CN102511425A - Underwater atomization disinfection drug administration method used for aquiculture - Google Patents

Underwater atomization disinfection drug administration method used for aquiculture Download PDF

Info

Publication number
CN102511425A
CN102511425A CN2011104555833A CN201110455583A CN102511425A CN 102511425 A CN102511425 A CN 102511425A CN 2011104555833 A CN2011104555833 A CN 2011104555833A CN 201110455583 A CN201110455583 A CN 201110455583A CN 102511425 A CN102511425 A CN 102511425A
Authority
CN
China
Prior art keywords
water
drug
medicine
closed shell
communicated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN2011104555833A
Other languages
Chinese (zh)
Other versions
CN102511425B (en
Inventor
王念民
姜作发
孙大江
霍堂斌
曲秋芝
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Heilongjiang River Fisheries Research Institute of Chinese Academy of Fishery Sciences
Original Assignee
Heilongjiang River Fisheries Research Institute of Chinese Academy of Fishery Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heilongjiang River Fisheries Research Institute of Chinese Academy of Fishery Sciences filed Critical Heilongjiang River Fisheries Research Institute of Chinese Academy of Fishery Sciences
Priority to CN2011104555833A priority Critical patent/CN102511425B/en
Publication of CN102511425A publication Critical patent/CN102511425A/en
Application granted granted Critical
Publication of CN102511425B publication Critical patent/CN102511425B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/80Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
    • Y02A40/81Aquaculture, e.g. of fish

Landscapes

  • Medicinal Preparation (AREA)

Abstract

An underwater atomization disinfection drug administration method used for aquiculture relates to an underwater atomization disinfection drug administration and solves the problem that at present, when drug is added in a water body directly during aquiculture, the drug can not merge with water quickly and can not be distributed in the water body uniformly. A drug ultrasonic atomization device is communicated with the water discharge outlet of a to-be-disinfected aquiculture container, wherein the water volume of the aquiculture container is 1 to 2 m<3>; drug is prepared in the way that the drug is mixed with and dissolves in water and is mixed completely for 10 to 20 min; if the drug is water-soluble drug, the volume ratio of the drug and water is 1:50-100, and if the drug is water-insoluble drug, the volume ratio of the drug and alcohol is 1:10; then the prepared drug is filled in a liquid medicine chamber, an ultrasonic generator is started, the atomization time is 2 to 3 min, then a stirring shaft and a blade are started, and the stirring time is 0.5 to 1 min. The invention is used for aquiculture.

Description

The method that is used for the water atomization disinfection administration of aquaculture
Technical field
The present invention relates to the method for atomization disinfection administration in a kind of water.
Background technology
The effect of aquaculture process Chinese traditional medicine is the general performance of pharmaceutical chemistry character and body interphase interaction; According to different methods of administration; Can be divided into following several types; Modes such as to effect in the body (promptly through digest and assimilate or work through blood (body) liquid etc.) and comprehensive function, spill method, extension bag (basket) method, pond retting, an infusion method for sprinkle (spray) with sterilization, control medicine, dip in bubble method, semar technique, mix the bait oral medication by the mode of main medication to the effect of engine body exterior, medicine for medicine, injection, fish body investment, preceding four kinds of methods mainly directly add water body to medicine; Utilize aqueous medium that medicine is spread in water body, until being distributed to whole water body; For big water body, then form higher partly sterilised of drug concentration or treatment region.Dip in bubble, smear rule and utilize the higher concentration soup to be stained with to be applied to body table affected part, the purpose that reaches treatment is used for wound or bleb, tumour etc.Investment mainly reaches the affected part through getting into digestive tract, blood or body fluid in oral, the injection of companion's bait, the body, to reach therapeutic purposes.
The shortcoming of several kinds and prescription formula is with not enough:
1, mainly rely on medicine and water molecules speed, and by water body flow, extraneous diffusion conditionses such as hydrone motion and temperature, can't directly use as sprinkling (spray) for hydrophobic medicine and to spill, to soak and macerate, hang bag (basket) method etc.; Sprinkle (spray) and spill factors such as also should be noted that weather and wind direction.
2, as hanging bag (basket), pond retting or rely on Chinese herbal medicine effective ingredients in water, to dissociate out naturally or lean on bulk powder shape drug slow to be dissolved out, onset slowly, long action time; As run into summer high temperature and also possibly water quality degenerated because corrupt (rotting) causes toxic and side effect, this several method is not suitable for finite aquifer.
3, infusion method relies on concentration gradient to be spread to low by height, lean on artificial the stirring, and drug solution concentration is generally very low, and the little diffusion of gradient difference is slow, and changes to the water body that contains medicine after need aquaculture product being fished for mostly.
4, for the big soup of concentration through dip in bubble, semar technique need need a large amount of manpowers, and in the process of fishing for, aggravate sick and wounded by the tail operation; In operating process, need anesthesia more, the leaving water gymnastics is done and will the fish body be kept certain attitude, flows in the lymphogranuloma inguinale or the gill to avoid soup, causes poisoning.
5, companion's bait oral medication need be added medicine in the bait to, and its effect depends on the ingestion ability etc. that medicine dissociates water-soluble speed, adds the palatability of medicinal bait and culture object in the bait retention time, from bait with bait binding ability, drug concentration.Especially to the poor of ill ingestion ability difference.
6, injection and investment need be by the tail operations, and consuming time taking a lot of work is inappropriate for the bigger or individual small individuals of quantity, simultaneously operating technology had relatively high expectations, otherwise very easily causes wound even fatal.
Summary of the invention
The purpose of this invention is to provide a kind of method that is used for the water atomization disinfection administration of aquaculture, medicine and water can't merge fast and medicine can't be evenly distributed on the problem in the water body when medicine directly being added water body to solve in the present aquaculture.
The present invention solves the problems of the technologies described above the technical scheme of taking to be: said method comprises the steps: that it accomplishes based on the medicine ultrasonic atomizing device; Said device comprises supersonic generator and the compressor that is used to vacuumize, vacuum mixing chamber, apotheca, soup chamber, first pipeline, outlet pipe, shower nozzle, flowing water Valve, plectane valve, second pipeline and water pump, and vacuum mixing chamber comprises closed shell, shaft and blade; The top of closed shell is provided with the water inlet with flowing water Valve control; The sidewall of closed shell is communicated with the top of apotheca through first pipeline, and apotheca is located at the top of soup chamber, and the top of soup chamber 5 and apotheca corresponding position are provided with the plectane valve; The soup chamber is located at the top of supersonic generator; And the bottom of soup chamber is communicated with the internal chamber of supersonic generator, and the compressor that is used to vacuumize is housed on the sidewall of closed shell, and shaft and blade are housed in the closed shell; Blade is contained on the shaft; Closed shell is communicated with an end of water pump through second pipeline, and the other end of water pump is communicated with an end of outlet pipe, and the other end of the outlet pipe shower nozzle interior with being located at sterile pot is connected;
Step 1, the medicine ultrasonic atomizing device is communicated with the discharge outlet of aquaculture container to be sterilized, the water body volume is 1-2m in the aquaculture container 3
Step 2, compounding pharmaceutical: with medicine and water mixed dissolution, fully mix, incorporation time is 10-20min, and when medicine was water soluble drug, medicine was 1 with the volume parts ratio of water: 50-100; When medicine was water-insoluble medicine, medicine was 1: 10 with the volume parts ratio of ethanol;
Step 3, that the medicine for preparing is contained in soup is indoor; Start supersonic generator; The power of supersonic generator is 200W (220V), and nebulisation time is 2-3min, restarts shaft and blade; Mixing time is 0.5-1min, makes in the aquaculture container drug concentration of water body reach hundred orders of magnitude very much.
The present invention has following beneficial effect: the principle of the invention is that to utilize the ultrasonic atomizatio technology be the vaporific drop that the liquid pharmaceutical that will prepare in advance of cavitation forms the diameter micron diameter; Join in the water body; Carry out administration and disinfectant method; Culture object move about, in breathing and the phagocytosis; Make the soup of atomizing be enriched in the fish gill or through swallowing or modes such as the bubble coalescence absorption fish body and immersions that raise through the soup ambient concentration reach and act ons the affected part, make the disease fish obtain to treat, the while also can be used for the aquatic products prevention of damage by disease.
Description of drawings
Fig. 1 is the overall structure sketch map of device used herein.
Embodiment
Embodiment one: combine Fig. 1 that this embodiment is described, the method for this embodiment comprises the steps:
It is accomplished based on the medicine ultrasonic atomizing device; Said device comprises supersonic generator 1 and the compressor 2 that is used to vacuumize, vacuum mixing chamber, apotheca 4, soup chamber 5, first pipeline 6, outlet pipe 7, shower nozzle 8, flowing water Valve 9, plectane valve 10, second pipeline 14 and water pump 15, and vacuum mixing chamber comprises closed shell 3-1, shaft 3-2 and blade 3-3; The top of closed shell 3-1 is provided with the water inlet 3-4 with flowing water Valve 9 controls; The sidewall of closed shell 3-1 is communicated with the top of apotheca 4 through first pipeline 6, and apotheca 4 is located at the top of soup chamber 5, and the top of soup chamber 5 and apotheca 4 corresponding positions are provided with plectane valve 10; Soup chamber 5 is located at the top of supersonic generator 1; And the bottom of soup chamber 5 is communicated with the internal chamber of supersonic generator 1, and the compressor 2 that is used to vacuumize is housed on the sidewall of closed shell 3-1, and shaft 3-2 and blade 3-3 are housed in the closed shell 3-1; Blade 3-3 is contained on the shaft 3-2; Closed shell 3-1 is communicated with an end of water pump 15 through second pipeline 14, and the other end of water pump 15 is communicated with an end of outlet pipe 7, and the other end of outlet pipe 7 shower nozzle 8 interior with being located at sterile pot is connected;
Step 1, the medicine ultrasonic atomizing device is communicated with the discharge outlet of aquaculture container to be sterilized, the water body volume is 1-2m in the aquaculture container 3
Step 2, compounding pharmaceutical: with medicine and water mixed dissolution, fully mix, incorporation time is 10-20min, and when medicine was water soluble drug, medicine was 1 with the volume parts ratio of water: 50-100; When medicine was water-insoluble medicine, medicine was 1: 10 with the volume parts ratio of ethanol;
Step 3, the medicine for preparing is contained in the soup chamber 5; Start supersonic generator 1; The power of supersonic generator 1 is 200W (220V), and nebulisation time is 2-3min, restarts shaft 3-2 and blade 3-3; Mixing time is 0.5-1min, makes in the aquaculture container drug concentration of water body reach hundred orders of magnitude very much.
Said device also comprises anti-dry probe 11, first valve 12 and second valve 13; Anti-dry probe 11 is located in the supersonic generator 1; First pipeline 6 is provided with first valve, 12, the second pipelines 14 near closed shell 3-1 place and is provided with second valve 13 near closed shell 3-1 place.
Embodiment two: combine Fig. 1 that this embodiment is described, the drop that sprays in the shower nozzle of this embodiment (8) is a gas liquid mixture, and the volume of drop is 0.2-0.35m 3, the advantage of this step is can promote the accelerated motion in breeding water body of gas medicine mixed liquor through spraying, makes its quick mixing.Other embodiment is identical with embodiment one.

Claims (2)

1. a method that is used for the water atomization disinfection administration of aquaculture is characterized in that said method comprises the steps:
It is accomplished based on the medicine ultrasonic atomizing device; Compressor (2), vacuum mixing chamber, apotheca (4), soup chamber (5), first pipeline (6), outlet pipe (7), shower nozzle (8), flowing water Valve (9), plectane valve (10), second pipeline (14) and water pump (15) that said device comprises supersonic generator (1) and is used to vacuumize; Vacuum mixing chamber comprises closed shell (3-1), shaft (3-2) and blade (3-3); The top of closed shell (3-1) is provided with the water inlet (3-4) with flowing water Valve (9) control; The sidewall of closed shell (3-1) is communicated with the top of apotheca (4) through first pipeline (6), and apotheca (4) is located at the top of soup chamber (5), and the top of soup chamber (5) and apotheca (4) corresponding position are provided with plectane valve (10); Soup chamber (5) is located at the top of supersonic generator (1); And the bottom of soup chamber (5) is communicated with the internal chamber of supersonic generator (1), and the compressor (2) that is used to vacuumize is housed on the sidewall of closed shell (3-1), and shaft (3-2) and blade (3-3) are housed in the closed shell (3-1); Blade (3-3) is contained on the shaft (3-2); Closed shell (3-1) is communicated with an end of water pump (15) through second pipeline (14), and the other end of water pump (15) is communicated with an end of outlet pipe (7), and the other end of outlet pipe (7) shower nozzle (8) interior with being located at sterile pot is connected.
Step 1, the medicine ultrasonic atomizing device is communicated with the discharge outlet of aquaculture container to be sterilized, the water body volume is 1-2m in the aquaculture container 3
Step 2, compounding pharmaceutical: with medicine and water mixed dissolution, fully mix, incorporation time is 10-20min, and when medicine was water soluble drug, medicine was 1 with the volume parts ratio of water: 50-100; When medicine was water-insoluble medicine, medicine was 1: 10 with the volume parts ratio of ethanol;
Step 3, the medicine for preparing is contained in the soup chamber (5); Start supersonic generator (1); The power of supersonic generator (1) is 200W, and nebulisation time is 2-3min, restarts shaft (3-2) and blade (3-3); Mixing time is 0.5-1min, makes in the aquaculture container drug concentration of water body reach hundred orders of magnitude very much.
2. according to the said method that is used for the water atomization disinfection administration of aquaculture of claim 1, it is characterized in that the drop that sprays in the shower nozzle (8) is a gas liquid mixture, the volume of drop is 0.2-0.35m 3
CN2011104555833A 2011-12-30 2011-12-30 Underwater atomization disinfection drug administration method used for aquiculture Expired - Fee Related CN102511425B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2011104555833A CN102511425B (en) 2011-12-30 2011-12-30 Underwater atomization disinfection drug administration method used for aquiculture

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2011104555833A CN102511425B (en) 2011-12-30 2011-12-30 Underwater atomization disinfection drug administration method used for aquiculture

Publications (2)

Publication Number Publication Date
CN102511425A true CN102511425A (en) 2012-06-27
CN102511425B CN102511425B (en) 2013-07-03

Family

ID=46282734

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2011104555833A Expired - Fee Related CN102511425B (en) 2011-12-30 2011-12-30 Underwater atomization disinfection drug administration method used for aquiculture

Country Status (1)

Country Link
CN (1) CN102511425B (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102747607A (en) * 2012-07-07 2012-10-24 紫罗兰家纺科技股份有限公司 Household article adopting probiotics for finishing and bacteria resisting, manufacturing method and equipment realizing method
CN104823885A (en) * 2015-04-22 2015-08-12 河南科技大学 Dosing device and dosing method
CN109463373A (en) * 2018-12-13 2019-03-15 赖发兰 A kind of insect prevention medicament spray appliance used for aquiculture
CN110999832A (en) * 2019-11-27 2020-04-14 南宁市蔡哥水产科技有限公司 Fish body surface disease treatment device

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000058022A1 (en) * 1999-03-28 2000-10-05 Liposol Ltd. A method and apparatus for nebulizing a liquid particularly useful for the aerosol delivery of biopharmaceuticals
JP2006149995A (en) * 2004-11-26 2006-06-15 Yoshimi Sano Technique for sterilization/deodorization
CN201008814Y (en) * 2006-12-30 2008-01-23 吴益祥 Externally used drug liquid sprayer for fishing
CN201510374U (en) * 2009-09-18 2010-06-23 李海国 Multifunctional micro mist medication dispenser

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000058022A1 (en) * 1999-03-28 2000-10-05 Liposol Ltd. A method and apparatus for nebulizing a liquid particularly useful for the aerosol delivery of biopharmaceuticals
JP2006149995A (en) * 2004-11-26 2006-06-15 Yoshimi Sano Technique for sterilization/deodorization
CN201008814Y (en) * 2006-12-30 2008-01-23 吴益祥 Externally used drug liquid sprayer for fishing
CN201510374U (en) * 2009-09-18 2010-06-23 李海国 Multifunctional micro mist medication dispenser

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
吴亨进: "超声波喷雾消毒器对养殖场空气消毒效果观察", 《中国畜禽种业》, vol. 6, no. 2, 26 April 2010 (2010-04-26) *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102747607A (en) * 2012-07-07 2012-10-24 紫罗兰家纺科技股份有限公司 Household article adopting probiotics for finishing and bacteria resisting, manufacturing method and equipment realizing method
CN104823885A (en) * 2015-04-22 2015-08-12 河南科技大学 Dosing device and dosing method
CN104823885B (en) * 2015-04-22 2017-04-12 河南科技大学 Dosing device and dosing method
CN109463373A (en) * 2018-12-13 2019-03-15 赖发兰 A kind of insect prevention medicament spray appliance used for aquiculture
CN109463373B (en) * 2018-12-13 2021-06-22 赖发兰 Insect-preventing agent spraying equipment for aquaculture
CN110999832A (en) * 2019-11-27 2020-04-14 南宁市蔡哥水产科技有限公司 Fish body surface disease treatment device

Also Published As

Publication number Publication date
CN102511425B (en) 2013-07-03

Similar Documents

Publication Publication Date Title
CN102511425B (en) Underwater atomization disinfection drug administration method used for aquiculture
CN105722974A (en) Method for inducing pluripotent stem cells and pluripotent stem cells prepared by said method
US20110260347A1 (en) Method for producing liposomal drugs and a device for producing a liposome
CN110433133A (en) The cannabidiol nasal formulations for treating posttraumatic stress disorder
CN113694175A (en) Sophora flavescens base ionic liquid conotoxin polypeptide solution, preparation method and application thereof
CN108991243A (en) A kind of solid, water soluble composite essential oil and preparation method thereof
CN105495570B (en) A kind of manufacturing method of dendrobium candidum suspended gel
CN202387631U (en) Ultrasonic medicine atomization device for aquaculture and container matched with same in use
CN102580885B (en) Ultrasonic medicine atomizer for aquaculture and container used with same
TWI311488B (en)
CN1709236A (en) Fat emulsion containing docetaxel and its preparing method
CN104096231A (en) Targeting nano sono-sensitizer and preparation method thereof
CN1120908A (en) Choice seafood extract product and its production process and uses
CN107837400A (en) A kind of novel nano genophore and preparation method thereof
WO2014058329A1 (en) Compositions based on hypophyseal hormones for adding to infusion fluids
CN106265599A (en) The preparation technology of a kind of peoniflorin wheat gliadin nanoparticle and purposes
CN108926709A (en) A kind of nanometer cooperative therapeutic agent and the preparation method and application thereof
CN108904592A (en) A kind of pure Chinese medicine antivirus veterinary herbal mixture concentrate and oral solution and preparation method thereof
CN101856537A (en) Ultrasound mediated mucosal drug delivery system
CN104257913A (en) Traditional Chinese medicine concentrated solution for treating cow mastitis and coating agent prepared from concentrated solution
CN110038090A (en) A kind of compound celery oil self-emulsifying soft capsule and preparation method thereof with antigout effect
CN205492139U (en) Salmon is bred with spouting medicine device
CN111973732B (en) Immediate release preparation for targeted therapy of hyperlipidemic acute pancreatitis
CN109044974A (en) Coat nano vesicle preparations and its application of vitamin D and vitamin K
CN104784152B (en) A kind of Thiamphenicol micro-capsule and preparation method and application

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20130703

Termination date: 20141230

EXPY Termination of patent right or utility model