CN102424126A - Standard substance vacuum subpackaging device and method for hematology analyzer - Google Patents

Standard substance vacuum subpackaging device and method for hematology analyzer Download PDF

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Publication number
CN102424126A
CN102424126A CN2011102436346A CN201110243634A CN102424126A CN 102424126 A CN102424126 A CN 102424126A CN 2011102436346 A CN2011102436346 A CN 2011102436346A CN 201110243634 A CN201110243634 A CN 201110243634A CN 102424126 A CN102424126 A CN 102424126A
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China
Prior art keywords
bottle
vacuum
test tube
puncture needle
reference material
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CN2011102436346A
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CN102424126B (en
Inventor
韩作湘
王国锋
王春莲
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Shanghai Lanqiao Biotechnology Co., Ltd
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Shandong STAC Medical Science And Technology Co Ltd
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Abstract

The invention discloses a standard substance vacuum subpackaging device and method for a hematology analyzer. The standard substance vacuum subpackaging device for the hematology analyzer comprises a bottle body, an infusion catheter, a puncture needle and a vacutainer, wherein a ventilation needle is connected to the bottle body; one end of the infusion catheter is communicated with the bottle body, and the other end of the infusion catheter is connected with the puncture needle; and a nozzle of the vacutainer is provided with a rubber hose cap capable of being inserted by the puncture needle and automatically sealing a needle eye after the puncture needle is pulled out. The method comprises the following steps of: a. filling a standard substance for the hematology analyzer to the bottle body; b. mixing uniformly; and c. subpackaging in vacuum. The subpackaging device has the advantages of simple structure and lower cost. In the subpackaging method, the standard substance is uniformly mixed by slowly overturning the bottle body, blood cells are less shaken, therefore, the cell morphology is not damaged while the uniform mixing quality is effectively guaranteed.

Description

Blood analyser is with reference material vacuum packaging device and method for filling
Technical field
The present invention relates to a kind of blood analyser with reference material vacuum packaging device, the invention still further relates to a kind of blood analyser with reference material vacuum method for filling.
Background technology
The mixed solution that blood analyser normally is made up of animal haemocyte, latex particle, proportioning reagent etc. with reference material mainly is to be used for calibrating blood analyser.Its requirement has extraordinary homogeneity, stability.
The blood analyser reference material shelf-life is short, has only 3 months usually to half a year, and price comparison is high, and therefore every batch of production quantity is few; And because the particularity of blood cell, the blood cell film is extremely thin, fragile, and cell membrane is damaged easily, therefore can not adopt common violent blending manner such as concussion mixing, bubble mixing, rabble mixing.Traditional liquid vacuum bottle placer is not suitable for the can of blood analyser reference material owing to involving great expense and can not well protecting reasons such as cell.
Summary of the invention
The technical matters that the present invention will solve is: provide a kind of simple in structure, blood analyser that cost is low with reference material vacuum packaging device, and provide a kind of enforcement easily blood analyser with reference material vacuum method for filling.
In order to solve the problems of the technologies described above; Blood analyser of the present invention comprises bottle, hydraulic pipe, puncture needle and vacuum test tube with reference material vacuum packaging device; Bottle is connected with vent wire; One end of hydraulic pipe is communicated with bottle, and the other end of hydraulic pipe connects puncture needle, and the mouth of pipe of vacuum test tube has can insert puncture needle and puncture needle is extracted the closed rubber pipe cap of back pinprick automatic seal.
The mixing of material in the bottle for ease, described bottle is connected with and drives the actuating device that bottle turns upside down.
The speed of putting upside down for the ease of the control bottle; Described actuating device comprises frame, bottle folder and stepping motor, and the bottle clamping fixes on to rotate and is arranged on the transmission shaft on the frame, and stepping motor is arranged on the frame; The output shaft of stepping motor is connected with transmission shaft, and bottle is arranged in the bottle folder.
For the ease of drawing materials, described bottle is a saline bottle, and described hydraulic pipe is a silicone tube.
Blood analyser of the present invention is with reference material vacuum method for filling, and this method adopts aforesaid packaging device, and this method comprises the steps: that a is contained in blood analyser in the bottle with reference material; The b mixing: the bottle that continues to turn upside down makes material mixing in the bottle, and the speed that bottle turns upside down is 10-15 time/minute; C vacuum packing: in the process that turns upside down of bottle, puncture needle is thrust vacuum test tube; Blood analyser is with flowing into vacuum test tube from bottle under the attraction of reference material negative pressure in vacuum test tube; Reference material is extracted puncture needle after arriving quantitatively in the vacuum test tube, continues the packing of next vacuum test tube.
Material flows to vacuum test tube in the bottle in order more to help, and among the described step c, when the vacuum test tube packing, vacuum test tube is positioned at the below of bottle.
At the bottom of the pipe that directly falls into vacuum test tube because of blood analyser with reference material, make cell membrane damaged, among the described step c, puncture needle is the oblique vacuum test tube of insertion down, and the syringe needle of puncture needle is leaned against on the tube wall of vacuum test tube.
Beneficial effect of the present invention: packaging device of the present invention is simple in structure, and cost is lower.Method for filling of the present invention adopts bottle slowly to put upside down mixing up and down, and the vibrations that blood cell receives are little, is effectively guaranteeing can not destroy cellular morphology in the mixing quality.And adopt the step motor drive bottle and turn upside down, when packing, only need an operating personal to accomplish, do not need other accessory equipment, convenient and easy.
Description of drawings
Fig. 1 is the structural representation of packaging device of the present invention;
Among the figure: 1, bottle, 2, vent wire, 3, hydraulic pipe, 4, puncture needle, 5, vacuum test tube, 6, frame, 7, the bottle folder, 8, stepping motor.
The specific embodiment
A kind of blood analyser as shown in Figure 1 is with reference material vacuum packaging device, and it comprises bottle 1, hydraulic pipe 3, puncture needle 4, vacuum test tube 5 and drives the actuating device that bottle 1 turns upside down.Actuating device comprises frame 6, bottle folder 7 and stepping motor 8, and frame 6 is provided with rotating transmission shaft, and bottle folder 7 is fixed on the transmission shaft, being arranged on the frame 6 of stepping motor 8, and the output shaft of stepping motor 8 is connected with transmission shaft, and bottle 1 is arranged on and bottle presss from both sides in 7.
Bottle 1 is connected with vent wire 2; One end of hydraulic pipe 3 is communicated with bottle 1; The other end of hydraulic pipe 3 connects puncture needle 4; The mouth of pipe of vacuum test tube 5 has and can insert puncture needle 4 and puncture needle 4 and extract the closed rubber pipe cap of back pinprick automatic seal, can be the rubber pipe cap that common being used to encapsulates medicine bottle.
Bottle 1 can adopt saline bottle, also can adopt other bottle, and hydraulic pipe 3 also can adopt the body of other material.
The blood analyser that adopts above-mentioned packaging device comprises the steps: with reference material vacuum method for filling
A is contained in blood analyser in the bottle 1 with reference material, with bottle folder 7 bottle 1 is fixed;
The b mixing: open the switch of stepping motor 8, put upside down for 180 ° about continuing through stepping motor 8 control bottles 1, make material mixing in the bottle 1, the speed that bottle 1 turns upside down is 15 times/minute; Bottle 1 turn upside down speed in 10-15 time/minute all can, the mixing that this speed can guarantee material in the bottle can not destroy the blood cell film again.
C carries out the vacuum packing in mixing: in the process that turns upside down of bottle 1, puncture needle 4 is thrust vacuum test tube 5; Blood analyser is with flowing into vacuum test tube 5 from bottle 1 under the attraction of reference material negative pressure in vacuum test tube 5; Reference material is extracted puncture needle 4 after arriving quantitatively in the vacuum test tube 5, continues the packing of next vacuum test tube 5.The aforesaid 2ml that quantitatively is generally, vacuum test tube 5 is marked with the 2ml scale mark.During vacuum test tube 5 packing, vacuum test tube 5 preferably is positioned at the below of bottle 1, so more helps blood analyser and flows in vacuum test tube 5 with reference material.When inserting puncture needle 4; Preferably with the puncture needle 4 oblique vacuum test tubes 5 that insert down; The syringe needle of puncture needle 4 is leaned against on the tube wall of vacuum test tube 5; Blood analyser is flowed downward, to avoid making cell membrane damaged directly fall into the pipe of vacuum test tube 5 with reference material at the bottom of because of blood analyser with the tube wall of reference material along vacuum test tube 5.

Claims (7)

1. a blood analyser is with reference material vacuum packaging device; It is characterized in that: comprise bottle (1), hydraulic pipe (3), puncture needle (4) and vacuum test tube (5); Bottle (1) is connected with vent wire (2); One end of hydraulic pipe (3) is communicated with bottle (1), and the other end of hydraulic pipe (3) connects puncture needle (4), and the mouth of pipe of vacuum test tube (5) has can insert puncture needle (4) and puncture needle (4) is extracted the closed rubber pipe cap of back pinprick automatic seal.
2. blood analyser according to claim 1 is characterized in that with reference material vacuum packaging device: described bottle (1) is connected with and drives the actuating device that bottle turns upside down.
3. blood analyser according to claim 2 is with reference material vacuum packaging device; It is characterized in that: described actuating device comprises frame (6), bottle folder (7) and stepping motor (8); Bottle folder (7) is fixed on to rotate and is arranged on the transmission shaft on the frame (6); Stepping motor (8) is arranged on the frame (6), and the output shaft of stepping motor (8) is connected with transmission shaft, and bottle (1) is arranged in the bottle folder (7).
According to claim 1,2 or 3 described blood analysers with reference material vacuum packaging device, it is characterized in that: described bottle (1) is a saline bottle, and described hydraulic pipe (3) is a silicone tube.
5. the blood analyser of an employing such as claim 1 or 2 or 3 described packaging devices is characterized in that: comprise the steps: that a is contained in blood analyser in the bottle (1) with reference material with reference material vacuum method for filling; The b mixing: the bottle (1) that continues to turn upside down makes the interior material mixing of bottle (1), and the speed that bottle (1) turns upside down is 10-15 time/minute; C vacuum packing: in the process that turns upside down of bottle (1), puncture needle (4) is thrust vacuum test tube (5); Blood analyser is with flowing into vacuum test tube (5) from bottle (1) under the attraction of reference material negative pressure in vacuum test tube (5); Reference material is extracted puncture needle (4) after arriving quantitatively in the vacuum test tube (5), continues the packing of next vacuum test tube (5).
6. blood analyser according to claim 5 is characterized in that with reference material vacuum method for filling: among the described step c, when vacuum test tube (5) packing, vacuum test tube (5) is positioned at the below of bottle (1).
7. blood analyser according to claim 5 is with reference material vacuum method for filling; It is characterized in that: among the described step c; Puncture needle (4) is the oblique vacuum test tube (5) of insertion down, and the syringe needle of puncture needle (4) is leaned against on the tube wall of vacuum test tube (5).
CN 201110243634 2011-08-24 2011-08-24 Standard substance vacuum subpackaging device and method for hematology analyzer Active CN102424126B (en)

Priority Applications (1)

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CN 201110243634 CN102424126B (en) 2011-08-24 2011-08-24 Standard substance vacuum subpackaging device and method for hematology analyzer

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CN 201110243634 CN102424126B (en) 2011-08-24 2011-08-24 Standard substance vacuum subpackaging device and method for hematology analyzer

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CN102424126A true CN102424126A (en) 2012-04-25
CN102424126B CN102424126B (en) 2013-03-27

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5270219A (en) * 1989-07-14 1993-12-14 Gds Technology, Inc. Fluid transfer device
CN2306190Y (en) * 1997-06-13 1999-02-03 李卫东 Multifunctional automatic quantitative filling machine
CN1489542A (en) * 2001-02-12 2004-04-14 ��˹�ٶ�ҽѧ�������޹�˾ Midicament vial having heat-sealable cap and device and method for filling said vial
CN1662307A (en) * 2002-05-13 2005-08-31 贝克顿·迪金森公司 Protease inhibitor sample collection system
US20100193068A1 (en) * 2007-07-18 2010-08-05 Normandie Appats Device and method for filling trays
CN201595829U (en) * 2010-02-22 2010-10-06 韩蔚伟 Blood sampling bottle for examining blood
CN202208373U (en) * 2011-08-24 2012-05-02 山东兰桥医学科技有限公司 Standard substance vacuum split charging device for blood analyzer

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5270219A (en) * 1989-07-14 1993-12-14 Gds Technology, Inc. Fluid transfer device
CN2306190Y (en) * 1997-06-13 1999-02-03 李卫东 Multifunctional automatic quantitative filling machine
CN1489542A (en) * 2001-02-12 2004-04-14 ��˹�ٶ�ҽѧ�������޹�˾ Midicament vial having heat-sealable cap and device and method for filling said vial
CN1662307A (en) * 2002-05-13 2005-08-31 贝克顿·迪金森公司 Protease inhibitor sample collection system
US20100193068A1 (en) * 2007-07-18 2010-08-05 Normandie Appats Device and method for filling trays
CN201595829U (en) * 2010-02-22 2010-10-06 韩蔚伟 Blood sampling bottle for examining blood
CN202208373U (en) * 2011-08-24 2012-05-02 山东兰桥医学科技有限公司 Standard substance vacuum split charging device for blood analyzer

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Effective date of registration: 20200903

Address after: 117 / F, No. 166 Meiyue Road, pilot Free Trade Zone, Pudong New Area, Shanghai, 200131

Patentee after: Shanghai Lanqiao Biotechnology Co., Ltd

Address before: Yaoqiang airport Licheng District 250107 Shandong road Ji'nan City, No. 7166

Patentee before: STAC MEDICAL SCIENCE & TECHNOLOGY Co.,Ltd.

TR01 Transfer of patent right