CN102430132A - Sterilization type medical ultrasonic coupling agent - Google Patents

Sterilization type medical ultrasonic coupling agent Download PDF

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Publication number
CN102430132A
CN102430132A CN2011104155722A CN201110415572A CN102430132A CN 102430132 A CN102430132 A CN 102430132A CN 2011104155722 A CN2011104155722 A CN 2011104155722A CN 201110415572 A CN201110415572 A CN 201110415572A CN 102430132 A CN102430132 A CN 102430132A
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percent
coupling agent
triethanolamine
carboxymethyl cellulose
carbomer
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CN2011104155722A
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CN102430132B (en
Inventor
丛培银
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Weihai Xishikang Bio-Engineering Co., Ltd.
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WEIHAI XISHIKANG BIO-ENGINEERING Co Ltd
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Publication of CN102430132A publication Critical patent/CN102430132A/en
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Abstract

The invention relates to a sterilization type medical ultrasonic coupling agent, which is formed by mixing Carbomer and carboxymethyl cellulose serving as main raw materials, with glycerol, polyethylene glycol, triethanolamine, sodium hydroxide, tolamine, phenethyl alcohol and water. The coupling agent particularly consists of the following components in percentage by weight: 0.5 to 1 percent of Carbomer, 0.5 to 1 percent of carboxymethyl cellulose, 1 to 2 percent of glycerol, 1 to 2 percent of polyethylene glycol, 0.5 to 1 percent of triethanolamine, 0.3 to 0.6 percent of 20 percent sodium hydroxide, 0.3 to 0.6 percent of tolamine, 0.5 to 1 percent of phenethyl alcohol, and the balance of water. The sterilization type medical ultrasonic coupling agent has reasonable prescription, stable performance and convenience for use, has the function of disinfection and bacteriostasis, and is especially matched with medical ultrasonic examination. One coupling agent is used once for one person, so that the coupling agent is clean and sanitary, and is convenient for use.

Description

A kind of disinfection sterilizing type medical supersonic couplant
Technical field
The present invention relates to a kind of couplant, specifically a kind of disinfection sterilizing type medical supersonic couplant.
Background technology
At present, the ultrasonic coupling agent that hospital uses is common couplant, and it mainly is that carboxymethyl cellulose is dissolved in water and processes, and hyperacoustic transmission is had coupling, but do not have disinfecting and sterilizing functions.Be commonly the plastic tube dress preparation of the big packing of 250 grams.One pipe generally is used for 10-20 patients, has the chance of mutual cross infection." Regulations of sterilization management " the 6th requirement, the apparatus and the articles for use of all contacting skins of medical and health organization, mucosa must reach the sterilization requirement, to prevent and to reduce the chance of nosocomial infection of hospital.
Summary of the invention
Technical problem to be solved by this invention is the deficiency that overcomes above-mentioned prior art, provides a kind of composition reasonable, and stable performance, easy to use has the sterilization bacteria resistance function, and coupling effect is good, and resolution is high, the disinfection sterilizing type medical supersonic couplant of clear image.
The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of disinfection sterilizing type medical supersonic couplant, and it is a primary raw material with carbomer and carboxymethyl cellulose, adds glycerin, Polyethylene Glycol, triethanolamine, sodium hydroxide, chloro-4-toluenesulphonamide sodium, phenethanol and water and mixes; The concrete percentage by weight of forming is: carbomer 0.5-1%, carboxymethyl cellulose 0.5-1%, glycerin 1-2%; Polyethylene Glycol 1-2%; Triethanolamine 0.5-1%, concentration is 20% sodium hydroxide 0.3-0.6%, chloro-4-toluenesulphonamide sodium 0.3-0.6%; Phenethanol 0.5-1%, surplus is a water.
In the present invention prescription with carbomer and carboxymethyl cellulose as be coupled, thickening agent; The glycerin that adds has preserves moisture and lubrication; The Polyethylene Glycol tool is with thickening and lubrication; Triethanolamine and sodium hydroxide have the effect of the PH of adjusting, and chloro-4-toluenesulphonamide sodium has the sterilizing effect, and phenethanol has the sterilizing effect.Mentioned component is added in the purified water, heating, stirring, dissolving, swelling form the transparence gel.Discharge micro-bubble wherein, keep its transparence gel form.Last fill is a finished product.Through a large amount of evidences, product of the present invention has fast and the long-acting bactericidal sterilizing effect, and is harmless to human non-toxic, meets relevant each item standard-required.Against existing technologies, the present invention fills a prescription rationally, stable performance, easy to use, has the sterilization bacteria resistance function.Sterilization type medical ultrasonic coupling agent of the present invention can prop up the independent packaging preparation for the list of 15-20 grams, is specifically designed to cooperate the medical supersonic inspection to use, and a people once uses one, and clean health is easy to use.
The specific embodiment
Below in conjunction with embodiment the present invention is further specified.
A kind of disinfection sterilizing type medical supersonic couplant, it is a primary raw material with carbomer and carboxymethyl cellulose, adds glycerin, Polyethylene Glycol, triethanolamine, sodium hydroxide, chloro-4-toluenesulphonamide sodium, phenethanol and water and mixes; The concrete percentage by weight of forming is: carbomer 0.5-1%, carboxymethyl cellulose 0.5-1%, glycerin 1-2%; Polyethylene Glycol 1-2%; Triethanolamine 0.5-1%, concentration is 20% sodium hydroxide 0.3-0.6%, chloro-4-toluenesulphonamide sodium 0.3-0.6%; Phenethanol 0.5-1%, surplus is a water.
Carbomer has coupling and thickening power in the present invention's prescription; Carboxymethyl cellulose has coupling and thickening power, and glycerin has preserves moisture and lubrication, and the Polyethylene Glycol tool is with thickening and lubrication; Triethanolamine has the effect of the PH of adjusting; Sodium hydroxide has the effect of the PH of adjusting, and chloro-4-toluenesulphonamide sodium has the sterilizing effect, and phenethanol has the sterilizing effect.Mentioned component is added in the purified water, heating, stirring, dissolving, swelling form the transparence gel.Discharge micro-bubble wherein, keep its transparence gel form.Last fill is a finished product.Prove that through repetition test product of the present invention has fast and the long-acting bactericidal sterilizing effect, and is harmless to human non-toxic, meet relevant each item standard-required.Sterilization type medical ultrasonic coupling agent of the present invention can prop up the independent packaging preparation for the list of 15-20 grams, is specifically designed to cooperate the medical supersonic inspection to use, and a people once uses one, and clean health is easy to use.Have disinfecting and sterilizing functions, effectively prevent and reduce nosocomialtion, prevent and control the outburst of infectious disease and popular.
Embodiment 1: a kind of disinfection sterilizing type medical supersonic couplant, and it is mixed by carbomer, carboxymethyl cellulose, glycerin, Polyethylene Glycol, triethanolamine, sodium hydroxide, chloro-4-toluenesulphonamide sodium, phenethanol and water, specifically forms percentage by weight to be: carbomer 0.5%; Carboxymethyl cellulose 1%, glycerin 1%, PEG400 type 2%; Triethanolamine 0.5%, concentration are 20% sodium hydroxide 0.6%, chloro-4-toluenesulphonamide sodium 0.3%; Phenethanol 1%, surplus are purified water.
With mentioned component in proportion, add in the purified water, heating, stirring, dissolving, swelling form the transparence gel.Discharge micro-bubble wherein, keep its transparence gel form.The list that last fill is 15-20 grams props up the finished product of independent packaging preparation.Have quick and long-acting bactericidal sterilizing effect, harmless to human non-toxic, meet relevant each item standard-required.Be specifically designed to the inspection of cooperation medical supersonic and use, a people once uses one, and clean health is easy to use.
Embodiment 2: a kind of disinfection sterilizing type medical supersonic couplant, and it is mixed by carbomer, carboxymethyl cellulose, glycerin, Polyethylene Glycol, triethanolamine, sodium hydroxide, chloro-4-toluenesulphonamide sodium, phenethanol and water, specifically forms percentage by weight to be: carbomer 1%; Carboxymethyl cellulose 0.5%, glycerin 2%, PEG400 type 1%; Triethanolamine 1%, concentration are 20% sodium hydroxide 0.3%, chloro-4-toluenesulphonamide sodium 0.6%; Phenethanol 0.5%, surplus are purified water.
With mentioned component in proportion, add in the purified water, heating, stirring, dissolving, swelling form the transparence gel.Discharge micro-bubble wherein, keep its transparence gel form.The list that last fill is 15-20 grams props up the finished product of independent packaging preparation.Have quick and long-acting bactericidal sterilizing effect, harmless to human non-toxic, meet relevant each item standard-required.Be specifically designed to the inspection of cooperation medical supersonic and use, a people once uses one, and clean health is easy to use.
Embodiment 3: a kind of disinfection sterilizing type medical supersonic couplant, and it is mixed by carbomer, carboxymethyl cellulose, glycerin, Polyethylene Glycol, triethanolamine, sodium hydroxide, chloro-4-toluenesulphonamide sodium, phenethanol and water, specifically forms percentage by weight to be: carbomer 0.75%; Carboxymethyl cellulose 0.75%; Glycerin 1.5%, PEG400 type 1.5%, triethanolamine 0.75%; Concentration is 20% sodium hydroxide 0.45%; Chloro-4-toluenesulphonamide sodium 0.45%, phenethanol 0.75%, surplus is a purified water.
With mentioned component in proportion, add in the purified water, heating, stirring, dissolving, swelling form the transparence gel.Discharge micro-bubble wherein, keep its transparence gel form.The list that last fill is 15-20 grams props up the finished product of independent packaging preparation.Have quick and long-acting bactericidal sterilizing effect, harmless to human non-toxic, meet relevant each item standard-required.Be specifically designed to the inspection of cooperation medical supersonic and use, a people once uses one, and clean health is easy to use.

Claims (2)

1. disinfection sterilizing type medical supersonic couplant, it is characterized in that: it is a primary raw material with carbomer and carboxymethyl cellulose, adds glycerin, Polyethylene Glycol, triethanolamine, sodium hydroxide, chloro-4-toluenesulphonamide sodium, phenethanol and water and mixes; The concrete percentage by weight of forming is: carbomer 0.5-1%, carboxymethyl cellulose 0.5-1%, glycerin 1-2%; Polyethylene Glycol 1-2%; Triethanolamine 0.5-1%, concentration is 20% sodium hydroxide 0.3-0.6%, chloro-4-toluenesulphonamide sodium 0.3-0.6%; Phenethanol 0.5-1%, surplus is a water.
2. disinfection sterilizing type medical supersonic couplant according to claim 1 is characterized in that: it is specifically formed percentage by weight and is: carbomer 0.75%, carboxymethyl cellulose 0.75%; Glycerin 1.5%, PEG400 type 1.5%, triethanolamine 0.75%; Concentration is 20% sodium hydroxide 0.45%; Chloro-4-toluenesulphonamide sodium 0.45%, phenethanol 0.75%, surplus is a purified water.
CN 201110415572 2011-12-14 2011-12-14 Sterilization type medical ultrasonic coupling agent Active CN102430132B (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105435249A (en) * 2015-12-17 2016-03-30 秦志浩 Disinfecting and bacterium killing type medical ultrasonic coupling agent and preparation method thereof
CN106237348A (en) * 2016-08-18 2016-12-21 南京巨鲨显示科技有限公司 A kind of medical ultrasonic coupling agent and preparation method thereof
CN106632904A (en) * 2016-12-19 2017-05-10 钦州市钦南区科学技术情报研究所 Ultrasonic coupling medium material and preparation method thereof
CN107496942A (en) * 2017-09-20 2017-12-22 贺海霞 A kind of medical disinfecting type ultrasonic coupling agent and preparation method thereof
CN113786381A (en) * 2021-11-02 2021-12-14 云南白药集团健康产品有限公司 Gel and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1062468A (en) * 1990-12-21 1992-07-08 沈阳市新北制药厂 A kind of production method of ultrasonic coupling agent
CN101249268A (en) * 2008-03-20 2008-08-27 中山一枝生物技术有限公司 Disinfection sterilizing type medical supersonic couplant and method of preparing the same
CN101648026A (en) * 2009-07-21 2010-02-17 戴新春 Sterilizing type medical ultrasonic coupling agent and preparation method thereof
CN102218149A (en) * 2010-04-13 2011-10-19 舒朝锋 Medical ultrasonic couplant capable of disinfection and sterilization and preparation technology thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1062468A (en) * 1990-12-21 1992-07-08 沈阳市新北制药厂 A kind of production method of ultrasonic coupling agent
CN101249268A (en) * 2008-03-20 2008-08-27 中山一枝生物技术有限公司 Disinfection sterilizing type medical supersonic couplant and method of preparing the same
CN101648026A (en) * 2009-07-21 2010-02-17 戴新春 Sterilizing type medical ultrasonic coupling agent and preparation method thereof
CN102218149A (en) * 2010-04-13 2011-10-19 舒朝锋 Medical ultrasonic couplant capable of disinfection and sterilization and preparation technology thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
苏志立: "《新型B超耦合剂处方及工艺改进》", 《新型B超耦合剂处方及工艺改进》, vol. 17, no. 2, 31 December 2005 (2005-12-31) *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105435249A (en) * 2015-12-17 2016-03-30 秦志浩 Disinfecting and bacterium killing type medical ultrasonic coupling agent and preparation method thereof
CN106237348A (en) * 2016-08-18 2016-12-21 南京巨鲨显示科技有限公司 A kind of medical ultrasonic coupling agent and preparation method thereof
CN106632904A (en) * 2016-12-19 2017-05-10 钦州市钦南区科学技术情报研究所 Ultrasonic coupling medium material and preparation method thereof
CN107496942A (en) * 2017-09-20 2017-12-22 贺海霞 A kind of medical disinfecting type ultrasonic coupling agent and preparation method thereof
CN113786381A (en) * 2021-11-02 2021-12-14 云南白药集团健康产品有限公司 Gel and preparation method thereof

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Patentee before: Cong Peiyin