CN102406757A - Traditional Chinese medicine capsule for treating myelodysplastic syndrome and its manufacturing method - Google Patents
Traditional Chinese medicine capsule for treating myelodysplastic syndrome and its manufacturing method Download PDFInfo
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- CN102406757A CN102406757A CN2011103846920A CN201110384692A CN102406757A CN 102406757 A CN102406757 A CN 102406757A CN 2011103846920 A CN2011103846920 A CN 2011103846920A CN 201110384692 A CN201110384692 A CN 201110384692A CN 102406757 A CN102406757 A CN 102406757A
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Abstract
The invention discloses a traditional Chinese medicine capsule for treating myelodysplastic syndrome and its manufacturing method. The traditional Chinese medicine capsule comprises the following raw materials by weight part: 30-50 parts of oldenlandia diffusa, 20-50 parts of herba cephalanoploris, 30-50 parts of buffalo horn powder, 30-50 parts of Radix Astragali, 30-40 parts of donkey-hide gelatin, 30-50 parts of wolfberry, 30-35 parts of placenta hominis, 20-30 parts of turtle shell, 20-30 parts of fleece-flower root, 20-40 parts of epimeddium, 20-25 parts of cortex moutan radicis, 20-30 parts of Chinese angelica, 30-50 parts of spatholobus stem, 6-9 parts of natural indigo, 20-30 parts of rehmanniae radix and 20-30 parts of licorice. The manufacturing method comprises the following steps: crushing the traditional Chinese medicine raw materials according to weight, mixing with processed honey and drying, crushing to powdery state after drying and then filling into the capsule.
Description
Technical field
The present invention relates to the hemopathic medicine of a kind of treatment, particularly a kind of Chinese medicinal capsule of treating myelodysplastic syndrome and preparation method thereof.
Background technology
Myelodysplastic syndrome is a kind of malignant clone property disease of hematopoietic stem cell, reduces being easy to again be converted into characteristic to the leukemia direction with ineffective hematopoiesis, hemocyte dysmaturity and PBC.It is because multiple physics, chemical factor make hematopoietic stem cell impaired like alkylating agent, benzene-like compounds, ionizing radiation etc., causes ineffective hematopoiesis, and then hemogram one occurs and be, two be or three be to reduce and fall ill.The traditional Chinese medical science belongs to categories such as " asthenia ", " blood deficiency ", " blood depletion ".It is slow to be used to treat the myelodysplastic syndrome Progress in Medication in recent years, weak curative effect, and effective percentage is less than 50% at present.Bone marrow transplantation can be cured, but has a big risk, expensive, and most patients can not find donor, are difficult to implement.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicinal capsule of treating myelodysplastic syndrome and preparation method thereof, it has detoxifcation, sets upright, blood stasis dispelling, recovers the function of normal hematopoiesis.
The object of the invention can adopt following technical scheme to realize:
The said Chinese medicinal capsule that is used to treat myelodysplastic syndrome is made up of following raw material of Chinese medicine by weight:
30～50 parts of Herba Hedyotidis Diffusaes, 20～50 parts of Herba Cirsiis, 30～50 parts of Cornu Bubali powders,
30～50 parts of the Radixs Astragali, 30～40 parts in Colla Corii Asini, 30～50 parts of Fructus Lycii, 30～35 parts of Placenta Hominiss,
20～30 parts of Carapax Trionycis, 20～30 parts of Radix Polygoni Multiflori, 20～40 parts of Herba Epimedii, 20～25 parts of Cortex Moutans, 20～30 parts of Radix Angelicae Sinensis, 30～50 parts of Caulis Spatholobis, 6～9 parts of Indigo Naturaliss, 20～30 parts in the Radix Rehmanniae,
20～30 parts in Radix Glycyrrhizae.
The manufacture method of said Chinese medicine: above-mentioned raw material of Chinese medicine is pulverized, is mixed the back with the good Mel of refining then and dry, after the oven dry again the comminuted powder powder incapsulate.
Raw material foundation of the present invention
Chinese medicine research shows in the important source material of the present invention, and wherein Herba Hedyotidis Diffusae has the effect of heat-clearing and toxic substances removing, and bitter but sweet flavor is cold in nature.
Herba Cirsii: the sweet cold of nature and flavor is nontoxic, has the effect of removing heat from blood, blood stasis dispelling, hemostasis.
Cornu Bubali powder: nature and flavor bitter cold.Effect with heat-clearing and toxic substances removing and cooling blood for hemostasis.
The Radix Astragali: the sweet tepor of nature and flavor has the effect of qi-supplementing, blood-engendering.
Colla Corii Asini: nature and flavor are sweet, have the removing heat from blood of enriching blood, the effect of lung moistening YIN nourishing.
Fructus Lycii: the property sugariness is flat, has nourishing liver and stomach, the effect of blood-enriching tranquillizing.
Placenta Hominis: sweet in the mouth warm in nature has the kidney warming and mends essence, the effect of benefiting QI and nourishing blood.
Carapax Trionycis: salty in the mouth property is flat, has nourishing YIN for suppressing the hyperactive YANG, brings down a fever and removes the effect of steaming.
Radix Polygoni Multiflori: sweet in the mouth, puckery, slightly warm in nature, ability invigorating the liver and kidney, benefiting essence-blood.
Herba Epimedii: nature and flavor are hot, sweet, warm.Can beneficial vital essence.
Cortex Moutan: cold in nature, bitter in the mouth.Have clearing away heat and cooling blood, control the effect of blood dissipating blood stasis.
Radix Angelicae Sinensis: sweet in the mouth is hot, and is warm in nature.The effect that having enriches blood invigorates blood circulation.
Caulis Spatholobi: nature and flavor are bitter, sweet, warm.Have enrich blood, the effect of promoting blood circulation to remove obstruction in the collateral.
Indigo Naturalis: bitter in the mouth, cold in nature, nontoxic.Effect with clearing away heat,cooling blood and removing toxin.
The Radix Rehmanniae: sweet-bitter flavor, cold in nature.Effect with clearing away heat and cooling blood.
Radix Glycyrrhizae: nature and flavor are sweet flat.Has invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, the effect of mediation principal agent.
The present invention forms through long-term clinical practice research, and according to " pyretic toxicity, all empty, blood stasis " pathogenesis of myelodysplastic syndrome, the medicine of employing has clearing away heat,cooling blood and removing toxin, holds up revisal gas; Be used for human body immunity improving power, antitoxin eliminating evil, suppress DH; Suppress neoplasm; Suppress the excessive apoptosis of hematopoietic cell, recover normal hematopoiesis, the quality of making the life better.Hold concurrently with blood circulation promoting and blood stasis dispelling, unobstructed blood vessels help detoxifcation, help the recovery of disease.
Medicine of the present invention was used to treat myelodysplastic syndrome case 120 examples in 3 years, and total effective rate reaches about 70%, and the treatment standard is pressed " hematopathy diagnosis and the criterion of therapeutical effect " third edition one book of Zhang Zhinan chief editor.After most patients took January, blood picture improved, and condition of illness alleviates, and postponed or stop transforming to the leukemia direction.
The specific embodiment
Embodiment 1: described Chinese medicinal capsule is made up of following raw material of Chinese medicine by weight:
35 parts of Herba Hedyotidis Diffusaes, 30～50 parts of Herba Cirsiis, 35 parts of Cornu Bubali powders, 35 parts of the Radixs Astragali, 30 parts in Colla Corii Asini, 35 parts of Fructus Lycii; 30 parts of Placenta Hominiss, 20 parts of Carapax Trionycis, 20 parts of Radix Polygoni Multiflori, 25 parts of Herba Epimedii, 20 parts of Cortex Moutans; 20 parts of Radix Angelicae Sinensis, 35 parts of Caulis Spatholobis, 6 parts of Indigo Naturaliss, 20 parts in the Radix Rehmanniae, 20 parts in Radix Glycyrrhizae.
Manufacture method: above-mentioned raw material of Chinese medicine is pulverized, mixed the back oven dry with the good Mel of refining then, be ground into Powdered incapsulating after the oven dry again.
Embodiment 2: described Chinese medicinal capsule is made up of following raw material of Chinese medicine by weight:
40 parts of Herba Hedyotidis Diffusaes, 40 parts of Herba Cirsiis, 40 parts of Cornu Bubali powders, 40 parts of the Radixs Astragali, 35 parts in Colla Corii Asini, 40 parts of Fructus Lycii; 32 parts of Placenta Hominiss, 25 parts of Carapax Trionycis, 25 parts of Radix Polygoni Multiflori, 30 parts of Herba Epimedii, 22 parts of Cortex Moutans; 25 parts of Radix Angelicae Sinensis, 40 parts of Caulis Spatholobis, 7 parts of Indigo Naturaliss, 25 parts in the Radix Rehmanniae, 25 parts in Radix Glycyrrhizae.
Manufacture method: above-mentioned raw material of Chinese medicine is pulverized, mixed the back oven dry with the good Mel of refining then, be ground into Powdered incapsulating after the oven dry again.
Embodiment 3: described Chinese medicinal capsule is made up of following raw material of Chinese medicine by weight:
45 parts of Herba Hedyotidis Diffusaes, 45 parts of Herba Cirsiis, 45 parts of Cornu Bubali powders, 45 parts of the Radixs Astragali, 37 parts in Colla Corii Asini, 45 parts of Fructus Lycii, 35 parts of Placenta Hominiss, 30 parts of Carapax Trionycis, 30 parts of Radix Polygoni Multiflori, 35 parts of Herba Epimedii, 25 parts of Cortex Moutans, 30 parts of Radix Angelicae Sinensis, 45 parts of Caulis Spatholobis, 8 parts of Indigo Naturaliss, 30 parts in the Radix Rehmanniae,
20～30 parts in Radix Glycyrrhizae.
Manufacture method: above-mentioned raw material of Chinese medicine is pulverized, mixed the back oven dry with the good Mel of refining then, be ground into Powdered incapsulating after the oven dry again.
Claims (5)
1. Chinese medicinal capsule of treating myelodysplastic syndrome is characterized in that being made up of following raw material of Chinese medicine by weight:
30～50 parts of Herba Hedyotidis Diffusaes, 20～50 parts of Herba Cirsiis, 30～50 parts of Cornu Bubali powders,
30～50 parts of the Radixs Astragali, 30～40 parts in Colla Corii Asini, 30～50 parts of Fructus Lycii, 30～35 parts of Placenta Hominiss,
20～30 parts of Carapax Trionycis, 20～30 parts of Radix Polygoni Multiflori, 20～40 parts of Herba Epimedii, 20～25 parts of Cortex Moutans, 20～30 parts of Radix Angelicae Sinensis, 30～50 parts of Caulis Spatholobis, 6～9 parts of Indigo Naturaliss, 20～30 parts in the Radix Rehmanniae,
20～30 parts in Radix Glycyrrhizae.
2. the Chinese medicinal capsule of treatment myelodysplastic syndrome according to claim 1 is characterized in that said raw material of Chinese medicine consisting of by weight: 35 parts of Herba Hedyotidis Diffusaes, 30～50 parts of Herba Cirsiis, 35 parts of Cornu Bubali powders, 35 parts of the Radixs Astragali; 30 parts in Colla Corii Asini, 35 parts of Fructus Lycii, 30 parts of Placenta Hominiss, 20 parts of Carapax Trionycis; 20 parts of Radix Polygoni Multiflori, 25 parts of Herba Epimedii, 20 parts of Cortex Moutans, 20 parts of Radix Angelicae Sinensis; 35 parts of Caulis Spatholobis, 6 parts of Indigo Naturaliss, 20 parts in the Radix Rehmanniae, 20 parts in Radix Glycyrrhizae.
3. the Chinese medicinal capsule of treatment myelodysplastic syndrome according to claim 1 is characterized in that said raw material of Chinese medicine consisting of by weight: 40 parts of Herba Hedyotidis Diffusaes, 40 parts of Herba Cirsiis, 40 parts of Cornu Bubali powders, 40 parts of the Radixs Astragali; 35 parts in Colla Corii Asini, 40 parts of Fructus Lycii, 32 parts of Placenta Hominiss, 25 parts of Carapax Trionycis; 25 parts of Radix Polygoni Multiflori, 30 parts of Herba Epimedii, 22 parts of Cortex Moutans, 25 parts of Radix Angelicae Sinensis; 40 parts of Caulis Spatholobis, 7 parts of Indigo Naturaliss, 25 parts in the Radix Rehmanniae, 25 parts in Radix Glycyrrhizae.
4. the Chinese medicinal capsule of treatment myelodysplastic syndrome according to claim 1 is characterized in that said raw material of Chinese medicine consisting of by weight: 45 parts of Herba Hedyotidis Diffusaes, 45 parts of Herba Cirsiis, 45 parts of Cornu Bubali powders, 45 parts of the Radixs Astragali; 37 parts in Colla Corii Asini, 45 parts of Fructus Lycii, 35 parts of Placenta Hominiss, 30 parts of Carapax Trionycis; 30 parts of Radix Polygoni Multiflori, 35 parts of Herba Epimedii, 25 parts of Cortex Moutans, 30 parts of Radix Angelicae Sinensis; 45 parts of Caulis Spatholobis, 8 parts of Indigo Naturaliss, 30 parts in the Radix Rehmanniae, 20～30 parts in Radix Glycyrrhizae.
5. according to the manufacture method of the Chinese medicinal capsule of claim 1 or 2 or the 3 or 4 said treatment myelodysplastic syndromes of controlling; It is characterized in that: will pulverize according to the raw material of Chinese medicine that weight portion is formed; Mixes the back with the good Mel of refining then and dries, after the oven dry again the comminuted powder powder incapsulate.
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| WO2009088572A2 (en) * | 2008-01-07 | 2009-07-16 | Centocor, Inc. | Method of treating erythropoietin hyporesponsive anemias |
| US20110097343A1 (en) * | 2009-10-26 | 2011-04-28 | Djordje Atanackovic | Diagnosis and therapy of hematological malignancies |
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| EA001862B1 (en) * | 1996-07-01 | 2001-10-22 | Шелл Интернэшнл Рисерч Маатсхаппий Б.В. | Electrical logging of a laminated earth formation |
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Patent Citations (8)
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|---|---|---|---|---|
| CN1092988A (en) * | 1993-04-02 | 1994-10-05 | 包鸿廷 | The leukemic Chinese medicine of a kind of treatment |
| CN1137393A (en) * | 1995-06-08 | 1996-12-11 | 孟涛 | Yisuishengxue Chinese medicine preparation for tonifying marrow and promoting generation of blood |
| CN1062144C (en) * | 1995-06-08 | 2001-02-21 | 孟涛 | Yisuishengxue chinese medicine preparation for tonifying marrow and promoting generation of blood |
| CN1160560A (en) * | 1996-03-21 | 1997-10-01 | 廖柏松 | Chinese patent drug for curing leukopenia and its preparation process |
| JPH11343242A (en) * | 1998-03-30 | 1999-12-14 | Otsuka Pharmaceut Co Ltd | Transplantation agent for hematopoietic stem cell |
| CN101199748A (en) * | 2007-12-05 | 2008-06-18 | 李其孟 | Chinese medicine preparation for treating hematonosis |
| WO2009088572A2 (en) * | 2008-01-07 | 2009-07-16 | Centocor, Inc. | Method of treating erythropoietin hyporesponsive anemias |
| US20110097343A1 (en) * | 2009-10-26 | 2011-04-28 | Djordje Atanackovic | Diagnosis and therapy of hematological malignancies |
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| 许云: "正源养荣方治疗骨髓增生异综合征的临床研究", 《中国优秀硕士论文数据库》 * |
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