CN102406704B - Chinese medicinal preparation for treating ankylosing spondylitis - Google Patents
Chinese medicinal preparation for treating ankylosing spondylitis Download PDFInfo
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- CN102406704B CN102406704B CN2011103866591A CN201110386659A CN102406704B CN 102406704 B CN102406704 B CN 102406704B CN 2011103866591 A CN2011103866591 A CN 2011103866591A CN 201110386659 A CN201110386659 A CN 201110386659A CN 102406704 B CN102406704 B CN 102406704B
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- chinese medicinal
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- ankylosing spondylitis
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- 206010002556 Ankylosing Spondylitis Diseases 0.000 title claims abstract description 15
- 238000002360 preparation method Methods 0.000 title claims abstract description 15
- 239000002994 raw material Substances 0.000 claims abstract description 6
- 239000003814 drug Substances 0.000 claims description 8
- 235000003143 Panax notoginseng Nutrition 0.000 claims description 4
- 241000180649 Panax notoginseng Species 0.000 claims description 4
- 230000000694 effects Effects 0.000 abstract description 12
- 208000002193 Pain Diseases 0.000 abstract description 7
- 230000017531 blood circulation Effects 0.000 abstract description 6
- 210000003734 kidney Anatomy 0.000 abstract description 5
- 201000010099 disease Diseases 0.000 abstract description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 4
- 210000004185 liver Anatomy 0.000 abstract description 4
- 230000001737 promoting effect Effects 0.000 abstract description 4
- 210000002435 tendon Anatomy 0.000 abstract description 4
- 230000001717 pathogenic effect Effects 0.000 abstract description 2
- 238000005728 strengthening Methods 0.000 abstract description 2
- 241001233914 Chelidonium majus Species 0.000 abstract 1
- 241000125184 Heracleum Species 0.000 abstract 1
- 241000488974 Loranthus Species 0.000 abstract 1
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 235000003181 Panax pseudoginseng Nutrition 0.000 abstract 1
- 241000270273 Ptyas dhumnades Species 0.000 abstract 1
- 235000017276 Salvia Nutrition 0.000 abstract 1
- 240000007164 Salvia officinalis Species 0.000 abstract 1
- 229940107131 ginseng root Drugs 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 230000003071 parasitic effect Effects 0.000 abstract 1
- 239000008280 blood Substances 0.000 description 19
- 210000004369 blood Anatomy 0.000 description 19
- 210000003205 muscle Anatomy 0.000 description 11
- 239000000047 product Substances 0.000 description 6
- 208000024891 symptom Diseases 0.000 description 6
- 208000006820 Arthralgia Diseases 0.000 description 5
- 210000000988 bone and bone Anatomy 0.000 description 4
- 239000012567 medical material Substances 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 208000025747 Rheumatic disease Diseases 0.000 description 3
- 206010003549 asthenia Diseases 0.000 description 3
- 238000002651 drug therapy Methods 0.000 description 3
- 230000005906 menstruation Effects 0.000 description 3
- 231100000862 numbness Toxicity 0.000 description 3
- 230000000552 rheumatic effect Effects 0.000 description 3
- 206010010904 Convulsion Diseases 0.000 description 2
- 230000003213 activating effect Effects 0.000 description 2
- 210000001367 artery Anatomy 0.000 description 2
- 230000036461 convulsion Effects 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 239000000706 filtrate Substances 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 229940126701 oral medication Drugs 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 230000002040 relaxant effect Effects 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- 208000008035 Back Pain Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010033425 Pain in extremity Diseases 0.000 description 1
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- 230000000202 analgesic effect Effects 0.000 description 1
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- 239000003908 antipruritic agent Substances 0.000 description 1
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- 208000019804 backache Diseases 0.000 description 1
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- 230000001684 chronic effect Effects 0.000 description 1
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- 230000035619 diuresis Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
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- 210000003414 extremity Anatomy 0.000 description 1
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- 230000035876 healing Effects 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
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- 208000037920 primary disease Diseases 0.000 description 1
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Abstract
The invention belongs to the field of Chinese medicinal preparations and particularly relates to a Chinese medicinal preparation for treating ankylosing spondylitis. The Chinese medicinal preparation is prepared from the following raw materials in part by weight: 3 parts of heracleum, 3 parts of caulis spatholobi, 4 parts of parasitic loranthus, 1 part of pseudo-ginseng root, 3 parts of root of red-rooted salvia, 2 parts of herba lycopi, 1 part of zaocys dhumnade and 2 parts of paniculate swallowwort root. The Chinese medicinal preparation has the effects of tonifying the liver and kidney, strengthening tendons and nourishing the kidney; and when the Chinese medicinal preparation used for treating ankylosing spondylitis, the effectiveness is quick, the treatment effect is high, the disease is cured without heating healthy qi, and tonifying is performed without leaving pathogenic factor. The Chinese medicinal preparation has the characteristics of clearing channels, promoting qi and blood circulation and relieving pain.
Description
Technical field
The invention belongs to field of traditional Chinese, particularly a kind of Chinese medicine preparation for the treatment of ankylosing spondylitis.
Background technology
Ankylosing spondylitis is a kind of chronic progressive external systemic disease, the traditional Chinese medical science thinks that ankylosing spondylitis is due to the body imbalance of YIN and YANG, healthy energy is not solid, affection of exogenous wind-cold, wet, hot heresy, impatency meridians, QI and blood numbness hinder, the pathogen heat-transformation causes deficiency of kidney-QI, essence and blood loses, joint muscle arteries and veins loses and supports and fall ill, and Early manifestation is that backache and back are tetanic clinically, mainly invades sacroiliac joint, often cause muscle, bones and muscles pain, numbness, weighing, joint stuffiness, arthroncus, the symptom such as scorching hot.The main pathogenesis of primary disease is that blood and essence asthenia, muscle arteries and veins lose and support, and by dialectical, the treatment rule such as takes liver and kidney tonifying, strong muscle to support to superintend and direct obtained effect preferably clinically.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of Chinese medicine preparation for the treatment of ankylosing spondylitis, has that determined curative effect, cure rate are high, a safe ready, the characteristics that have no side effect.
A kind of Chinese medicine preparation for the treatment of ankylosing spondylitis of the present invention is characterized in that being made by the raw material of Chinese medicine of following parts by weight: 2 parts of 3 parts of Radix Angelicae Pubescentiss, 3 parts of Caulis Spatholobis, 4 parts of Herba Taxillis, 1 part of Radix Notoginseng, 3 parts of Radix Salviae Miltiorrhizaes, 2 parts of Herba Lycopi, 1 part of Zaocys and Radix Cynanchi Paniculatis.
The present invention can make acceptable various preparations on Chinese materia medica, preferably decoction.
Preparation method: take raw material by above-mentioned weight, put in multi-function extractor and decoct with water secondary, add up for the first time the water of medical material octuple weight, decoct two hours, get decocting liquid; The decocting that adds up for the second time five times of weight of medical material boils one hour, filters; Twice filtrate is mixed, in the heat-sealing bag, 100 ℃ of high temperature sterilizes, every bag of 200ml.
Usage and consumption: oral, every day, sooner or later respectively once each one bag 30 days was a course for the treatment of.
Drug action mechanism of the present invention is as follows:
Radix Angelicae Pubescentis: wind-damp dispelling, stopping numbness pain, induce sweat, be usually used in clinically rheumatic arthralgia, its property of this product is kind descending, especially with waist knee joint, joints of foot pain subordinate section cold-damp, is weighing and is being advisable.
Caulis Spatholobi: promoting the circulation of blood is enriched blood, regulating menstruation, relaxing muscles and tendons and activating QI and blood in the collateral, this product can be enriched blood and can be invigorated blood circulation, all applicable to the disease of blood stasis, blood deficiency, therefore be usually used in clinically rheumatic arthralgia and numb hand and foot person, this product can nourish blood, invigorate blood circulation and relaxing muscles and tendons and activating QI and blood in the collateral, is the good merchantable brand for the treatment of rheumatic arthralgia, arthralgia, numb limbs and tense tendons.
Herba Taxilli: wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening, antiabortive.
Radix Notoginseng: removing stasis to stop bleeding, the analgesic therapy of invigorating blood circulation, this product can be stopped blooding and can dissipating blood stasis, and hemostasis does not stay the stasis of blood, blood stasis dispelling just not to hinder.
Radix Salviae Miltiorrhizae: promoting blood flow to regulate menstruation, removing heat from blood disappear bitterly, calm the nerves.
Herba Lycopi: blood circulation promoting and blood stasis dispelling, regulating menstruation, inducing diuresis to remove edema.
Zaocys: dispelling wind and removing obstruction in the collateral, arresting convulsion relieving convulsion, this product can be searched ailment said due to cold or exposure, saturating joint, controls the slow migratory arthralgia that can not stretch act of brothers.
Radix Cynanchi Paniculati: wind-expelling pain-stopping, antipruritic, this product has wind-expelling pain-stopping effect preferably, is usually used in the various pain due to rheumatism, cold coagulation, qi stagnation blood stasis.
The curative effect judgement:
The basic healing: subjective symptoms disappears, and spinal column is movable recovers normal substantially, and lab testing is normal, and the lumbar X sheet shows that curvature is normal.
Take a turn for the better: symptom disappears substantially, and relevant chemical examination is normal, the function normal, and it is normal that x-ray checks that lumbar curvature approaches.
Invalid: symptom is without improvement.
Therapeutic outcome:
Treatment patients with ankylosing spondylitis 80 examples, medicine of the present invention is decoction, oral, each one bag, a twice-daily, 30 days be a course for the treatment of.Substantially cure 50 examples through three course of therapy, basic cure rate 62%, 19 examples that take a turn for the better, improvement rate 24%, invalid 11 examples, account for 14%, total effective rate 86%.Shown in treatment, without any side effects to patient, three large routine tests and hepatic and renal function detect no abnormal phenomenon.
Below enumerate several model cases:
Case 1: patient Zhang, the man, 56 years old, suffer from ankylosing spondylitis more than 3 years, multi-treatment is invalid, and examine in October, 2008, oral administration Drug therapy of the present invention transference cure after three courses for the treatment of, the movable normal of spinal column, the X sheet shows that lumbar curvature is normal, follows up a case by regular visits to and does not increase the weight of in 1 year.
Case 2: the patient appoints certain, the man, 50 years old, suffer from ankylosing spondylitis more than 1 year, oral Drug therapy of the present invention after three courses for the treatment of symptom substantially disappear, spinal column is movable normal, the X sheet shows that lumbar curvature is normal, follows up a case by regular visits to and does not increase the weight of in 1 year.
Case 3: patient Yang, the man, 42 years old, the year before because of the back limitation of activity, tetanic pain, examined as ankylosing spondylitis, oral Drug therapy of the present invention after three courses for the treatment of symptom substantially disappear, activity freely, is followed up a case by regular visits to and is not increased the weight of in 1 year.
The present invention has the following advantages:
(1) Chinese herbal medicine used in the present invention all meets the Pharmacopoeia of People's Republic of China regulation, and according to compatibility, the present invention has invigorating the liver and kidney, strong muscle is supported the effect of superintending and directing, and mainly is applicable to clinically blood and essence asthenia, the foster type of muscles and bones mistake for wanting.
(2) the present invention not only has good therapeutical effect to ankylosing spondylitis (blood and essence asthenia, muscles and bones mistake are supported type), and the prevention of this disease is also had to good effect.
(3) the present invention is nontoxic, harmless, and prescription is rigorous, science, efficient, the characteristics of have instant effect, short treating period, taking convenience, easily by the patient, being accepted.
The specific embodiment
Below in conjunction with embodiment, the present invention is described further.
Embodiment
Take by weight raw material: 2 parts of 3 parts of Radix Angelicae Pubescentiss, 3 parts of Caulis Spatholobis, 4 parts of Herba Taxillis, 1 part of Radix Notoginseng, 3 parts of Radix Salviae Miltiorrhizaes, 2 parts of Herba Lycopi, 1 part of Zaocys and Radix Cynanchi Paniculatis.
Preparation method: take raw material by above-mentioned weight, put in multi-function extractor and decoct with water secondary, add up for the first time the water of medical material octuple weight, decoct two hours, get decocting liquid, the decocting that adds up for the second time five times of weight of medical material boils one hour, filters; Twice filtrate is mixed, in the heat-sealing bag, 100 ℃ of high temperature sterilizes, every bag of 200ml.
Claims (1)
1. a Chinese medicine preparation for the treatment of ankylosing spondylitis is characterized in that being made by the raw material of following parts by weight: 2 parts of 3 parts of Radix Angelicae Pubescentiss, 3 parts of Caulis Spatholobis, 4 parts of Herba Taxillis, 1 part of Radix Notoginseng, 3 parts of Radix Salviae Miltiorrhizaes, 2 parts of Herba Lycopi, 1 part of Zaocys and Radix Cynanchi Paniculatis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011103866591A CN102406704B (en) | 2011-11-29 | 2011-11-29 | Chinese medicinal preparation for treating ankylosing spondylitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011103866591A CN102406704B (en) | 2011-11-29 | 2011-11-29 | Chinese medicinal preparation for treating ankylosing spondylitis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102406704A CN102406704A (en) | 2012-04-11 |
| CN102406704B true CN102406704B (en) | 2013-12-11 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011103866591A Expired - Fee Related CN102406704B (en) | 2011-11-29 | 2011-11-29 | Chinese medicinal preparation for treating ankylosing spondylitis |
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| Country | Link |
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| CN (1) | CN102406704B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103768145B (en) * | 2014-02-21 | 2016-08-24 | 中国人民解放军第三军医大学第二附属医院 | The Chinese medicine preparation for the treatment of ankylosing spondylitis |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101085131A (en) * | 2007-06-20 | 2007-12-12 | 济南新境界企业管理咨询有限公司 | Internal-applied traditional Chinese medicine for treating rigid spine inflammation |
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- 2011-11-29 CN CN2011103866591A patent/CN102406704B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101085131A (en) * | 2007-06-20 | 2007-12-12 | 济南新境界企业管理咨询有限公司 | Internal-applied traditional Chinese medicine for treating rigid spine inflammation |
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| Publication number | Publication date |
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| CN102406704A (en) | 2012-04-11 |
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| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: HAIMEN LINJIANG BIO-PARMACEUTICAL TECHNOLOGY AND I Free format text: FORMER OWNER: SONG AIMIN Effective date: 20140409 |
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| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 256100 ZIBO, SHANDONG PROVINCE TO: 226133 NANTONG, JIANGSU PROVINCE |
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| TR01 | Transfer of patent right |
Effective date of registration: 20140409 Address after: 226133, Nantong, Jiangsu Province Linjiang New District Linjiang Industrial Park Patentee after: Haimen Linjiang biological medicine science and Technology Pioneer Park Co Ltd Address before: 256100 Yiyuan people's Hospital, Zibo, Shandong, China Patentee before: Song Aimin |
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| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20131211 Termination date: 20181129 |