CN102471315B - 制备4-氨基丁-2-烯羟酸内酯的方法 - Google Patents
制备4-氨基丁-2-烯羟酸内酯的方法 Download PDFInfo
- Publication number
- CN102471315B CN102471315B CN201080035042.9A CN201080035042A CN102471315B CN 102471315 B CN102471315 B CN 102471315B CN 201080035042 A CN201080035042 A CN 201080035042A CN 102471315 B CN102471315 B CN 102471315B
- Authority
- CN
- China
- Prior art keywords
- base
- alkyl
- acid
- pyridin
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 0 CN(*)C(CO1)=CC1=O Chemical compound CN(*)C(CO1)=CC1=O 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/66—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09168068 | 2009-08-18 | ||
| EP09168068.6 | 2009-08-18 | ||
| US23587809P | 2009-08-21 | 2009-08-21 | |
| US61/235,878 | 2009-08-21 | ||
| US61/235878 | 2009-08-21 | ||
| PCT/EP2010/004800 WO2011020564A1 (de) | 2009-08-18 | 2010-08-05 | Neues verfahren zur herstellung von 4-aminobut-2-enoliden |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102471315A CN102471315A (zh) | 2012-05-23 |
| CN102471315B true CN102471315B (zh) | 2014-05-28 |
Family
ID=41226872
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201080035042.9A Active CN102471315B (zh) | 2009-08-18 | 2010-08-05 | 制备4-氨基丁-2-烯羟酸内酯的方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8314242B2 (enExample) |
| EP (1) | EP2467374B1 (enExample) |
| JP (1) | JP5671537B2 (enExample) |
| KR (1) | KR20120059555A (enExample) |
| CN (1) | CN102471315B (enExample) |
| BR (1) | BR112012003225A2 (enExample) |
| DK (1) | DK2467374T3 (enExample) |
| ES (1) | ES2421394T3 (enExample) |
| IL (1) | IL217460A0 (enExample) |
| IN (1) | IN2012DN01461A (enExample) |
| MX (1) | MX2012001727A (enExample) |
| TW (1) | TW201111370A (enExample) |
| WO (1) | WO2011020564A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113896679B (zh) * | 2021-11-18 | 2024-03-01 | 合肥利夫生物科技有限公司 | 一种吡咯吡啶激酶抑制剂关键中间体的合成方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007115644A1 (de) * | 2006-03-31 | 2007-10-18 | Bayer Cropscience Ag | Substituierte enaminocarbonylverbindungen |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH503722A (de) | 1969-05-28 | 1971-02-28 | Lonza Ag | Verfahren zur Herstellung von Tetronsäure |
| DE3311003A1 (de) | 1983-03-25 | 1984-09-27 | Bayer Ag, 5090 Leverkusen | Chromon- und thiochromonsubstituierte 1,4-dihydropyridinlactone, mehrere verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
| CH658056A5 (de) | 1984-02-09 | 1986-10-15 | Lonza Ag | Verfahren zur herstellung von tetronsaeure. |
| EP0539588A1 (en) | 1990-07-05 | 1993-05-05 | Nippon Soda Co., Ltd. | Amine derivative |
| US5252741A (en) * | 1990-08-10 | 1993-10-12 | Reilly Industries, Inc. | Processes for the synthesis of imines, aldehydes, and unsymmetrical secondary amines |
| EP2039678A1 (de) * | 2007-09-18 | 2009-03-25 | Bayer CropScience AG | Verfahren zum Herstellen von 4-Aminobut-2-enoliden |
| EP2042496A1 (de) * | 2007-09-18 | 2009-04-01 | Bayer CropScience AG | Verfahren zur Herstellung von 4-Aminobut-2-enoliden |
-
2010
- 2010-07-30 TW TW099125236A patent/TW201111370A/zh unknown
- 2010-08-05 KR KR1020127006802A patent/KR20120059555A/ko not_active Withdrawn
- 2010-08-05 JP JP2012525066A patent/JP5671537B2/ja active Active
- 2010-08-05 WO PCT/EP2010/004800 patent/WO2011020564A1/de not_active Ceased
- 2010-08-05 MX MX2012001727A patent/MX2012001727A/es active IP Right Grant
- 2010-08-05 BR BR112012003225A patent/BR112012003225A2/pt not_active Application Discontinuation
- 2010-08-05 ES ES10742759T patent/ES2421394T3/es active Active
- 2010-08-05 CN CN201080035042.9A patent/CN102471315B/zh active Active
- 2010-08-05 IN IN1461DEN2012 patent/IN2012DN01461A/en unknown
- 2010-08-05 EP EP10742759.3A patent/EP2467374B1/de active Active
- 2010-08-05 DK DK10742759.3T patent/DK2467374T3/da active
- 2010-08-17 US US12/858,031 patent/US8314242B2/en active Active
-
2012
- 2012-01-10 IL IL217460A patent/IL217460A0/en unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007115644A1 (de) * | 2006-03-31 | 2007-10-18 | Bayer Cropscience Ag | Substituierte enaminocarbonylverbindungen |
Also Published As
| Publication number | Publication date |
|---|---|
| TW201111370A (en) | 2011-04-01 |
| DK2467374T3 (da) | 2013-08-05 |
| EP2467374B1 (de) | 2013-05-01 |
| BR112012003225A2 (pt) | 2015-09-22 |
| EP2467374A1 (de) | 2012-06-27 |
| KR20120059555A (ko) | 2012-06-08 |
| MX2012001727A (es) | 2012-04-02 |
| US8314242B2 (en) | 2012-11-20 |
| ES2421394T3 (es) | 2013-09-02 |
| JP5671537B2 (ja) | 2015-02-18 |
| IN2012DN01461A (enExample) | 2015-06-05 |
| JP2013502385A (ja) | 2013-01-24 |
| WO2011020564A1 (de) | 2011-02-24 |
| IL217460A0 (en) | 2012-03-01 |
| US20110054182A1 (en) | 2011-03-03 |
| CN102471315A (zh) | 2012-05-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20151021 Address after: German Monheim Patentee after: BAYER INTELLECTUAL PROPERTY GmbH Address before: German Monheim Patentee before: Bayer Cropscience AG |
|
| CP03 | Change of name, title or address |
Address after: 50 Alfred Nobel Street, Monheim, Rhine, Germany 40789 Patentee after: BAYER INTELLECTUAL PROPERTY GmbH Address before: Germany Patentee before: BAYER INTELLECTUAL PROPERTY GmbH |
|
| CP03 | Change of name, title or address | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20240115 Address after: 50 Alfred Nobel Street, Monheim, Rhine, Germany 40789 Patentee after: BAYER CROPSCIENCE AG Address before: 50 Alfred Nobel Street, Monheim, Rhine, Germany 40789 Patentee before: BAYER INTELLECTUAL PROPERTY GmbH |
|
| TR01 | Transfer of patent right |