CN102424126B - Standard substance vacuum subpackaging device and method for hematology analyzer - Google Patents
Standard substance vacuum subpackaging device and method for hematology analyzer Download PDFInfo
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- CN102424126B CN102424126B CN 201110243634 CN201110243634A CN102424126B CN 102424126 B CN102424126 B CN 102424126B CN 201110243634 CN201110243634 CN 201110243634 CN 201110243634 A CN201110243634 A CN 201110243634A CN 102424126 B CN102424126 B CN 102424126B
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Abstract
The invention discloses a standard substance vacuum subpackaging device and method for a hematology analyzer. The standard substance vacuum subpackaging device for the hematology analyzer comprises a bottle body, an infusion catheter, a puncture needle and a vacuum blood collection tube, wherein a ventilation needle is connected to the bottle body; one end of the infusion catheter is communicated with the bottle body, and the other end of the infusion catheter is connected with the puncture needle; and a nozzle of the vacuum blood collection tube is provided with a rubber hose cap capable of being inserted by the puncture needle and automatically sealing a needle eye after the puncture needle is pulled out. The method comprises the following steps of: a. filling a standard substance for the hematology analyzer to the bottle body; b. mixing uniformly; and c. subpackaging in vacuum. The subpackaging device has the advantages of simple structure and lower cost. In the subpackaging method, the standard substance is uniformly mixed by slowly overturning the bottle body, blood cells are less shaken, and thus, the cell morphology is not damaged while the uniform mixing quality is effectively guaranteed.
Description
Technical field
The present invention relates to a kind of blood analyser standard substance vacuum packaging device, the invention still further relates to a kind of blood analyser standard substance vacuum method for filling.
Background technology
Blood analyser mainly is to calibrate blood analyser with the mixed solution that reference material normally is comprised of animal blood cell, latex particle, proportioning reagent etc.Its requirement has extraordinary homogeneity, stability.
The blood analyser reference material shelf-life is short, usually only has 3 months to half a year, and price comparison is high, and therefore every batch of production quantity is few; And because the particularity of blood cell, the blood cell film is very thin, fragile, and cell membrane is easily damaged, therefore can not adopt the common violent blending manner such as concussion mixing, bubble mixing, rabble mixing.Traditional liquid vacuum filling machine is not suitable for the can of blood analyser reference material owing to involving great expense and the good reason such as Cell protection.
Summary of the invention
The technical problem to be solved in the present invention is: a kind of blood analyser standard substance vacuum packaging device simple in structure, that cost is low is provided, and easily blood analyser standard substance vacuum method for filling of a kind of enforcement is provided.
In order to solve the problems of the technologies described above, blood analyser of the present invention comprises bottle, hydraulic pipe, puncture needle and vacuum test tube with the standard substance vacuum packaging device, bottle is connected with vent wire, one end of hydraulic pipe is communicated with bottle, the other end connecting puncture needle of hydraulic pipe, the mouth of pipe of vacuum test tube is extracted the rubber pipe cap of rear pinprick automatic-sealed closure with inserting puncture needle and puncture needle.
For the mixing of Easy-used bottle substance in vivo, described bottle is connected with and drives the actuating device that bottle turns upside down.
The speed of putting upside down for the ease of the control bottle, described actuating device comprises frame, bottle clip and stepping motor, and bottle clip is fixed on rotates on the transmission shaft that is arranged on the frame, and stepping motor is arranged on the frame, the output shaft of stepping motor is connected with transmission shaft, and bottle is arranged in the bottle clip.
For the ease of drawing materials, described bottle is saline bottle, and described hydraulic pipe is silicone tube.
Blood analyser of the present invention standard substance vacuum method for filling, this method adopts aforesaid packaging device, and this method comprises the steps: that a is contained in blood analyser in the bottle with reference material; The b mixing: the bottle that continues to turn upside down makes material mixing in the bottle, and the speed that bottle turns upside down is 10-15 beats/min; C vacuum packing: in the process that turns upside down of bottle, puncture needle is thrust vacuum test tube, blood analyser is with flowing into vacuum test tube from bottle under the attraction of reference material negative pressure in vacuum test tube, vacuum test tube Plays material is extracted puncture needle after arriving quantitatively, continues the packing of next vacuum test tube.
Material flows to vacuum test tube in the bottle in order more to be conducive to, and among the described step c, when the vacuum test tube packing, vacuum test tube is positioned at the below of bottle.
Make cell membrane damaged at the bottom of the pipe that directly falls into vacuum test tube because of blood analyser with reference material, among the described step c, puncture needle is oblique lower insertion vacuum test tube, and the syringe needle of puncture needle is leaned against on the tube wall of vacuum test tube.
Beneficial effect of the present invention: packaging device of the present invention is simple in structure, and cost is lower.Method for filling of the present invention adopts bottle slowly to put upside down up and down mixing, and the vibrations that blood cell is subjected to are little, is effectively guaranteeing can not destroy cellular morphology in the bed blending quality.And adopt stepping motor driving bottle and turn upside down, when packing, only need an operating personal to finish, do not need other accessory equipment, convenient and easy.
Description of drawings
Fig. 1 is the structural representation of packaging device of the present invention;
Among the figure: 1, bottle, 2, vent wire, 3, hydraulic pipe, 4, puncture needle, 5, vacuum test tube, 6, frame, 7, bottle clip, 8, stepping motor.
The specific embodiment
A kind of blood analyser standard substance vacuum packaging device as shown in Figure 1, it comprises bottle 1, hydraulic pipe 3, puncture needle 4, vacuum test tube 5 and drives the actuating device that bottle 1 turns upside down.Actuating device comprises frame 6, bottle clip 7 and stepping motor 8, and frame 6 is provided with rotating transmission shaft, and bottle clip 7 is fixed on the transmission shaft, being arranged on the frame 6 of stepping motor 8, and the output shaft of stepping motor 8 is connected with transmission shaft, and bottle 1 is arranged in the bottle clip 7.
Bottle 1 is connected with vent wire 2, one end of hydraulic pipe 3 is communicated with bottle 1, the other end connecting puncture needle 4 of hydraulic pipe 3, the mouth of pipe of vacuum test tube 5 is extracted the rubber pipe cap of rear pinprick automatic-sealed closure with inserting puncture needle 4 and puncture needle 4, can be the common rubber pipe cap that is used for the encapsulation medicine bottle.
Bottle 1 can adopt saline bottle, also can adopt other bottle, and hydraulic pipe 3 also can adopt the body of other material.
Adopt the blood analyser standard substance vacuum method for filling of above-mentioned packaging device, comprise the steps:
A is contained in blood analyser in the bottle 1 with reference material, with bottle clip 7 bottle 1 is fixed;
B mixing: the switch of opening stepping motor 8, continue up and down 180 ° by stepping motor 8 control bottles 1 and put upside down, make bottle 1 interior material mixing, bottle 1 speed that turns upside down all can in 10-15 beats/min, the mixing that this speed can guarantee material in the bottle can not destroy the blood cell film again.
C carries out the vacuum packing in mixing: in the process that turns upside down of bottle 1 puncture needle 4 is thrust vacuum test tube 5, blood analyser is with flowing into vacuum test tube 5 from bottle 1 under the attraction of reference material negative pressure in vacuum test tube 5, vacuum test tube 5 Plays materials are extracted puncture needle 4 after arriving quantitatively, continue the packing of next vacuum test tube 5.The aforesaid 2ml that quantitatively is generally, vacuum test tube 5 is marked with the 2ml scale mark.During vacuum test tube 5 packing, vacuum test tube 5 preferably is positioned at the below of bottle 1, so more is conducive to blood analyser and flows in vacuum test tube 5 with reference material.When inserting puncture needle 4, preferably with puncture needle 4 oblique lower insertion vacuum test tubes 5, the syringe needle of puncture needle 4 is leaned against on the tube wall of vacuum test tube 5, blood analyser is flowed downward, to avoid making cell membrane damaged because of blood analyser directly fall into the pipe of vacuum test tube 5 with reference material at the bottom of with the tube wall of reference material along vacuum test tube 5.
Claims (5)
1. blood analyser standard substance vacuum packaging device, it is characterized in that: comprise bottle (1), hydraulic pipe (3), puncture needle (4) and vacuum test tube (5), bottle (1) is connected with vent wire (2), one end of hydraulic pipe (3) is communicated with bottle (1), the other end connecting puncture needle (4) of hydraulic pipe (3), the mouth of pipe of vacuum test tube (5) is with inserting puncture needle (4), and puncture needle (4) is extracted the rubber pipe cap of rear pinprick automatic-sealed closure, described bottle (1) is connected with and drives the actuating device that bottle turns upside down, described actuating device comprises frame (6), bottle clip (7) and stepping motor (8), bottle clip (7) is fixed on rotates on the transmission shaft that is arranged on the frame (6), stepping motor (8) is arranged on the frame (6), the output shaft of stepping motor (8) is connected with transmission shaft, and bottle (1) is arranged in the bottle clip (7).
2. blood analyser according to claim 1 standard substance vacuum packaging device, it is characterized in that: described bottle (1) is saline bottle, and described hydraulic pipe (3) is silicone tube.
3. a blood analyser standard substance vacuum method for filling that adopts packaging device as claimed in claim 1 or 2 is characterized in that: comprise the steps: that a is contained in blood analyser in the bottle (1) with reference material; The b mixing: the bottle (1) that continues to turn upside down makes the interior material mixing of bottle (1), and the speed that bottle (1) turns upside down is 10-15 beats/min; C vacuum packing: in the process that turns upside down of bottle (1), puncture needle (4) is thrust vacuum test tube (5), blood analyser is with flowing into vacuum test tube (5) from bottle (1) under the attraction of reference material negative pressure in vacuum test tube (5), vacuum test tube (5) Plays material is extracted puncture needle (4) after arriving quantitatively, continues the packing of next vacuum test tube (5).
4. blood analyser according to claim 3 standard substance vacuum method for filling, it is characterized in that: among the described step c, when vacuum test tube (5) packing, vacuum test tube (5) is positioned at the below of bottle (1).
5. blood analyser according to claim 3 standard substance vacuum method for filling, it is characterized in that: among the described step c, puncture needle (4) is oblique lower insertion vacuum test tube (5), and the syringe needle of puncture needle (4) is leaned against on the tube wall of vacuum test tube (5).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110243634 CN102424126B (en) | 2011-08-24 | 2011-08-24 | Standard substance vacuum subpackaging device and method for hematology analyzer |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110243634 CN102424126B (en) | 2011-08-24 | 2011-08-24 | Standard substance vacuum subpackaging device and method for hematology analyzer |
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| CN102424126A CN102424126A (en) | 2012-04-25 |
| CN102424126B true CN102424126B (en) | 2013-03-27 |
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| CN 201110243634 Active CN102424126B (en) | 2011-08-24 | 2011-08-24 | Standard substance vacuum subpackaging device and method for hematology analyzer |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5270219A (en) * | 1989-07-14 | 1993-12-14 | Gds Technology, Inc. | Fluid transfer device |
| CN2306190Y (en) * | 1997-06-13 | 1999-02-03 | 李卫东 | Multifunctional automatic quantitative filling machine |
| CN1489542A (en) * | 2001-02-12 | 2004-04-14 | ��˹�ٶ�ҽѧ��������˾ | Midicament vial having heat-sealable cap and device and method for filling said vial |
| CN1662307A (en) * | 2002-05-13 | 2005-08-31 | 贝克顿·迪金森公司 | Protease inhibitor sample collection system |
| CN201595829U (en) * | 2010-02-22 | 2010-10-06 | 韩蔚伟 | Blood sampling bottle for examining blood |
| CN202208373U (en) * | 2011-08-24 | 2012-05-02 | 山东兰桥医学科技有限公司 | Standard substance vacuum split charging device for blood analyzer |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2918958B1 (en) * | 2007-07-18 | 2009-10-16 | Normandie Appats Soc Par Actio | FILLING DEVICE AND METHOD FOR TRAY |
-
2011
- 2011-08-24 CN CN 201110243634 patent/CN102424126B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5270219A (en) * | 1989-07-14 | 1993-12-14 | Gds Technology, Inc. | Fluid transfer device |
| CN2306190Y (en) * | 1997-06-13 | 1999-02-03 | 李卫东 | Multifunctional automatic quantitative filling machine |
| CN1489542A (en) * | 2001-02-12 | 2004-04-14 | ��˹�ٶ�ҽѧ��������˾ | Midicament vial having heat-sealable cap and device and method for filling said vial |
| CN1662307A (en) * | 2002-05-13 | 2005-08-31 | 贝克顿·迪金森公司 | Protease inhibitor sample collection system |
| CN201595829U (en) * | 2010-02-22 | 2010-10-06 | 韩蔚伟 | Blood sampling bottle for examining blood |
| CN202208373U (en) * | 2011-08-24 | 2012-05-02 | 山东兰桥医学科技有限公司 | Standard substance vacuum split charging device for blood analyzer |
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| CN102424126A (en) | 2012-04-25 |
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Effective date of registration: 20200903 Address after: 117 / F, No. 166 Meiyue Road, pilot Free Trade Zone, Pudong New Area, Shanghai, 200131 Patentee after: Shanghai Lanqiao Biotechnology Co., Ltd Address before: Yaoqiang airport Licheng District 250107 Shandong road Ji'nan City, No. 7166 Patentee before: STAC MEDICAL SCIENCE & TECHNOLOGY Co.,Ltd. |