CN102385811A - Demonstration model for simulating pathological change of acute glomerulonephritis - Google Patents

Demonstration model for simulating pathological change of acute glomerulonephritis Download PDF

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Publication number
CN102385811A
CN102385811A CN2011103909722A CN201110390972A CN102385811A CN 102385811 A CN102385811 A CN 102385811A CN 2011103909722 A CN2011103909722 A CN 2011103909722A CN 201110390972 A CN201110390972 A CN 201110390972A CN 102385811 A CN102385811 A CN 102385811A
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model
blood vessel
glomerulus
arteriole
glomerular
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Chinese (zh)
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关真民
鹿勇
王慧
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Abstract

The invention relates to a demonstration model for simulating the pathological change of acute glomerulonephritis. The invention belongs to a medical teaching device, and particularly relates to a teaching aid for demonstrating the pathological change of acute glomerulonephritis. The teaching aid mainly comprises a heart model, an afferent glomerular arteriole model, a glomerular capillary u-shaped loop model, a mesangial region saccus model, an efferent glomerular arteriole model, a renal capsule model, a renal tubule model, a urine pool and a blood pool, thereby forming a model system for demonstrating the pathological clinical correlation of acute glomerulonephritis. The device is simple in structure and convenient to operate, and has high visuality and understandability in the teaching process. Besides, the device facilitates students to foster the observation and problem analysis capabilities.

Description

Simulation acute glomerulonephritis pathological change demonstrating model
Technical field
The invention belongs to medical teaching equipment, particularly demonstrate the teaching aid of acute glomerulonephritis pathological change.
Background technology
In theory of medicine teaching, medical knowledge is complicated often abstract, depends merely on to tell about to be difficult to let the student understand easily, mainly adopts multimedia teaching in recent years and has ignored the effect of demonstration mode teaching skill (like the model teaching aid demonstration) in teaching [2]Main through observing pathological section in experimental teaching, understand pathological characteristic under the glomerulonephritis mirror, getting in touch between pathological change of student's indigestion and the clinical manifestation.Someone provides urine to form demonstrator [1], simulated the physiology course that urine forms, but glomerulonephritis pathological characteristic and corresponding clinical manifestation fail to relate to like oliguresis, albuminuria, blood urine.
Summary of the invention
The purpose of this invention is to provide a kind of simulation acute glomerulonephritis pathological change demonstrating model.Simple in structure, easy to operate, the teaching visual and understandable, make abstract knowledge become vivid, and can demonstrate the incidence and development process of disease.
Realize that this practical new technique scheme is: mainly be made up of cardiac module, afferent glomerular arteriole model, glomerulus U type blood vessel loop model, mesangial region air bag model, efferent glomerular arteriole model, capsula glomeruli model, renal tubule model, urine pond and blood pool, cardiac module is communicated with the afferent glomerular arteriole model.Glomerulus blood vessel U model, an end links to each other with the afferent glomerular arteriole model, and the other end and efferent glomerular arteriole model join.Mesangial region air bag model is embedded in the middle of the glomerulus blood vessel U type loop, and glomerulus blood vessel U type loop model is placed in the capsula glomeruli mould impression, and glomerulus blood vessel U-shaped loop model pipe is provided with aperture, forms glomerular filtration membrane jointly with capsula glomeruli internal layer aperture.The renal tubule model is connected with the capsula glomeruli model, and the other end gets into the urine pond, and the efferent glomerular arteriole model gets into blood pool.
Description of drawings
Fig. 1 is a structural representation of the present invention
Among the figure,
The 1-cardiac module
2-afferent glomerular arteriole model
3-glomerulus blood vessel U type loop model
4-capsula glomeruli model internal layer aperture
5-mesangial region air bag model
6-glomerulus blood vessel U-shaped loop model aperture
7-efferent glomerular arteriole model
8-capsula glomeruli model
9-renal tubule model
The heavy absorption tube of 10-
11-urine pond
The 12-blood pool
13-afferent glomerular arteriole switch
14-renal tubule switch
15-red blood cell model
The 16-protein model.
Embodiment
A specific embodiment of the present invention that provides through Figure of description below further describes its structure.
Referring to accompanying drawing 1; The cardiac module 1 of this device is communicated with afferent glomerular arteriole model 2; Glomerulus blood vessel U type loop model 3 one ends link to each other with afferent glomerular arteriole model 2, and the other end and efferent glomerular arteriole model 7 join, and mesangial region air bag model 5 is embedded between the glomerulus blood vessel U type loop 3; Glomerulus blood vessel U type loop model 3 is placed in capsula glomeruli model 8 inner chambers, and glomerulus blood vessel U-shaped loop model 3 is provided with aperture 6.Renal tubule model 9 is connected with capsula glomeruli model 8, and the other end gets into urine pond 11.The efferent glomerular arteriole model 7 last blood pool 12 that get into.In this device; Cardiac module 1, afferent glomerular arteriole model 2, glomerulus blood vessel U type loop model 3; Efferent glomerular arteriole model 7; It is pink (simulate blood color) that blood pool 12 adopts transparent material and outward appearance, and capsula glomeruli model 8 renal tubule models 9 and urine pond 11 are transparent material (simulation urine color when water passes through).Mesangial region air bag model 5 balloon surface patterns are that (inflation increases simulation endothelial cell, proliferation of mesangial cells for endothelial cell, mesangial cell and matrix synoptic diagram.Capsula glomeruli model 8 is a double-decker, and profile is the flask shape, and internal layer has aperture 4, is mainly used in fixedly glomerulus blood vessel U type loop model 3 and filtration is arranged.
During use, add clear water at cardiac module 1, turn on afferent glomerular arteriole model switch 13, represent blood flow to flow into glomerulus U type blood vessel loop 3, liquid filters from glomerulus blood vessel U type loop aperture 6, leaches through capsula glomeruli model 8 internal layer apertures 4 then, and crude urine forms.Simultaneously, partially liq gets into blood pool 12 through efferent glomerular arteriole 7 in the glomerulus blood vessel U type loop 3.When acute diffuse glomerulonephritis takes place when; Endothelial cell, proliferation of mesangial cells; This moment mesangial region model air bag 5 inflation (simulation endothelial cell, mesangial cell hyperplasia hypertrophy) is made glomerulus blood vessel U type loop 3 pressurizeds and narrow, cause that clear water expands capsula glomeruli model internal layer apertures 4 from glomerulus blood vessel U type loop aperture 6 and leaches minimizings (the simulation glomerular filtration rate(GFR reduces) and formation oliguresis anuria even.Then red blood cell model 15, protein model 16 are added cardiac module 1, leach from glomerulus blood vessel U type loop aperture 6 and capsula glomeruli internal layer aperture 4 along with liquid is descending, simulation acute glomerulonephritis albuminuria, blood urine form.
See that from the above-mentioned teaching plan of the present invention this apparatus structure is simple, easy to operate, visual in image.Make acute glomerulonephritis pathological change, clinical pathology contact, to dynamically, look like specifically by taking out by static state.Can dynamically understand the incidence and development process of acute glomerulonephritis, improve the ability of observation of students problem analysis.
  
List of references
[1] Cui Weizhen. urine forms demonstrator. patent No. 99246944.9.2000.9.
[2] Wang Bin, old life is man. Pathology and Pathophysiology [M]. and the 6th edition. Beijing: People's Health Publisher .2009:232-233.

Claims (6)

1. simulate acute glomerulonephritis pathological change demonstrating model for one kind; It is characterized in that mainly forming by cardiac module, afferent glomerular arteriole model, glomerulus blood vessel U type loop model, mesangial region air bag model, efferent glomerular arteriole model, capsula glomeruli model, renal tubule model and urine pond; Cardiac module is communicated with the afferent glomerular arteriole model; Glomerulus blood vessel U type loop model one end is connected with the afferent glomerular arteriole model, and the other end is connected with the efferent glomerular arteriole model.
2. mesangial region air bag model is embedded in the middle of the glomerulus blood vessel U type loop, and glomerulus blood vessel U type loop model is placed in the capsula glomeruli mould impression, and glomerulus blood vessel U-shaped loop model pipe is provided with aperture, forms glomerular filtration membrane jointly with capsula glomeruli internal layer aperture.
3. the renal tubule model is connected with the capsula glomeruli model, the other end and entering urine pond.
4. the efferent glomerular arteriole model gets into blood pool at last.
5. by the described simulation acute glomerulonephritis of claim 1 pathological change demonstrating model; It is characterized in that cardiac module, afferent glomerular arteriole model, glomerulus blood vessel U type loop model; The afferent glomerular arteriole model; It is transparent material (simulation urine color when water passes through) for pink (simulate blood color) capsula glomeruli model, renal tubule model and urine pond that blood pool adopts transparent material and outward appearance, and mesangial region is an air bag, and the balloon surface pattern is endothelial cell, mesangial cell and matrix synoptic diagram.
6. red blood cells model (redness), protein model (yellow); Its proportion and water are together; Diameter is less than glomerulus blood vessel U type loop model aperture and capsula glomeruli internal layer aperture; Red blood cell, albumen when simulation acute glomerulonephritis glomerular filtration membrane permeability increases leach, and form albuminuria, blood urine presentation process.
CN2011103909722A 2011-12-01 2011-12-01 Demonstration model for simulating pathological change of acute glomerulonephritis Pending CN102385811A (en)

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102708746A (en) * 2012-06-25 2012-10-03 关真民 Malignant tumor lymphatic channel metastasis demonstration model
CN102723039A (en) * 2012-06-25 2012-10-10 关真民 Model for demonstrating tumor vascular dissemination
CN102750861A (en) * 2012-06-23 2012-10-24 关真民 Model for demonstrating implantation metastasis of gastric cancer
CN102750863A (en) * 2012-06-25 2012-10-24 关真民 Glomerulus and renal tubule disequilibrium demonstration model
CN103933615A (en) * 2014-04-08 2014-07-23 华南理工大学 Self-assembly porous polymer membrane for glomerular filtration membrane repairing, and preparation method and application thereof
CN104658392A (en) * 2014-07-17 2015-05-27 姚正林 Urine formation and excretion presenter
CN114209428A (en) * 2021-12-27 2022-03-22 湘南学院 Device for simulating acute kidney injury

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1404756A (en) * 1971-08-24 1975-09-03 Kerr D Model kidney nephron
CN2396465Y (en) * 1999-11-02 2000-09-13 崔维贞 Urine producing demonstrator
CN201600821U (en) * 2010-02-05 2010-10-06 北京医模科技有限公司 Section model of right kidney
CN201600820U (en) * 2010-02-05 2010-10-06 北京医模科技有限公司 Nephron model

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1404756A (en) * 1971-08-24 1975-09-03 Kerr D Model kidney nephron
CN2396465Y (en) * 1999-11-02 2000-09-13 崔维贞 Urine producing demonstrator
CN201600821U (en) * 2010-02-05 2010-10-06 北京医模科技有限公司 Section model of right kidney
CN201600820U (en) * 2010-02-05 2010-10-06 北京医模科技有限公司 Nephron model

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102750861A (en) * 2012-06-23 2012-10-24 关真民 Model for demonstrating implantation metastasis of gastric cancer
CN102708746A (en) * 2012-06-25 2012-10-03 关真民 Malignant tumor lymphatic channel metastasis demonstration model
CN102723039A (en) * 2012-06-25 2012-10-10 关真民 Model for demonstrating tumor vascular dissemination
CN102750863A (en) * 2012-06-25 2012-10-24 关真民 Glomerulus and renal tubule disequilibrium demonstration model
CN103933615A (en) * 2014-04-08 2014-07-23 华南理工大学 Self-assembly porous polymer membrane for glomerular filtration membrane repairing, and preparation method and application thereof
CN103933615B (en) * 2014-04-08 2015-10-28 华南理工大学 A kind of self-assembly porous polymeric film for glomerular filtration film healing and preparation method thereof and application
CN104658392A (en) * 2014-07-17 2015-05-27 姚正林 Urine formation and excretion presenter
CN104658392B (en) * 2014-07-17 2017-08-25 姚正林 The formation of urine and discharge demonstration device
CN114209428A (en) * 2021-12-27 2022-03-22 湘南学院 Device for simulating acute kidney injury
CN114209428B (en) * 2021-12-27 2024-01-30 湘南学院 Device for simulating acute kidney injury

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Application publication date: 20120321