CN102430064A - Composition for tonifying primordial qi and removing meridian obstruction and regulating blood and preparation method thereof - Google Patents

Composition for tonifying primordial qi and removing meridian obstruction and regulating blood and preparation method thereof Download PDF

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Publication number
CN102430064A
CN102430064A CN2011103970383A CN201110397038A CN102430064A CN 102430064 A CN102430064 A CN 102430064A CN 2011103970383 A CN2011103970383 A CN 2011103970383A CN 201110397038 A CN201110397038 A CN 201110397038A CN 102430064 A CN102430064 A CN 102430064A
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parts
fructus
radix
preparation
composition
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CN102430064B (en
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苏朝品
叶雁波
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Zhangjiagang Tianyi Traditional Medicine Research Institute Co Ltd
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Zhangjiagang Tianyi Traditional Medicine Research Institute Co Ltd
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Abstract

The invention discloses a composition for tonifying primordial qi and removing meridian obstruction and regulating blood and a preparation method thereof. The composition is a preparation prepared from the following raw materials in part by weight: 1 to 60 parts of grape seed, 10 to 200 parts of apple, 5 to 80 parts of lingonberry, 10 to 200 parts of pine needle leaf, 5 to 60 parts of lemon, 20 to 80 parts of hawthorn fruit, 5 to 50 parts of root of red-rooted salvia, 5 to 50 parts of mulberry fruit, 10 to 50 parts of Chinese wolfberry, 10 to 50 parts of Korean ginseng, 10 to 50 parts of integripetal rhodiola herb, 50 to 500 parts of sticky rice bran, 1 to 100 parts of medicinal cyathula root, 1 to 50 parts of epimedium herb, 1 to 100 parts of scindapsus aureus, 1 to 200 parts of arginine, 1 to 200 parts of ornithine,1 to 10 parts of zinc gluconate, 1 to 10 parts of ferrous gluconate and 1 to 50 parts of cordyceps sinensis. The composition has high bioavailability, is easy to digest and absorb, does not have pessimal stimulation reaction to a gastrointestinal tract, can furthest exert the effect of proanthocyanidin extracted from different plants and plant seeds, and can effectively and quickly tonify primordial qi.

Description

A kind ofly be used for invigorating primordial QI, the composition and method of making the same of the treating blood disorders of promoting blood circulation
Technical field
the present invention relates to a kind ofly to be used for invigorating primordial QI, the composition and method of making the same of the treating blood disorders of promoting blood circulation.
Background technology
vigour is determining the whole of life.All existing the insufficiency of primordial QI even the day after tomorrow to cause most of people especially women saps one's vitality.People's vigour is inadequate, just can not produce enough antibody or immunity and go Fighting Disease, and last vigour exhausts just can be dead.Therefore, additional vigour is very important.According to the traditional Chinese medical science " void then auxilliary it; sthenia syndrome requiring purgation; heat then cold it; cold then heat " principle, insufficiency of primordial QI and even big wound will according to individual body constitution and disease from QI invigorating empty (deficiency of vital energy person), the void of enriching blood (blood deficiency person), nourishing YIN empty (deficiency of YIN person), empty (yang deficiency person) four aspects of YANG invigorating nourish, core wants tonify deficiency to set upright exactly.Yet, so far, very effective quick invigorating primordial QI product is not arranged also.
Summary of the invention
technical problem to be solved by this invention is the deficiency of clothes prior art, provides a kind of and is used for invigorating primordial QI, the compositions of the treating blood disorders of promoting blood circulation.
the present invention also will provide a kind of above-mentioned preparation of compositions method simultaneously.
for solving above technical problem, a kind of technical scheme that the present invention takes is: a kind ofly be used for invigorating primordial QI, the compositions of the treating blood disorders of promoting blood circulation, it is the preparation that is prepared from following materials of weight proportions: 1~60 part of Semen Vitis viniferae, 10~200 parts of Fructus Mali pumilaes; 5~80 parts of Pericarpium Citri tangerinaes, 10~200 parts of pine needles, 5~60 parts in Fructus Citri Limoniae, 20~80 parts of Fructus Crataegis; 5~50 parts of Radix Salviae Miltiorrhizae, 5~50 parts in Fructus Mori, 10~50 parts of Fructus Lyciis, 10~50 parts of Korean Ginseng; 10~50 parts of Radix Rhodiolaes, 50~500 parts of Oryza glutinosa brans, 1~100 part of Radix Cyathulae, 1~50 part of Herba Epimedii; 1~100 part of Scindapsus aureus, 1~200 part of arginine, 1~200 part of ornithine; 1~10 part of zinc gluconate, 1~10 part of Ferrous gluconate, 1~50 part of Cordyceps powder.
According to further embodiment of the present invention, said compositions preferably is prepared from following materials of weight proportions : 10~30 parts of Semen Vitis viniferae, 50~100 parts of Fructus Mali pumilaes, 10~40 parts of Pericarpium Citri tangerinaes, 50~100 parts of pine needles; 10~60 parts in Fructus Citri Limoniae, 20~60 parts of Fructus Crataegis, 8~30 parts of Radix Salviae Miltiorrhizae, 5~25 parts in Fructus Mori; 10~30 parts of Fructus Lyciis, 10~20 parts of Korean Ginseng, 10~50 parts of Radix Rhodiolaes, 50~200 parts of Oryza glutinosa brans; 5~30 parts of Radix Cyathulaes, 3~20 parts of Herba Epimedii, 5~60 parts of Scindapsus aureus, 10~100 parts of arginine; 10~100 parts of ornithines, 2~8 parts of zinc gluconate, 2~8 parts of Ferrous gluconate, 5~25 parts of Cordyceps powders.
The another technical scheme that the present invention takes is: a kind of above-mentioned preparation of compositions method, it comprises the steps:
(1), in proportion take by weighing Semen Vitis viniferae, fresh apple, Pericarpium Citri tangerinae, Fructus Citri Limoniae, Fructus Mori, Fructus Lycii and Fructus Crataegi are pulverized; The water that adds 20~80 times, stirring obtains aqueous dispersions, at room temperature concentrates with the membrance concentration system; Film selects the control molecular weight below 10,000, to the concentrated solution volume be 5%~10% of aqueous dispersions volume, adopt spray drying method to make granule; Smaller or equal to 3%, be defined as component (a) in vacuum drying to moisture below 65 ℃, for use;
(2), in proportion take by weighing Radix Salviae Miltiorrhizae, Radix Rhodiolae, pine needle, Radix Cyathulae, Scindapsus aureus, Herba Epimedii, Oryza glutinosa health and Korean Ginseng, be ground into granule, put in the ultrasonic extraction jar; The water that adds 15~40 times, ultrasonic extraction 1~2 hour, centrifugalize also keeps medicinal liquid; Medicinal liquid is become syrupy shape at 50 ℃~70 ℃ following vacuum concentration, change the vacuum drying oven drying over to, the control temperature is dried to moisture smaller or equal to 3% below 70 ℃; Be defined as component (b), for use;
(3), Cordyceps powder was toasted one hour the back powder of beating of cooling in 100 ℃~150 ℃ thermostatic drying chamber; With wearing into fine powder after zinc gluconate, Ferrous gluconate, arginine and the ornithine sterilization, with eastern worm summer grass meal mix homogeneously, be defined as component (c), subsequent use;
(4), mix with the component (a) and (b) and (c), add adjuvant and be mixed with preparation.
according to the present invention, described preparation can be oral liquid, capsule or powder etc.
Because the utilization of technique scheme, the present invention compared with prior art has following advantage:
In the present invention prescription; The apple polyphenol that contains in the extract of Fructus Mali pumilae has enhancing muscular strength, reduces interior fat, keeps breathing smooth and easy (being included in responsive season); Thereby reduce melanic formation skin whitening, help skin to prevent functions such as ultraviolet; Radix Rhodiolae extract has anti-aging effects, oxygen lack resistant function, anti-pessimal stimulation effect, to body dual regulation, antifatigue effect, the effect of inhibition blood sugar increasing, to the influence of learning and memory.The procyanidin that Semen Vitis viniferae extracts (OPC), the free radical scavenger of imitating the most by force that is so far to be found has very strong activity in vivo, strengthens the blood vessel wall resistance; Reduce capillary fragility, keep the suitable permeability of blood capillary, bruise is had mitigation, strengthen the function of blood capillary, vein, tremulous pulse; Alleviate the seriousness of athletic injury; Prevention is also alleviated varicosis; Alleviate edema and shank swelling; Treat chronic venous afunction; Reduce the initiation potential of diabetes; Improve the pliability of blood rbc film; Strengthen skin elasticity and soft and smooth property; The prevention sunray is to the radiation damage of skin; Irritated aspect: very effective to pollinosis (pollen hypersensitivity).
Application of TCM five colors of the present invention are joined five fortune; The five internal organs theory is organized prescription; The fever and chills and warm and cool property of medicine according to each different components has added adjuvant Testa oryzae extract simultaneously, Korean Ginseng reaches a coordinative role, has increased the bioavailability of these different procyanidins effectively, makes whole Fang Yi digest and assimilate; Gastrointestinal tract is not had bad IR, the effect of the procyanidin that from different plants and plant seed, extracts is brought into play to greatest extent.
The specific embodiment
are respectively the fruit of correspondence or the fruit of plant as the Semen Vitis viniferae in the raw material of pharmaceutical composition of the present invention, fresh apple, Pericarpium Citri tangerinae, Fructus Citri Limoniae, Fructus Mori, Fructus Lycii; Radix Salviae Miltiorrhizae in the raw material, Radix Rhodiolae, pine needle, Korean Ginseng, Fructus Crataegi, celestial being's spleen, Radix Cyathulae, Scindapsus aureus, Cordyceps powder are the medical material of commercially available acquisition; The Oryza glutinosa bran is shell or the skin that the Oryza glutinosa from Oryza glutinosa comes off, can adopt conventional separate preparation or buy obtain; Arginine, ornithine, zinc gluconate or Ferrous gluconate are the commercial goods.
further describe the present invention below in conjunction with concrete embodiment and accompanying drawing, but the invention is not restricted to these embodiment.
Embodiment 1
according to present embodiment be used for invigorating primordial QI, the compositions of the treating blood disorders of promoting blood circulation, its composition of raw materials is following: 20 parts of Semen Vitis viniferae, 70 parts of Fructus Mali pumilaes, 20 parts of Pericarpium Citri tangerinaes, 60 parts of pine needles, 35 parts in Fructus Citri Limoniae; 30 parts of Fructus Crataegis, 8 parts of Radix Salviae Miltiorrhizae, 10 parts in Fructus Mori, 20 parts of Fructus Lyciis, 15 parts of Korean Ginseng; 30 parts of Radix Rhodiolaes, 73 parts of Oryza glutinosa brans, 15 parts of Radix Cyathulaes, 5 parts of Herba Epimedii, 12 parts of Scindapsus aureus; 15 parts of arginine, 40 parts of ornithines, 5 parts of zinc gluconate, 6 parts of Ferrous gluconate, 11 parts of Cordyceps powders.
The method for preparing of above-mentioned composition is following:
(1), in proportion take by weighing Semen Vitis viniferae, fresh apple, Pericarpium Citri tangerinae, Fructus Citri Limoniae, Fructus Mori, Fructus Lycii and Fructus Crataegi are pulverized; The water that adds 20~30 times, stirring obtains aqueous dispersions, at room temperature concentrates with the membrance concentration system; Film selects the control molecular weight below 10,000, to the concentrated solution volume be about 5% of aqueous dispersions volume, adopt spray drying method to make granule; Smaller or equal to 3%, be defined as component (a) in vacuum drying to moisture below 65 ℃, for use;
(2), in proportion take by weighing Radix Salviae Miltiorrhizae, Radix Rhodiolae, pine needle, Radix Cyathulae, Scindapsus aureus, Herba Epimedii, Oryza glutinosa health and Korean Ginseng, be ground into granule, put in the ultrasonic extraction jar; The water that adds about 20 times, ultrasonic extraction 1~2 hour, centrifugalize also keeps medicinal liquid; Medicinal liquid is become syrupy shape at 50 ℃~70 ℃ following vacuum concentration, change the vacuum drying oven drying over to, the control temperature is dried to moisture smaller or equal to 3% below 70 ℃; Be defined as component (b), for use;
(3), Cordyceps powder was toasted one hour the back powder of beating of cooling in 100 ℃~150 ℃ thermostatic drying chamber; With wearing into fine powder after zinc gluconate, Ferrous gluconate, arginine and the ornithine sterilization, with eastern worm summer grass meal mix homogeneously, be defined as component (c), subsequent use;
(4), mix with the component (a) and (b) and (c), add adjuvant, be mixed with capsule according to conventional technology of preparing.
Embodiment 2
according to present embodiment be used for invigorating primordial QI, the compositions of the treating blood disorders of promoting blood circulation, its composition of raw materials is following: 2 parts of Semen Vitis viniferae, 140 parts of Fructus Mali pumilaes, 15 parts of Pericarpium Citri tangerinaes, 71 parts of pine needles, 35 parts in Fructus Citri Limoniae; 30 parts of Fructus Crataegis, 5 parts of Radix Salviae Miltiorrhizae, 20 parts in Fructus Mori, 15 parts of Fructus Lyciis, 25 parts of Korean Ginseng; 15 parts of Radix Rhodiolaes, 70 parts of Oryza glutinosa brans, 15 parts of Radix Cyathulaes, 5 parts of Herba Epimedii, 12 parts of Scindapsus aureus; 5 parts of arginine, 5 parts of ornithines, 5 parts of zinc gluconate, 5 parts of Ferrous gluconate, 5 parts of Cordyceps powders.
said preparation of compositions method is with embodiment 1.
Embodiment 3
according to present embodiment be used for invigorating primordial QI, the compositions of the treating blood disorders of promoting blood circulation, its composition of raw materials is following: 50 parts of Semen Vitis viniferae, 60 parts of Fructus Mali pumilaes, 15 parts of Pericarpium Citri tangerinaes, 71 parts of pine needles, 35 parts in Fructus Citri Limoniae; 30 parts of Fructus Crataegis, 5 parts of Radix Salviae Miltiorrhizae, 20 parts in Fructus Mori, 15 parts of Fructus Lyciis, 25 parts of Korean Ginseng; 25 parts of Radix Rhodiolaes, 64 parts of Oryza glutinosa brans, 5 parts of Radix Cyathulaes, 5 parts of Herba Epimedii, 50 parts of Scindapsus aureus; 5 parts of arginine, 5 parts of ornithines, 5 parts of zinc gluconate, 5 parts of Ferrous gluconate, 5 parts of Cordyceps powders.
said preparation of compositions method is with embodiment 1.
The capsule of embodiment 1-3, called after " complement promote blood circulation treating blood disorders " capsule, every 0.5g, the content of compositions is 80% in every capsules.
are found 50 elder's long-term observation of 50 ~ 88 years old through the clinical practice in 4 years by a definite date, and prescription of the present invention has the effect of completing the kidney invigorating essence and gate of vitality's vigour fast, and allaying tiredness regains one's strength and vigor rapidly.Men and women's sexual function is left early, and hyposexuality has specially good effect.Have the silt of invigorating blood circulation, dispel simultaneously, enrich blood, vessel softening and the elasticity and the vigor that recover blood vessel wall improve the microcirculatory effect of blood capillary, thereby can directly eliminate the senilism morbid state that causes owing to excessively physical overdraw, physical strength reinforcing and vigor, premature senescence resistance.Simultaneously can directly eliminate the various subhealth state Signs that cause owing to circulation of blood disorder, diabetes are had good auxiliary treatment effect, can significantly improve skin gloss simultaneously, eliminate the skin of face mottle and whole skin is bleached with ruddy.Typical case is following:
case 1: Su Huifang, the woman, 45 years old, fear of cold was afraid of cold, and ridge is afraid of cold especially, the pale no color of face, face has more freckle, and two hands chi pulses are heavy, and are trickle; A little less than closed on a left side, little profound, right pass was heavy profound, and MBV is few and slow, and some months just comes once sometimes.Take complement and promote blood circulation treating blood disorders capsule (3 * 500mg, every day sooner or later respectively once) one and a half months official holiday recovery normally, the complexion gain color.Freckle obviously tails off on the face, and the back of the body feels warm after two months, and it is warm that the trick in winter is also felt, vaginal dryness phenomenon for many years also disappears, and muscle power becomes plentifully, indefatigability.Palm arteries and veins: two hands chi pulses have been appeared again stronger, and left and right sides GUAN-pulse is evenly fluent strong.
case 2: Zhang Jian, the man, 42 years old, the spinal column dish was outstanding, and complexion is gloomy, two hands CHI-pulse being weak, right GUAN-pulse soft-weak pulse, Zuo Guanhong is real.The readme male sexuality is useless to have 3 years, and lumbago can not be sat too of a specified duration at ordinary times.Take complement treating blood disorders capsule (3 * 500mg, every day, sooner or later each the was once) one and a half months of promoting blood circulation, the complexion gain color, Lycoperdon polymorphum Vitt disappears, and it is normal that male sexuality recovers, and waist also becomes effectively, indefatigability, but the spinal column dish is given prominence to and is not disappeared.Palm arteries and veins: two hands chi pulses are appeared again, right close moderate pulse and spare, Zuo Guanshi but be not very big vast.
case 3: Chen Longchang, the man, 63 years old, suffer from coronary heart disease, arrhythmia, the shank vein has lighter song to rise, and has many blood capillaries to silt up around the sole, and complexion is gloomy.Palm arteries and veins: two hands chi deep-thready pulses are puckery, and left CUN-pulse is puckery short, closes soft pulse, and right pass is heavy and strong.Take the complement treating blood disorders capsule (3 * 500mg that promotes blood circulation; Every day, sooner or later each was once) two first quarter moons, it is bright that complexion becomes, the disappearance of rising of shank vein song; Blood capillary silts the most of disappearance of red filament up around the sole; The arrhythmia phenomenon disappears, and angiogram shows that the cardiovascular tremulous pulse is smooth fluent, conscious energetic.Palm arteries and veins: two hands chi pulses have been appeared again but heavy thin partially, and left CUN-pulse is slow and strong.
As stated, we are illustrated according to aim of the present invention fully , but the present invention is not limited to the foregoing description and implementation method.The practitioner of correlative technology field can carry out different variations and implement the foregoing description only being explanation technical conceive of the present invention and characteristics in the scope of technological thought permission of the present invention; Its purpose is to let the personage who is familiar with this technology can understand content of the present invention and enforcement according to this, can not limit protection scope of the present invention with this.All equivalences that spirit is done according to the present invention change or modify, and all should be encompassed within protection scope of the present invention

Claims (4)

  1. One kind be used for invigorating primordial QI, the compositions of the treating blood disorders of promoting blood circulation, it is characterized in that: it is the preparation that is prepared from following materials of weight proportions: 1~60 part of Semen Vitis viniferae, 10~200 parts of Fructus Mali pumilaes, 5~80 parts of Pericarpium Citri tangerinaes, 10~200 parts of pine needles; 5~60 parts in Fructus Citri Limoniae, 20~80 parts of Fructus Crataegis, 5~50 parts of Radix Salviae Miltiorrhizae, 5~50 parts in Fructus Mori; 10~50 parts of Fructus Lyciis, 10~50 parts of Korean Ginseng, 10~50 parts of Radix Rhodiolaes, 50~500 parts of Oryza glutinosa brans; 1~100 part of Radix Cyathulae, 1~50 part of Herba Epimedii, 1~100 part of Scindapsus aureus, 1~200 part of arginine; 1~200 part of ornithine, 1~10 part of zinc gluconate, 1~10 part of Ferrous gluconate, 1~50 part of Cordyceps powder.
  2. 2. compositions according to claim 1 is characterized in that: it is the preparation that is prepared from following materials of weight proportions: 10~30 parts of Semen Vitis viniferae, 50~100 parts of Fructus Mali pumilaes, 10~40 parts of Pericarpium Citri tangerinaes, 50~100 parts of pine needles; 10~60 parts in Fructus Citri Limoniae, 20~60 parts of Fructus Crataegis, 8~30 parts of Radix Salviae Miltiorrhizae, 5~25 parts in Fructus Mori; 10~30 parts of Fructus Lyciis, 10~20 parts of Korean Ginseng, 10~50 parts of Radix Rhodiolaes, 50~200 parts of Oryza glutinosa brans; 5~30 parts of Radix Cyathulaes, 3~20 parts of Herba Epimedii, 5~60 parts of Scindapsus aureus, 10~100 parts of arginine; 10~100 parts of ornithines, 2~8 parts of zinc gluconate, 2~8 parts of Ferrous gluconate, 5~25 parts of Cordyceps powders.
  3. 3. claim 1 or 2 described preparation of compositions methods is characterized in that: comprise the steps:
    (1), in proportion take by weighing Semen Vitis viniferae, fresh apple, Pericarpium Citri tangerinae, Fructus Citri Limoniae, Fructus Mori, Fructus Lycii and Fructus Crataegi are pulverized; The water that adds 20~80 times, stirring obtains aqueous dispersions, at room temperature concentrates with the membrance concentration system; Film selects the control molecular weight below 10,000, to the concentrated solution volume be 5%~10% of aqueous dispersions volume, adopt spray drying method to make granule; Smaller or equal to 3%, be defined as component (a) in vacuum drying to moisture below 65 ℃, for use;
    (2), in proportion take by weighing Radix Salviae Miltiorrhizae, Radix Rhodiolae, pine needle, Radix Cyathulae, Scindapsus aureus, Herba Epimedii, Oryza glutinosa health and Korean Ginseng, be ground into granule, put in the ultrasonic extraction jar; The water that adds 15~40 times, ultrasonic extraction 1~2 hour, centrifugalize also keeps medicinal liquid; Medicinal liquid is become syrupy shape at 50 ℃~70 ℃ following vacuum concentration, change the vacuum drying oven drying over to, the control temperature is dried to moisture smaller or equal to 3% below 70 ℃; Be defined as component (b), for use;
    (3), Cordyceps powder was toasted one hour the back powder of beating of cooling in 100 ℃~150 ℃ thermostatic drying chamber; With wearing into fine powder after zinc gluconate, Ferrous gluconate, arginine and the ornithine sterilization, with eastern worm summer grass meal mix homogeneously, be defined as component (c), subsequent use;
    (4), mix, add adjuvant and be mixed with preparation with the component (a) and (b) and (c).
  4. 4. method for preparing according to claim 3 is characterized in that: described preparation is oral liquid, capsule or powder.
CN 201110397038 2011-12-05 2011-12-05 Composition for tonifying primordial qi and removing meridian obstruction and regulating blood and preparation method thereof Expired - Fee Related CN102430064B (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103494133A (en) * 2013-08-23 2014-01-08 朱奕 Antifatigue health-care ginseng oral liquid and preparation method thereof
CN103564572A (en) * 2013-11-22 2014-02-12 威海环翠楼红参科技有限公司 Preparation method of Korean red ginseng soup
JP2017008002A (en) * 2015-06-25 2017-01-12 株式会社東洋新薬 Anti-fatigue agent
CN108094815A (en) * 2018-01-04 2018-06-01 中美御康生物科技(北京)有限公司 It enriches blood collagen solid beverage
JP2019194246A (en) * 2019-07-11 2019-11-07 株式会社東洋新薬 Anti-fatigue agent

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102028895A (en) * 2010-12-09 2011-04-27 张家港天乙传统医药研究院有限公司 Medicinal composition with antioxidant activity and blood vessel and blood cleaning antioxidant and/or protective agent

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102028895A (en) * 2010-12-09 2011-04-27 张家港天乙传统医药研究院有限公司 Medicinal composition with antioxidant activity and blood vessel and blood cleaning antioxidant and/or protective agent

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103494133A (en) * 2013-08-23 2014-01-08 朱奕 Antifatigue health-care ginseng oral liquid and preparation method thereof
CN103494133B (en) * 2013-08-23 2015-07-15 朱奕 Antifatigue health-care ginseng oral liquid and preparation method thereof
CN103564572A (en) * 2013-11-22 2014-02-12 威海环翠楼红参科技有限公司 Preparation method of Korean red ginseng soup
JP2017008002A (en) * 2015-06-25 2017-01-12 株式会社東洋新薬 Anti-fatigue agent
CN108094815A (en) * 2018-01-04 2018-06-01 中美御康生物科技(北京)有限公司 It enriches blood collagen solid beverage
JP2019194246A (en) * 2019-07-11 2019-11-07 株式会社東洋新薬 Anti-fatigue agent

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