CN102488860B - Traditional Chinese medicine composition for treating chronic uremia and preparation method thereof - Google Patents

Abstract

The invention discloses a traditional Chinese medicine composition for treating chronic uremia and a preparation method thereof. The effective pharmaceutical ingredients of the traditional Chinese medicine composition for treating chronic uremia are prepared from the following raw materials by weight: 10 g of angelica, 20 g of prepared rhizome of rehmannia, 20 g of radix paeoniae, 20 g of rhizoma ligustici wallichii, 30 g of astragalus mongholicus, 10 g of caulis bambusae in taenian, 10 g of herba agastachis, 10 g of tuber pinellia, 10 g of magnolia bark, 10 g of tsaoko cardamon, 20 g of Chinese rhubarb, 10 g of Semen pharbitidis, 20 g of dried tangerine peel, 30 g of raw concha ostreae powder, 20 g of fried chickens gizzard-skin, 20 g of charred triplet, 10 g of Polyporus umbellatus, 20 g of alisma, 20 g of plantain seed, 20 g of salvia miltiorrhiza, 10 g of leech, 20 g of Panzeria alashanica, 20 g of radix achyranthis bidentatae, 20 g of prepared fleece-flower root, 30 g of common macrocarpium fruit, 10 g of Mesona chinensis, 20 g of shizandra berry, 10 g of pseudo-ginseng powder and 10 g of prepared aconite root. The traditional Chinese medicine composition can be processed into decoctions or concentrated pills or concentrated capsules by a conventional method, and can be used for treating chronic uremia.

Description

Chinese medicine composition for the treatment of chronic uremia and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine composition for the treatment of chronic uremia and preparation method thereof.

Background technology

Chronic uremia is one of current disease of being thought incurable disease by medical circle, and Therapeutic Method can only be with hemodialysis, and periodic transfusions or kidney transplantation sustain life, and the height of its expense is that the patient is out of reach.Day by day increase the weight of in patient economy burden, unable dialysis, in blood transfusion or the situation of kidney transplantation, eventually because of organ hemorrhage, cardiac-cerebral ischemia, the five internal organs all damage, heart-yang collapse and extremely.How to find a kind of medicine for the treatment of chronic uremia, alleviate patient economy burden, reduce gradually dialysis and blood transfusion, final disengaging dialysis and blood transfusion, extending survival of patients phase and raising patients ' life quality is the large Gospel of one on medical history.

Summary of the invention

The object of the invention is to provide a kind of Chinese medicine composition that is used for the treatment of chronic uremia and preparation method thereof, can effectively treat chronic uremia, make it reduce gradually dialysis and blood transfusion, the final disengaging dialyses and blood transfusion, alleviate patient economy burden, extend the survival of patients phase and improve patients ' life quality.

For achieving the above object, the invention provides a kind of Chinese medicine composition that is used for the treatment of chronic uremia, raw material and the weight thereof of making its effective active ingredient are as follows:

Radix Angelicae Sinensis 10g, Radix Rehmanniae Preparata 20g, Radix Paeoniae Alba 20g, Rhizoma Chuanxiong 20g, Radix Astragali 30g, Caulis Bambusae In Taenia 10g, Herba Pogostemonis 10g, Rhizoma Pinelliae 10g, Cortex Magnoliae Officinalis 10g, Fructus Tsaoko 10g, Radix Et Rhizoma Rhei 20g, Semen Pharbitidis 10g, Pericarpium Citri Reticulatae 20g, raw oyster powder 30g, Endothelium Corneum Gigeriae Galli (parched) 20g, each 20g of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), Polyporus 10g, Rhizoma Alismatis 20g, Semen Plantaginis 20g, Radix Salviae Miltiorrhizae 20g, Hirudo 10g, Panzeria larata L. 20g, Radix Achyranthis Bidentatae 20g, Radix Polygoni Multiflori Preparata 20g, Fructus Corni 30g, Herba Epimedii 10g, Fructus Schisandrae Chinensis 20g, Radix Notoginseng powder 10g, Radix Aconiti Lateralis Preparata 10g.

For achieving the above object, the invention provides a kind of medicine for the treatment of chronic uremia, described medicine is made decoction or concentrated pill or concentrated capsule according to a conventional method by above-mentioned Chinese medicine composition.

Use the Chinese medicine for the treatment of chronic uremia provided by the invention, can effectively control chronic uremia, reduce gradually dialysis and blood transfusion, avoid kidney transplantation, final disengaging dialysis and blood transfusion are kept with a small amount of medicine, have improved Quality of Life and have extended the survival of patients phase.And in the situation that the toxic and side effects that follows the doctor's advice is little, no dependence.

The specific embodiment

The invention will be further described below in conjunction with embodiment.

The invention provides a kind of Chinese medicine composition for the treatment of chronic uremia, raw material and the weight thereof of making its effective active ingredient are as follows:

Radix Angelicae Sinensis 10g, Radix Rehmanniae Preparata 20g, Radix Paeoniae Alba 20g, Rhizoma Chuanxiong 20g, Radix Astragali 30g, Caulis Bambusae In Taenia 10g, Herba Pogostemonis 10g, Rhizoma Pinelliae 10g, Cortex Magnoliae Officinalis 10g, Fructus Tsaoko 10g, Radix Et Rhizoma Rhei 20g, Semen Pharbitidis 10g, Pericarpium Citri Reticulatae 20g, raw oyster powder 30g, Endothelium Corneum Gigeriae Galli (parched) 20g, each 20g of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), Polyporus 10g, Rhizoma Alismatis 20g, Semen Plantaginis 20g, Radix Salviae Miltiorrhizae 20g, Hirudo 10g, Panzeria larata L. 20g, Radix Achyranthis Bidentatae 20g, Radix Polygoni Multiflori Preparata 20g, Fructus Corni 30g, Herba Epimedii 10g, Fructus Schisandrae Chinensis 20g, Radix Notoginseng powder 10g, Radix Aconiti Lateralis Preparata 10g.

Above-mentioned medicine is take decoction as main, and one pair of every day, twice mixing of decocting taken at twice.Three months is a course for the treatment of, and take effect a general course for the treatment of, and two courses for the treatment of can be substantially controlled.Also above-mentioned Chinese medicine composition can be made according to a conventional method decoction or concentrated pill or concentrated capsule.

The clinical treatment report: this prescription is treated chronic uremia 42 examples altogether, male 26 examples, and female's 16 examples, wherein 14 years old-50 years old 25 examples, 51 years old-70 years old 17 examples exemplify model case 4 examples in 42 examples.

Case 1.

Certain female, 60 years old, calendar year 2001 JIUYUE suffer from that nephropathy lives that city's hospital diagnosis uses hormones for " chronic renal failure " (Uremic) and in conjunction with after dialysis and transfusing blood 1 year, because patient's financial difficulties can not be kept treatment, come to seek out of admiration for a famous person the traditional Chinese medical science, chemical examination after dialysis, serum creatinine 867umol/L, blood urea nitrogen 40mmol/L, the front chemical examination of dialysing afterwards in three days rises to serum creatinine 1070umol/L, blood urea nitrogen 47mmol/L, hemoglobin 70g/L.

Take above-mentioned formula dosage decoction treatment, and in conjunction with dialysis, after 100 days, the blood test creatinine drops to 496umol/L, blood urea nitrogen 31mmol/L, hemoglobin 90g/L.Dialysis is by subtracting into for 3 times 2 times weekly.Take above-mentioned formula decoction after 1 year, dialysis subtracts into 1 time weekly, and serum creatinine drops to 360umol/L, blood urea nitrogen 24mmol/L, and the patient is very confident, and complexion has ruddy gloss.Take above-mentioned formula dosage decoction after 2 years, deduct dialysis and blood transfusion, hormone also reduces to 15mg.Blood test creatinine 300umol/L, blood urea nitrogen 19mmol/L, hemoglobin 101g/L.Continue to take above-mentioned formula dosage decoction after 3 years, in October, 2005 is because really drinking the Chinese medicine that is fed up, propose the to have stopped oral Chinese medicine decoction of 3 years, and hormone is down to 10mg and is observed.Blood test creatinine 280umol/L, blood urea nitrogen 18.5mmol/L, hemoglobin 105g/L.Continuation is kept observation with the 10mg hormone, and quality of life near the normal person so far.

Case 2.

Certain man 54 years old, the peasant, spring in 2003 was lived certain county hospital because of nephropathy, after turn City Hospitals, after western medical treatment, the state of an illness can not be alleviated, creatinine 958umol/L, blood urea nitrogen 39mmol/L, hospital requires hemodialysis, and takes hormone 50mg/ day, patient's financial difficulties, access my institute's Chinese traditional treatment, after treating 6 months with above-mentioned formula agent amount, serum creatinine is down to 280umol/L, hematuria element oxygen 10mmol/L, assist to go down hormone with a small amount of our Chinese medicine afterwards, after 18 months, hormone reduces to 10mg, measures with this and keeps 5 years.

The Spring Festival in 2008 caught a cold, due to not in time treatment, make the nephropathy uremia recurrence of keeping 5 years, serum creatinine rises to 1500umol/L, after continuous dialysis 12 times, drop to 900umol/L, restart above-mentioned formula dosage treatment, dialysis is by reducing to for 3 times weekly 2 times weekly, reduce to after 3 months 1 time weekly, after reduce to again 10 days once, serum creatinine 900umol/L is down to 448,394,269,195umol/L gradually, blood urea nitrogen 11mmol/L, hemoglobin rises to 110g/L gradually by 45g/L, and is in high spirits, and sound is loud and clear.

The lunar New Year's Day in the Spring Festival in 2009, because never eat the patient of Carnis Sus domestica always, relatives advise, and have celebrated the New Year or the Spring Festival, and have some Carnis Sus domestica, result has been eaten the some braised pork with soy sauce and has been caused severe diarrhea, due to festivals or holidays in the Spring Festival, fail in time to treat, just live City Hospitals after 10 days and rescue, promptly all rescue measures proved ineffectual through hospital, and the first month of the lunar year 15, diarrheal dehydration was dead.

Case 3.

Certain female, 18 years old, student, in December, 2004 felt not quite the thing between last term, check to city hospital comprehensively and be " lupus erythematosus nephritis ", the western medical treatment of being in hospital, can not fully recover always, bad during fashion, in February, 2008 state of an illness in treating 3 years increases the weight of suddenly, develops into " uremia ", continues hospitalization after 10 months, serum creatinine 1090umol/L, blood urea nitrogen 40mmol/L, the dialysis of being compelled to do, beginning be 3 dialysis weekly, and in conjunction with blood transfusion, my the institute's treatment of coming out of admiration for a famous person on January 30th, 2009.Patient's complexion ash is dim, pale lips, and slippery and rapid pulse is strong, blood pressure 180/110Hmmg.Start above-mentioned Chinese medicine formula dosage through the court in conjunction with after dialysing 30 days, serum creatinine drops to 500umol/L, carbamide oxygen 28mmol/L, blood pressure 140/90Hmmg, take above-mentioned Chinese medicine formula dosage treatment 1 year and stop dialysis, serum creatinine drops to 340umol/L, carbamide oxygen 13mmol/L, blood pressure is normal, hemoglobin rises to 105g/L, and because this patient is single parent children, mother and daughter two people are very difficult, 50% expenses for medicine is only received by the court, after the Spring Festival in 2010, drug withdrawal automatically is through investigating stable disease, only take the 10mg hormone, quality of life such as ordinary person.

Case 4.

Certain man, 50 years old, Wulanchabu League of Inner Mongolia people from city, morbidity in 2007, the abdominal distention of breathing hard, dyspnea is diagnosed as chronic renal failure through living City Hospitals, Uremic merges hydrothorax, serum creatinine 1310umol/L, blood urea nitrogen 47.3mmol/L, blood uric acid 1194, carbon dioxide 10.8, take out hydrothorax through the City Hospitals hemodialysis, renal function index descends to some extent, treats after 3 years, blood creatinine 658/umol/L, blood urea nitrogen 24.8mmol/L, blood uric acid 464.But hydrothorax does not subtract always, dyspnea.Chinese traditional treatment is looked in JIUYUE in 2010 packet header of coming out of admiration for a famous person in 20th, enables above-mentioned formula dosage treatment through the court 1 year, and stops dialysis, hydrothorax goes down, and blood creatinine is down to 361umol/L, blood urea nitrogen 21mmol/L, stable disease is kept treatment with we so far, enjoys the quality of life near the normal person.

In sum, with above-mentioned formula agent amount treatment chronic uremia, can reduce gradually dialysis and blood transfusion, the final disengaging dialyses and blood transfusion, and can steadily reduce the hormone amount and disease does not rebound, and alleviate patient economy burden, fundamentally improve the state of an illness, improve Quality of Life and life courage, extend the survival of patients date.

Claims (2)

1. a Chinese medicine composition for the treatment of chronic uremia, is characterized in that, raw material and the weight thereof of making its active drug effective constituent are as follows:

Radix Angelicae Sinensis 10g, Radix Rehmanniae Preparata 20g, Radix Paeoniae Alba 20g, Rhizoma Chuanxiong 20g, Radix Astragali 30g, Caulis Bambusae In Taenia 10g, Herba Pogostemonis 10g, Rhizoma Pinelliae 10g, Cortex Magnoliae Officinalis 10g, Fructus Tsaoko 10g, Radix Et Rhizoma Rhei 20g,, Semen Pharbitidis 10g, Pericarpium Citri Reticulatae 20g, raw oyster powder 30g, Endothelium Corneum Gigeriae Galli (parched) 20g, each 20g of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), Polyporus 10g, Rhizoma Alismatis 20g, Semen Plantaginis 20g, Radix Salviae Miltiorrhizae 20g, Hirudo 10g, Panzeria larata L. 20g, Radix Achyranthis Bidentatae 20g, Radix Polygoni Multiflori Preparata 20g, Fructus Corni 30g, Herba Epimedii 10g, Fructus Schisandrae Chinensis 20g, Radix Notoginseng powder 10g, Radix Aconiti Lateralis Preparata 10g.

2. prepare the method for the Chinese medicine composition of the described treatment chronic uremia of claim 1: described medicine is made decoction, concentrated pill or concentrated capsule according to a conventional method by the described Chinese medicine composition of claim 1.