CN102388064A - 用于筛选与使用拮抗孢子-表面交互作用的化合物的组合物与方法 - Google Patents

用于筛选与使用拮抗孢子-表面交互作用的化合物的组合物与方法 Download PDF

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Publication number
CN102388064A
CN102388064A CN2010800140986A CN201080014098A CN102388064A CN 102388064 A CN102388064 A CN 102388064A CN 2010800140986 A CN2010800140986 A CN 2010800140986A CN 201080014098 A CN201080014098 A CN 201080014098A CN 102388064 A CN102388064 A CN 102388064A
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spore
seq
compsn
protein
specific examples
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Chinese (zh)
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大卫·R·马希加
詹姆斯·艾德蒙·宾翰
莎拉·L·艾德蒙德斯
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Go-Jo Industries Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/40—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum bacterial
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN2010800140986A 2009-03-27 2010-03-26 用于筛选与使用拮抗孢子-表面交互作用的化合物的组合物与方法 Pending CN102388064A (zh)

Applications Claiming Priority (3)

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US16415409P 2009-03-27 2009-03-27
US61/164,154 2009-03-27
PCT/US2010/028902 WO2010126670A2 (en) 2009-03-27 2010-03-26 Compositions and methods for screening and using compounds antagonizing spore-surface interactions

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CN102388064A true CN102388064A (zh) 2012-03-21

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US (1) US20100291100A1 (enExample)
EP (1) EP2411410B1 (enExample)
JP (1) JP5911421B2 (enExample)
KR (1) KR20110140128A (enExample)
CN (1) CN102388064A (enExample)
AU (1) AU2010241947B2 (enExample)
BR (1) BRPI1014121A2 (enExample)
CA (1) CA2756760A1 (enExample)
DK (1) DK2411410T3 (enExample)
ES (1) ES2544435T3 (enExample)
PT (1) PT2411410E (enExample)
TW (1) TW201039841A (enExample)
WO (1) WO2010126670A2 (enExample)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109706101A (zh) * 2019-02-01 2019-05-03 东华大学 一种嗜冷芽孢八叠球菌及其应用
CN110879209A (zh) * 2019-12-09 2020-03-13 济南大学 一种γ-氨基丁酸的快速检测方法
CN113247946A (zh) * 2021-04-22 2021-08-13 哈尔滨工业大学 一种自主装纳米生物催化剂及其制备方法和在丁醇生产中的应用
CN113278578A (zh) * 2021-06-15 2021-08-20 广西大学 一种稻瘟病菌分生孢子的移植方法
CN113308431A (zh) * 2021-06-15 2021-08-27 广西大学 一种番茄灰霉病菌分生孢子的移植与分散方法
CN114807194A (zh) * 2020-08-31 2022-07-29 南京工业大学 一种提高梭菌中蛋白表达效率的方法

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WO2017176872A1 (en) * 2016-04-05 2017-10-12 Nch Corporation Nutrient rich germinant composition and spore incubation method
WO2018129249A1 (en) * 2017-01-05 2018-07-12 The University Of Chicago Inhibition of enteric infection through the modulation of microbiota
AU2018337974B2 (en) 2017-09-20 2024-06-27 Spogen Biotech Inc. Fusion proteins, recombinant bacteria, and exosporium fragments for plant health
WO2020247755A1 (en) * 2019-06-05 2020-12-10 Biovector, Inc. Aptamers against clostridium difficile
CA3180331A1 (en) * 2020-04-17 2021-10-21 Liv Process, Inc. Methods of reducing or preventing clostridioides difficile colonization
US11898146B2 (en) 2020-12-03 2024-02-13 Liv Process, Inc. Aptamers against Clostridium difficile, compositions comprising aptamers against Clostridium difficile and methods of using the same
EP4317438A1 (en) * 2021-03-30 2024-02-07 Asahi Kasei Kabushiki Kaisha Recombinant polypeptide having acyl-coa compound reducing activity

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109706101A (zh) * 2019-02-01 2019-05-03 东华大学 一种嗜冷芽孢八叠球菌及其应用
CN110879209A (zh) * 2019-12-09 2020-03-13 济南大学 一种γ-氨基丁酸的快速检测方法
CN114807194A (zh) * 2020-08-31 2022-07-29 南京工业大学 一种提高梭菌中蛋白表达效率的方法
CN114807194B (zh) * 2020-08-31 2023-05-12 南京工业大学 一种提高梭菌中蛋白表达效率的方法
CN113247946A (zh) * 2021-04-22 2021-08-13 哈尔滨工业大学 一种自主装纳米生物催化剂及其制备方法和在丁醇生产中的应用
CN113247946B (zh) * 2021-04-22 2022-07-05 哈尔滨工业大学 一种自组装纳米生物催化剂及其制备方法和在丁醇生产中的应用
CN113278578A (zh) * 2021-06-15 2021-08-20 广西大学 一种稻瘟病菌分生孢子的移植方法
CN113308431A (zh) * 2021-06-15 2021-08-27 广西大学 一种番茄灰霉病菌分生孢子的移植与分散方法

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BRPI1014121A2 (pt) 2016-11-08
TW201039841A (en) 2010-11-16
WO2010126670A3 (en) 2011-03-31
CA2756760A1 (en) 2010-11-04
PT2411410E (pt) 2015-10-09
AU2010241947A1 (en) 2011-11-17
US20100291100A1 (en) 2010-11-18
EP2411410B1 (en) 2015-07-08
KR20110140128A (ko) 2011-12-30
AU2010241947B2 (en) 2014-01-16
EP2411410A2 (en) 2012-02-01
JP2012522010A (ja) 2012-09-20
ES2544435T3 (es) 2015-08-31
WO2010126670A2 (en) 2010-11-04
DK2411410T3 (en) 2015-09-07
WO2010126670A9 (en) 2011-06-30
JP5911421B2 (ja) 2016-05-18

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