CN102524537A - Iron-supplementing compound and preparation method thereof - Google Patents
Iron-supplementing compound and preparation method thereof Download PDFInfo
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- CN102524537A CN102524537A CN2011104519907A CN201110451990A CN102524537A CN 102524537 A CN102524537 A CN 102524537A CN 2011104519907 A CN2011104519907 A CN 2011104519907A CN 201110451990 A CN201110451990 A CN 201110451990A CN 102524537 A CN102524537 A CN 102524537A
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- 238000002360 preparation method Methods 0.000 title claims description 14
- 150000001875 compounds Chemical class 0.000 title abstract 4
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims abstract description 188
- 229910052742 iron Inorganic materials 0.000 claims abstract description 60
- KSFOVUSSGSKXFI-GAQDCDSVSA-N CC1=C/2NC(\C=C3/N=C(/C=C4\N\C(=C/C5=N/C(=C\2)/C(C=C)=C5C)C(C=C)=C4C)C(C)=C3CCC(O)=O)=C1CCC(O)=O Chemical compound CC1=C/2NC(\C=C3/N=C(/C=C4\N\C(=C/C5=N/C(=C\2)/C(C=C)=C5C)C(C=C)=C4C)C(C)=C3CCC(O)=O)=C1CCC(O)=O KSFOVUSSGSKXFI-GAQDCDSVSA-N 0.000 claims abstract description 11
- 229950003776 protoporphyrin Drugs 0.000 claims abstract description 11
- 239000000203 mixture Substances 0.000 claims description 111
- 230000008901 benefit Effects 0.000 claims description 40
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- GIPOFCXYHMWROH-UHFFFAOYSA-L 2-aminoacetate;iron(2+) Chemical compound [Fe+2].NCC([O-])=O.NCC([O-])=O GIPOFCXYHMWROH-UHFFFAOYSA-L 0.000 claims description 20
- 229940086413 ferrous bisglycinate Drugs 0.000 claims description 20
- 229930003944 flavone Natural products 0.000 claims description 19
- 235000011949 flavones Nutrition 0.000 claims description 19
- 239000002773 nucleotide Substances 0.000 claims description 18
- 125000003729 nucleotide group Chemical group 0.000 claims description 18
- 108010024636 Glutathione Proteins 0.000 claims description 17
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- 150000004032 porphyrins Chemical class 0.000 claims description 17
- 239000013522 chelant Substances 0.000 claims description 15
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 claims description 13
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- DKKCQDROTDCQOR-UHFFFAOYSA-L Ferrous lactate Chemical compound [Fe+2].CC(O)C([O-])=O.CC(O)C([O-])=O DKKCQDROTDCQOR-UHFFFAOYSA-L 0.000 claims description 12
- FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 claims description 12
- 239000004225 ferrous lactate Substances 0.000 claims description 12
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- CWYNVVGOOAEACU-UHFFFAOYSA-N Fe2+ Chemical compound [Fe+2] CWYNVVGOOAEACU-UHFFFAOYSA-N 0.000 description 9
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- VTLYFUHAOXGGBS-UHFFFAOYSA-N Fe3+ Chemical compound [Fe+3] VTLYFUHAOXGGBS-UHFFFAOYSA-N 0.000 description 2
- PMVSDNDAUGGCCE-TYYBGVCCSA-L Ferrous fumarate Chemical compound [Fe+2].[O-]C(=O)\C=C\C([O-])=O PMVSDNDAUGGCCE-TYYBGVCCSA-L 0.000 description 2
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- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 2
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- JVXHQHGWBAHSSF-UHFFFAOYSA-L 2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate;hydron;iron(2+) Chemical compound [H+].[H+].[Fe+2].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O JVXHQHGWBAHSSF-UHFFFAOYSA-L 0.000 description 1
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- LPQOADBMXVRBNX-UHFFFAOYSA-N ac1ldcw0 Chemical compound Cl.C1CN(C)CCN1C1=C(F)C=C2C(=O)C(C(O)=O)=CN3CCSC1=C32 LPQOADBMXVRBNX-UHFFFAOYSA-N 0.000 description 1
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- 239000010941 cobalt Substances 0.000 description 1
- 229910017052 cobalt Inorganic materials 0.000 description 1
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 1
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- 235000003891 ferrous sulphate Nutrition 0.000 description 1
- 239000011790 ferrous sulphate Substances 0.000 description 1
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- BAUYGSIQEAFULO-UHFFFAOYSA-L iron(2+) sulfate (anhydrous) Chemical compound [Fe+2].[O-]S([O-])(=O)=O BAUYGSIQEAFULO-UHFFFAOYSA-L 0.000 description 1
- 229910000359 iron(II) sulfate Inorganic materials 0.000 description 1
- VRIVJOXICYMTAG-IYEMJOQQSA-L iron(ii) gluconate Chemical compound [Fe+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O VRIVJOXICYMTAG-IYEMJOQQSA-L 0.000 description 1
- FZWBNHMXJMCXLU-BLAUPYHCSA-N isomaltotriose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O)O1 FZWBNHMXJMCXLU-BLAUPYHCSA-N 0.000 description 1
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Abstract
The invention discloses an iron-supplementing compound, which comprises the following components including, by weight, 64-75 parts of organic iron, 2-4 parts of protoporphyrin and 15-18 parts of synergist. The iron-supplementing compound is suitable for livestock giving priority to pigs and poultry. The iron-supplementing compound accelerates red blood cell proliferation, improves hemoglobin synthesis and remarkably improves hematopoiesis effects. A plurality of different organic iron serves as an iron source for hematopoiesis, the iron source is absorbed by an organism to the most extent, reduction states of hemoglobin bivalent iron are protected, optimal working states of red blood cells are maintained, the bivalent iron is protected from failure caused by the fact that the bivalent iron is oxidized into trivalent iron, and maximum absorption of the bivalent iron is guaranteed.
Description
Technical field
The present invention relates to a kind of benefit Fe composition and preparation method thereof, be applicable to domestic animal, poultry.
Background technology
Iron is the essential trace element of animal, is the essential constituent of hemoglobin and myoglobins, and with cell in most of enzymes active closely related, participate in the normal transport of oxygen in the body tissue, directly influence the energy and the protein metabolism of body.
In feed and animal husbandry, the colour of skin and the yellowish pink problem of people in order to solve pig can be added a certain amount of iron usually in feed.Purpose is to want to reach the effect of enriching blood through mending iron, makes pig health ruddy, yellowish pink scarlet through enriching blood.Iron deficiency can influence the synthetic of protein and nuclifort, and then growth retardation, immunologic hypofunction take place.
In feed and animal husbandry, existing blood-nourishing and iron-replenishing technology can be divided several big type basically: one, organic acid iron and monose/polyferose.Like ferrous fumarate, ferrous lactate, polyferose, EDTA iron, ferrous gluconate, dextran iron.Because ferrous ion has obtained protection in various degree, relatively stable in enteron aisle or body fluid, this series products has higher tiring than ferrous sulfate.Two, amino acid chelated iron and composite aminoacid chelating iron.Ferrous bisglycinate chelate, ferrous methionine, hydroxy methionine are ferrous etc.Feedstuff industry is the most commonly used with ferrous bisglycinate chelate, and the several amino acids chelated iron is a kind of mixture, uncertain component content, and absorption rate is different.Three, PORPHYRIN IRON.Physianthropy is generally acknowledged the highest organic iron of absorption efficiency.Water insoluble, but independently mechanism of absorption and path had, and its price is very expensive, in feedstuff industry, does not popularize temporarily.Four, composite component.Serve as that the master adds component compositions such as organic cobalt mainly with a kind of organic iron such as ferrous fumarate.
Existing hematopoiesis technology rests in the supply of source of iron mostly, and just classification is different.But mend iron merely is to can't resolve the hematopoiesis problem, and human nutriology the 7th edition thinks, at cellular level, even the absorption of iron and storage are very sufficient, also can cause asiderosis because of not discharging or utilizing.Mending iron is exactly in order to enrich blood, and enriching blood is in order to mend red blood cell, and red blood cell is again to be formed by marrow hemopoietic stem cells division differentiation.Therefore, except iron, also have more factors can influence hematopoiesis.
Summary of the invention
The object of the present invention is to provide a kind of benefit Fe composition and preparation method thereof, be applicable to domestic animal, poultry, being particularly useful for the pig is main domestic animal, poultry.
The technical scheme that the present invention takes is:
A kind of benefit Fe composition, it contains the component of following mass parts: 64～75 parts of organic iron, 2～4 parts of protoporphyrins, 15～18 parts of synergist.
Preferably, said organic iron is at least a in polyferose, PORPHYRIN IRON, ferrous lactate, the ferrous bisglycinate chelate.
Preferably, said organic iron is made up of polyferose 8～20 mass parts, PORPHYRIN IRON 5～20 mass parts, ferrous lactate 12～28 mass parts, ferrous bisglycinate chelate 8～30 mass parts.
Preferably, said synergist is at least a in glutathione, nicotinamide-adenine dinucleotide phosphate, biological flavone, nucleotides, the cobalamin.
Preferably, said synergist is by glutathione 2～5 mass parts, nicotinamide-adenine dinucleotide phosphate 2～6 mass parts, and biological flavone 1.6～5 mass parts, nucleotides 1.6～5 mass parts, cobalamin 1～3 mass parts is formed.
Preferably, this benefit Fe composition also contains the white carbon of 3～18 mass parts.
The preparation method of above-mentioned benefit Fe composition comprises the steps:
1) protoporphyrin, synergist and a certain amount of white carbon are mixed, get mixture 1;
2) organic iron and remaining white carbon are mixed, get mixture 2;
3) mixture 1 is mixed with mixture 2, must mend Fe composition.
Preferably, the step 1) white carbon is 2～4 mass parts.
The invention has the beneficial effects as follows:
Benefit Fe composition of the present invention is applicable to domestic animal, poultry, and being particularly useful for the pig is main domestic animal, poultry, and benefit Fe composition of the present invention quickens red blood cell propagation, and it is synthetic to have improved hemoglobin, and the hematopoiesis effect is significantly increased.The present invention adopts the source of iron of multiple different organic iron as hematopoiesis, makes source of iron obtain body and farthest absorbs; The ferrous reducing condition of protection hemoglobin keeps the red blood cell optimum Working; Protection ferrous iron not oxidized one-tenth trivalent and losing efficacy under the disassociation state guarantees the ferrous iron maximize absorption.
Description of drawings
Fig. 1 is piglet one figure that mends the Fe composition group;
Fig. 2 is piglet two figure that mend the Fe composition group;
Fig. 3 be control group piglet one figure;
Fig. 4 be control group piglet two figure;
Fig. 5 mends porkling one figure that the Fe composition group is produced;
Fig. 6 mends porkling two figure that the Fe composition group is produced;
Fig. 7 mends porkling three figure that the Fe composition group is produced;
Fig. 8 mends porkling one figure that control group is produced;
Fig. 9 mends porkling two figure that control group is produced.
The specific embodiment
A kind of benefit Fe composition contains the component of following mass parts: 64～75 parts of organic iron, 2～4 parts of protoporphyrins, 15～18 parts of synergist.
Preferably, said organic iron is at least a in polyferose, PORPHYRIN IRON, ferrous lactate, the ferrous bisglycinate chelate.
Further preferred, said organic iron is made up of polyferose 8～20 mass parts, PORPHYRIN IRON 5～20 mass parts, ferrous lactate 12～28 mass parts, ferrous bisglycinate chelate 8～30 mass parts.Adopt the source of iron of multiple different organic iron as hematopoiesis, purpose is to make source of iron obtain body farthest to absorb, and hematopoiesis core material protoporphyrin also is provided, for hemopoietic system provides material base.
Preferably, said synergist is at least a in glutathione, nicotinamide-adenine dinucleotide phosphate (NADPH coenzyme), biological flavone, nucleotides, the cobalamin.
Further preferred, said synergist is by glutathione 2～5 mass parts, nicotinamide-adenine dinucleotide phosphate (NADPH coenzyme) 2～6 mass parts, and biological flavone 1.6～5 mass parts, nucleotides 1.6～5 mass parts, cobalamin 1～3 mass parts is formed.The synergistic component of this synergist combination the interpolation simultaneously different-effect farthest reaches the hematopoiesis effect through a plurality of approach.
The present invention has strengthened and cell division propagation, synthetic, synthetic relevant nutrition such as B12, the nucleotides etc. of albumen of DNA, and the hematopoiesis effect is had remarkable effect.The present invention has solved the unfavorable difficult problem of prior art system hematopoiesis effect from the hematopoiesis source.
The appearance of the methemoglobinemia on the physianthropy is oxidized to ferric iron as long as erythrocytic ferrous iron surpasses 1%, and anoxic symptoms such as cyanosis will appear in people's lip.And red blood cell mainly rely on NADPH coenzyme, cytochrome peroxidase and glutathione peroxidase come common ferrous reducing condition of safeguarding.Synergy component among the present invention has been strengthened NADPH coenzyme and glutathione especially, guarantees erythrocytic efficient.Ferrous iron is oxidized to the ferric iron that is difficult for absorption easily under aqueous solution dissociated state.The present invention has strengthened biological flavone and glutathione, protects the validity of iron to greatest extent.
Preferably, this benefit Fe composition also contains the white carbon of 3～18 mass parts.
The preparation method of above-mentioned benefit Fe composition comprises the steps:
1) white carbon with protoporphyrin, synergist and 2～4 mass parts mixes, and gets mixture 1;
2) organic iron and remaining white carbon are mixed, get mixture 2;
3) mixture 1 and mixture 2 are mixed, must mend Fe composition.
Embodiment below in conjunction with concrete is further described the present invention, but does not limit to so.
Embodiment 1
A kind of benefit Fe composition contains the component of following mass parts: 2 parts of protoporphyrins, 14 parts of white carbons, 16 parts of polyferoses, 5 parts of PORPHYRIN IRON, 28 parts of ferrous lactates, 20 parts of ferrous bisglycinate chelates, 2 parts of glutathione, 3 parts of NADPH coenzyme, 5 parts of biological flavones, 3 parts in nucleotides, 2 parts of cobalamins;
The preparation method of above-mentioned benefit Fe composition comprises the steps:
1) white carbon with protoporphyrin, glutathione, NADPH coenzyme, biological flavone, nucleotides, cobalamin and 4 mass parts mixes, and gets mixture 1;
2) polyferose, PORPHYRIN IRON, ferrous lactate, ferrous bisglycinate chelate and remaining white carbon are mixed, get mixture 2;
3) mixture 1 and mixture 2 are mixed, must mend Fe composition.
Embodiment 2
A kind of benefit Fe composition contains the component of following mass parts: 2.5 parts of protoporphyrins, 18 parts of white carbons, 8 parts of polyferoses, 20 parts of PORPHYRIN IRON, 20 parts of ferrous lactates, 16 parts of ferrous bisglycinate chelates, 2.6 parts of glutathione, 5.3 parts of NADPH coenzyme, 1.6 parts of biological flavones, 5 parts in nucleotides, 1 part of cobalamin;
The preparation method of above-mentioned benefit Fe composition comprises the steps:
1) white carbon with protoporphyrin, glutathione, NADPH coenzyme, biological flavone, nucleotides, cobalamin and 4 mass parts mixes, and gets mixture 1;
2) polyferose, PORPHYRIN IRON, ferrous lactate, ferrous bisglycinate chelate and remaining white carbon are mixed, get mixture 2;
3) mixture 1 and mixture 2 are mixed, must mend Fe composition.
Embodiment 3
A kind of benefit Fe composition contains the component of following mass parts: 4 parts of protoporphyrins, 3 parts of white carbons, 17 parts of polyferoses, 16 parts of PORPHYRIN IRON, 12 parts of ferrous lactates, 30 parts of ferrous bisglycinate chelates, 5 parts of glutathione, 2 parts of NADPH coenzyme, 4 parts of biological flavones, 4 parts in nucleotides, 3 parts of cobalamins;
The preparation method of above-mentioned benefit Fe composition comprises the steps:
1) white carbon with protoporphyrin, glutathione, NADPH coenzyme, biological flavone, nucleotides, cobalamin and 2 mass parts mixes, and gets mixture 1;
2) polyferose, PORPHYRIN IRON, ferrous lactate, ferrous bisglycinate chelate and remaining white carbon are mixed, get mixture 2;
3) mixture 1 and mixture 2 are mixed, must mend Fe composition.
Embodiment 4
A kind of benefit Fe composition contains the component of following mass parts: 2.5 parts of protoporphyrins, 13.5 parts of white carbons, 20 parts of polyferoses, 12 parts of PORPHYRIN IRON, 27 parts of ferrous lactates, 8 parts of ferrous bisglycinate chelates, 3.4 parts of glutathione, 6 parts of NADPH coenzyme, 3.5 parts of biological flavones, 1.6 parts in nucleotides, 2.5 parts of cobalamins;
The preparation method of above-mentioned benefit Fe composition comprises the steps:
1) white carbon with protoporphyrin, glutathione, NADPH coenzyme, biological flavone, nucleotides, cobalamin and 3 mass parts mixes, and gets mixture 1;
2) polyferose, PORPHYRIN IRON, ferrous lactate, ferrous bisglycinate chelate and remaining white carbon are mixed, get mixture 2;
3) mixture 1 and mixture 2 are mixed, must mend Fe composition.
Embodiment 5
A kind of benefit Fe composition contains the component of following mass parts: 2 parts of protoporphyrins, 16 parts of white carbons, 64 parts of polyferoses, 5 parts of NADPH coenzyme, 5 parts of biological flavones, 8 parts in nucleotides;
The preparation method of above-mentioned benefit Fe composition comprises the steps:
1) white carbon with protoporphyrin, NADPH coenzyme, biological flavone, nucleotides and 3 mass parts mixes, and gets mixture 1;
2) polyferose and remaining white carbon are mixed, get mixture 2;
3) mixture 1 and mixture 2 are mixed, must mend Fe composition.
Embodiment 6
A kind of benefit Fe composition contains the component of following mass parts: 3 parts of protoporphyrins, 13 parts of white carbons, 17 parts of PORPHYRIN IRON, 26 parts of ferrous lactates, 26 parts of ferrous bisglycinate chelates, 15 parts of biological flavones;
The preparation method of above-mentioned benefit Fe composition comprises the steps:
1) white carbon with protoporphyrin, glutathione, NADPH coenzyme, biological flavone, nucleotides, cobalamin and 2 mass parts mixes, and gets mixture 1;
2) polyferose, PORPHYRIN IRON, ferrous lactate, ferrous bisglycinate chelate and remaining white carbon are mixed, get mixture 2;
3) mixture 1 and mixture 2 are mixed, must mend Fe composition.
Benefit Fe composition of the present invention is applicable to the pig to be main domestic animal, poultry, and its usage is: benefit Fe composition of the present invention is made an addition in the complete feed of livestock or poultry in proportion, and mixing is used for the feed behind the mixing to keep fowls or poultry.The consumption that benefit Fe composition of the present invention is applied to different domestic animals, poultry is seen table 1.
Draw through practice, the effect that benefit Fe composition of the present invention is used for different domestic animals, poultry is following:
1) is used for farrowing sow, can improves the fetus blood supply, improve survival rate, litter weight and litter size;
2) be used for milking sow, can improve heavy tire phase blood supply, promote the birth litter weight and improve the milk quality;
3) be used for piglet≤30kg, can improve the long speed of newborn piglet, resistance, the ruddy gloss of the colour of skin; Long speed, resistance and yellowish pink for the pig of body weight>=30kg have important value; Sell piglet or boar and to use benefit Fe composition of the present invention in preceding 1 month, can make that the pig colour of skin is ruddy, health has vigor;
4) growing too fast kind or season, can solve yellowish pink pale dripping and yellow fat problem;
5), can improve the eggshell color for poultry; Improve and plant a chicken reproductive performance, through the hematopoiesis oxygen supply, increase the tolerance (plateau climate, airtight hen house) to oxygen, appearance, feedstuff-meat ratio reduction and the weightening finish of minimizing fast big chicken ascites symptoms in winter, make the cockscomb of fryer, kind chicken ruddy, the color and luster of feather is beautiful.
The present invention mends the influence of Fe composition to piglet production performance and fur outward appearance:
Flat certain breeding pig farm is opened in the test place in Guangdong, test divides two groups, every group 4 hurdle; 18 piglets in every hurdle, piglet weight is 14～30kg, one group for mending the Fe composition group; The benefit Fe composition group of embodiment 1 is (positive famous in the complete feed that the ratio of 200g/ t feed makes an addition to piglet; Trade name " pig Triratna ") in, mixes, feed piglet; Two groups is control group, and ferrous bisglycinate chelate is made an addition in the complete feed (positive famous, trade name " pig Triratna ") of piglet in the ratio of 350g/t feed, mixes, and feeds piglet; Test period: 2011.5.18～2011.6.14 all feeds piglet by the usage and the consumption of complete feed for two groups, and two groups nursing time and consumption all are consistent.
Off-test, the average long speed of two groups of piglets, i.e. average daily gain is seen table 2 with average feedstuff-meat ratio statistics.Visible by table, mend the Fe composition group, the daily gain of piglet increases, feedstuff-meat ratio reduces, so use benefit Fe composition of the present invention, the daily gain of piglet, the price of deed be improved significantly, animal health.
After mending the off-test of Fe composition group, the photo of piglet is seen Fig. 1 and Fig. 2, can know that by Fig. 1 and Fig. 2 the piglet colour of skin is ruddy, the skin good luster; Hair is short, hair is bright, and resistance is strong, blood foot, red blood cell foot, health; Body is plentiful, and the pig of this group sells the lover, and premunition is strong, and adaptive faculty is strong.After the control group off-test, the photo of piglet is seen Fig. 3 and Fig. 4, can know with Fig. 1 and Fig. 2 contrast, and the piglet staple length, skin is matt, and red blood cell is not enough, and the resistance of this group pig is general, compares with mending the Fe composition group, and is liable to illness.It is thus clear that benefit Fe composition of the present invention can be through strengthening hematopoietic function, the healthy looking that reaches pig is ruddy, and health has vigor.
The present invention mends Fe composition and is used for the influence of farrowing sow to newborn piglet production performance and fur outward appearance:
The test place is in Wuhan, Hubei, and EmilZatopek (Topigs) is the original seed pig farm for generations, and test divides two groups; Every group of 12 farrowing sows, have a try the stage of testing: one group for mending the Fe composition group to childbirth in antenatal 1 month; The benefit Fe composition group of embodiment 1 is (positive famous in the complete feed that the ratio of 400g/ t feed makes an addition to farrowing sow; 567 farrowing sows material) in, mixes, feed farrowing sow; Two groups is control group, and ferrous bisglycinate chelate is made an addition in the complete feed (positive famous, 567 farrowing sows material) of farrowing sow in the ratio of 400g/t feed, mixes, and feeds farrowing sow; All feed farrowing sow by the usage and the consumption of complete feed for two groups, two groups nursing time and consumption all are consistent.
From producing previous month the nursing to childbirth, two groups of farrowing sows result of the test see table 3.Visible by table, mend the Fe composition group, litter weight increases the 3.38kg/ nest, and the porkling of product is obviously ruddy glossy, energetic.
Mend the Fe composition group, the photo of the porkling of production is seen Fig. 5, Fig. 6 and Fig. 7, can know that by figure the skin of porkling is ruddy glossy, and is energetic, and hair is short, and porkling sell the lover, premunition is strong, adaptive faculty is strong.The photo of the porkling of control group production is seen Fig. 8 and Fig. 9, can know that by figure the hair of porkling is long, and the porkling skin of not mending the Fe composition group is ruddy glossy.This test main purpose is to investigate the influence of hematopoiesis to the fur outward appearance; Benefit Fe composition of the present invention can see through placental barrier fully; Thereby influence fetus and parent hematopoiesis, influence the supply of oxygen and nutriment, survival rate, litter size, litter weight, the outward appearance of fetus had important function.Newborn piglet is obviously healthy ruddy and glossy, energetic, is the sufficient embodiment of hematopoiesis.
The present invention mends Fe composition to kind of the influence of chicken reproductive performance:
Experimental animal: the Luo Man of 379 ages in days kind of chicken 15000 plumages of laying eggs, to assign at random in 3 test group, each test group repeats 5 times, repeats with 1000 plumage chickens at every turn.Raised in advance 10 days, and tested, totally 74 days (379 ages in days～453 ages in days) in 2010.6.19～2010.8.31 end of day.
Three test group are respectively: 1) control group: do not add and mend Fe composition in Luo Man lays eggs the complete feed (positive famous, 324 kinds of chickens material) of kind of chicken; 2) low dose group: the benefit Fe composition group of embodiment 1 is made an addition to Luo Man in the ratio of 150g/ t feed lay eggs in the complete feed (positive famous, 324 kinds of chickens material) of kind of chicken, mix, feed Luo Man kind of the chicken of laying eggs; 3) high dose group: the benefit Fe composition group of embodiment 1 is made an addition to Luo Man in the ratio of 200g/ t feed lay eggs in the complete feed (positive famous, 324 kinds of chickens material) of kind of chicken, mix, feed Luo Man kind of the chicken of laying eggs.All feed Luo Man kind of the chicken of laying eggs by the usage of complete feed and consumption for two groups, two groups nursing time and consumption all are consistent.
Mend Fe composition kind of the result of the test of chicken reproductive performance influence is seen table 4; Can know by table 4; The immunity of hematopoiesis enhancing body thereby can reduce chicken crowd's the death rate; Through hematopoiesis enough oxygen of body and nutriment are provided, significantly improve egg size, laying rate, improve kind of an egg qualification rate, rate of fertilization and strong young rate.
Claims (8)
1. mend Fe composition for one kind, it contains the component of following mass parts: 64～75 parts of organic iron, 2～4 parts of protoporphyrins, 15～18 parts of synergist.
2. benefit Fe composition according to claim 1 is characterized in that: said organic iron is at least a in polyferose, PORPHYRIN IRON, ferrous lactate, the ferrous bisglycinate chelate.
3. benefit Fe composition according to claim 2 is characterized in that: said organic iron is made up of polyferose 8～20 mass parts, PORPHYRIN IRON 5～20 mass parts, ferrous lactate 12～28 mass parts, ferrous bisglycinate chelate 8～30 mass parts.
4. benefit Fe composition according to claim 1 is characterized in that: said synergist is at least a in glutathione, nicotinamide-adenine dinucleotide phosphate, biological flavone, nucleotides, the cobalamin.
5. benefit Fe composition according to claim 4; It is characterized in that: said synergist is by glutathione 2～5 mass parts, nicotinamide-adenine dinucleotide phosphate 2～6 mass parts, biological flavone 1.6～5 mass parts; Nucleotides 1.6～5 mass parts, cobalamin 1～3 mass parts is formed.
6. according to each described benefit Fe composition of claim 1～5, it is characterized in that: this benefit Fe composition also contains the white carbon of 3～18 mass parts.
7. the preparation method of benefit Fe composition as claimed in claim 6 comprises the steps:
1) protoporphyrin, synergist and a certain amount of white carbon are mixed, get mixture 1;
2) organic iron and remaining white carbon are mixed, get mixture 2;
3) mixture 1 and mixture 2 are mixed, must mend Fe composition.
8. the preparation method of benefit Fe composition according to claim 7 is characterized in that: the step 1) white carbon is 2～4 mass parts.
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| CN105028314A (en) * | 2015-07-06 | 2015-11-11 | 广州驱动力饲料有限公司 | Iron supplementing method for piglets |
| CN110089624A (en) * | 2019-05-21 | 2019-08-06 | 中国科学院亚热带农业生态研究所 | Piglet by Oral iron supplementary and preparation method thereof |
| CN111298099A (en) * | 2018-11-27 | 2020-06-19 | 湖南现代资源生物科技有限公司 | Iron-supplementing composition and preparation method and application thereof |
| CN115624112A (en) * | 2022-11-02 | 2023-01-20 | 广东驱动力生物科技集团股份有限公司 | Feed additive for reducing health cost of broiler chickens and preparation method thereof |
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