CN102512596A - Traditional Chinese medicine for treating allergic purpura - Google Patents

Traditional Chinese medicine for treating allergic purpura Download PDF

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Publication number
CN102512596A
CN102512596A CN2011104489691A CN201110448969A CN102512596A CN 102512596 A CN102512596 A CN 102512596A CN 2011104489691 A CN2011104489691 A CN 2011104489691A CN 201110448969 A CN201110448969 A CN 201110448969A CN 102512596 A CN102512596 A CN 102512596A
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China
Prior art keywords
chinese medicine
traditional chinese
radix
allergic purpura
raw material
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CN2011104489691A
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龙善煜
马定友
杜翔
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YINGSHAN LEIJIADIAN INSTITUTE OF HEALTH
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YINGSHAN LEIJIADIAN INSTITUTE OF HEALTH
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Priority to CN2011104489691A priority Critical patent/CN102512596A/en
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Abstract

The invention discloses a traditional Chinese medicine for treating allergic purpura, which is prepared from 17 kinds of medicinal materials: jasmine, rheum officinale, radix scutellariae, radix scrophulariae, Chinese angelica, radix rehmanniae, cortex moutan, peach kernels, red paeony root, colla corii asini, cacumen biotae, bletilla striata, folium isatidis, pollen typhae, cimicifugae foetidae, cogongrass rhizome and liquorice. The traditional Chinese medicine has effects of clearing heat, removing toxicity, cooling blood and hemostasis, eliminating heat, removing stasis, diuresis and dispersing swelling and can be treat various allergic purpura. The traditional Chinese medicine has definite curative effects, recurrence is not easy to occur after recovery, no toxic and side effects exist, and the safety is good.

Description

A kind of Chinese medicine that is used to treat anaphylactoid purpura
Technical field:
The present invention relates to a kind of Chinese medicine, specifically is a kind of Chinese medicine that is used to treat anaphylactoid purpura.
Background technology:
Anaphylactoid purpura is claimed schonlein-Henoch purpura again; It is a kind of comparatively common a kind of blood capillary allergy hemorrhage; The category that belongs to the traditional Chinese medical science " hematohidrosis "; Clinical mainly with ecchymosis and mucosal bleeding, normal with lumbago, have blood in stool, the pathological changes of arthralgia or kidney etc., serious threat to life is healthy.
No matter be the doctor trained in Western medicine or the traditional Chinese medical science both at home and abroad at present, not ideal to the treatment effect of anaphylactoid purpura, Western medicine also has certain toxic and side effects, even other organ of infringement human body, and the medicine cost is higher.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine that is used to treat anaphylactoid purpura.
The present invention realizes through following technical scheme:
A kind of Chinese medicine that is used to treat anaphylactoid purpura, by the following weight proportioning raw material process:
Figure BSA00000646454300011
Preferred raw material weight proportioning is:
Figure BSA00000646454300012
Figure BSA00000646454300021
The optimum material weight proportion is:
Figure BSA00000646454300022
The present invention treats the Chinese medicine of anaphylactoid purpura, except above-mentioned raw materials, can also comprise adjuvant.Said adjuvant can be one or more combination of conventional adjuvant in these pharmaceutical preparatioies such as sucrose, starch, dextrin, magnesium stearate, sorbitol, mannitol, microcrystalline Cellulose, micropowder silica gel, carboxymethyl starch sodium, carboxymethyl cellulose, water, specifically selects any or which is planted adjuvant and should confirm according to the required dosage form of processing.Because selecting suitable adjuvant according to the dosage form needs is the technology that those of ordinary skills can both grasp, therefore will prepare the required adjuvant of medicine of the present invention and bring in the scope of patent requirement protection.
Said Chinese medicine can be any dosage form that is suitable for clinical use, for example: decoction, tablet, powder, granule, capsule, pill, unguentum, mixture, syrup etc.Said raw material is processed appropriate pharmaceutical dosage forms after can pulverizing; Also can after extracting, concentrating, process appropriate pharmaceutical dosage forms again; For example can raw material all be pulverized the back suitable adjuvant of adding and process tablet, powder, granule, capsule, pill; Process decoction or add suitable adjuvant again after perhaps raw material all being extracted and process tablet, granule, capsule, unguentum, mixture, syrup, can also raw material partly be pulverized, add suitable adjuvant again after the extracting section and process tablet, granule, capsule, pill, unguentum.Method for distilling can adopt conventional water boiling and extraction or alcohol reflux in the Chinese medicine preparation.Said method is that the routine that those of ordinary skills grasp according to the character of raw material properties and contained active ingredient is selected.
A kind of method for preparing provided by the invention may further comprise the steps:
1, raw material pre-treatment: get Cacumen Platycladi, fry with high heat to surperficial pitchy, inner coke yellow, the spray little of clean water is extinguished Mars, takes out, and dries; Get Pollen Typhae, fry with high heat to sepia, the spray little of clean water is extinguished Mars, takes out, and dries; All the other medical materials are processed decoction pieces.
2, Colla Corii Asini molten: Colla Corii Asini is put into hot water dissolve, subsequent use.
3, decoct: get 13 flavor medical materials except that Colla Corii Asini, Radix Et Rhizoma Rhei, add suitable quantity of water and decocted 0.5-3 hour.
4, under behind the Radix Et Rhizoma Rhei: when step 3 decocts 5~10 minutes before ceasing fire, add Radix Et Rhizoma Rhei.
5, filter, mix: the medical filtration after will decocting, the Colla Corii Asini mix homogeneously of adding step 2 molten.
Folium Isatidis, Rhizoma Cimicifugae, Radix Scutellariae, Radix Glycyrrhizae heat-clearing and toxic substances removing in the Chinese medicine of the present invention, dispelling wind for relieving itching, speckle dispelling; Fructus Gardeniae, the Radix Rehmanniae, Radix Paeoniae Rubra, Radix Scrophulariae, the hemostasis of Cortex Moutan clearing away heat and cooling blood; Colla Corii Asini can promote hemagglutinative function, and Radix Angelicae Sinensis has the merit of growing intestinal relieving constipation diuresis again, and two medicines have share to be mended and not puckery wonderful; Platycladi Cacumen carbonisatum, Pollen Tyjphae (parched), Pseudobulbus Bletillae (Rhizoma Bletillae) hemostasis, the Pseudobulbus Bletillae (Rhizoma Bletillae) and the effect of detumescence is arranged; Rhizoma Imperatae is joined the power that Radix Scutellariae has clearing away heat and cooling blood hemostasis diuresis again, helps with Radix Et Rhizoma Rhei, Semen Persicae with the blood stasis dispelling that expels the heat-evil.
Chinese medicine of the present invention has heat-clearing and toxic substances removing, cooling blood for hemostasis, the effect of the blood stasis dispelling that expels the heat-evil, diuresis, detumescence, can be used for the treatment of various anaphylactoid purpura.Chinese medicine determined curative effect of the present invention, more the back is difficult for recurrence, and has no side effect, and safety is good.
Continue to provide the observation of curative effect data to be used to further specify beneficial effect of the present invention below:
1, diagnostic criteria:
Figure BSA00000646454300031
Figure BSA00000646454300041
2, Therapeutic Method:
Typing Case load Produce effects Effectively Unsatisfactory curative effect
The injury of blood collaterals by heat type 24 16 8 0
The obstruction of collaterals by blood stasis type 20 13 6 1
The Qi and blood deficiency type 16 3 10 3
Add up to 60 32 24 4
3, efficacy assessment standard
Work out as follows with reference to State Administration of Traditional Chinese Medicine (95) (diagnostic criteria of traditional Chinese medical science disease curative effect):
Produce effects: the syndrome score descends more than 60%.
Effectively: the syndrome score descends 30%~60%.
Invalid: syndrome score decline less than 30%.
4, safety evaluatio standard
1 grade: safety, there is not any untoward reaction.
2 grades: compare safety,, need not do any processing and can continue administration if any untoward reaction.
3 grades: safety issue is arranged, moderate untoward reaction is arranged, can continue administration after processing.
4 grades: because of test is ended in untoward reaction.
Result of the test: the clinical observation result of directly using treatment by Chinese herbs of the present invention: observe 60 cases altogether, produce effects 32 examples (53.3%) wherein, effective 24 examples (40.0%), total effective rate is 93.3%.(total effective rate=obvious effective rate+effective percentage).Do not find tangible untoward reaction.
The specific embodiment
Embodiment 1
A kind of Chinese medicine that is used to treat anaphylactoid purpura, by the following weight proportioning raw material process:
Figure BSA00000646454300051
Method for preparing is:
1, raw material pre-treatment: get Cacumen Platycladi, fry with high heat to surperficial pitchy, inner coke yellow, the spray little of clean water is extinguished Mars, takes out, and dries; Get Pollen Typhae, fry with high heat to sepia, the spray little of clean water is extinguished Mars, takes out, and dries; All the other medical materials are processed decoction pieces.
2, Colla Corii Asini molten: Colla Corii Asini is put into hot water dissolve, subsequent use.
3, decoct: get 13 flavor medical materials except that Colla Corii Asini, Radix Et Rhizoma Rhei, add suitable quantity of water and decocted 0.5-3 hour.
4, under behind the Radix Et Rhizoma Rhei: when step 3 decocts 5~10 minutes before ceasing fire, add Radix Et Rhizoma Rhei.
5, filter, mix: the medical filtration after will decocting, the Colla Corii Asini mix homogeneously of adding step 2 molten.
Chinese medicine of the present invention has heat-clearing and toxic substances removing, cooling blood for hemostasis, the effect of the blood stasis dispelling that expels the heat-evil, diuresis, detumescence, can be used for the treatment of various anaphylactoid purpura.Mainly be to the food foreign protein as: fish, shrimp, egg, Lac Bovis seu Bubali etc. are irritated, suck pollen and sting, bacterial infection, the caused indication of part drug allergy sequela.
The instructions of taking of Chinese medicine of the present invention is: oral, potion on the one divides and takes for early, middle and late three times.
Embodiment 2
A kind of Chinese medicine that is used to treat anaphylactoid purpura, by the following weight proportioning raw material process:
Figure BSA00000646454300061
Method for preparing is: above-mentioned pulverizing medicinal materials is become fine powder, cross 100 mesh sieves, add appropriate amount of starch, mix homogeneously is processed powder.
Embodiment 3
A kind of Chinese medicine that is used to treat anaphylactoid purpura, by the following weight proportioning raw material process:
Figure BSA00000646454300062
Method for preparing is: with above-mentioned medical material decocte with water 3 times, each 1 hour, collecting decoction filtered, and filtrating is condensed into clear paste, adds an amount of Icing Sugar and processes granule.
Embodiment 4
A kind of Chinese medicine that is used to treat anaphylactoid purpura, by the following weight proportioning raw material process:
Figure BSA00000646454300063
Method for preparing is: get Fructus Gardeniae, Radix Et Rhizoma Rhei, Radix Scrophulariae, Rhizoma Cimicifugae with 60% alcohol reflux 2 times, and each 2 hours, filter, merging filtrate also is condensed into clear paste, and is subsequent use; Get Radix Scutellariae, Radix Angelicae Sinensis, the Radix Rehmanniae, Cortex Moutan, Semen Persicae, Radix Paeoniae Rubra, Cacumen Platycladi, the Pseudobulbus Bletillae (Rhizoma Bletillae), Folium Isatidis, Pollen Typhae, Rhizoma Imperatae, Radix Glycyrrhizae decocte with water 2 times, each 2 hours, merging filtrate also is condensed into clear paste, and was subsequent use; Colla Corii Asini is ground into fine powder, with an amount of Icing Sugar mix homogeneously, adds above-mentioned two kinds of clear paste, stir, granulate, add an amount of magnesium stearate, tabletting is processed tablet.
Embodiment 5
A kind of Chinese medicine that is used to treat anaphylactoid purpura, by the following weight proportioning raw material process:
Method for preparing is: gets Colla Corii Asini, puts into suitable quantity of water and dissolve, and subsequent use; Get all the other ten four Chinese medicine materials, decocte with water 2 times, each 2 hours, collecting decoction was concentrated into relative density and is 1.10 clear paste, put cold back and added ethanol and make that to contain the alcohol amount be 50%, left standstill to get supernatant after 24 hours and reclaim ethanol, added an amount of simple syrup and processed syrup.

Claims (3)

1. Chinese medicine that is used to treat anaphylactoid purpura is characterized in that said Chinese medicine processed by the following weight proportion raw material:
Figure FSA00000646454200011
2. the Chinese medicine that is used to treat anaphylactoid purpura as claimed in claim 1 is characterized in that said Chinese medicine processed by the following weight proportion raw material:
Figure FSA00000646454200012
3. according to claim 1 or claim 2 the Chinese medicine that is used to treat anaphylactoid purpura, it is characterized in that said Chinese medicine by the following weight proportioning raw material process:
Figure FSA00000646454200013
CN2011104489691A 2011-12-28 2011-12-28 Traditional Chinese medicine for treating allergic purpura Pending CN102512596A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105521191A (en) * 2015-09-17 2016-04-27 张名静 Traditional Chinese medicine for treating allergic purpura
CN114569673A (en) * 2022-04-24 2022-06-03 李宗霞 Traditional Chinese medicine preparation for treating skin scald scars

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1385213A (en) * 2002-06-14 2002-12-18 赵金凯 Decolouring technology for compound Chinese herbal medicine
CN101658643A (en) * 2009-09-15 2010-03-03 刘锋 Medicament for treating allergic purpura

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1385213A (en) * 2002-06-14 2002-12-18 赵金凯 Decolouring technology for compound Chinese herbal medicine
CN101658643A (en) * 2009-09-15 2010-03-03 刘锋 Medicament for treating allergic purpura

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
龙善煜: "紫斑证治验", 《湖北中医杂志》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105521191A (en) * 2015-09-17 2016-04-27 张名静 Traditional Chinese medicine for treating allergic purpura
CN114569673A (en) * 2022-04-24 2022-06-03 李宗霞 Traditional Chinese medicine preparation for treating skin scald scars
CN114569673B (en) * 2022-04-24 2024-04-23 李宗霞 Traditional Chinese medicine preparation for treating skin scald and scar

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Application publication date: 20120627