CN102613258B - Spray for sterilizing air in operating room - Google Patents

Spray for sterilizing air in operating room Download PDF

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Publication number
CN102613258B
CN102613258B CN 201210064380 CN201210064380A CN102613258B CN 102613258 B CN102613258 B CN 102613258B CN 201210064380 CN201210064380 CN 201210064380 CN 201210064380 A CN201210064380 A CN 201210064380A CN 102613258 B CN102613258 B CN 102613258B
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China
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grams
operating room
spray
root
bark
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Expired - Fee Related
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CN 201210064380
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Chinese (zh)
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CN102613258A (en
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王振华
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Individual
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  • Medicines Containing Plant Substances (AREA)
  • Disinfection, Sterilisation Or Deodorisation Of Air (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention relates to pressurized spray for sterilizing air in an operating room, which comprises the following ingredients and pharmaceutically acceptable carriers: rhizoma atractylodis, radix stemonae, rhizoma coptidis, cortex eucommiae, cassia seeds, eclipta alba, radix stephaniae tetrandrae, root-bark of Chinese wolfberry and thesium chinensis. The pressurized spray for sterilizing the air in the operating room has an obvious effect and is low in cost and suitable for being widely used clinically.

Description

A kind of spray for the operating room air sterilization
Technical field
The present invention relates to field of medicaments, particularly, the present invention relates to a kind of spray for the operating room air sterilization.
Background technology
Operating room is the high-risk section office that nosocomial infection takes place, and one of effective measures of prevention nosocomial infection are exactly to make the operating room air sterilization reach standard-required.If air sterillization is not in place, will directly influence the operation quality, cause the operative incision delayed union, reduce operative incision healing probability, prolonged the length of patient stay simultaneously, increased patient's financial burden and misery.In surgical procedure, because personnel's activity causes airborne particulate loading to increase, reduced air quality; The aerial contaminate particulate that swims deposits sometimes, causes the infection of operative incision, influences surgical result.Therefore, select a kind of efficient, quick, safe sterilization method for use is the target of pursuing always.
Summary of the invention
The purpose of this invention is to provide a kind of spray for the operating room air sterilization.
In order to realize purpose of the present invention, the invention provides a kind of spray for the operating room air sterilization, it is made by following ingredients and pharmaceutically acceptable carrier:
Rhizoma atractylodis 1~10 weight portion tuber of stemona 1~5 weight portion coptis 10~30 weight portions
The bark of eucommia 5~15 weight portion cassia seeds 5~15 weight portion Eclipta prostratas 3~9 weight portions
The root of fangji 5~20 weight portion root barks of Chinese wolf-berry 1~5 weight portion Thesium chinese 1~10 weight portion.
Preferably, the spray for the operating room air sterilization of the present invention is made by following ingredients and pharmaceutically acceptable carrier:
The rhizoma atractylodis 5 weight portion tubers of stemona 3 weight portion coptiss 20 weight portions
The bark of eucommia 10 weight portion cassia seeds 10 weight portion Eclipta prostratas 5 weight portions
The root of fangji 10 weight portion root barks of Chinese wolf-berry 3 weight portion Thesium chineses 5 weight portions.
In this article, carrier, auxiliary material or the excipient of the routine that term " pharmaceutically acceptable carrier " adopts when referring to prepare spray, those skilled in the art can select from the carrier of knowing.
Spray effect for the operating room air sterilization of the present invention is obvious, with low cost, is very suitable for using on a large scale clinically.
Embodiment
The following examples will give further instruction to the present invention, but not thereby limiting the invention.
The preparation of embodiment 1 spray of the present invention
Get rhizoma atractylodis 50 grams, the tuber of stemona 30 grams, the coptis 200 grams, the bark of eucommia 100 grams, cassia seed 100 grams, Eclipta prostrata 50 grams, the root of fangji 100 grams, the root bark of Chinese wolf-berry 30 grams, Thesium chinese 50 grams, place in the flask of sealing, add 400 ml waters.Heating is 3 hours under 70 ℃ water-bath, filters, and collects filtrate.KOH aqueous solution 15g, sucrose 15g, the Tween 80 10g of described filtrate and 1 weight % are mixed, in the sprayer of under aseptic condition, evenly packing into.The sprayer volume is 30ml, and each spray amount is 2ml.
The test example
Select three spatial volume to equate that (area is about 40m 2, high about 5m) operating room as experimental subjects, aspect differences such as the operating room operation is big or small, surgical staff quantity and surgery duration do not have significance, have comparativity (P>0.05).The operating room door and window all seals tightly, and ventilation condition is good, 20~26 ℃ of indoor temperatures, humidity 60%~80%.
Sterilization method: before the operating room sterilization health is thoroughly cleaned up, indoor article is put neatly, does not stack, and uses the spray that makes among the embodiment 1 to spray respectively.Respectively at East, West, South, North, in 5 spray points are set, overhead highly be 1m, each spray point sprays 10ml.
The method of sampling: adopt 9cm diameter ordinary nutrient agar plate exposure method, East, West, South, North, in each spray point place, flat board lid is opened, expose 5min, the plate of will sampling then places cultivates 24h in 37 ℃ of incubators, calculate the average clump count (cfu/m of 5 plates 3).
Sampling time: finish back the 30min unmanned movable and movable 15min sampling of 4 people still respectively at 10min, sterilization before the sterilization.
Count of bacteria method: calculate by the formula in " disinfection technology standard " of country's formulation.Clump count (cfu/m 3)=50000N/AT, N are the clump count (cfu/ plate) of average each plate, and T is that plate is exposed to the airborne time (min), and A is plate area (cm 2).
Effect standard: according to the regulation of " hospital disinfection sanitary standard " and " GB15982-1995 ", bacterial population≤200cfu/m in the operating room air 3, and do not detect staphylococcus aureus.
Collection result is imported PC, use SPSS 10.0 software kits and add up, the result is the preceding 10min bacterial population (cfu/m of sterilization 3) be 842, bacterial population (cfu/m when sterilization finishes back 30min nobody activity still 3) be 53, movable back bacterial population (cfu/m 3) be 143.And all do not detecting staphylococcus aureus after the sterilization He after the activity.Meet relevant regulations.

Claims (1)

1. one kind is used for the spray that operating room air is sterilized, it is characterized in that, it is to make by following method: get rhizoma atractylodis 50 grams, the tuber of stemona 30 grams, the coptis 200 grams, the bark of eucommia 100 grams, cassia seed 100 grams, Eclipta prostrata 50 grams, the root of fangji 100 grams, the root bark of Chinese wolf-berry 30 grams, Thesium chinese 50 grams, place in the flask of sealing, add 400 ml waters, heating is 3 hours under 70 ℃ water-bath, filter, collect filtrate, KOH aqueous solution 15g with described filtrate and 1 weight %, sucrose 15g, Tween 80 10g mixes, evenly pack under aseptic condition in the sprayer, the sprayer volume is 30ml, and each spray amount is 2ml.
CN 201210064380 2012-03-13 2012-03-13 Spray for sterilizing air in operating room Expired - Fee Related CN102613258B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 201210064380 CN102613258B (en) 2012-03-13 2012-03-13 Spray for sterilizing air in operating room

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 201210064380 CN102613258B (en) 2012-03-13 2012-03-13 Spray for sterilizing air in operating room

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CN102613258A CN102613258A (en) 2012-08-01
CN102613258B true CN102613258B (en) 2013-08-21

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Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103039543B (en) * 2012-12-31 2014-01-29 孔祥红 Spraying agent for disinfection of intensive care unit
CN104996472A (en) * 2015-07-16 2015-10-28 王翠平 Bactericide for sterilizing operating room
CN105053057A (en) * 2015-08-04 2015-11-18 别庆收 Bactericide for cardiovascular examination room
CN105284927A (en) * 2015-10-19 2016-02-03 孙华 Operating room disinfectant

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1179965A (en) * 1997-05-15 1998-04-29 李传良 Antiviral anti-influenza spray and its preparing method
CN101990913A (en) * 2009-08-29 2011-03-30 夏焰明 Chinese medical drug air sanitizing preparation and preparation method thereof
CN102057956A (en) * 2009-11-14 2011-05-18 周福伟 Sterilizing fumigation preparation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1179965A (en) * 1997-05-15 1998-04-29 李传良 Antiviral anti-influenza spray and its preparing method
CN101990913A (en) * 2009-08-29 2011-03-30 夏焰明 Chinese medical drug air sanitizing preparation and preparation method thereof
CN102057956A (en) * 2009-11-14 2011-05-18 周福伟 Sterilizing fumigation preparation

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