CN102415397B - Synergia insecticide composition containing dinotefuran and chlorfluazuron and application thereof - Google Patents
Synergia insecticide composition containing dinotefuran and chlorfluazuron and application thereof Download PDFInfo
- Publication number
- CN102415397B CN102415397B CN 201010299835 CN201010299835A CN102415397B CN 102415397 B CN102415397 B CN 102415397B CN 201010299835 CN201010299835 CN 201010299835 CN 201010299835 A CN201010299835 A CN 201010299835A CN 102415397 B CN102415397 B CN 102415397B
- Authority
- CN
- China
- Prior art keywords
- mti
- fluorine pyridine
- pyridine urea
- chlorfluazuron
- application
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
The invention discloses a synergia insecticide composition containing dinotefuran and chlorfluazuron and an application thereof. The synergia insecticide composition uses the dinotefuran and the chlorfluazuron as major effective ingredients, wherein the weight ratio of the dinotefuran to the chlorfluazuron is (0.1 to 80)/(0.5 to 80). The insecticide composition is used for preventing and treating various kinds of pests such as lepidoptera pests, homoptera pests, hymenoptera pests, coleoptera pests and the like and has the effects of prevention and treatment range expansion and effect enhancement, and in addition, the medication cost can be reduced.
Description
Technical field
The invention belongs to pesticide field, be specifically related to a kind of Pesticidal combination and application thereof that MTI-446 and fluorine pyridine urea be main active ingredient of take.
Background technology
MTI-446 (dinotefuran), chemical name: 1-methyl-2-nitro-3-(tetrahydrochysene-3-furfuryl) guanidine, white crystal, 107.5 ℃ of fusing points, 94.5～101.5 ℃ of industrial goods, vapour pressure<1.7 * 10-6pa (30 ℃), density 1.33 (25 ℃).Solvability is water 40g/L, is insoluble in cyclohexane, solvent wet goods organic solvent.Structural formula is:
MTI-446 is fool proof to mammal, and its acute oral LD50 is male rat 2450mg/kg, female rats 2275mg/kg; Male mice 2840mg/kg, female mice 2000mg/kg.To rat acute through skin LD50>2000mg/kg (female, hero).Without teratogenesis, carcinogenic and mutagenicity.MTI-446 is also fool proof to aquatile.Ichthyotoxin is tested and is shown, MTI-446 is to carp nm (48h)>1000mg/L, to water flea>1000mg/L; Equally, MTI-446 is also very low to birds toxicity, and to quail acute oral LD50>1000mg/kg., through the honeybee test is learnt, MTI-446 is to honeybee safety, and do not affect honeybee producting honey.This medicament insecticidal spectrum is wide, has remarkable interior sorptivety and thoroughly acts on, and shown very high insecticidal activity at very low dosage.This medicament is fool proof to mammal, birds and aquatile, and crop, without poisoning, be can be used for to numerous crops such as paddy rice, fruit tree, vegetables.
Fluorine pyridine urea (Chlorfluazuron), chemical name: 1-(the chloro-4-of 3,5-bis-(the chloro-5-trifluoromethyl of 3--2-pyridine oxygen base) phenyl)-3-(2,6-difluoro benzoyl) urea, structural formula is:
Fluorine pyridine urea is a kind of widely used growth regulator, tool stomach toxicity, action of contace poison.The mechanism of action is to suppress chitin synthesis, hinders insect and normally casts off a skin, and makes the developmental deformity of hatching, larval molting and the pupa of ovum, and adult eclosion is obstructed.Drug effect is high, and speed of action is slower, and to multiple lepidoptera pest, and orthoptera, coleoptera, Hymenoptera, diptera isoreactivity are high, but invalid to aphid, leafhopper, plant hopper.Fluorine pyridine urea is to mammiferous acute through skin LD
50>8500mg/kg, acute oral LD
50>1000mg/kg.
Often there is defect in insecticide variety containing single component in the agricultural chemicals control of insect: use is easily developed immunity to drugs continuously, and insecticidal spectrum is narrow, can not provide comprehensive protection for crop, and peasant's drug cost is high.The inventor finds by research, and the combination by two kinds or more of active components is the above-mentioned shortcoming of customer service to a certain extent.
Summary of the invention
The purpose of this invention is to provide a kind of Synergistic insecticidal compositions containing MTI-446 and fluorine pyridine urea, said composition can be used for preventing and treating the various agricultural insect, for example, in control paddy rice rice leaf roller, striped rice borer, paddy stem borer, pink rice borer, rice plant skipper, can prevent that again rice fulgorid, rice silk worm are first-class, can reach the effect that a drug is prevented and treated dissimilar insect.
Another object of the present invention is to provide containing the Synergistic insecticidal compositions of MTI-446 and fluorine pyridine urea and prevents and treats the application in the insecticidal materials of one or more insects in resistance Lepidoptera, Homoptera, Hymenoptera or coleoptera in preparation.
The present invention adopts following technical scheme:
A kind of Synergistic insecticidal compositions containing MTI-446 and fluorine pyridine urea, it take MTI-446 and fluorine pyridine urea is main active ingredient, and wherein, the weight ratio of MTI-446 and fluorine pyridine urea is 0.1～80: 0.5～80, be preferably 1～60: 1～70, more preferably 1～30: 1～30.The effective ingredient of above-mentioned Insecticidal combinations is present in composition with the synergy effective dose.
At the Synergistic insecticidal compositions containing MTI-446 and fluorine pyridine urea of the present invention, MTI-446 and the two weight percentage in this Synergistic insecticidal compositions of fluorine pyridine urea are 2%～80%, are preferably 8%～60%, and optimum is 20%～40%.
The above-mentioned Synergistic insecticidal compositions containing MTI-446 and fluorine pyridine urea be take MTI-446 and fluorine pyridine urea and is mixed with any one formulation allowed on agricultural chemicals as main active ingredient (active component) and insecticides adjuvant, excipients.The preferred pulvis of formulation, wetting powder, suspending agent, missible oil and water dispersion granule.
Described auxiliary agent can adopt calcium dodecyl benzene sulfonate, alkylphenol polyoxyethylene, the rare block compound of polyoxyethylene polyoxy third (as agriculture breast 33
#), the conventional auxiliary agent such as polyoxyethylene nonylphenol ether, excipient comprises cyclohexanone, dimethylbenzene, solvent naphtha, water, antifreezing agent (as propane diols), deionized water etc.Above auxiliary agent, excipient and the upper known auxiliary material of other agricultural can alone or mixing use.
Synergistic insecticidal compositions antagonism lepidoptera pest of the present invention has significant preventive effect, especially for the easy various pests that produces resistance such as rice leaf roller, striped rice borer, paddy stem borer, pink rice borer, rice plant skipper, has good preventive effect; And suppress insect to the pesticide resistance generation of unitary agent (MTI-446 or fluorine pyridine urea) and simultaneously can prevent and treat homoptera pest as rice fulgorid, aleyrodid, leafhopper etc., reach the effect that a medicine is controlled more.The above-mentioned Synergistic insecticidal compositions containing MTI-446 and fluorine pyridine urea can be applicable to the insecticidal materials of one or more insects in preparation control Lepidoptera, Homoptera, Hymenoptera or coleoptera, is particularly useful for the insecticidal materials of preparation control rice fulgorid or snout moth's larva.
Pesticidal combination of the present invention compared with prior art, produce following beneficial effect: the insecticidal materials that said composition prepares is for preventing and treating Lepidoptera, Homoptera, Hymenoptera or coleopteran pest, obvious synergistic function is arranged, and a medicine is controlled more, a dispenser can prevent and treat various pests simultaneously, reduces control recruitment cost; Alternative high-toxic pesticide, and significantly reduce the field dosage, effective environmental contamination reduction and residue of pesticide; Have concurrently quick-acting and long-acting; Compare with the MTI-446 single dose, produce and the use cost reduction; Suppress the resistance enhancing of insect to agricultural chemicals.
Embodiment
Embodiments of the invention are the methods that adopt indoor bioassay and field trial to combine.First by indoor bioassay, the co-toxicity coefficient after clear and definite two kinds of medicaments are composite by a certain percentage; On this basis, then carry out field trial.
Embodiment 1:
Taking MTI-446, fluorine pyridine urea adopts the conventional formulation method to be mixed with by different proportion the MTI-446 5 percent of hexaflumuron emulsifiable concentrate that main active ingredient weight percentage is 30%.Concrete ratio is in Table 1.The contrast medicament is respectively 30% MTI-446 missible oil and 30% 5 percent of hexaflumuron emulsifiable concentrate.
Adopt feed to add malicious method and measure MTI-446 and fluorine pyridine urea and composite sample thereof the virulence to rice-stem borer, every processing repeats 3 times, and every concentration is processed 30, uses LC
50value is pressed the abundant method of Sun Yun and is calculated co-toxicity coefficient:
Table 1 MTI-446, fluorine pyridine urea and composite sample thereof toxicity test and the co-toxicity coefficient to rice-stem borer
In table, data show, MTI-446 and fluorine pyridine urea are mixed and rear rice-stem borer are had to synergistic effect, and four proportioning co-toxicity coefficients listed in table are all much larger than 120, so MTI-446 and fluorine pyridine urea are mixed and have significant synergies.The synergistic effect maximum that wherein when the ratio of fluorine pyridine urea and MTI-446 is 5: 1, is mixed and kills rice-stem borer, co-toxicity coefficient is 200.12.
Embodiment 2:
Taking MTI-446, fluorine pyridine urea adopts the conventional formulation method to be mixed with by different proportion the MTI-446 5 percent of hexaflumuron emulsifiable concentrate that main active ingredient weight percentage is 30%.The contrast medicament is respectively 30% MTI-446 missible oil and 30% 5 percent of hexaflumuron emulsifiable concentrate, and concrete ratio is in Table 2.
Adopt rice stem infusion process to measure MTI-446 and fluorine pyridine urea and composite sample thereof the virulence to Brown Planthopper, every processing repeats 3 times, uses LC
50value is pressed the abundant method of Sun Yun and is calculated co-toxicity coefficient:
Table 2 MTI-446, fluorine pyridine urea and composite sample thereof toxicity test and the co-toxicity coefficient to Brown Planthopper
In table, data show, MTI-446 and fluorine pyridine urea are mixed and rear brown planthopper are had to synergistic effect, and four proportioning co-toxicity coefficients listed in table are all much larger than 120, so MTI-446 and fluorine pyridine urea are mixed and have significant synergies.The synergistic effect maximum that wherein when the ratio of MTI-446 and fluorine pyridine urea is 1: 10, is mixed and kills the paddy rice Brown Planthopper, co-toxicity coefficient is 220.14.
Embodiment 3:
Take 5g MTI-446,20g fluorine pyridine urea, calcium dodecyl benzene sulfonate 4g, phenethyl phenol polyethenoxy ether 3g, dimethylbenzene to 100g, the method that above raw material is prepared to missible oil routinely drops in mixing kettle mixes, and forms the MTI-446 5 percent of hexaflumuron emulsifiable concentrate that main active ingredient weight percentage is 25%.
Adopt 3 sample product of embodiment to carry out the field trial of control in field Brown Planthopper, the contrast medicament is 25% MTI-446 WP and 25% fluorine pyridine urea EC, and concrete consumption is in Table 3, every mu of water consumption is 30kg, looks into 7 days after medicine 3 days, 14 days, 28 days results, result of the test is in Table 3:
The field test results of table 3 example 3 samples to Brown Planthopper
3 pairs of Brown Planthoppers of example have fabulous quick-acting as can be seen from Table 3, and the lasting period is more intense, in the field performance well, are the outstanding medicaments of control Brown Planthopper.
Embodiment 4:
Adopt 3 sample product of embodiment to carry out the field trial of control in field rice-stem borer, the contrast medicament is 25% MTI-446 WP (wetting powder) and 25% fluorine pyridine urea EC (missible oil), concrete consumption is in Table 3, every mu of water consumption is 30kg, after medicine, look into 3 days, 7 days, 14 days, 28 days results, result of the test is in Table 4:
The field test results of table 4 example 3 samples to rice-stem borer
Example 3 samples have fabulous effect to rice-stem borer as can be seen from Table 4, and the lasting period is long, in the field performance well, are the outstanding medicaments that prevents striped rice borer.
Measure and show through indoor synergism test: by MTI-446 and fluorine pyridine urea built agent, water rice hopper and striped rice borer are all had to significant synergistic insecticidal action; Field control effectiveness test equally also shows that all built agents of the present invention all are significantly higher than the effect of corresponding single dose agricultural chemicals to the insecticidal effect of water rice hopper and striped rice borer.
Embodiment 5:
Take 0.2g MTI-446,20g fluorine pyridine urea, sodium lignin sulfonate 10g, Negel 2g, with kaolin, add to 100g, above raw material is mixed in micronizer, form the MTI-446 fluorine pyridine urea wetting powder that main active ingredient weight percentage is 20.2%.
Embodiment 6:
Take 78g MTI-446,0.5g fluorine pyridine urea, calcium dodecyl benzene sulfonate 8g, phenethyl phenol polyethenoxy ether 6g, dimethylbenzene and add to 100g, the method that above raw material is prepared to missible oil routinely drops in mixing kettle mixes, and forms the MTI-446 5 percent of hexaflumuron emulsifiable concentrate that main active ingredient weight percentage is 78.5%.
Embodiment 7:
Take 2g MTI-446,10g fluorine pyridine urea, phenethyl phenol polyethenoxy ether phosphate 3g, agriculture breast 33
#(alkylaryl polyoxyethylene polyoxypropylene ether) 2g, alkylphenol polyoxyethylene 1g, vegetable oil 13g, add water to 100g.The method of above raw material being prepared routinely to aqueous emulsion drops into the mixing of mixing kettle high speed, forms the MTI-446 fluorine pyridine urea aqueous emulsion that main active ingredient weight percentage is 12%.
Embodiment 8:
Take 10g MTI-446,30g fluorine pyridine urea, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether phosphate 3g, agriculture breast 33
#(alkylaryl polyoxyethylene polyoxypropylene ether) 2g, alkylphenol polyoxyethylene 1g, isopropyl alcohol 10g, add water to 100g.The method that above raw material is prepared to microemulsion routinely drops in mixing kettle mixes, and forms the MTI-446 fluorine pyridine urea microemulsion that main active ingredient weight percentage is 40%.
Embodiment 9:
Take 4g MTI-446,4g fluorine pyridine urea, calcium dodecyl benzene sulfonate 5g, phenethyl phenol polyethenoxy ether 3g, dimethylbenzene to 100g.The method that above raw material is prepared to missible oil routinely drops in mixing kettle mixes, and forms the MTI-446 5 percent of hexaflumuron emulsifiable concentrate that main active ingredient weight percentage is 8%.
Embodiment 10:
Take 3g MTI-446,30g fluorine pyridine urea, sodium lignin sulfonate 3g, polyoxyethylene poly-oxygen propylene aether and sulphate 4g thereof, xanthans 0.2g, ethylene glycol 10g, silica ethane 0.1g, aluminium-magnesium silicate 0.5g, water is supplied 100g, forms the MTI-446 fluorine pyridine urea suspending agent that main active ingredient weight percentage is 33% under the effect of sand mill.
Embodiment 11:
Take 5g MTI-446,60g fluorine pyridine urea, alkylphenol polyoxyethylene 14g, phenethyl phenol polyethenoxy ether 15g, dimethylbenzene to 100g, the method that above raw material is prepared to missible oil routinely drops in mixing kettle mixes, and forms the MTI-446 5 percent of hexaflumuron emulsifiable concentrate that main active ingredient weight percentage is 65%.
Embodiment 12:
Take 45g MTI-446,5g fluorine pyridine urea, sodium lignin sulfonate 8g, lauryl sodium sulfate 2g, ammonium sulfate 5g, polyvinyl alcohol 5g, borax 2g, kaolin 28g, form by the method for water dispersion granule the MTI-446 fluorine pyridine urea water dispersible granules that main active ingredient weight percentage is 50% by above raw material.
Embodiment 13:
Take 25g MTI-446,25g fluorine pyridine urea, alkylphenol polyoxyethylene 14g, phenethyl phenol polyethenoxy ether 15g, dimethylbenzene to 100g, the method that above raw material is prepared to missible oil routinely drops in mixing kettle mixes, and forms the MTI-446 5 percent of hexaflumuron emulsifiable concentrate that main active ingredient weight percentage is 50%.
Claims (3)
1. the Synergistic insecticidal compositions containing MTI-446 and fluorine pyridine urea, it is characterized in that it is active ingredient that this Synergistic insecticidal compositions be take MTI-446 and fluorine pyridine urea, wherein, fluorine pyridine urea and MTI-446 adopt the conventional formulation method to be mixed with in 5:1 or 2.5:1 ratio the MTI-446 5 percent of hexaflumuron emulsifiable concentrate that the active ingredient weight percentage is 30%.
2. the application in the insecticidal materials of the Synergistic insecticidal compositions containing MTI-446 and fluorine pyridine urea claimed in claim 1 one or more insects in preparation control Lepidoptera, Homoptera, Hymenoptera or coleoptera.
3. application according to claim 2, is characterized in that the application of Synergistic insecticidal compositions in the insecticidal materials of preparation control rice fulgorid or snout moth's larva containing MTI-446 and fluorine pyridine urea.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010299835 CN102415397B (en) | 2010-09-28 | 2010-09-28 | Synergia insecticide composition containing dinotefuran and chlorfluazuron and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010299835 CN102415397B (en) | 2010-09-28 | 2010-09-28 | Synergia insecticide composition containing dinotefuran and chlorfluazuron and application thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102415397A CN102415397A (en) | 2012-04-18 |
| CN102415397B true CN102415397B (en) | 2013-12-25 |
Family
ID=45940238
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201010299835 Active CN102415397B (en) | 2010-09-28 | 2010-09-28 | Synergia insecticide composition containing dinotefuran and chlorfluazuron and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102415397B (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1112556A (en) * | 1993-10-26 | 1995-11-29 | 三井东压化学株式会社 | Furanyl insecticide |
| CN1889842A (en) * | 2003-12-05 | 2007-01-03 | 拜尔农作物科学股份公司 | Synergistic insecticide mixtures |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54125677A (en) * | 1978-03-17 | 1979-09-29 | Ishihara Sangyo Kaisha Ltd | N-benzoyl-n'-pyridyloxyphenylurea compound,its preparation,and insecticide containing the same |
| JPS5764604A (en) * | 1980-10-08 | 1982-04-19 | Ishihara Sangyo Kaisha Ltd | Exterminating method of fly |
-
2010
- 2010-09-28 CN CN 201010299835 patent/CN102415397B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1112556A (en) * | 1993-10-26 | 1995-11-29 | 三井东压化学株式会社 | Furanyl insecticide |
| CN1889842A (en) * | 2003-12-05 | 2007-01-03 | 拜尔农作物科学股份公司 | Synergistic insecticide mixtures |
Non-Patent Citations (2)
| Title |
|---|
| JP昭54-125677A 1978.09.29 |
| JP昭57-64604A 1982.04.19 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102415397A (en) | 2012-04-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103621535A (en) | Synergistic insect disinfestation composition containing clothianidin and chlorantraniliprole, and application thereof | |
| CN102017992B (en) | Synergistic insecticidal composition containing chlorfluazuron and chlorpyrifos-methyl and application thereof | |
| CN103039457B (en) | Synergistic insecticidal composition containing tolfenpxrad and flubendiamide and application thereof | |
| CN103621546A (en) | Synergistic insecticidal composition containing clothianidin and imidacloprid and applications thereof | |
| CN103053534B (en) | Synergistic insecticidal composition containing tolfenpyrad and chlorantraniliprole and application | |
| CN102415404B (en) | Composite insecticidal composition containing dinotefuran and isoprocarb and purpose thereof | |
| CN102415397B (en) | Synergia insecticide composition containing dinotefuran and chlorfluazuron and application thereof | |
| CN103039500A (en) | Synergistic insecticidal composition containing tolfenpxrad and cyfloxylate and application thereof | |
| CN103053594A (en) | Synergistic insecticidal composition containing tolfenpyrad and theta-cypermethrin and its application | |
| CN103039458A (en) | Insecticidal composition containing tolfenpxrad and pyridalyl and application thereof | |
| CN103651497A (en) | Synergistic insecticidal composition containing clothianidin and flubendiamide and application of synergistic insecticidal composition | |
| CN103039475A (en) | Synergistic insecticidal composition containing tolfenpxrad and chlorfluazuron and application thereof | |
| CN103039456B (en) | Synergistic insecticidal composition containing tolfenpxrad and S-fenvalerate and application thereof | |
| CN102415395A (en) | Composite pesticidal composition containing dinotefuran and imidacloprid and application of composite pesticidal composition | |
| CN103053596A (en) | Synergistic insecticidal composition containing tolfenpyrad and cypermethrin and application | |
| CN103053577A (en) | Synergistic insecticidal composition containing tolfenpyrad and indoxacarb and application | |
| CN103621540B (en) | Synergistic insecticidal composition containing clothianidin and chlorfluazuron and applications thereof | |
| CN103621534B (en) | A kind of Synergistic insecticidal compositions and application thereof containing Diacloden and chlorfluazuron | |
| CN103621538A (en) | Synergistic insecticidal composition containing clothianidin and imidaclothiz and applications thereof | |
| CN103621537A (en) | Synergistic insecticidal composition containing clothianidin and banleptm and applications thereof | |
| CN103563953A (en) | Composite insecticidal composition containing methoxyfenozide and chlorfluazuron and application thereof | |
| CN103039455B (en) | Synergistic insecticidal composition containing tolfenpxrad and flonicamid and application thereof | |
| CN102217645A (en) | Insecticidal composition containing novaluron and organophosphorus compounds | |
| CN102415403B (en) | Composite pesticidal composition containing dinotefuran and MTMC and application thereof | |
| CN103053570A (en) | Synergistic insecticidal composition containing tolfenpyrad and metaflumizone and application |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |