CN102499962A - Traditional Chinese medicine for treating rheumatoid arthritis - Google Patents

Traditional Chinese medicine for treating rheumatoid arthritis Download PDF

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Publication number
CN102499962A
CN102499962A CN2011104433821A CN201110443382A CN102499962A CN 102499962 A CN102499962 A CN 102499962A CN 2011104433821 A CN2011104433821 A CN 2011104433821A CN 201110443382 A CN201110443382 A CN 201110443382A CN 102499962 A CN102499962 A CN 102499962A
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chinese medicine
chinese
preparation
rheumatism
compositions
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CN2011104433821A
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Chinese (zh)
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尤誉环
李敏之
尤清瑞
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Abstract

The invention relates to a Chinese medicinal preparation composition, in particular to a traditional Chinese medicinal preparation composition for treating rheumatoid arthritis. The composition is prepared from the following traditional Chinese medicinal raw materials in percentage by weight: 10-20% of Schizophragma integrifolium, 10-20% of dragon's blood, 15-25% of fructus liquidambaris, 25-35% of garden balsam stem, 10-20% of radix clematidis and 3-6% of musk.

Description

A kind of treatment rheumatoid Chinese medicine
Technical field:
The present invention relates to a kind of Chinese medicine preparation compositions, the rheumatoid Chinese medicine preparation compositions of particularly a kind of treatment.
Background technology:
Rheumatoid arthritis (RA) claim rheumatoid again, is to serve as the autoimmune disease that does not still have the specific diagnosis index of main performance with pathological changes outside chronic, symmetry multi-joint synovitis and the joint.Because etiology unknown so far, so clinical treatment makes the doctor feel more thorny, produce effects is slow, cure rate is low; Recurrence, disability rate height have been generally acknowledged by the public.Thereby by helpless be called " the not dead cancer " of people with getting.Doctor trained in Western medicine conventional therapy nonsteroidal anti-inflammatory agent (NSAID, acts on antirheumatic (SAAPD), glucocorticoid and biological preparation etc. slowly and can play mitigation to most of case; But its side effect of life-time service can not be ignored; And most of patients is prone to medicine is produced dependence; Medication is effective, end-of-dose failure, makes doctor and patient beat one's brains.The rheumatoid Chinese medicine composition of many treatments is arranged in the prior art, like the description in the following Chinese patent:
200310105379 The rheumatoid Chinese medicine composition of a kind of treatment
200710053818 Treatment rheumatism, rheumatoid Atoxic Chinese medicine composition
200910229970 A kind of Chinese medicine composition of treating rheumatism, rheumatoid disease
200510033721 The Traditional Chinese Medicine for external application compositions of treatment rheumatic and rheumatoid and chronic pain
200510011140 A kind of treatment rheumatism or rheumatoid Chinese medicine composition and preparation method thereof
200710175896 A kind of treatment rheumatism or rheumatoid Chinese medicine composition plaster and preparation method thereof
200810090863 A kind of treatment rheumatism and rheumatoid Chinese medicine composition
200810124772 A kind of Chinese medicine composition of treating rheumatoid disease
02131440 A kind of medicine of treating rheumatoid, rheumatism
200310114642 A kind of Chinese medicine composition of treating rheumatoid arthritis
99103102 A kind of pharmaceutical composition of treating rheumatism, rheumatoid arthritis and preparation method thereof
02128482 A kind of Chinese medicine composition of treating rheumatism, rheumatoid arthritis
02157390 A kind of Chinese medicine composition of treating rheumatoid arthritis and preparation method thereof and method of quality control
200310105616 The Chinese medicine composition of treatment rheumatism, rheumatoid arthritis
200510003140 The Chinese medicine composition of treatment rheumatism, rheumatoid arthritis
200810154283 Rheumatism plaster and preparation method thereof
200810017731 A kind of Chinese medicine composition of treating rheumatoid arthritis and preparation method thereof
200910053358 A kind of Chinese medicine composition of treating rheumatoid arthritis and preparation method thereof
201010525824 Arthritic Chinese medicine composition of a kind of treatment rheumatic and rheumatoid and preparation method thereof
The Chinese patent medicine of resisting rheumatoid disease in the market is a lot, but some belongs to and cure the symptoms, not the disease, and some uses expensive composition, and some is cut and interrupt using owing to uncertain therapeutic efficacy in application process.
The invention provides a kind of determined curative effect, safe ready, little, the cheap pure traditional Chinese compound medicine of side effect.
The present invention provides a kind of Chinese medicine for external application-" No. 1, rheumatism " medicated wine.The main characteristic of said preparation be " do not take medicine, do not have an injection, externally used medicinal liquor, simple and convenient; Rapid-action, short treating period, treating both the principal and secondary aspects of a disease, cost ", peculiar to three indexs of rheumatism (RF, ESR, ASO) effect of turning out cloudy, toxic and side effects is almost nil.Through thousands of routine patient's clinical observations, always effectively reach more than 96%, three of rheumatism are turned out cloudy and are reached more than 85%.
Summary of the invention:
The present invention provides a kind of Chinese medicine for external application compositions, and said composition is prepared from the raw material of Chinese medicine medicine of following percentage by weight:
Cortex schizophragmatis integrifolii radicis 10-20%,
Sanguis Draxonis 10-20%,
Fructus Liquidambaris 15-25%,
Herba speranskiae tuberculatae 25-35%,
Radix Clematidis 10-20%,
Moschus 3-6%,
Preferably, said composition is prepared from the raw material of Chinese medicine medicine of following percentage by weight:
Cortex schizophragmatis integrifolii radicis 15%,
Sanguis Draxonis 15%,
Fructus Liquidambaris 20%,
Herba speranskiae tuberculatae 30%,
Radix Clematidis 15%,
Moschus 5%,
In above composition the of the present invention, the weight of each medicine of distinguishing the flavor of is calculated with crude drug, if be unit with the gram, above-mentioned prescription is formed the pharmaceutical preparation that can be made into a dosage schedule.
More than form being by weight as proportioning, when producing, can increasing or reduce according to corresponding proportion, can be unit with kg like large-scale production, or is unit with t (ton); Preparation can be unit with g also on a small scale.Weight can increase or reduce, but the constant rate of the raw medicinal herbs weight proportion between each composition.
The ratio of above weight proportion obtains through science screening, for especial patient, and like serious symptom or light disease, fat or modest patient, the proportioning of the amount of can corresponding adjustment forming increases or reduces being no more than 100%, and drug effect is constant basically.
Chinese medicine composition of the present invention is to process through extraction or other modes through the raw material of Chinese medicine medical material that above-mentioned prescription is formed, and processes pharmaceutically active substance; Subsequently; With this material is raw material, adds the medicine acceptable carrier when needing, and processes according to the routine techniques of galenic pharmacy.Said active substance can obtain through extracting raw material of Chinese medicine respectively; Also can obtain through co-extracted raw material of Chinese medicine medical material; Also can obtain through other modes; As: through pulverize, squeeze, grind, sieve, methods such as percolation, extraction, water are carried, alcohol extraction, ester are carried, chromatography obtain, these active substances can be the material of extractum form, can be that dry extract also can be a fluid extract, process different concentration according to the different needs decision of preparation.
Chinese medicine composition of the present invention, preferably the pharmaceutical dosage forms of UD can be processed any pharmaceutically useful dosage form when processing pharmaceutical preparation, and these dosage forms are selected from: patch, oil preparation, medicated wine, unguentum, most preferably medicated wine.
Chinese medicine composition of the present invention, its pharmaceutically active substance makes through extracting processing, as processing in order to following method:
Get band glaze pottery vat one tool, Chinese liquor and medical material in proportion in the input cylinder, sealed, soak after 49 days medicated wine " No. 1, rheumatism ".The sealing lucifuge is deposited after the packing.
The preferred Chinese liquor (aging more than 5 years) more than 60 ° of the above Chinese liquor, the Chinese liquor consumption doubly is advisable with the 1-5 of medical material weight, and preferred 2-3 is doubly.
Pharmaceutical composition of the present invention, the effect characteristics: blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, relaxing muscles and tendons and activating QI and blood in the collateral, relieving spasm to stop pain, short three of rheumatism are turned out cloudy.
The indication of pharmaceutical composition of the present invention: aseptic pertinacious diseases such as rheumatoid arthritis, neck-shoulder pain, lumbago and leg pain, sciatica.
Model case: all adopt the medicated wine of the embodiment of the invention 1 to treat.
Li Hongmei: woman, 42 years old, morbidity at the beginning of 2003, Suixian County, Henan Province Dong Dianzhen Zhao Zhuan people from village; Be diagnosed as rheumatoid arthritis through county people's hospital, both hands articulations digitorum manus congestion and swelling pain, morning is stiff, after involve carpal joint, elbow joint and jaw joint and have a meal and need others to help mouth is strutted feeding; Through the treatment in 1 year half of Henan Prov. People's Hospital and Honghu City, Hubei Province rheumatism hospital, " No. 1, rheumatism " treatment is accepted in the symptom commentaries on classics of not getting better in October, 2004; Patient's private prosecution medication 3 days beginning produce effects, 26 days rednesses, pain, morning, stiff symptom all disappeared, and life can be taken care of oneself; Medication checks after 3 months that rheumatism 3 (RF, ESR, ASO) is all turned out cloudy, and follows up a case by regular visits to so far not recurrence.
Luo Baoping: man, 43 years old, the driver of Zhengzhou Public Traffic Co.; Morbidity in private prosecution spring in 2008, medical college one is attached institute and is diagnosed as rheumatoid arthritis through Henan, and is invalid through multi-treatment; Accepted " No. 1, rheumatism " treatment in 2009, continuous use is after 4 months, and not only the rheumatoid symptom disappears; Three indexs of rheumatism are turned out cloudy, and also fully recover after the sciatic nerve dysmenorrhea medication treatment, follow up a case by regular visits to so far that all are normal.
Cui Hongling: the woman, 38 years old, in May, 2005 morbidity was told in Zhengzhou Public Traffic Co.'s scheduling, is diagnosed as rheumatoid arthritis through worker's hospital, and continuous use was fully recovered after 3 months.
Lu Chuanting: the man, 66 years old, the vice-president of the People's Hospital, Suixian County, former Henan Province, head of the department of surgery doctor told the mid-1960s morbidity in last century; Slippers are worn in brothers' joint deformity throughout the year, and time swells bitterly; Beginning external " No. 1, rheumatism " treatment in 2007,1 month transference cure, continuous use inspection in 6 months; Three indexs of rheumatism are all normal, freedom of movement, and drug withdrawal is not recurrence so far.
Sun Xiuzhi: the woman, 58 years old, people from Luoyang City, rheumatoid arthritis is suffered from retirement when telling 18 years old.Be not interrupted treatment in 40 years, and weighed in December, 2009 during symptom when light and accept No. 1 treatment of " " rheumatism, symptom all disappeared in 33 days, and check result RF, ESR be cloudy to be changeed, ASO is by reducing to 22mm/h.
The beam red flag: the man, 44 years old, the Great Wall director of Huizhou City, Guangdong Province told and suffered from rheumatoid nearly 30 years, and " No. 1, rheumatism " treatment is accepted in outbreak repeatedly in February, 2010, and 2 take effect, 17 days transference cures, not recurrence so far.
Liu Hua: the woman, 36 years old, the gynaecologist of the People's Hospital, Huiyang, Huizhou City, Guangdong Province told and suffered from rheumatoid nearly 18 years, and seeking medical advice everywhere has no resolution, and accepts " No. 1, rheumatism " treatment in March, 2010, and 5 take effect, day transference cure surplus in the of 40, three indexs of the results suggest of having a blood test rheumatism are turned out cloudy.
Cui Xiaozhen: the woman, 77 years old, former Henan Province Suixian County department store manager told surplus sciatica, the lumbar muscle strain 30 year, and going up needs people's back of the body to send downstairs, accepts " No. 1, rheumatism " treatment in 2008, continuous use 2 months, the patient can go up downstairs freely, and symptom all disappears.
Above instance is representative case only, has above curative effect person many in addition, no longer enumerates at this.
The specific embodiment:
Below further specify the present invention through embodiment, but not as limitation of the present invention.
Embodiment 1
Cortex schizophragmatis integrifolii radicis 15g,
Sanguis Draxonis 15g,
Fructus Liquidambaris 20g,
Herba speranskiae tuberculatae 30g,
Radix Clematidis 15g,
Moschus 5g,
Method for preparing:
Get band glaze pottery vat one tool, 60 ° of Chinese liquor and medical material in 2: 1 the ratio input cylinder, sealed, soak after 49 days medicated wine " No. 1, rheumatism ".
Embodiment 2
Cortex schizophragmatis integrifolii radicis 10g,
Sanguis Draxonis 10g,
Fructus Liquidambaris 15g,
Herba speranskiae tuberculatae 25g,
Radix Clematidis 10g,
Moschus 3g,
Method for preparing:
Get band glaze pottery vat one tool, 60 ° of Chinese liquor and medical material in 5: 1 the ratio input cylinder, sealed, soak after 49 days medicated wine.
Embodiment 3
Cortex schizophragmatis integrifolii radicis 20g,
Sanguis Draxonis 20g,
Fructus Liquidambaris 25g,
Herba speranskiae tuberculatae 35g,
Radix Clematidis 20g,
Moschus 6g,
Method for preparing:
Get band glaze pottery vat one tool, 60 ° of Chinese liquor and medical material in 1: 1 the ratio input cylinder, sealed, soak after 49 days medicated wine.
Embodiment 4
Cortex schizophragmatis integrifolii radicis 15g,
Sanguis Draxonis 15g,
Fructus Liquidambaris 20g,
Herba speranskiae tuberculatae 30g,
Radix Clematidis 15g,
Moschus 5g,
Method for preparing:
95% ethanol and the medical material ratio in 2: 1 is dropped in the extraction pot; Reflux, extract, 24 hours is removed ethanol, obtains extract; With this extract as pharmaceutically active substance; Add pharmaceutical carrier in case of necessity like the penetrating agent that promotes skin absorbs etc., be prepared into unguentum according to the galenic pharmacy routine techniques, oil preparation or patch.

Claims (10)

1. a Chinese medicine preparation compositions is characterized in that, said composition is prepared from the raw material of Chinese medicine medicine of following percentage by weight:
Cortex schizophragmatis integrifolii radicis 10-20%,
Sanguis Draxonis 10-20%,
Fructus Liquidambaris 15-25%,
Herba speranskiae tuberculatae 25-35%,
Radix Clematidis 10-20%,
Moschus 3-6%.
2. according to the Chinese medicine preparation compositions of claim 1, it is characterized in that said composition is prepared from the raw material of Chinese medicine medicine of following percentage by weight:
Cortex schizophragmatis integrifolii radicis 15%,
Sanguis Draxonis 15%,
Fructus Liquidambaris 20%,
Herba speranskiae tuberculatae 30%,
Radix Clematidis 15%,
Moschus 5%,
3. according to the Chinese medicine preparation compositions of claim 1, it is characterized in that, when processing pharmaceutical preparation, can process any pharmaceutically useful dosage form.
4. according to the Chinese medicine preparation compositions of claim 1, it is characterized in that these dosage forms are selected from: patch, oil preparation, medicated wine, unguentum,
5. according to the Chinese medicine preparation compositions of claim 1, it is characterized in that, is medicated wine.
6. the Chinese medicine preparation preparation of compositions method of claim 1; It is characterized in that step is following: the raw material of Chinese medicine medical material is processed through extraction or other modes, processes pharmaceutically active substance; Subsequently; With this material is raw material, adds the medicine acceptable carrier when needing, and processes according to the routine techniques of galenic pharmacy.
7. according to the method for preparing of claim 6, it is characterized in that step is following: get band glaze pottery vat one tool, Chinese liquor and medical material in proportion in the input cylinder, sealed, soak after 49 days medicated wine, seal lucifuge after the packing and deposit.
8. according to the method for preparing of claim 6, it is characterized in that the above Chinese liquor is Chinese liquor more than 60 °, aging more than 5 years, the Chinese liquor consumption is 1-5 a times of medical material weight.
9. according to the method for preparing of claim 6, it is characterized in that the Chinese liquor consumption is 2-3 a times of medical material weight.
10. the Chinese medicine preparation compositions of claim 1 has the application in the medicine of following effect in preparation, blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, relaxing muscles and tendons and activating QI and blood in the collateral, relieving spasm to stop pain, and short three of rheumatism are turned out cloudy; Aseptic pertinacious diseases such as treatment rheumatoid arthritis, neck-shoulder pain, lumbago and leg pain, sciatica.
CN2011104433821A 2011-12-27 2011-12-27 Traditional Chinese medicine for treating rheumatoid arthritis Pending CN102499962A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102920853A (en) * 2012-11-22 2013-02-13 金秀瑶族自治县瑶医医院 Externally applied medicated wine for rheumatism and ostealgia and preparation method thereof
CN103191274A (en) * 2013-04-22 2013-07-10 朱军 Externally applied traditional Chinese medicine powder for treating lumbar disc herniation
CN105998225A (en) * 2016-06-13 2016-10-12 徐立军 Traditional Chinese medicine combination for treating rheumatiod
CN106236995A (en) * 2016-08-25 2016-12-21 杜春响 One treats rheumatoid Chinese medicine composition and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1433782A (en) * 2002-01-22 2003-08-06 康长生 Formula of external medicine for treating rheumatism numbness pain and preparation process thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1433782A (en) * 2002-01-22 2003-08-06 康长生 Formula of external medicine for treating rheumatism numbness pain and preparation process thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
钱丽萍等: "治疗类风湿性关节炎外用制剂的研究概况", 《海峡药学》 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102920853A (en) * 2012-11-22 2013-02-13 金秀瑶族自治县瑶医医院 Externally applied medicated wine for rheumatism and ostealgia and preparation method thereof
CN102920853B (en) * 2012-11-22 2014-09-17 金秀瑶族自治县瑶医医院 Externally applied medicated wine for rheumatism and ostealgia and preparation method thereof
CN103191274A (en) * 2013-04-22 2013-07-10 朱军 Externally applied traditional Chinese medicine powder for treating lumbar disc herniation
CN103191274B (en) * 2013-04-22 2014-08-13 朱军 Externally applied traditional Chinese medicine powder for treating lumbar disc herniation
CN105998225A (en) * 2016-06-13 2016-10-12 徐立军 Traditional Chinese medicine combination for treating rheumatiod
CN106236995A (en) * 2016-08-25 2016-12-21 杜春响 One treats rheumatoid Chinese medicine composition and preparation method thereof

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