CN102499941A - Decontamination bag for skin radioactive contamination - Google Patents
Decontamination bag for skin radioactive contamination Download PDFInfo
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- CN102499941A CN102499941A CN201110319786XA CN201110319786A CN102499941A CN 102499941 A CN102499941 A CN 102499941A CN 201110319786X A CN201110319786X A CN 201110319786XA CN 201110319786 A CN201110319786 A CN 201110319786A CN 102499941 A CN102499941 A CN 102499941A
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Abstract
The invention relates to the technical field of medical instruments and in particular relates to a decontamination bag for radionuclide contamination of skin and wounds. The invention discloses a decontamination bag for skin radioactive contamination, which comprises a water absorbent pad and a decontamination liquid. The invention is characterized in that the decontamination liquid is an aqueous solution containing 0.5% to 10% of EDTA, 0.5% to 10% of citric acid, 0.5% to 20% of bleaching powder and 0.5% to 10% of fatty alcohol polyoxyethylene ether sodium sulfate. The decontamination bag is available in disposable package and has the characteristics of having a small size and being convenient to carry and store and convenient to use. The decontamination bag can eliminate radionuclide contamination of skin and wounds without needing water washing, reduces secondary contamination, has good decontamination effects, and is applied to workers of nuclear power, nuclear reactors and radiation devices in both army and local areas for radiation decontamination in case of nuclear emergency.
Description
Technical field
The present invention relates to technical field of medical instruments, be specifically related to a kind of decontamination bag when being used for skin and wound radionuclide and being infected with.
Background technology
At present, existing more sophisticated military affairs of normal body surface decontamination of personnel and the decontamination of large tracts of land region and commercial technology, and technological for the decontamination of small-sized sensor and personnel's radioactive pollution wound, also be in the development exploratory experiment stage.For this reason, endeavour both at home and abroad to seek to sensitivity equipment and effective and suitable technology and the equipment thereof of personnel's wound decontamination.External skin detergent commonly used has porous belts, bar-shaped soap, waterfree hand cleaning agent, soft brush or LAVA soap; Russia has been equipped with the IPP-3 disinfection box and has been used for individual soldier's decontamination; The M291 skin degerming bag of U.S. development is made up of the sack of a purse-type, in adorn 6 pouches, a non-woven fibre mat that is full of disinfectant is arranged in each pouch; Can carry out complete skin degerming 3 times, can be to the decontamination of meeting an urgent need of skin and contaminated wound.The RDS2000 decontamination solution of the U.S. is a kind of novel concentrated type decontamination solution; Form by two kinds of compositions (polydextrose surfactant and citric acid-citrate buffer solution), be used for the decontamination on radioactive pollution surface, when using RDS2000; Become aqueous solution earlier or become foam; Be used further to surface decontamination, after one period response time, use high pressure water spray nozzle to wash the decontamination solution that contains radioactive substance.
China's decontamination technology development situation is compared also relatively low with developed countries, the decontaminant that is usually used in removing radioactive substance comprises detergent, chelating agent etc., is modulated into water according to a certain percentage usually and eliminates liquid and use.Detergent has dodecylbenzene sodium sulfonate and sodium alkyl sulfonate etc.; In aqueous solution, can reduce the surface tension of water; And effects such as moistening, emulsifying, dispersion, foaming take place, and can strengthen the effect of the elimination radioactive contamination of water, be specially adapted to elimination to the grease surface.Detergent also comprises soda acid with dirt-removing power etc.Chelating agent has sodium hexameta phosphate, sodium ethylene diamine tetracetate (EDTA), tetrasodium pyrophosphate, sodium tripolyphosphate etc., can with many metal ion effects, generate can be water-soluble stable comple.Utilize this character of complex, the radioactive substance of body surface is transferred to eliminated in the liquid, reach and eliminate the purpose of being infected with.Chelating agent usually and detergent be used.During elimination, should be according to eliminating object, being infected with and selecting suitable remover in situation and season etc.Domestic skin radioactive-pollutant eliminating detergent goods commonly used (decontamination solution, decontamination soap etc.) are used for being infected with of healthy body surface mostly, and function is comparatively single, and pH value weak acid or weak base are not suitable for the radioactive-pollutant eliminating detergent of wound; And generally all need use preceding situ configuration, can incur loss through delay some times, and widely apply flushing with clean water, decontaminating effect is general, and the secondary pollution of generation is many, is unfavorable for follow-up processing.Fast and effeciently remove radioactive contaminant, to reducing the radioactivity complex injury, it is very important winning and rescuing treatment time.At present domestic also not developing need not washing, the emergent decontamination product of radioactive contamination that physical absorption is merged with chemical decontamination principle.
Summary of the invention
Technical problem to be solved by this invention provides a kind of novel decontamination bag that is applicable to the radioactive contamination emergency processing, can directly in case of emergency remove the radioactive pollution of skin and wound.
Be the above-mentioned technical problem that solves; The invention discloses a kind of skin radioactive contamination decontamination bag; It comprises adsorptive pads and decontamination solution, it is characterized in that said decontamination solution is the aqueous solution of the citric acid, 0.5-20% bleaching powder and the 0.5-10% polyoxyethylenated alcohol sodium sulfate that contain 0.5-10%EDTA, 0.5-10%.
The prescription of decontamination solution according to the invention is a mixture, mainly comprises EDTA, citric acid, polyoxyethylenated alcohol sodium sulfate etc., and pH value is neutral, action temperature with, right
131I,
60The soil removal efficiency of Co is high.Decontamination solution according to the invention not only can be used for the radiation decontamination of skin, also can be used for the radiation decontamination of wound.
In certain embodiments, said decontamination solution can be preferably citric acid, 0.5-20% bleaching powder and the 0.5-10% polyoxyethylenated alcohol sodium sulfate of 0.5-10%EDTA, 0.5-10%.
In certain embodiments, said decontamination solution can be preferably citric acid, 1-18% bleaching powder and the 1-8% polyoxyethylenated alcohol sodium sulfate of 1-8%EDTA, 1-8%.
In certain embodiments, said decontamination solution can be preferably citric acid, 4-10% bleaching powder and the 5-6% polyoxyethylenated alcohol sodium sulfate of 1.5-3%EDTA, 2-3%.
On the other hand, the invention also discloses a kind of skin radioactive contamination decontamination bag, it is characterized in that comprising described decontamination solution.But said skin radioactive contamination decontamination bag also comprises adsorptive pads, can take adsorptive pads to separate packing or adsorptive pads with decontamination solution and soak and contain decontamination solution packing.
Adsorptive pads according to the invention can be weaving fiber pad or non-woven fibre mat or microporous sponge, wherein preferred microporous sponge.The microporous sponge water absorption is strong, contacts softly, has softness, and zest is little, and radionuclide is had good physisorption, can the physical absorption of sponge and the chemical decontamination decontamination principle of mixing decontamination solution be combined, and clean effect is strong.
Adsorptive pads according to the invention can be virtually any size or shape, wherein preferred 10-25cm * 10-25cm, and 15cm * 15cm most preferably is so that use and pack.
Decontamination bag according to the invention is mainly used in the radioactive-pollutant eliminating detergent of skin, wound, can be through saving oneself, rescuing mutually, and the very first time is removed the radioactive pollution of wound, avoids degree of depth internal radiation, reduces wound infection and secondary pollution.Decontamination bag according to the invention is taked non-returnable container, have volume little, be easy to carry and preservation, characteristics convenient to use.When the radionuclide that the present invention removes skin and wound is infected with; Need not washing, the secondary pollution of generation is few, and clean effect is good; Configurable army and the local personnel that are engaged in radiation works such as nuclear power, nuclear reactor, radiological unit use, so that in emergency circumstances implement radiation decontamination in nuclear accident.
The specific embodiment
Below in conjunction with specific embodiment, further set forth the present invention.These embodiment only be used to the present invention is described and be not used in the restriction scope of the present invention.The experimental technique of unreceipted actual conditions in the following example is usually according to the normal condition or the condition of advising according to manufacturer.Only if definition separately, the same meaning that employed all specialties and scientific words and one skilled in the art are familiar with in the literary composition.In addition, any with the institute similar content of putting down in writing or the equalization method and material all can be applicable in the inventive method.The usefulness that preferable implementation method described in the literary composition and material only present a demonstration.
Embodiment 1, decontaminating effect experiment
1, radionuclide choosing and obtaining
Buy CoCl
2, through the LDR fission neutron (
252Cf, absorbed dose rate are 0.35mGy/h) shine February, produce activation products
60Co,
131I is provided by Huangpu District central hospital.
2, the foundation of wound surface scratch model
The Fructus Foeniculi pig, 40mg/kg, the pentobarbital sodium lumbar injection, preserved skin is done skin well shape otch.
3, the screening of physical material
Choose microporous sponge, non-woven fabrics, hospital gauze (having high absorption capacity, the gentle material of while contact surface), get the material of same area, same weight respectively, drip normal saline to oozing out, relatively water absorption; The Fructus Foeniculi pig, preserved skin, cutting 3cm * 3cm is divided into 4 groups of (blank control group, sponge wiping group, non-woven fabrics wiping group, hospital gauze wiping group) experimental grouies and respectively is coated with 150 μ l's
60Co, 30 μ l
131I mixing radioactive nucleus cellulose solution, 3 kinds of physical material wipings respectively, measurement wiping front and back abrasion
60Co,
131I soil removal efficiency, relatively absorbability.The result is visible, and gauze group and non-woven fabrics group are in high, medium and low dose groups, and be right
60Co,
131The clean effect of I is similar, and sponge group clean effect is apparently higher than gauze group and non-woven fabrics group, and is best with the high dose group clean effect.(referring to table 1,2)
C
0: the Co content (mg) on Corii Sus domestica surface before the decontamination
C
1: the Co content (mg) on Corii Sus domestica surface after the decontamination
Table 1: physical material is right
60The absorption soil removal efficiency (%) of Co
Table 2: physical material is right
131The absorption soil removal efficiency (%) of I
5, mix the preparation of decontamination solution group different component
The mixing decontamination solution (aqueous solution) of preparation different component is divided into 8 groups.
The citric acid of a:1%EDTA+1%+1% bleaching powder+1% polyoxyethylenated alcohol sodium sulfate;
B:8%EDTA, 8% citric acid, 8% bleaching powder and 8% polyoxyethylenated alcohol sodium sulfate;
C:1.5%EDTA, 3% citric acid, 6% bleaching powder and 3% polyoxyethylenated alcohol sodium sulfate;
D:6%EDTA, 4% citric acid, 4% bleaching powder and 8% polyoxyethylenated alcohol sodium sulfate;
E:3%EDTA, 7% citric acid, 6% bleaching powder and 6% polyoxyethylenated alcohol sodium sulfate;
F:2%EDTA, 4% citric acid, 3% bleaching powder and 5% polyoxyethylenated alcohol sodium sulfate;
G:3%EDTA, 2% citric acid, 3% bleaching powder and 6% polyoxyethylenated alcohol sodium sulfate;
H:1.5%EDTA, 2% citric acid, 3% bleaching powder and 5% polyoxyethylenated alcohol sodium sulfate.
6, decontaminating effect test
6.1 the preparation of different formulations decontamination solution
Prepare different decontamination solutions; Be divided into 5 groups of matched groups, A, B, C, D, matched group: distilled water, A group: 5% soap water group; B group: 1.5%EDTA solution+4% polyoxyethylenated alcohol sodium sulfate; The C group: 2% citric acid solution+4% polyoxyethylenated alcohol sodium sulfate, the D group: mix the decontamination solution group, each group is fully mixed the back and is soaked microporous sponge.
6.2 test decontaminating effect
The Fructus Foeniculi pig, preserved skin, cutting 3cm * 3cm wound is coated with 150 μ l's
60Co, 30 μ l
131I mixing radioactive nucleus cellulose solution, respectively group is used the microporous sponge wiping of soaking different decontamination solutions respectively, measurement wiping front and back abrasion
60Co,
131I soil removal efficiency, relatively dirt-removing power.The result shows: right
60Co,
131The decontamination of I, high, medium and low dose groups no matter, the clean effect of decontamination bag is apparently higher than matched group soap water group (p＜0.01); Wherein, especially with mixing formula group (D group) soil removal efficiency apparently higher than other the prescription decontamination solution group (p＜0.01) (referring to table 3,4)
Table 3: different formulations decontamination bag is right
60The absorption soil removal efficiency (%) of Co
Table 4: different formulations decontamination bag is right
131The absorption soil removal efficiency (%) of I
Embodiment 2, irritant experiment
1, wound irritant experiment:
New zealand rabbit, 8, male and female half and half, the back diamond wool is cut short the back QUMAO; Each 3cm * 3cm about the QUMAO scope is behind half rabbit skin degerming, with sand paper friction, the degree of being with the oozing of blood; Be divided into matched group (intact skin group I, damaged skin group II), experimental group (intact skin group III, damaged skin group IV), the artificial wound of making is got combined group decontamination solution 0.5ml (g) and directly is coated on the wound; With two layers of gauze (2.5cm * 2.5cm) covers with one deck cellophane, fixing, opposite side skin is smeared negative control as contrast; Apply 4h, after the off-test, remove residual given the test agent with warm water.Behind the removing given the test agent 1,24,48,72h observe the dermoreaction that gives the given the test agent position respectively, judge the wound stimulus intensity.Standard integral according to skin erythema, edema formation, wound recovery extent carries out the overall merit of decontamination solution stimulation.Total mark 0-3 is the I level, and 4-6 is the II level, and 7-9 is the III level.The rabbit acute skin irritation test shows: to the influence of new zealand rabbit wound skin surface healing, decontamination experimental group and normal saline matched group are at the wound stimulus intensity no significant difference (p＞0.05) of 1h, 24h, 48h and 72h.(referring to table 5)
Table 5: rabbit acute skin irritation test
Scope of the present invention does not receive the restriction of said specific embodiments, and said embodiment also comprises the method and the component of functional equivalent only as the single example of illustrating various aspects of the present invention in the scope of the invention.In fact, except content as herein described, those skilled in the art can easily grasp multiple improvement of the present invention with reference to the description and the accompanying drawing of preceding text.Said improvement also falls within the scope of appended claims.Every piece of list of references that preceding text are mentioned is listed this paper in as a reference all in full.
Claims (10)
1. skin radioactive contamination decontamination bag; It comprises adsorptive pads and decontamination solution, it is characterized in that said decontamination solution is the aqueous solution of the citric acid, 0.5-20% bleaching powder and the 0.5-10% polyoxyethylenated alcohol sodium sulfate that contain 0.5-10%EDTA, 0.5-10%.
2. skin radioactive contamination decontamination bag as claimed in claim 1, its decontamination solution can be preferably citric acid, 1-18% bleaching powder and the 1-8% polyoxyethylenated alcohol sodium sulfate of 1-8%EDTA, 1-8%.
3. skin radioactive contamination decontamination bag as claimed in claim 2, its decontamination solution can be preferably citric acid, 3-15% bleaching powder and the 3-6% polyoxyethylenated alcohol sodium sulfate of 1.5-6%EDTA, 1.5-6%.
4. skin radioactive contamination decontamination bag as claimed in claim 3, its decontamination solution can be preferably citric acid, 4-10% bleaching powder and the 5-6% polyoxyethylenated alcohol sodium sulfate of 1.5-3%EDTA, 2-3%.
5. skin radioactive contamination decontamination bag as claimed in claim 1 is characterized in that said skin radioactive contamination decontamination bag can take adsorptive pads to separate packing or adsorptive pads with decontamination solution and soak and contain decontamination solution packing.
6. skin radioactive contamination decontamination bag as claimed in claim 1 is characterized in that said adsorptive pads can be weaving fiber pad or non-woven fibre mat or sponge.
7. skin radioactive contamination decontamination bag as claimed in claim 1 is characterized in that said weaving fiber pad is medical husky cloth.
8. skin radioactive contamination decontamination bag as claimed in claim 1 is characterized in that said non-woven fibre mat is a non-woven fabrics.
9. skin radioactive contamination decontamination bag as claimed in claim 1 is characterized in that said sponge is a microporous sponge.
10. radioactive skin contamination decontamination bag as claimed in claim 1 is characterized in that said sponge is a microporous sponge.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110319786XA CN102499941A (en) | 2011-10-20 | 2011-10-20 | Decontamination bag for skin radioactive contamination |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110319786XA CN102499941A (en) | 2011-10-20 | 2011-10-20 | Decontamination bag for skin radioactive contamination |
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| CN102499941A true CN102499941A (en) | 2012-06-20 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106692180A (en) * | 2016-12-22 | 2017-05-24 | 珠海博纳百润生物科技有限公司 | Washing and disinfecting liquid used for emergency eye chemical burns, and preparation method thereof |
| CN107828524A (en) * | 2017-10-25 | 2018-03-23 | 沈阳中科腐蚀控制工程技术有限公司 | Nuclear pollution washing detergent and preparation method thereof |
| CN109700826A (en) * | 2019-01-16 | 2019-05-03 | 中国人民解放军海军特色医学中心 | A kind of radionuclide contamination decontaminant and its preparation method and application |
| CN112704646A (en) * | 2021-01-12 | 2021-04-27 | 中国人民解放军海军特色医学中心 | Decontamination wet tissue for radionuclide-infected skin and application thereof |
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| JP2009249376A (en) * | 2008-04-09 | 2009-10-29 | Shinichi Morimoto | Remedy for dermatophytosis |
| CN101732341A (en) * | 2009-12-21 | 2010-06-16 | 中国人民解放军海军医学研究所 | Washing-disinfecting liquid and disinfecting-washing bag thereof for radioactive skin contamination |
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2011
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| RO83288A2 (en) * | 1981-12-04 | 1984-02-21 | Intreprinderea De Medicamente,Ro | ANTIDOT GRANULA IN RADIOACTIVE CONTAMINATIONS |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106692180A (en) * | 2016-12-22 | 2017-05-24 | 珠海博纳百润生物科技有限公司 | Washing and disinfecting liquid used for emergency eye chemical burns, and preparation method thereof |
| CN107828524A (en) * | 2017-10-25 | 2018-03-23 | 沈阳中科腐蚀控制工程技术有限公司 | Nuclear pollution washing detergent and preparation method thereof |
| CN107828524B (en) * | 2017-10-25 | 2020-10-16 | 沈阳中科腐蚀控制工程技术有限公司 | Nuclear pollution cleaning detergent and preparation method thereof |
| CN109700826A (en) * | 2019-01-16 | 2019-05-03 | 中国人民解放军海军特色医学中心 | A kind of radionuclide contamination decontaminant and its preparation method and application |
| CN109700826B (en) * | 2019-01-16 | 2021-05-14 | 中国人民解放军海军特色医学中心 | Radionuclide pollution decontamination agent and preparation method and application thereof |
| CN112704646A (en) * | 2021-01-12 | 2021-04-27 | 中国人民解放军海军特色医学中心 | Decontamination wet tissue for radionuclide-infected skin and application thereof |
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Application publication date: 20120620 |