CN102511515A - Spray for ICU (Intensive Care Unit) sterilization - Google Patents
Spray for ICU (Intensive Care Unit) sterilization Download PDFInfo
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- CN102511515A CN102511515A CN2012100099910A CN201210009991A CN102511515A CN 102511515 A CN102511515 A CN 102511515A CN 2012100099910 A CN2012100099910 A CN 2012100099910A CN 201210009991 A CN201210009991 A CN 201210009991A CN 102511515 A CN102511515 A CN 102511515A
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Abstract
The invention relates to a spray for ICU (Intensive Care Unit) sterilization. The spray is prepared from the following substances in weight ratio: 3-5 parts of honeysuckle, 5-15 parts of fructus cnidii, 1-5 parts of plantain herb, 4-8 parts of rhizoma atractylodis, 1-5 parts of schizonepeta, 3-7 parts of root of subprostrate sophora, 5-11 parts of herba violae, 3-5 parts of tuber of stemona and a pharmaceutically acceptable carrier. The spray for ICU sterilization has a simple and clear composition and an obvious disinfection effect; and the spray is used in a spray formulation, so that a disinfection effect can be brought into full play.
Description
Technical field
The present invention relates to field of medicaments, relate in particular to a kind of spray of the ICU of being used for sterilization.
Background technology
Intensive care unit (ICU) is the ward of accepting seriously ill patient for medical treatment, and wherein most of seriously ill patient is ill comparatively serious, and health is relatively weaker, and resistance is relatively poor, must sterilize effectively for the ward.And because mostly the patient is seriously ill patient, handicapped, the patient is moved less.
Find that through years of researches the main pathogenic bacteria in intensive care unit are staphylococcus aureus (Staphylococcus aureus) and Candida albicans (Candida albicans), therefore, the emphasis of research is concentrated these two kinds of bacteriums.
Summary of the invention
The spray that the purpose of this invention is to provide a kind of ICU of being used for sterilization.
In order to realize the object of the invention; The present invention provides a kind of spray of the ICU of being used for sterilization, and it is to be processed by following materials by weight: honeysuckle 3-5 part, frutus cnidii 5-15 part, Asiatic plantain 1-5 part, rhizoma atractylodis 4-8 part, schizonepeta 1-5 part, subprostrate sophora 3-7 part, Chinese violet 5-11 part, tuber of stemona 3-5 part and pharmaceutically acceptable carrier.
Preferably, the spray of the described ICU of being used for sterilization is to be processed by following materials by weight: 4 parts of honeysuckles, 10 parts of frutus cnidiis, 2 parts of Asiatic plantains, 5 parts of rhizoma atractylodis, 2 parts of schizonepeta, 4 parts of subprostrate sophoras, 7 parts of Chinese violets, 4 parts of the tubers of stemona and pharmaceutically acceptable carrier.
Spray is the novel form of developing in the drug research, and wherein pharmaceutically acceptable carrier is meant the conventional various carriers that use when carrying out the spray preparation, and this is that those skilled in the art easily recognize.For example, pharmaceutically acceptable carrier includes but not limited to: propellant, aromatic, antioxidant, stabilizing agent, pharmaceutically acceptable solvent, sorbefacient, pharmaceutically acceptable cosolvent or the like.The consumption of said pharmaceutically acceptable carrier can be confirmed through conventional method by those skilled in the art.
The spray composition that is used for ICU sterilization of the present invention is simply clear and definite, and Disinfection Effect is obvious, and adopts the spray formulation to use, and during use, only needs medical personnel to walk about to spray get final product, need not mobile patient and can bring into play Disinfection Effect better.
Embodiment
Below description through embodiment the present invention is described further; But this is not to be limitation of the present invention; Those skilled in the art are according to basic thought of the present invention; Can make various modifications or improvement, but only otherwise break away from basic thought of the present invention, all within scope of the present invention.
Embodiment 1: the preparation of spray of the present invention
Take by weighing 700 milliliters in honeysuckle 40 gram, frutus cnidii 100 grams, Asiatic plantain 20 grams, rhizoma atractylodis 50 grams, schizonepeta 20 grams, subprostrate sophora 40 grams, Chinese violet 70 grams, the tuber of stemona 40 grams and water, place in the flask of sealing.Heating is 5 hours under 30 ℃ water-bath, filters, and collects filtrating, is concentrated into 300 milliliters.Adding 20 gram Tween-60s, 1 gram peppermint oil and 20 milliliters of propane diols mix, and sterilize, and pour in 100 bottles of sprayers promptly to get.
Experimental example 1: bacteriostatic test
Adopt filter paper method classical in this area to carry out bacteriostatic test, wherein:
1. material
1.1 supply the examination bacterial classification
Staphylococcus aureus (Staphylococcus aureus) ATCC 25923, Candida albicans (Candida albicans) ACTT 12228 is all available from Chinese biological goods calibrating institute.
1.2 culture fluid
Nutrient agar and nutrient broth are available from the prosperous chemical reagent of Dalian treasure Co., Ltd.
1.3 test method
Staphylococcus aureus and Candida albicans are inoculated on the agar plate nutrient solution plane, evenly gather during inoculation.The aseptic circular filter paper sheet of tweezer, the spray of spraying preparation among the embodiment 1 be to complete wetting, is attached on the agar plate nutrient solution plane of inoculated bacteria.Agar plate placed in 37 ℃ the incubator incubation 24 hours.Measure the diameter of antibacterial ring.Measuring 3 times averages.
1.4 result
The average diameter of the antibacterial ring of staphylococcus aureus is 7.63mm, and the average diameter of the antibacterial ring of Candida albicans is 5.91mm, shows that spray of the present invention has tangible fungistatic effect.
Experimental example 2: the bacteriostatic test in the ward
Equal 20m at careat
2Spray among the embodiment 1 100 milliliters of the sprays of preparation in the ward equably.Established 3 sampled points with the sampling of plate sedimentation in 12 hours, 24 hours, 48 hours after sprinkling, and on 1 diagonal, got 3 points, respectively get 1 point, and repeat 10 times at promptly middle 1 point, two end distance wall 1m places.After the sampling, medium put in 35 ℃ of incubators cultivate 48h, observe bacterial clump quantity on the medium, calculate bacterial number, air bacteria containing amount (cfu/m by following formula in highlight
3The average clump count of)=every ware * 50000/ plate open-assembly time * plate area.All bacteriums are all identified by " national clinical examination operational procedure ".After sprinkling 12 hours, 24 hours, 48 hours, bacterial number (cfu/m
3) be respectively 63,107,138, meet and pay attention to the requirement (≤200) of ICU for bacterial number.
Claims (2)
1. a spray that is used for the ICU sterilization is characterized in that it is to be processed by following materials by weight: honeysuckle 3-5 part, frutus cnidii 5-15 part, Asiatic plantain 1-5 part, rhizoma atractylodis 4-8 part, schizonepeta 1-5 part, subprostrate sophora 3-7 part, Chinese violet 5-11 part, tuber of stemona 3-5 part and/or pharmaceutically acceptable carrier.
2. the spray that is used for the ICU sterilization according to claim 1 is characterized in that it is to be processed by following materials by weight: 4 parts of honeysuckles, 10 parts of frutus cnidiis, 2 parts of Asiatic plantains, 5 parts of rhizoma atractylodis, 2 parts of schizonepeta, 4 parts of subprostrate sophoras, 7 parts of Chinese violets, 4 parts of the tubers of stemona and/or pharmaceutically acceptable carrier.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210009991 CN102511515B (en) | 2012-01-13 | 2012-01-13 | Spray for ICU (Intensive Care Unit) sterilization |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210009991 CN102511515B (en) | 2012-01-13 | 2012-01-13 | Spray for ICU (Intensive Care Unit) sterilization |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102511515A true CN102511515A (en) | 2012-06-27 |
| CN102511515B CN102511515B (en) | 2013-09-11 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201210009991 Expired - Fee Related CN102511515B (en) | 2012-01-13 | 2012-01-13 | Spray for ICU (Intensive Care Unit) sterilization |
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| CN (1) | CN102511515B (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103039544A (en) * | 2012-12-31 | 2013-04-17 | 周静 | Agent for disinfection of operating room |
| CN103039543A (en) * | 2012-12-31 | 2013-04-17 | 孔祥红 | Spraying agent for disinfection of intensive care unit |
| CN103749573A (en) * | 2012-12-31 | 2014-04-30 | 周静 | Preparation method of medicament for operating room disinfection |
| CN105165901A (en) * | 2015-08-26 | 2015-12-23 | 新昌县大成生物科技有限公司 | Compound herbicide containing plant extractives |
| CN105994407A (en) * | 2016-07-30 | 2016-10-12 | 李爱花 | Sterilization disinfectant used in intensive care unit and preparation method |
| CN108157406A (en) * | 2017-12-26 | 2018-06-15 | 庞振方 | A kind of operating room thimerosal and preparation method thereof |
| CN108938992A (en) * | 2018-09-28 | 2018-12-07 | 贺云峰 | A kind of operating room special sterilizing thimerosal |
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| CN1289542A (en) * | 1999-09-25 | 2001-04-04 | 铜陵市人民医院 | Air disinfectant and preparing process thereof |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103039544A (en) * | 2012-12-31 | 2013-04-17 | 周静 | Agent for disinfection of operating room |
| CN103039543A (en) * | 2012-12-31 | 2013-04-17 | 孔祥红 | Spraying agent for disinfection of intensive care unit |
| CN103039543B (en) * | 2012-12-31 | 2014-01-29 | 孔祥红 | Spraying agent for disinfection of intensive care unit |
| CN103749573A (en) * | 2012-12-31 | 2014-04-30 | 周静 | Preparation method of medicament for operating room disinfection |
| CN103749573B (en) * | 2012-12-31 | 2015-05-13 | 高群 | Preparation method of medicament for operating room disinfection |
| CN105165901A (en) * | 2015-08-26 | 2015-12-23 | 新昌县大成生物科技有限公司 | Compound herbicide containing plant extractives |
| CN105994407A (en) * | 2016-07-30 | 2016-10-12 | 李爱花 | Sterilization disinfectant used in intensive care unit and preparation method |
| CN108157406A (en) * | 2017-12-26 | 2018-06-15 | 庞振方 | A kind of operating room thimerosal and preparation method thereof |
| CN108938992A (en) * | 2018-09-28 | 2018-12-07 | 贺云峰 | A kind of operating room special sterilizing thimerosal |
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|---|---|
| CN102511515B (en) | 2013-09-11 |
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