CN102406177A - Health product used for supporting strong bones - Google Patents

Health product used for supporting strong bones Download PDF

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CN102406177A
CN102406177A CN2011103052273A CN201110305227A CN102406177A CN 102406177 A CN102406177 A CN 102406177A CN 2011103052273 A CN2011103052273 A CN 2011103052273A CN 201110305227 A CN201110305227 A CN 201110305227A CN 102406177 A CN102406177 A CN 102406177A
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health products
oyster
bone
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CN102406177B (en
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苏洋
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Nantong good and fresh aquatic food Co., Ltd.
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Abstract

The invention provides a health product used for supporting strong bones. The health product is composed of oyster, rhodiola rosea, pumpkin seed, pepper, capsicum, soybean isoflavone, vitamin D, and fish collagen peptide. The health product provided by the invention has the advantages of improving immune system, resisting fatigue, and resisting senium; and the health product is contributed to strengthening the muscle and bone, tonifying the kidney and controlling nocturnal emission, and delaying senium.

Description

A kind of health products of strong bone
Technical field
The present invention relates to a kind of health products, specifically, relating to a kind of is the product that raw material is processed by oyster, rhodiola root, pumpkin seeds, Chinese prickly ash, capsicum, isoflavones, vitamin D, Isin glue collagen.
Background technology
Osteoporosis is a kind of systemic osteopathy; It is characterized in that the bone amount descends and the fine structure of bone destroys, bone ore deposit composition and bone matrix equal proportion ground constantly reduce the sclerotin attenuation; Bone trabecula quantity reduces, the disease of a kind of whole body dysostosis that increase of bone fragility and risk of fractures degree raise.Thereby the fracture danger greatly increase, even also fracture easily under slight wound or the atraumatic situation.Osteoporosis is a kind of chronic disease due to multifactor.Before fracture takes place, there is not special clinical manifestation usually.The women is more than the male sex for this disease, is common in postmenopausal women and the elderly.Along with the increase of China's elderly population, the osteoporosis incidence of disease is in ascendant trend, all is a health problem that merits attention in the China and even the whole world.
Modal senile osteoporosis is the increase along with the age, and the hormone in vivo level descends, due to bone absorption increases.Morbidity is many relatively slowly, and is indivedual very fast, with skeleton pain, to be easy to fracture be characteristic.Patient whole body ostalgia is main with vertebra, pelvic region and fracture, be persistent ache, and parallel with the osteoporosis degree, when pedaling building or Body Position Change more so.The atrophy of prolonged illness lower limb muscles, vertebral compression fracture, dedicate one's life to is long to be shortened; Chest deformity, lung capacity reduces, serious influenced cardio-pulmonary function.The medicine that the medicine of present Prevention and Treatment of Osteoporosis mainly contains female treatment osteoporosis has following five kinds:
The hormone replacement therapy: estrogen adds lutern.Alendronate: suppress the effect of osteoclast.Calcitonin: borrowing subcutaneous, intramuscular injection or nostril to absorb, the osteoporosis women more than 5 years is effective for menelipsis.4. calcium agent and vitamin D: the drug combination effect is better.5. bone peptide preparation.
Wherein estrogen is longer medicine time, possibly cause breast cancer and carcinoma of endometrium simultaneously, and the prolonged application toxic and side effect is bigger.Calcitonin has certain curative effect to osteoporosis, but costs an arm and a leg, and is difficult to accept for extensive patients.
The anti-fracture of old man must increase bone toughness; At present, various many on the market to middle-aged and old health food and medicines of replenishing the calcium, but be mostly the single product of replenishing the calcium or replenishing the calcium and combining with microelement-supplementing; The treatment osteoporosis; Should replenish calcium and collagen simultaneously, let calcium in the bonding deposit of collagen in bone, greatly strengthen the toughness and the hardness of bone.
Summary of the invention
The health products that the purpose of this invention is to provide a kind of strong bone.
A kind of health products comprise following raw materials according: oyster, rhodiola root.
A kind of health products of strong bone are made up of following raw materials according: oyster 60-200 gram, rhodiola root 40-100 gram, pumpkin seeds 20-80 gram, Chinese prickly ash 2-4 gram, capsicum 1-2 gram, isoflavones 1-2 gram, vitamin D 1-2 gram, Isin glue collagen 1-2 gram.
A kind of health products of strong bone are made up of following raw materials according: oyster 60 grams, rhodiola root 40 grams, pumpkin seeds 20 grams, Chinese prickly ash 2 grams, capsicum 1 gram, isoflavones 1 gram, vitamin D 1 gram, Isin glue collagen 1 gram.
A kind of health products of strong bone are made up of following raw materials according: oyster 200 grams, rhodiola root 100 grams, pumpkin seeds 80 grams, Chinese prickly ash 4 grams, capsicum 2 grams, isoflavones 2 grams, vitamin D 2 grams, Isin glue collagen 2 grams.
A kind of preparation method of health products of strong bone, each raw meal are broken into 80 order fine powders; With 75% alcohol extract 3 times, merging filtrate, concentrate, vacuum drying is pulverized.
A kind of preparation method of health products of strong bone is a content with xeraphium, microcrystalline cellulose, lactose, starch mixing, processes in the capsulae vacuus of packing into.
A kind of preparation method of health products of strong bone is a content with xeraphium 1-5 gram, microcrystalline cellulose 5-50 gram, lactose 1-10 gram, starch 2-20 gram mixing, processes in the capsulae vacuus of packing into.
A kind of preparation method of health products of strong bone is with xeraphium, microcrystalline cellulose, lactose, starch, dolomol system particle, compressing tablet.
A kind of preparation method of health products of strong bone, with xeraphium 1-5 gram, starch 1-10 gram, lactose 2-20 gram, microcrystalline cellulose 5-50 gram, dolomol 0.4-4 gram is processed 20 purpose particles with above raw material, is pressed into tablet.
The specific embodiment
Embodiment 1
A kind of health products of strong bone are made up of following raw materials according: oyster 60 grams, rhodiola root 40 grams, pumpkin seeds 20 grams, Chinese prickly ash 2 grams, capsicum 1 gram, isoflavones 1 gram, vitamin D 1 gram, Isin glue collagen 1 gram.
Embodiment 2
A kind of health products of strong bone are made up of following raw materials according: oyster 200 grams, rhodiola root 100 grams, pumpkin seeds 80 grams, Chinese prickly ash 4 grams, capsicum 2 grams, isoflavones 2 grams, vitamin D 2 grams, Isin glue collagen 2 grams.
Embodiment 3
A kind of health products of strong bone are made up of following raw materials according: oyster 60 grams, rhodiola root 40 grams, pumpkin seeds 20 grams, Chinese prickly ash 2 grams, capsicum 1 gram, isoflavones 1 gram, vitamin D 1 gram, Isin glue collagen 1 gram.Each raw meal is broken into 80 order fine powders; With 75% alcohol extract 3 times, merging filtrate, concentrate drying.
With xeraphium 1g, microcrystalline cellulose 5g, lactose 1g, starch 2g mixing is content, processes in the capsulae vacuus of packing into.
Embodiment 4
A kind of health products of strong bone are made up of following raw materials according: oyster 200 grams, rhodiola root 100 grams, pumpkin seeds 80 grams, Chinese prickly ash 4 grams, capsicum 2 grams, isoflavones 2 grams, vitamin D 2 grams, Isin glue collagen 2 grams.Each raw meal is broken into 80 order fine powders; With 75% alcohol extract 3 times, merging filtrate, concentrate drying.
With xeraphium 5 grams, microcrystalline cellulose 50 grams, lactose 10 grams, starch 20 gram mixings is content, processes in the capsulae vacuus of packing into.
Embodiment 5
A kind of health products of strong bone are made up of following raw materials according: oyster 60 grams, rhodiola root 40 grams, pumpkin seeds 20 grams, Chinese prickly ash 2 grams, capsicum 1 gram, isoflavones 1 gram, vitamin D 1 gram, Isin glue collagen 1 gram.Each raw meal is broken into 80 order fine powders; With 75% alcohol extract 3 times, merging filtrate, concentrate drying.
With xeraphium 1 gram, starch 1 gram, lactose 3 grams, microcrystalline cellulose 8 grams, dolomol 0.4 gram is processed 20 purpose particles, compressing tablet on special-purpose tablet press machine with above raw material.
Embodiment 6
A kind of health products of strong bone are made up of following raw materials according: oyster 200 grams, rhodiola root 100 grams, pumpkin seeds 80 grams, Chinese prickly ash 4 grams, capsicum 2 grams, isoflavones 2 grams, vitamin D 2 grams, Isin glue collagen 2 grams.Each raw meal is broken into 80 order fine powders; With 75% alcohol extract 3 times, merging filtrate, concentrate drying.
With xeraphium 5 grams, microcrystalline cellulose 50 grams, lactose 10 grams, starch 20 grams, dolomol 4 grams are processed 20 purpose particles with above raw material, are pressed into tablet.
Embodiment 7
With the capsule of embodiment 4, choose male 10 people, women 10 people, 65 years old mean age, every day, everyone took 4, took 2 months, calculated 10 gram/kilograms according to the crude drug amount.Total effective rate 85%.
From intending the treatment standard
Recovery from illness: after treatment, recover.8 people
Produce effects: after treatment, soreness and weakness of waist and knees obviously reduces, and the cramp phenomenon obviously reduces, and the bone density index is obviously recovered, and immunity strengthens.7 people take a turn for the better: after treatment, soreness and weakness of waist and knees reduces, and the cramp phenomenon does not reduce, and the bone density index is recovered a little, and immunity does not strengthen.2 people are invalid: after treatment, soreness and weakness of waist and knees does not reduce, and the cramp phenomenon does not reduce, and the bone density index is not recovered, and immunity does not strengthen.3 people.
Embodiment 8
Capsule preparation method thereof with embodiment 4 obtains dried powder.
Adopt 40 of female rats, be divided into 4 groups at random, establish osteoporosis model group (with reference to the pharmacology test handbook), calcium carbonate group, embodiment 4 high dose group, embodiment 4 low dose group that spay causes.
After every rat is used 1% yellow Jackets (0.4ml/100g) intraperitoneal injection of anesthesia respectively, open the abdominal cavity along the lower abdomen median line, complete excision bilateral ovaries, thoroughly the hemostasis back divides 2 layered sutures to close the abdominal cavity, and postoperative 5d takes out stitches.Back two treated animals of taking out stitches were fed 3 months according to DIFFERENT FEED under same feeding environment:
Embodiment 4 high dose group: basal feed+embodiment 4 high dose group, calculate 4 gram/kilograms according to the crude drug amount;
Embodiment 4 low dose group: basal feed+embodiment 4 low dose group, calculate 1 gram/kilogram according to the crude drug amount;
Calcium carbonate group: basal feed+calcium carbonate.
The osteoporosis model control group: basal feed,
More than four groups fed for 6 weeks, sacrificed by decapitation animal when experiment finishes is got femur and measures bone density.
The result; Experimental group bone calcium, bone density, BMC all are higher than control group; Wherein embodiment 4 high dose group, embodiment 4 low dose group bone densities and control group otherness highly significant (P<0.01), it is obvious that illustrative embodiment 4 has the effect of the osteoporosis of improvement.Be to control osteoporotic safe and effective health food.
4 groups of contrasts (average plus-minus standard deviation) that osteoporosis rat improves
Figure BDA0000097592810000041
*: compare with model group, there is significant difference p<0.05
&: compare with the calcium carbonate group, there is significant difference p<0.05.

Claims (8)

1. health products is characterized in that, comprise following raw materials according: oyster, rhodiola root.
2. the health products of a strong bone; It is characterized in that, form: oyster 60-200 gram, rhodiola root 40-100 gram, pumpkin seeds 20-80 gram, Chinese prickly ash 2-4 gram, capsicum 1-2 gram, isoflavones 1-2 gram, vitamin D 1-2 gram, Isin glue collagen 1-2 gram by following raw materials according.
3. health products according to claim 1 is characterized in that, are made up of following raw materials according: oyster 60 grams, rhodiola root 40 grams, pumpkin seeds 20 grams, Chinese prickly ash 2 grams, capsicum 1 gram, isoflavones 1 gram, vitamin D 1 gram, Isin glue collagen 1 gram.
4. the health products of a strong bone is characterized in that, are made up of following raw materials according: oyster 200 grams, rhodiola root 100 grams, pumpkin seeds 80 grams, Chinese prickly ash 4 grams, capsicum 2 grams, isoflavones 2 grams, vitamin D 2 grams, Isin glue collagen 2 grams.
5. preparation method like the health products of the said strong bone of claim 1-4 is characterized in that:
Each raw meal is broken into 80 order fine powders; With 75% alcohol extract 3 times, merging filtrate, concentrate, vacuum drying is pulverized.
6. preparation method like the health products of the said strong bone of claim 5 is characterized in that:
With xeraphium, microcrystalline cellulose, lactose, starch mixing is content, processes in the capsulae vacuus of packing into.
7. preparation method like the health products of the said strong bone of claim 5 is characterized in that:
With xeraphium 1-5 gram, microcrystalline cellulose 5-50 gram, lactose 1-10 gram, starch 2-20 gram mixing is content, processes in the capsulae vacuus of packing into.
8. preparation method like the health products of the said strong bone of claim 5 is characterized in that:
With xeraphium 1-5 gram, starch 1-10 gram, lactose 2-20 gram, microcrystalline cellulose 5-50 gram, dolomol 0.4-4 gram is processed 20 purpose particles with above raw material, is pressed into tablet.
CN2011103052273A 2011-10-10 2011-10-10 Health product used for supporting strong bones Active CN102406177B (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1395965A (en) * 2002-07-30 2003-02-12 青岛海洋大学 Nutritive refreshing medicine 'Haizhen'
CN1543857A (en) * 2003-11-13 2004-11-10 上海奥医高科技实业有限公司 Health food having functions of postponing senescence and increasing bone mineral density
CN1785427A (en) * 2005-11-21 2006-06-14 陈斌 Compound calcium preparation for astronaut
CN102090692A (en) * 2010-09-06 2011-06-15 山东好当家海洋发展股份有限公司 Oyster polypeptide anti-fatigue beverage and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1395965A (en) * 2002-07-30 2003-02-12 青岛海洋大学 Nutritive refreshing medicine 'Haizhen'
CN1543857A (en) * 2003-11-13 2004-11-10 上海奥医高科技实业有限公司 Health food having functions of postponing senescence and increasing bone mineral density
CN1785427A (en) * 2005-11-21 2006-06-14 陈斌 Compound calcium preparation for astronaut
CN102090692A (en) * 2010-09-06 2011-06-15 山东好当家海洋发展股份有限公司 Oyster polypeptide anti-fatigue beverage and preparation method thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
刘剑梅等: "红景天壮骨丸治疗骨质疏松症的实验研究", 《中国临床康复》 *
张华 等: "《骨质疏松症中西医治疗研究进展》", 《中医正骨》 *
白孟海等: "高原对去势大鼠骨密度、生物力学和骨组织学的影响及复方红景天对其保护作用", 《西北国防医学杂志》 *

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