CN102451301A - Externally-used paste for treating psoriasis - Google Patents
Externally-used paste for treating psoriasis Download PDFInfo
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- CN102451301A CN102451301A CN2010105162235A CN201010516223A CN102451301A CN 102451301 A CN102451301 A CN 102451301A CN 2010105162235 A CN2010105162235 A CN 2010105162235A CN 201010516223 A CN201010516223 A CN 201010516223A CN 102451301 A CN102451301 A CN 102451301A
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- methotrexate
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- frost
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Abstract
The invention discloses externally-used paste for treating psoriasis, which comprises the following components: 20-40 g of purslane, 5-10 g of mints, 5-8 g of camphor, 10-15 g of grape seeds, 20-30 g of methotrexate cream, and 20-30 g of vaseline. The preparation method comprises the following steps: pulverizing mints, camphor, and grape seeds, sieving by a 200-mesh sieve, then adding methotrexate cream, well mixing; pulverizing fresh purslane to obtain thick liquid, adding the above components, then adding vaseline, well mixing to prepare paste. During treatment, the paste is applied to an affected part. The paste is only applied once a day, takes effect generally after three to four days, and takes obvious effect after two months when complete recovery is almost reached. During treatment, oral medicaments are simultaneously taken as well. Totally 245 patients are treated by the invention, and oral medicaments are combined for simultaneous administration generally during treatment; 202 patients are cured; the treatment is effective for 23 patients, and is ineffective for 20 patients; the total effective rate is up to 91.8%. The medicament of the invention has the advantages of good treatment effect, low cost, and the like.
Description
Technical field
The present invention relates to the psoriasic externally used paste of a kind of treatment.
Background technology
Psoriasis is a kind of common chronic dermatosis, it is characterized in that on erythema, occurring repeatedly the silvery white dry squama of multilamellar.Traditional Chinese medical science Gu is referred to as “ Bai Mange ", ancient doctor's nationality also is referred to as psoriasis.Doctor trained in Western medicine is called psoriasis (Psoriasis), is commonly called as psoriasis, it is characterized in that the pimple that occurs differing in size, and erythema, surface coverage silvery white squama, clear border, and good sending out stretched side and back in scalp, extremity.The male is more than the women.Winter in spring easy relapse or increase the weight of, and alleviate summer and autumn more.Psoriasic symptom: from the beginning of skin lesion red packet or brownish red point or maculopapule often, exsiccant squama is arranged, expansion forming the brownish red speckle gradually later on, clear border, and adjacent can merge mutually.Squama is silvery white, gradually thickening.When scratching, squama is broken end and flies one after another, exposes red smooth basal plane, is called the thin film phenomenon, and peelling off thin film has the big little petechial hemorrhage of syringe needle, and the scarlet surface of this film like has the situation of petechial hemorrhage to be called as this phenomenon now difficult to understand.Some patient's squama is not only thick but also hard, can hinder skin flexible, and especially joint etc. is located thick hard shell bits and is easy to break and makes skin generation breach and pain.
According to investigations, psoriatic sickness rate accounts for 0.1%～3% of world population, and yellow's sickness rate is 0.1%～0.3%, and the sickness rate white people of this disease in the crowd are apparently higher than the yellow, and black race takes second place.By 2007, China psoriatic reached 4,580,000 people.The investigation of USA in recent years, its sickness rate are 2.6%, and the patient reaches 600-700 ten thousand people, is higher than China far away.Because of the obstinate refractory of this disease, still classified as the important subject in department of dermatologry field, the world today, be one of whole world department of dermatologry keypoint control disease.In the national psoriasis control cooperation meeting of holding in recent years, the participant expert is consistent to be thought, and " it is the psoriatic direction of control that Chinese and Western medicine combines.Doctor trained in Western medicine anticarcinogen and hormone medicine have serious adverse, should avoid the use of as far as possible ".
Multiple antipsoriatics thing is arranged in the prior art, have for oral administrationly, external is also arranged, such as corticosteroid hormone ointment (frost), external has 20 years history.Strong imitate steroid hormone ointment (frost) external cleaning, instant effect, but drug withdrawal is prone to recurrence, the life-time service side effect increases, thus a lot of doctor's tendency need not, or only short-term, be interrupted use.
Summary of the invention
To above-mentioned prior art, the invention provides the psoriasic externally used paste of a kind of treatment, the present invention is a Chinese medicine and the combining of Western medicine, its instant effect has no side effect to skin.
The present invention realizes through following technical scheme:
The psoriasic externally used paste of a kind of treatment is composed of the following components: Herba Portulacae 20～40 grams, Herba Menthae 5～10 grams, Camphora 5～8 grams, Semen Vitis viniferae 10～15 grams, methotrexate frost 20～30 grams, vaseline 20～30 grams.
Preferably, be composed of the following components: Herba Portulacae 30 grams, Herba Menthae 8 grams, Camphora 6 grams, Semen Vitis viniferae 12 grams, methotrexate frost 25 grams, vaseline 25 grams.
Preferably, be composed of the following components: Herba Portulacae 25 grams, Herba Menthae 6 grams, Camphora 7 grams, Semen Vitis viniferae 11 grams, methotrexate frost 28 grams, vaseline 28 grams.
Preferably, be composed of the following components: Herba Portulacae 35 grams, Herba Menthae 7 grams, Camphora 8 grams, Semen Vitis viniferae 14 grams, methotrexate frost 22 grams, vaseline 22 grams.
A kind of method for preparing of treating psoriasic externally used paste: with Herba Menthae, Camphora, Semen Vitis viniferae porphyrize, cross 200 mesh sieves, add the methotrexate frost then, mixing; Then fresh Herba Portulacae is ground to thickness, adds in the aforementioned component, add vaseline again, mixing is processed unguentum.
During treatment, be coated on the affected part and get final product.Smeared once in one day and get final product, take effect after general three or four days, obviously take effect after two months, be close to recovery from illness.When treatment, preferably take oral drugs simultaneously, such as detoxicating pill, trimethoprim, VITAMIN C TABLET, Cyproheptadine etc., for oral administration and external application is treated simultaneously, and therapeutic effect is better.In addition, the patient is aspect diet, and warm article of answering hot raw meats such as diet tobacco and wine, fish and shrimp seafood, Carnis caprae seu ovis, Fructus Capsici to disperse, and for foods such as chicken and duck, Carnis Sus domestica, egg, river fish, milk, vegetable and fruit then should be taken in sufficient to guarantee nutrition.
The present invention is the combination of Chinese medicine and Western medicine, and wherein, the methotrexate frost can suppress the dna replication dna of affected part cell; Play the effect that stops the affected part enlarged areas; Herba Menthae, Camphora play heat-clearing and toxic substances removing, antipruriticly end dry effect, and Herba Portulacae can be discharged the affected part toxin; Reparation to skin has effect, and Semen Vitis viniferae is helpful to the recovery of skin.All medicines share, and can be used to treat psoriasis, and illing skin is not itched, and recover the normal colour of skin and feel.
The present invention treats 245 examples altogether, and the general oral drugs that combine are cured 202 examples in the time of treatment, effective 23 examples, and invalid 20 examples, total effective rate reaches 91.8%.Medicine of the present invention has that therapeutic effect is good, low cost and other advantages.
The specific embodiment
Below in conjunction with embodiment and case the present invention is further described.
The psoriasic externally used paste of embodiment 1 a kind of treatment of preparation
Prescription is: Herba Portulacae 30 grams, Herba Menthae 8 grams, Camphora 6 grams, Semen Vitis viniferae 12 grams, methotrexate frost 25 grams, vaseline 25 grams.
Method for preparing: with Herba Menthae, Camphora, Semen Vitis viniferae porphyrize, cross 200 mesh sieves, add the methotrexate frost then, mixing; Then fresh Herba Portulacae is ground to thickness, adds in the aforementioned component, add vaseline again, mixing is processed unguentum.
The psoriasic externally used paste of embodiment 2 a kind of treatments of preparation
Prescription is: Herba Portulacae 25 grams, Herba Menthae 6 grams, Camphora 7 grams, Semen Vitis viniferae 11 grams, methotrexate frost 28 grams, vaseline 28 grams.
Method for preparing: with Herba Menthae, Camphora, Semen Vitis viniferae porphyrize, cross 200 mesh sieves, add the methotrexate frost then, mixing; Then fresh Herba Portulacae is ground to thickness, adds in the aforementioned component, add vaseline again, mixing is processed unguentum.
The psoriasic externally used paste of embodiment 3 a kind of treatments of preparation
Prescription is: Herba Portulacae 35 grams, Herba Menthae 7 grams, Camphora 8 grams, Semen Vitis viniferae 14 grams, methotrexate frost 22 grams, vaseline 22 grams.
Method for preparing: with Herba Menthae, Camphora, Semen Vitis viniferae porphyrize, cross 200 mesh sieves, add the methotrexate frost then, mixing; Then fresh Herba Portulacae is ground to thickness, adds in the aforementioned component, add vaseline again, mixing is processed unguentum.
The psoriasic externally used paste of embodiment 4 a kind of treatments of preparation
Prescription is: Herba Portulacae 20 grams, Herba Menthae 5 grams, Camphora 8 grams, Semen Vitis viniferae 10 grams, methotrexate frost 30 grams, vaseline 20 grams.
Method for preparing: with Herba Menthae, Camphora, Semen Vitis viniferae porphyrize, cross 200 mesh sieves, add the methotrexate frost then, mixing; Then fresh Herba Portulacae is ground to thickness, adds in the aforementioned component, add vaseline again, mixing is processed unguentum.
The psoriasic externally used paste of embodiment 5 a kind of treatments of preparation
Prescription is: Herba Portulacae 40 grams, Herba Menthae 10 grams, Camphora 5 grams, Semen Vitis viniferae 15 grams, methotrexate frost 20 grams, vaseline 30 grams.
Method for preparing: with Herba Menthae, Camphora, Semen Vitis viniferae porphyrize, cross 200 mesh sieves, add the methotrexate frost then, mixing; Then fresh Herba Portulacae is ground to thickness, adds in the aforementioned component, add vaseline again, mixing is processed unguentum.
Case 1 patient appoints so-and-so, the man, and medial leg, the outside suffer from psoriasis, and skin is dark red, and pruritus is hard to bear, and the back erubescence that scratches has white scales to come off.During treatment, oral detoxicating pill, simultaneously external application unguentum of the present invention after 3 days, takes effect, and pruritus becomes little itching, after scratching, the white scales minimizing that comes off.After one month, little itching, after scratching, skin is flushing not, and no white scales comes off.After two months, do not itch, though illing skin has erythema, little with peripheral skin difference, feel is the same.
Case 2 patient Fangs, the man, there is island shape psoriasis at the back, and drying is dark red, and white scales is arranged, and pruritus is hard to bear, has difficulty in going to sleep every night.During treatment, oral trimethoprim, VITAMIN C TABLET and Cyproheptadine, the unguentum of the present invention of external application simultaneously after 3 days, takes effect, and pruritus becomes little itching, and after scratching, can go to sleep peacefully evening.After one month, little itching, after scratching, white scales comes off few.After two months, do not itch, illing skin is near normal, and feel is the same with normal skin.
Case 3 patient Mas, the man suffers from psoriasis in the form of sheets on the arm, and xerosis cutis is coarse, and a large amount of white scales are arranged, and red point is arranged after coming off.During treatment, oral trimethoprim, VITAMIN C TABLET and Cyproheptadine, the unguentum of the present invention of external application simultaneously after 3 days, takes effect, and pruritus becomes little itching.After one month, cure, illing skin and normal phase do not examine and do not see difference together, and feel is also identical.
Claims (5)
1. the psoriasic externally used paste of treatment is characterized in that, is composed of the following components: Herba Portulacae 20～40 grams, Herba Menthae 5～10 grams, Camphora 5～8 grams, Semen Vitis viniferae 10～15 grams, methotrexate frost 20～30 grams, vaseline 20～30 grams.
2. the psoriasic externally used paste of a kind of treatment according to claim 1 is characterized in that, is composed of the following components: Herba Portulacae 30 grams, Herba Menthae 8 grams, Camphora 6 grams, Semen Vitis viniferae 12 grams, methotrexate frost 25 grams, vaseline 25 grams.
3. the psoriasic externally used paste of a kind of treatment according to claim 1 is characterized in that, is composed of the following components: Herba Portulacae 25 grams, Herba Menthae 6 grams, Camphora 7 grams, Semen Vitis viniferae 11 grams, methotrexate frost 28 grams, vaseline 28 grams.
4. the psoriasic externally used paste of a kind of treatment according to claim 1 is characterized in that, is composed of the following components: Herba Portulacae 35 grams, Herba Menthae 7 grams, Camphora 8 grams, Semen Vitis viniferae 14 grams, methotrexate frost 22 grams, vaseline 22 grams.
5. the described a kind of method for preparing of treating psoriasic externally used paste of claim 1 is characterized in that: with Herba Menthae, Camphora, Semen Vitis viniferae porphyrize, cross 200 mesh sieves, add the methotrexate frost then, mixing; Then fresh Herba Portulacae is ground to thickness, adds in the aforementioned component, add vaseline again, mixing is processed unguentum.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105162235A CN102451301A (en) | 2010-10-22 | 2010-10-22 | Externally-used paste for treating psoriasis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105162235A CN102451301A (en) | 2010-10-22 | 2010-10-22 | Externally-used paste for treating psoriasis |
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| CN102451301A true CN102451301A (en) | 2012-05-16 |
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| CN2010105162235A Pending CN102451301A (en) | 2010-10-22 | 2010-10-22 | Externally-used paste for treating psoriasis |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013155584A1 (en) * | 2012-04-20 | 2013-10-24 | Biolab Sanus Farmacêutica Ltda. | Topical pharmaceutical composition, method for producing the topical pharmaceutical composition, use of the topical pharmaceutical composition and method for the topical treatment of psoriasis, atopic dermatitis or chronic eczema |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1260725A (en) * | 1997-05-09 | 2000-07-19 | 公众权益基金会德国癌症研究中心 | Conjugate composing folic acid antagonist and carrier |
| CN1437475A (en) * | 2000-05-12 | 2003-08-20 | 本特·克里斯特·奥尔森 | Combined cartilage and plant extract composition |
-
2010
- 2010-10-22 CN CN2010105162235A patent/CN102451301A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1260725A (en) * | 1997-05-09 | 2000-07-19 | 公众权益基金会德国癌症研究中心 | Conjugate composing folic acid antagonist and carrier |
| CN1437475A (en) * | 2000-05-12 | 2003-08-20 | 本特·克里斯特·奥尔森 | Combined cartilage and plant extract composition |
Non-Patent Citations (1)
| Title |
|---|
| 朱时飞等: "清热凉血药外用治疗寻常型银屑病的概况", 《中医药导报》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013155584A1 (en) * | 2012-04-20 | 2013-10-24 | Biolab Sanus Farmacêutica Ltda. | Topical pharmaceutical composition, method for producing the topical pharmaceutical composition, use of the topical pharmaceutical composition and method for the topical treatment of psoriasis, atopic dermatitis or chronic eczema |
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Application publication date: 20120516 |