CN102525458A - Device for monitoring hydrocephalus and encephaledema - Google Patents
Device for monitoring hydrocephalus and encephaledema Download PDFInfo
- Publication number
- CN102525458A CN102525458A CN2012100457215A CN201210045721A CN102525458A CN 102525458 A CN102525458 A CN 102525458A CN 2012100457215 A CN2012100457215 A CN 2012100457215A CN 201210045721 A CN201210045721 A CN 201210045721A CN 102525458 A CN102525458 A CN 102525458A
- Authority
- CN
- China
- Prior art keywords
- hydrocephalus
- electromagnetic wave
- signal
- electromagnetic
- cerebral edema
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Landscapes
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Abstract
The invention relates to a device for monitoring hydrocephalus and encephaledema. The device comprises a signal encoding generator, an emitting electrode, a receiving electrode, a signal processing digital converter, an orthogonality regulator, a detector, a parameter evaluator, an impedance analysis instrument and an evaluation instrument. After passing through the human brain, electromagnetic waves change, by comparing attenuation coefficients, relative phase shifts, spreading time differences and complex wave values K of the electromagnetic waves before and after the electromagnetic waves enter the human brain, the specific conditions of the hydrocephalus and encephaledema be can evaluated, the method is different from the traditional invasion detection method, the device can be used for realizing 24-hour monitoring, so that the medical safety in treatment of hydrocephalus and encephaledema is obviously improved.
Description
Technical field
The present invention relates to a kind of medical apparatus and instruments, the hydrocephalic medical apparatus and instruments of particularly a kind of monitoring.
Background technology
The known condition of hydrocephalus is at the encephalocoele or the ventricles of the brain, the excessive buildup of cerebrospinal fluid (CSF).Under normal circumstances, cerebrospinal fluid is that the running of brain is most important.Carry nutrient and refuse from brain, and create the neonychium of a liquid.But the excessive accumulation of cerebrospinal fluid is to the disproportionate pressure of brain, and possibly cause brain cell and tissue injury.Therefore, medical condition, the proper flow that the absorption of directly interrupting cerebrospinal fluid gets into blood finally causes hydrocephalus with to create cerebrospinal fluid too much.
The human potential that hydrocephalus influences institute's has age can be divided into two big types with classification: obtain the congenital hydrocephalus and the day after tomorrow hydrops.Congenital hydrocephalus is when birth, can be in the gene unconventionality of the growth and development stage of fetus, premature labor, or the result of influence.By contrast, obtaining hydrops the day after tomorrow is that some body reason pathological changes of people causes, but is not limited only to angiopathy, injury of head or injury of head.Cause adult's apoplexy, hemorrhage, or the hydrops of these two categories of brain trauma, be called as ultravacuum hydrocephalus and normal pressure hydrocephalus (NPH).
Though hydrocephalus citizen situation is not registered by country, the data that draw after through the assessment to some are significant to the assessment of national population.The ramose institute of NIH's neurological disorders and apoplexy estimates, approximately just have among per 500 children 1 congenital ill.And nearest statistical data shows, NPH is exactly the origin of dementia, and 5% people suffers from dementia among patient NPH more than 70 years old.
During diagnosis of cerebral hydrops, most of doctors utilize Cranial Computed Tomography or MRI scanning.On the other hand, monitoring technology mainly comprises invasive method at present, and like monitoring intracranial pressure, waist is worn (LP), or uses and in cerebrospinal fluid, insert the impedance of electrode measurement cerebrospinal fluid.In these programs, a hole is essential, and with assessment intracranial environment, LP can cause that cerebral hernia is dead sometimes.Recently, developed the hydrocephalic technology of non-invasive assessment based on the TCD,transcranial Doppler (TCS) of medical supersonic technology, but said method does not all provide 24 hours bedside monitorings.
Another similar situation, hydrocephalus, cerebral edema.The cerebral edema brain injury, wound and infection etc., may cause expanding behind similar our ankle or the knee injury with redundant moisture from cerebral tissue swelling.Yet unlike our ankle or knee, our brain is to surround thick and hard skull, does not leave enough expansion leeway, thereby causes intracranial pressure to increase.If can't discern with undressed, cerebral edema can cause nonvolatil injury or death., in CICU continuous monitoring hydrocephalus 24 hours every days and cerebral edema, this is desirable method and system in patient's bedside.This system needs cost low, is easy to use, and allows monitoring and minimum of interference automatically.
Summary of the invention
The object of the invention just provides a kind of device that is used to monitor hydrocephalus and cerebral edema, can use the 24 hours monitoring and evaluation hydrocephaluss of mode of non-invasion and the situation of cerebral edema through it, reduces the treatment risk.
The objective of the invention is to realize that through such technical scheme it includes signal code generator, emission electrode, collecting electrode, signal processing digital converter, quadrature actuator, detector, parameter evaluation device, electric impedance analyzer and assessment appearance,
The signal code generator; Be used to generate electromagnetic wave, and initial amplitude of recording electromagnetic wave
and initial phase
;
Emission electrode is to the human brain electromagnetic wave that coding take place to produce that transmits;
Collecting electrode receives the electromagnetic wave that emission electrode sent through human brain;
The signal processing digital converter, the electromagnetic wave that collecting electrode is received amplifies and Filtering Processing, is digital signal with analog signal conversion again;
The quadrature actuator; To the signal of telecommunication orthogonalization process that the signal processing digitizer processes is crossed, obtain signal
and orthogonal signalling
in the same way;
Detector detects electromagnetic signal in the same way
and orthogonal signalling
;
The parameter evaluation device calculates relative damping coefficient
, relative phase shift
, propagation time difference
and complex wave value K;
Electric impedance analyzer according to the signal of telecommunication that obtains after the signal processing digitizer processes, is measured complex impedance Z and electric capacity;
The assessment appearance, the parameter that obtains according to parameter evaluation device and electric impedance analyzer carries out hydrocephalus and cerebral edema is assessed.
Further, the parameter evaluation device calculates attenuation quotient
through following formula
Further, the parameter evaluation device calculates relative phase shift
through following formula
Further, the parameter evaluation device calculates propagation time difference
through following formula
In the formula;
electromagnetic wave propagation speed for receiving,
is the electromagnetic wave propagation speed of emission.
Further, the electromagnetic wave that produced of said signal code generator includes the coding ripple of continuous monochromatic, multi-frequency wideband pulse and assigned frequency and wave mode.
Further, to be positioned at brain subcutaneous for said emission electrode and collecting electrode.
Owing to adopted technique scheme, the present invention to have following advantage:
Electromagnetic wave is through behind the human brain; Change has taken place; Through before the comparison electromagnetic wave entering human brain and through attenuation quotient
, relative phase shift
, propagation time difference
and complex wave value K behind the human brain; Can assess the concrete condition of hydrocephalus and cerebral edema; Be different from the traditional invasive monitoring method; The present invention can realize monitoring in 24 hours, has significantly increased the medical safety property of hydrocephalus and cerebral edema.
Other advantages of the present invention, target and characteristic will be set forth in description subsequently to a certain extent; And to a certain extent; Based on being conspicuous to those skilled in the art, perhaps can from practice of the present invention, obtain instruction to investigating of hereinafter.Target of the present invention and other advantages can realize and obtain through following description and claims.
Description of drawings
Description of drawings of the present invention is following.
Fig. 1 is a structural representation of the present invention.
The specific embodiment
Below in conjunction with accompanying drawing and embodiment the present invention is described further.
Be used to monitor the device of hydrocephalus and cerebral edema, said device includes signal code generator, emission electrode, collecting electrode, signal processing digital converter, quadrature actuator, detector, parameter evaluation device, electric impedance analyzer and assessment appearance,
The signal code generator; Be used to generate electromagnetic wave, and initial amplitude of recording electromagnetic wave
and initial phase
;
Emission electrode is to the human brain electromagnetic wave that coding take place to produce that transmits;
Collecting electrode receives the electromagnetic wave that emission electrode sent through human brain;
The signal processing digital converter, the electromagnetic wave that collecting electrode is received amplifies and Filtering Processing, is digital signal with analog signal conversion again;
The quadrature actuator; To the signal of telecommunication orthogonalization process that the signal processing digitizer processes is crossed, obtain signal
and orthogonal signalling
in the same way;
Detector detects electromagnetic signal in the same way
and orthogonal signalling
;
The parameter evaluation device calculates relative damping coefficient
, relative phase shift
, propagation time difference
and complex wave value K;
Electric impedance analyzer according to the signal of telecommunication that obtains after the signal processing digitizer processes, is measured complex impedance Z and electric capacity;
The assessment appearance, the parameter that obtains according to parameter evaluation device and electric impedance analyzer carries out hydrocephalus and cerebral edema is assessed.
The present invention generates electromagnetic waves through the signal code generator; Emission electrode sends electromagnetic wave, and electromagnetic wave changes through human brain, and collecting electrode receives the electromagnetic wave after changing; Amplification and Filtering Processing through the signal processing digital converter convert digital signal again to.Digital signal is regulated through the quadrature actuator, detects through the electromagnetic parameter behind the human brain through detector again, and the parameter that the combined impedance analyser obtains is carried out the assessment of hydrocephalus and cerebral edema.
Through the resulting change of the propagation of electromagnetic wave in human brain; The principle that hydrocephalus and cerebral edema are assessed is: dielectric constant that cerebrospinal fluid, alba and ectocinerea are different in the human brain and conductivity; The electric conductivity of cerebrospinal fluid does not have than alba and ectocinerea; The electric medium constant of cerebrospinal fluid is lower than alba and ectocinerea, and electromagnetic wave propagation is relevant with dielectric constant and conductivity, can distinguish cerebrospinal fluid in the human brain through electromagnetic change; Thereby be used for estimating the content of cerebrospinal fluid, carry out the assessment of hydrocephalus and brain water kind.Device according to the invention is non-invasion formula, and it is subcutaneous that emission electrode and collecting electrode only need be positioned at brain.
The electromagnetic wave that said signal code generator is produced includes the coding ripple of continuous monochromatic, multi-frequency wideband pulse and assigned frequency and wave mode.
The present invention can assess the concrete condition of hydrocephalus and cerebral edema through above-mentioned work, is different from the traditional invasive monitoring method, and the present invention can realize monitoring in 24 hours, has significantly increased the medical safety property of hydrocephalus and cerebral edema.Its concrete computational methods are following:
The parameter evaluation device calculates attenuation quotient
through following formula
is propagation distance in the formula;
electromagnetic empty ripple for receiving;
is the electromagnetic empty ripple of emission, and
is the electromagnetic wave angular frequency.
The parameter evaluation device calculates relative phase shift
through following formula
The parameter evaluation device calculates propagation time difference
through following formula
In the formula;
electromagnetic wave propagation speed for receiving,
is the electromagnetic wave propagation speed of emission.
Explanation is at last; Above embodiment is only unrestricted in order to technical scheme of the present invention to be described; Although with reference to preferred embodiment the present invention is specified, those of ordinary skill in the art should be appreciated that and can make amendment or be equal to replacement technical scheme of the present invention; And not breaking away from the aim and the scope of present technique scheme, it all should be encompassed in the middle of the claim scope of the present invention.
Claims (6)
1. be used to monitor the device of hydrocephalus and cerebral edema; It is characterized in that: said device includes signal code generator, emission electrode, collecting electrode, signal processing digital converter, quadrature actuator, detector, parameter evaluation device, electric impedance analyzer and assessment appearance
The signal code generator; Be used to generate electromagnetic wave, and initial amplitude of recording electromagnetic wave
and initial phase
;
Emission electrode is to the human brain electromagnetic wave that coding take place to produce that transmits;
Collecting electrode receives the electromagnetic wave that emission electrode sent through human brain;
The signal processing digital converter, the electromagnetic wave that collecting electrode is received amplifies and Filtering Processing, is digital signal with analog signal conversion again;
The quadrature actuator; To the signal of telecommunication orthogonalization process that the signal processing digitizer processes is crossed, obtain signal
and orthogonal signalling
in the same way;
Detector detects electromagnetic signal in the same way
and orthogonal signalling
;
The parameter evaluation device calculates relative damping coefficient
, relative phase shift
, propagation time difference
and complex wave value K;
Electric impedance analyzer according to the signal of telecommunication that obtains after the signal processing digitizer processes, is measured complex impedance Z and electric capacity;
The assessment appearance, the parameter that obtains according to parameter evaluation device and electric impedance analyzer carries out hydrocephalus and cerebral edema is assessed.
2. the device that is used to monitor hydrocephalus and cerebral edema as claimed in claim 1 is characterized in that: the parameter evaluation device calculates attenuation quotient
through following formula
3. the device that is used to monitor hydrocephalus and cerebral edema as claimed in claim 1 is characterized in that: the parameter evaluation device calculates relative phase shift
through following formula
4. like 1, the 2 or 3 described devices that are used to monitor hydrocephalus and cerebral edema, it is characterized in that: the parameter evaluation device calculates propagation time difference
through following formula
In the formula;
electromagnetic wave propagation speed for receiving,
is the electromagnetic wave propagation speed of emission.
5. the device that is used to monitor hydrocephalus and cerebral edema as claimed in claim 1 is characterized in that: the electromagnetic wave that said signal code generator is produced includes the coding ripple of continuous monochromatic, multi-frequency wideband pulse and assigned frequency and wave mode.
6. the device that is used to monitor hydrocephalus and cerebral edema as claimed in claim 1 is characterized in that: it is subcutaneous that said emission electrode and collecting electrode are positioned at brain.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210045721 CN102525458B (en) | 2012-02-27 | 2012-02-27 | Device for monitoring hydrocephalus and encephaledema |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210045721 CN102525458B (en) | 2012-02-27 | 2012-02-27 | Device for monitoring hydrocephalus and encephaledema |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102525458A true CN102525458A (en) | 2012-07-04 |
| CN102525458B CN102525458B (en) | 2013-11-06 |
Family
ID=46334424
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201210045721 Active CN102525458B (en) | 2012-02-27 | 2012-02-27 | Device for monitoring hydrocephalus and encephaledema |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102525458B (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579008A (en) * | 2012-02-27 | 2012-07-18 | 重庆博恩富克医疗设备有限公司 | Device and method for monitoring hydrocephalus and encephaledema |
| CN103110408A (en) * | 2013-03-14 | 2013-05-22 | 重庆大学 | Encephaledema monitoring device |
| CN104257382A (en) * | 2014-09-11 | 2015-01-07 | 东北大学 | Electromagnetic wave propagation speed based biological tissue electromagnetic parameter imaging device and method |
| CN104720800A (en) * | 2015-04-15 | 2015-06-24 | 重庆博恩富克医疗设备有限公司 | Electromagnetic wave signal processing device |
| CN105769190A (en) * | 2016-03-29 | 2016-07-20 | 重庆大学 | Device for detecting cephalophyma and encephaledema |
| CN106603107A (en) * | 2016-12-21 | 2017-04-26 | 惠州Tcl移动通信有限公司 | Head-mounted device and control method thereof |
| CN109363631A (en) * | 2018-07-27 | 2019-02-22 | 河北大艾智能科技股份有限公司 | A kind of tissue health monitor method, terminal device and system |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1419889A (en) * | 2002-07-24 | 2003-05-28 | 重庆博恩科技有限公司 | Method for non-invasive clinical monitoring intracranial edema |
| US20070067123A1 (en) * | 2005-09-19 | 2007-03-22 | Jungerman Roger L | Advanced arbitrary waveform generator |
| CN102159129A (en) * | 2008-07-18 | 2011-08-17 | 耐卡拉特两合公司 | System for regulating intracranial pressure |
| CN102579008A (en) * | 2012-02-27 | 2012-07-18 | 重庆博恩富克医疗设备有限公司 | Device and method for monitoring hydrocephalus and encephaledema |
| CN202875327U (en) * | 2012-02-27 | 2013-04-17 | 重庆博恩富克医疗设备有限公司 | Device for monitoring hydrocephalus and encephaledema |
-
2012
- 2012-02-27 CN CN 201210045721 patent/CN102525458B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1419889A (en) * | 2002-07-24 | 2003-05-28 | 重庆博恩科技有限公司 | Method for non-invasive clinical monitoring intracranial edema |
| US20070067123A1 (en) * | 2005-09-19 | 2007-03-22 | Jungerman Roger L | Advanced arbitrary waveform generator |
| CN102159129A (en) * | 2008-07-18 | 2011-08-17 | 耐卡拉特两合公司 | System for regulating intracranial pressure |
| CN102579008A (en) * | 2012-02-27 | 2012-07-18 | 重庆博恩富克医疗设备有限公司 | Device and method for monitoring hydrocephalus and encephaledema |
| CN202875327U (en) * | 2012-02-27 | 2013-04-17 | 重庆博恩富克医疗设备有限公司 | Device for monitoring hydrocephalus and encephaledema |
Non-Patent Citations (2)
| Title |
|---|
| 王健等: "无创性阻抗法检测脑水肿的可行性研究", 《中华物理医学与康复杂志》, vol. 27, no. 08, 31 December 2005 (2005-12-31) * |
| 霍旭阳等: "一种高精度生物电阻抗测量系统的设计", 《仪器仪表学报》, vol. 28, no. 6, 31 December 2007 (2007-12-31) * |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579008A (en) * | 2012-02-27 | 2012-07-18 | 重庆博恩富克医疗设备有限公司 | Device and method for monitoring hydrocephalus and encephaledema |
| CN103110408A (en) * | 2013-03-14 | 2013-05-22 | 重庆大学 | Encephaledema monitoring device |
| CN104257382A (en) * | 2014-09-11 | 2015-01-07 | 东北大学 | Electromagnetic wave propagation speed based biological tissue electromagnetic parameter imaging device and method |
| CN104257382B (en) * | 2014-09-11 | 2016-06-29 | 东北大学 | Biological tissue's electromagnetic parameter imaging device and method based on propagation velocity of electromagnetic wave |
| CN104720800A (en) * | 2015-04-15 | 2015-06-24 | 重庆博恩富克医疗设备有限公司 | Electromagnetic wave signal processing device |
| CN105769190A (en) * | 2016-03-29 | 2016-07-20 | 重庆大学 | Device for detecting cephalophyma and encephaledema |
| CN106603107A (en) * | 2016-12-21 | 2017-04-26 | 惠州Tcl移动通信有限公司 | Head-mounted device and control method thereof |
| CN106603107B (en) * | 2016-12-21 | 2019-10-29 | Tcl移动通信科技（宁波）有限公司 | A kind of helmet and its control method |
| CN109363631A (en) * | 2018-07-27 | 2019-02-22 | 河北大艾智能科技股份有限公司 | A kind of tissue health monitor method, terminal device and system |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102525458B (en) | 2013-11-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102525458B (en) | Device for monitoring hydrocephalus and encephaledema | |
| CN102579008B (en) | Device for monitoring hydrocephalus and encephaledema | |
| US9801608B2 (en) | Apparatus and method for measuring intracranial pressure | |
| US8764672B2 (en) | System, method and device for monitoring the condition of an internal organ | |
| WO1988002234A1 (en) | Apparatus for measuring intracranial pressure | |
| JPH08504342A (en) | Apparatus and method for labor pain diagnosis | |
| KR20180103845A (en) | Ultrasonic methods and devices for respiratory monitoring | |
| Levinsky et al. | Non-invasive estimation of static and pulsatile intracranial pressure from transcranial acoustic signals | |
| US9456757B1 (en) | Noninvasive monitoring hydrocephalus, cerebral edema, and intracranial bleeding using electromagnetic wave propagation properties | |
| US11690591B2 (en) | Apparatus and methods for detecting increase in brain swelling and/or shifting | |
| CN102551715A (en) | Radio emission device for monitoring hydrocephalus and cerebral edema | |
| CN107106125B (en) | System and method for measuring arterial parameters | |
| CN103690169A (en) | Respiration information detection method and system | |
| Feng et al. | Sleeping heart monitoring using hydrogel-textile capacitive ECG electrodes | |
| CN109717835B (en) | Snore body position detection method based on microphone array | |
| IL129508A (en) | System for detecting smooth muscle motor activity and method therefor | |
| CN102579009B (en) | Electric signal processing unit for monitoring hydrocephalus and encephaledema | |
| CN202875327U (en) | Device for monitoring hydrocephalus and encephaledema | |
| CN202477660U (en) | Electrical signal processing device for monitoring hydrocephalus and encephaledema | |
| Eide et al. | Association between intracranial, arterial pulse pressure amplitudes and cerebral autoregulation in head injury patients | |
| CN202505342U (en) | Electromagnetic wave emission device for monitoring hydrocephalus and brain edema | |
| Kazimierska et al. | Analysis of intracranial pressure pulse waveform in studies on cerebrospinal compliance: a narrative review | |
| Dhar et al. | Spectral analysis of tympanic membrane pulse signal: An approach for noninvasive detection of elevated intracranial pressure | |
| CN113892931A (en) | Method for extracting and analyzing intra-abdominal pressure by FMCW radar based on deep learning | |
| CN202751392U (en) | Brain edema change measuring device based on minimum impedance frequency |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |