CN102335250B - Health-care product used for treating initial infection of foot-and-mouth disease of sow - Google Patents
Health-care product used for treating initial infection of foot-and-mouth disease of sow Download PDFInfo
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- CN102335250B CN102335250B CN2011103231184A CN201110323118A CN102335250B CN 102335250 B CN102335250 B CN 102335250B CN 2011103231184 A CN2011103231184 A CN 2011103231184A CN 201110323118 A CN201110323118 A CN 201110323118A CN 102335250 B CN102335250 B CN 102335250B
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- sow
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- mouth disease
- health
- initial infection
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Abstract
The invention belongs to a preparation technology of animal health-care medicaments, and particularly relates to a health-care product used for treating initial infection of a foot-and-mouth disease of sow and containing pseudo-ginseng, borneol, pepperweed seed, astragalus mongholicus, poria and golden thread oral solution, and a preparation method thereof.
Description
Technical field
The invention belongs to the technology of preparing of animal health medicine, particularly a kind of Radix Notoginseng, Borneolum Syntheticum, Semen Lepidii (Semen Descurainiae), the Radix Astragali, Poria, the health product at Rhizoma Coptidis oral liquid treatment sow foot and mouth disease initial stage and preparation method thereof.
Background technology
Expansion along with the cultivation scale, increasing the weight of of environmental pollution, serious disease often appears in each plant, for example, Schweineseuche, foot and mouth disease is a kind of acute, hot, the height contagious disease that the Some Livestock such as pig, sow, sheep and other domestic, wild artiodactyl suffer from altogether, and susceptible animal reaches kind more than 70.Clinical symptoms is in oral mucosa, hoof and skin of breast generation vesicle rash.This disease route of transmission is many, speed is fast, and once outbreak of epidemic worldwide repeatedly caused huge politics, economic loss.Given this, OIE (OIE) classifies it first of category-A infectious disease as.At present, 2/3rds the popular FMD of OIE member state is arranged, threatening safety of livestock and Livestock Product Trade without the FMD countries and regions constantly; Cause huge economic loss to aquaculture.Effectively prevention and treatment Schweineseuche are one of this technical field scientific research personnel new problems of being badly in need of developing.
Technical scheme
The present invention relates to a kind of health product for the treatment of sow foot and mouth disease treating initial infection, is the oral liquid of being made by Radix Notoginseng, Borneolum Syntheticum, Semen Lepidii (Semen Descurainiae), the Radix Astragali, Poria, Rhizoma Coptidis, Semen Vaccariae.
The present invention relates to a kind of health product for the treatment of sow foot and mouth disease treating initial infection, is to be made by the raw material of following weight portion:
The oral liquid that Radix Notoginseng 3-8, Borneolum Syntheticum 1-2, Semen Lepidii (Semen Descurainiae) 5-7, Radix Astragali 4-10, Poria 20-30, Rhizoma Coptidis 10-20, Semen Vaccariae 20-40 make.
The present invention relates to a kind of health product for the treatment of sow foot and mouth disease treating initial infection, is to be made by the raw material of following weight portion:
Radix Notoginseng 3-8, Semen Lepidii (Semen Descurainiae) 5-7, Radix Astragali 4-10, Poria 20-30, Rhizoma Coptidis 10-20, Semen Vaccariae 20-40; Boil with the 400-800 decocting, with the ethanol precipitation, filter, obtain filtrate for later use; Borneolum Syntheticum 1-2 dissolves with appropriate amount of ethanol; Mix with filtrate, obtain oral liquid.
Protection scope of the present invention includes, without being limited to the described scope of Ben Wenben.
The specific embodiment:
Embodiment 1
A kind of health product for the treatment of sow foot and mouth disease treating initial infection are to be made by the raw material of following weight portion:
Radix Notoginseng 3g, Semen Lepidii (Semen Descurainiae) 5g, Radix Astragali 4g, Poria 20g, Rhizoma Coptidis 10g, Semen Vaccariae 20g boil with the 400g decocting, with 25g ethanol precipitation, filter, and obtain filtrate for later use; Borneolum Syntheticum 1g dissolves with appropriate amount of ethanol, mixes with filtrate, obtains oral liquid.
Embodiment 2
A kind of health product for the treatment of sow foot and mouth disease treating initial infection are to be made by the raw material of following weight portion:
Radix Notoginseng 8 g, Semen Lepidii (Semen Descurainiae) 7 g, the Radix Astragali 10 g, Poria 30 g, Rhizoma Coptidis 20 g, Semen Vaccariae 40 g boil with 800 g decoctings, with 30 g ethanol precipitation, filter, and obtain filtrate for later use; Borneolum Syntheticum 2 g dissolve with appropriate amount of ethanol, mix with filtrate, obtain oral liquid.
Embodiment 3
A kind of health product for the treatment of sow foot and mouth disease treating initial infection are to be made by following raw material:
Radix Notoginseng 5g, Semen Lepidii (Semen Descurainiae) 6g, Radix Astragali 8g, Poria 25g, Rhizoma Coptidis 15g, Semen Vaccariae 30g boil with the 500g decocting, with 20g ethanol precipitation, filter, and obtain filtrate for later use; Borneolum Syntheticum 1.5g dissolves with appropriate amount of ethanol, mixes with filtrate, obtains oral liquid.
Embodiment 4 the present invention are to the effect of sow foot and mouth disease treating initial infection:
Certain pig farm, in June, 2008, the foot and mouth disease epidemic diseases has occured in 20 sows, symptom is: fervescence, difficulty in walking, oral cavity, tongue, throat, still do not have blister, also occur rotten to the corn, scorching without gastrointestinal hemorrhage, hoof blister and festering.
The mixing embodiment of the invention 2 products in drinking-water, 40mg crude drug/kg body weight 1 time on the 2nd, is used in conjunction 5 days:
6 foot and mouth disease symptom disappeared at 4-5 days,
2 foot and mouth disease symptom disappeared at the 10th day,
1 foot and mouth disease symptom disappeared at the 13rd day,
1 invalid, death.
Embodiment 5 the present invention are to the immanoprotection action of sow foot and mouth disease
On June 15th, 2009, because foot and mouth disease occurs in the surrounding area, 10 sows of certain pig farm are just being prepared breeding, thus in drinking-water the mixing embodiment of the invention 2 products, 40mg crude drug/kg body weight 1 time on the 2nd, is used in conjunction 5 days.On July 2nd, 2009, Schweineseuche occurs in this sheep raising factory.
Take 20 sows of the embodiment of the invention 2 products, only have 1 the Schweineseuche symptom to occur.And 10 sows that do not take the embodiment of the invention 2 products have 4 and sheep foot and mouth disease symptom occurred.
Embodiment 6 the present invention are to the immanoprotection action of sow foot and mouth disease
Laboratory animal: the 6-18 month health sow in same kind, source, O type antibodies against foot-and-mouth disease virus is all negative in the serum.
The experiment grouping: sow health product group: the mixing embodiment of the invention 2 products in drinking-water, 40mg crude drug/kg body weight 1 time on the 2nd, is used in conjunction 5 days.Sow FMD inactivated vaccine positive controls: Schweineseuche O-shaped inactivated vaccine, 400 μ g/ml, 2 milliliters/only/time, intragluteal injection.PBS negative control group: PBS, 1 ml/only/time, intragluteal injection.
In after administration the 20th day of each group, at the strong and weak strain of sow ear subcutaneous injection pig O type foot and mouth disease virus, 10000ID40/0.1ml.The 5th day judgement incidence behind injecting virus.
Except the lingual surface of injecting virus, blister appears in gingiva, oral cavity, four hoof, any position of nipple, can be judged as morbidity.Blister appears in the sow to two of a negative control group hoof, can judge counteracting toxic substances experiment establishment.
The results are shown in Table.Experimental result shows that the embodiment of the invention 2 products have the effect of prevention sow O type mouth disease virus infection.
| The experiment grouping | Sow (only) | Sow (only) does not fall ill | Morbidity sow (only) |
| Sow health product group | 10 | 9 | 1 |
| Sow foot and mouth disease bivalence inactivated vaccine positive controls | 10 | 6 | 4 |
| The PBS negative control group | 10 | 0 | 10 |
Claims (1)
1. health product for the treatment of sow foot and mouth disease treating initial infection are to be made by the raw material of following weight portion:
Radix Notoginseng 3-8, Semen Lepidii (Semen Descurainiae) 5-7, Radix Astragali 4-10, Poria 20-30, Rhizoma Coptidis 10-20, Semen Vaccariae 20-40 boil with the 400-800 decocting, with the ethanol precipitation, filter, and obtain filtrate for later use; Borneolum Syntheticum 1-2 dissolves with appropriate amount of ethanol; Mix with filtrate, obtain oral liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011103231184A CN102335250B (en) | 2011-10-22 | 2011-10-22 | Health-care product used for treating initial infection of foot-and-mouth disease of sow |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011103231184A CN102335250B (en) | 2011-10-22 | 2011-10-22 | Health-care product used for treating initial infection of foot-and-mouth disease of sow |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102335250A CN102335250A (en) | 2012-02-01 |
| CN102335250B true CN102335250B (en) | 2013-02-20 |
Family
ID=45511351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011103231184A Expired - Fee Related CN102335250B (en) | 2011-10-22 | 2011-10-22 | Health-care product used for treating initial infection of foot-and-mouth disease of sow |
Country Status (1)
| Country | Link |
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| CN (1) | CN102335250B (en) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101297889B (en) * | 2007-08-31 | 2010-09-01 | 天津生机集团有限公司 | Chinese medicine preparation for treating foot-and-mouth disease and preparation method thereof |
| CN101391040A (en) * | 2008-10-23 | 2009-03-25 | 蒋勇 | External medicine for treating foot and mouth disease |
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2011
- 2011-10-22 CN CN2011103231184A patent/CN102335250B/en not_active Expired - Fee Related
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| Publication number | Publication date |
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| CN102335250A (en) | 2012-02-01 |
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