩灿
魏渊源
邢斌
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Cheng Siyuan Biotechnology (shanghai) Co Ltd
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Cheng Siyuan Biotechnology (shanghai) Co Ltd
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Priority to CN2012100129884A priority Critical patent/CN102526508A/en
Publication of CN102526508A publication Critical patent/CN102526508A/en
Pending legal-status Critical Current

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Abstract

The invention discloses a medicament for treating type II diabetes, which comprises the following raw materials in parts by weight: 30-40 of Dendrobium officinale, 10-30 of Radix Codonopsis, 6-12 of Gastrodia elata, 2-20 of Equus asinus hide, 15-30 of lotus root, 10-20 of Schisandra chinensis fruit, 6-15 of Radix Trichosanthis, 6-15 of talc, 15-30 of gypsum, 6-20 of Radix Puerariae, 6-18 of Lycium chinesis fruit, 3-6 of Ophiopogon japonicus and 10-30 of Dioscorea opposita. The invention has the benefits as follows: the medicament is designed based on the diabetes diagnosis principle in Chinese medicine and properties of different types of Chinese herbs, is formulated in appropriate dosage forms by prescription compatibility, has a good hypoglycemic function, and can be used for treating diabetes with a high effective rate up to 88.8%.

Description

A kind of medicine of treating type ii diabetes
Technical field
The present invention relates to be used to treat the medicine of type ii diabetes, the Chinese patent medicine that specifically uses Chinese herbal medicine to form as feedstock production, the present invention also designs the method for preparing of this medicine.
Background technology
According to statistics, global diabetics has people more than 200,000,000, in state-owned 2,000 ten thousand.Diabetes threaten increasing to human beings'health and life.In developed country, diabetes become causing death's the 4th reason.To treatment of diabetes, gene therapy also only is the displaying of rosy prospect in theory, and the probability international medical community of operative treatment is carrying out conscientious exploration, and the method for reality also is to use Drug therapy.Modern medicine divides diabetes into insulin-dependent and non-insulin one die two types, and the former is called type i diabetes, must use insulin and treat; The latter is called type ii diabetes, and insulin can not be used in its treatment.The present invention is to type ii diabetes.
Physician of all times has created the effective medicine of a large amount of treatment diabetes, but does not still have a kind of medicine that generally is suitable for, can cures diabetes at all so far.Most medicines are that too high blood glucose is lowered, and glucose in urine reduces or turns out cloudy, and relapse rate is very high after the drug withdrawal.Viewpoint according to Chinese medicine belongs to " curing the symptoms, not the disease ".Some medicines also are easy to generate drug resistance, and a patient just must change types of drugs after certain medicine of use reaches certain hour, just can keep curative effect.Therefore, the medicine of seeking new efficacious therapy diabetes remains a task of medical circle.Particularly have no side effect, can fundamentally improve patient's whole body function status, clinical treatment is required especially to have the medicine of late result.
Summary of the invention
The objective of the invention is can improve patient's whole body functional condition for a kind of medicine of treating type ii diabetes is provided, late result is medicine preferably.It also has cost characteristics lower, easy to use simultaneously.
Another object of the present invention provides the method for preparing of this medicine.
A kind of medicine of treating type ii diabetes is made up of the raw material of following weight portion: Herba Dendrobii 30-40; Radix Codonopsis 10-30; Rhizoma Gastrodiae 6-12; Colla Corii Asini 2-20; Rhizoma Nelumbinis 15-30; Fructus Schisandrae Chinensis 10-20; Radix Trichosanthis 6-15; Talcum 6-15; Gypsum Fibrosum 15-30; Radix Puerariae 6-20; Fructus Lycii 6-18; Radix Ophiopogonis 3-6; Rhizoma Dioscoreae 10-30.
By above component, medicine of the present invention can be processed powder, tablet, pill, capsule, granular pattern electuary, oral liquor and other types of formulations by usual way.Wherein be preferably the granular pattern electuary.
The method for preparing the granular pattern electuary is with high pressure decoction behind each medicine pulverize separately, each decocted liquid medicine to be merged, filter, be condensed into graininess be finished product.
The method for preparing water pill is that with each medicine pulverize separately overpopulation sieve, each medicated powder powder mixes is even, and water is general to be ball, is finished product after the drying.
More than various dosage forms each oral dose of being grown up be equivalent to crude drug 10-15 gram approximately, divides and takes for 2-4 time, generally logotype 35 days was a course of treatment.It is of the present invention one big characteristics that various dosage forms all do not have bitterness.
The present invention has following beneficial effect: the present invention is based on motherland's medical science to dialectical theoretical of diabetes with to the understanding of the multiple Chinese herbal medicine property of medicine, through the types of drugs compatibility, processes suitable dosage form, has good function of blood sugar reduction.
The specific embodiment
Further set forth technical characterstic of the present invention below in conjunction with embodiment.
1, preparation electuary
Embodiment 1
Take by weighing following raw material: Herba Dendrobii 3000g, Radix Codonopsis 2000g, Rhizoma Gastrodiae 800g, Colla Corii Asini 1000g, Rhizoma Nelumbinis 2200g, Fructus Schisandrae Chinensis 1500g, Radix Trichosanthis 1000g, Talcum 1000g, Gypsum Fibrosum 2500g, Radix Puerariae 1200g, Fructus Lycii 1500g, Radix Ophiopogonis 500g, Rhizoma Dioscoreae 2000g.
Embodiment 2
Herba Dendrobii 4000g; Radix Codonopsis 3000g; Rhizoma Gastrodiae 1000g; Colla Corii Asini 2000g; Rhizoma Nelumbinis 3000g; Fructus Schisandrae Chinensis 2000g; Radix Trichosanthis 1500g; Talcum 1500g; Gypsum Fibrosum 3000g; Radix Puerariae 2000g; Fructus Lycii 1500g; Radix Ophiopogonis 300g; Rhizoma Dioscoreae 3000g.
Embodiment 3
Herba Dendrobii 3500g; Radix Codonopsis 1000g; Rhizoma Gastrodiae 600g; Colla Corii Asini 200g; Rhizoma Nelumbinis 1500g; Fructus Schisandrae Chinensis 1000g; Radix Trichosanthis 600g; Talcum 600g; Gypsum Fibrosum 1500g; Radix Puerariae 600g; Fructus Lycii 800g; Radix Ophiopogonis 600g; Rhizoma Dioscoreae 1000g.
Each medicine is cleaned, sorts initial processing, and behind the pulverize separately, each medicine high pressure decocts 3 times, and each decoction liquor 1-2 hour, get each decocted liquid medicine of each time and merge, filter, be condensed into graininess and be finished product.
This granular pattern electuary each oral 6-8g that is grown up, every day 3 times.General 35 days is a course of treatment.
2, preparation water pill
Embodiment 4:
Take by weighing following medicine: Herba Dendrobii 3000g, Radix Codonopsis 1200g, Rhizoma Gastrodiae 1100g, Colla Corii Asini 2000g, Rhizoma Nelumbinis 1500g, Fructus Schisandrae Chinensis 1500g, Radix Trichosanthis 600g, Talcum 1000g, Gypsum Fibrosum 3000g, Radix Puerariae 1200g, Fructus Lycii 1500g, Radix Ophiopogonis 400g, Rhizoma Dioscoreae 2800g.
Embodiment 5:
Herba Dendrobii 3000g; Radix Codonopsis 1000g; Rhizoma Gastrodiae 1000g; Colla Corii Asini 1600g; Rhizoma Nelumbinis 1800g; Fructus Schisandrae Chinensis 1600g; Radix Trichosanthis 1000g; Talcum 1500g; Gypsum Fibrosum 2500g; Radix Puerariae 1500g; Fructus Lycii 1500g; Radix Ophiopogonis 500g; Rhizoma Dioscoreae 1500g.
Embodiment 6:
Herba Dendrobii 3500g; Radix Codonopsis 1200g; Rhizoma Gastrodiae 1000g; Colla Corii Asini 800g; Rhizoma Nelumbinis 2000g; Fructus Schisandrae Chinensis 1200g; Radix Trichosanthis 1200g; Talcum 1200g; Gypsum Fibrosum 2500g; Radix Puerariae 1500g; Fructus Lycii 1200g; Radix Ophiopogonis 400g; Rhizoma Dioscoreae 1200g.
After above each material medicine cleaned, sorts initial processing, pulverize separately was crossed 400 order dusting covers, and with each medicated powder end mix homogeneously, the big piller of the general one-tenth Semen phaseoli radiati of water is finished product after the drying.Each oral 11-16g that is grown up, every day three times.General 35 days one courses of treatment.
During 1998 to 2005, use the hundreds of examples of Drug therapy II type of the present invention (non-insulin-depending type) diabetics, select that wherein the data note is following at 750 more complete routine statistical analysiss: male's 440 examples wherein, women's 310 examples; The oldest person 89 years old, minimum 21 years old; 1-3 person's 78 examples, person's 672 examples more than 3 years.
Selected patient all meets following diagnostic criteria: 1. fasting glucose is higher than 140mg%; 2. glucose in urine is positive; 3. tangible clinical symptoms is arranged.
Therapeutic Method does, the patient takes medicine of the present invention every day 2-4 time, and 35 days is a course of treatment.Three courses of treatment are observed in the treatment of this group case.Take cooperate during this medicine with keep on a diet, appropriate exercise, withdraw other all Chinese medicine and western medicine hypoglycemic medicines.
Curative effect is judged by following standard:
Produce effects---1. clinical symptom disappearance; 2. fasting glucose was reduced in normal range; 3. glucose in urine is turned out cloudy.
Effectively---1. clinical symptom disappearance; 2. fasting glucose is fallen more than the 60mg%; 3. glucose in urine is controlled at (+).
Invalid---three of medications are more than the course of treatment, and 1. clinical symptoms does not have significant change; 2. fasting glucose is still in abnormal level; 3. the glucose in urine control is more than (++).
This organizes 750 routine therapeutic outcomes, produce effects 677 examples (39.8%), and 52 examples that take a turn for the better (49.0%), invalid 31 examples (11.2%), total effective rate is 88.8%.

Claims (6)

1. medicine of treating type ii diabetes, it is characterized in that: the raw material by following weight portion is formed: Herba Dendrobii 30-40; Radix Codonopsis 10-30; Rhizoma Gastrodiae 6-12; Colla Corii Asini 2-20; Rhizoma Nelumbinis 15-30; Fructus Schisandrae Chinensis 10-20; Radix Trichosanthis 6-15; Talcum 6-15; Gypsum Fibrosum 15-30; Radix Puerariae 6-20; Fructus Lycii 6-18; Radix Ophiopogonis 3-6; Rhizoma Dioscoreae 10-30.
2. the medicine of treatment type ii diabetes according to claim 1 is characterized in that: can process powder, tablet, pill, capsule, granular pattern electuary and oral liquid formulation by usual way.
3. the medicine of treatment type ii diabetes according to claim 2 is characterized in that: can process granular pattern electuary or water pill by usual way.
4. the medicine of treatment type ii diabetes according to claim 2 is characterized in that: the method for preparing the granular pattern electuary is with high pressure decoction behind each medicine pulverize separately, each decocted liquid medicine to be merged, filter, be condensed into graininess be finished product; The method for preparing water pill is that with each medicine pulverize separately overpopulation sieve, each medicated powder powder mixes is even, and water is general to be ball, is finished product after the drying.
5. the medicine of treatment type ii diabetes according to claim 1 is characterized in that: more than various dosage forms each oral dose of being grown up be equivalent to crude drug 10-15 gram, divide and take for 2-4 time, logotype 35 days was a course of treatment.
6. the medicine of treatment type ii diabetes according to claim 1 is characterized in that: the medicine that is applied to treat type ii diabetes.
CN2012100129884A 2012-01-16 2012-01-16 Medicament for treating type II diabetes Pending CN102526508A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112426488A (en) * 2020-12-03 2021-03-02 遵义医科大学 Traditional Chinese medicine composition for reducing blood sugar and preparation method and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1308949A (en) * 2000-09-11 2001-08-22 蹇利明 Medicine for treating diabetes and its preparing process

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1308949A (en) * 2000-09-11 2001-08-22 蹇利明 Medicine for treating diabetes and its preparing process

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
施红等: "石斛合剂对2型糖尿病的临床疗效观察", 《中药新药与临床药理》 *
沈丕安: "《补益中药的临床运用》", 31 August 2008, 第二军医大学出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112426488A (en) * 2020-12-03 2021-03-02 遵义医科大学 Traditional Chinese medicine composition for reducing blood sugar and preparation method and application thereof

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Application publication date: 20120704