CN1023294C - Surgical application base for curing wound and preparing process thereof - Google Patents
Surgical application base for curing wound and preparing process thereof Download PDFInfo
- Publication number
- CN1023294C CN1023294C CN 90100236 CN90100236A CN1023294C CN 1023294 C CN1023294 C CN 1023294C CN 90100236 CN90100236 CN 90100236 CN 90100236 A CN90100236 A CN 90100236A CN 1023294 C CN1023294 C CN 1023294C
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- CN
- China
- Prior art keywords
- sodium alginate
- supporter
- dressing
- surgical
- solution
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Abstract
The present invention discloses a surgical sodium alginate dressing for treating a wound and a preparation technique thereof. The present invention is characterized in that a supporter is a flexible, porous and permeable synthesized polymer material or a natural polymer material. During the preparation process, prepared sodium alginate medicine liquid is adsorbed by the preprocessed supporter, so that the content of the supporter is from 0.8 to 1.4 mg/cm<2>; next, the sodium alginate medicine liquid dried and cooled to obtain the surgical sodium alginate dressing. The surgical sodium alginate dressing has the advantages of wide material sources, good flexibility, good porosity, good air permeability, simple preparation process and convenient industrial production. The surgical sodium alginate dressing which is applied to surgical clinic has obvious curative effects on hemostasis, analgesia, inflammation relieving, detumescence and wound healing.
Description
The present invention relates to a kind of dressing dosage form, the particularly a kind of wound dressing dosage form that use, that on supporter, be mixed with medicine and the preparation technology of this dosage form.
After the potential value that twentieth century four, the fifties, alginic acid and its salt have antiinflammatory, analgesic effectiveness is found, just begins to be employed as surgery and apply section.Through domestic and international patent documentation of preliminary search and data, at present, the dressing dosage form of alginic acid and its salt has two classes substantially, and a class adopts supporter, one class without supporter by Sodium Alginate form through calcification gel layer or through reel off raw silk from cocoons, spray webbing forms fibrous cover layer, straight forming.
Finding the clear and 54-92618 patent of invention of Japan, is exactly the example of last class.This invention is coated on by " wet-cloth agent " that the process of Sodium Alginate calcification is made and makes it gelation on the base cloth of supporter flannelette, gauze, non-woven fabrics or paper etc. and make " wet-cloth agent " dressing.This dressing paste is distributed on the skin, though can receive antiinflammatory, analgesic effect, because " wet-cloth agent " on the supporter of this dressing forms gel, so make dressing soft inadequately, porous, breathability are also not enough, and need expend a large amount of cottons.
Purpose of the present invention is intended to propose one at above-mentioned shortcoming and adopts flexibility, porous, macromolecular material good air permeability, wide material sources as supporter, absorption need not be passed through the solution of sodium alginate of calcification and make the simple and convenient of new dressing dosage form and this dosage form dressing of preparation, with low cost, be convenient to the scheme of the process of suitability for industrialized production.
Dosage form of the present invention is achieved in that
That Sodium Alginate surgical dressing dosage form adopts is soft, porous, gas-pervious synthesized polymer material or natural macromolecular material be as supporter, the solution of sodium alginate that absorption prepares, drying, cooling and molding.
The synthesized polymer material of the supporter that dosage form of the present invention adopts such as foam rubber, foam plastics, its thickness is 1～5mm, natural macromolecular material such as viscose rayon, its thickness is 0.1～0.5mm.
The preparation technology of dosage form of the present invention is achieved in that
(1) above-mentioned supporter purified, wash, dry, sterilize, dry, activate, the pretreatment of dehydration, distilled water wash, drying and other steps;
(2) at normal temperatures and pressures, be immersed in through pretreated supporter with above-mentioned that (prescription of medicinal liquid is: Sodium Alginate 5-60% in the solution of sodium alginate for preparing, each is an amount of for surfactant, antiseptic, softening agent, add water to 100% at last), make this supporter adsorb this medicinal liquid, controlling content is at 0.8-1.4mg/cm
2;
(3) finish supporter drying, the cooling forming of absorption.
Dosage form uniqueness of the present invention, not only the supporter substrate softness of Xuan Zeing, porous, ventilative, and owing to the absorption Sodium Alginate does not have the formation gel without calcification, make the dressing of this dosage form have more flexibility, can alleviate the subject discomfort sense during use, both be applicable to clinical, can be used as circulation of commodities again, can save a large amount of cottons, and preparation technology is simple, cost is low, is convenient to suitability for industrialized production.
Be several embodiment below:
Embodiment 1
Get the thick bubble of 1mm and wash one's hair rubber-purification-washing-drying-sterilization-drying-activation-dehydration-distilled water wash-drying-absorption solution of sodium alginate, making content is 0.8mg/cm
2-drying-cooling forming.
Embodiment 2
Getting the thick foam plastics-purification of 5mm-washing-drying-sterilization-drying-activation-dehydration-distilled water wash-drying-absorption solution of sodium alginate, to make content be 1.4mg/cm
2-drying-cooling forming.
Embodiment 3
Get the thick viscose rayon-purification of 0.1mm-washing-drying-sterilization-drying-activation-dehydration-distilled water wash-drying-absorption solution of sodium alginate, making content is 1.0mg/cm
2-drying-cooling forming.
Embodiment 4
Get the thick viscose rayon-purification of 0.5mm-washing-drying-sterilization-washing-drying-activation-dehydration-distilled water wash-drying-absorption solution of sodium alginate, making content is 1.4mg/cm
2-drying-cooling forming.
With this not only simple but also be convenient to this Sodium Alginate dressing flexibility, porous, the good air permeability that the process of suitability for industrialized production is made, the dosage form uniqueness, be applied to treat on the surgery of wound, hemostasis, analgesia, antiinflammatory, detumescence, healing of wound is evident in efficacy, low cost product has vast market prospect.
The dressing of dosage form of the present invention will come out with the commodity of " a card spirit " by name.
Claims (7)
1, a kind of alginate surgical dressing for the treatment of wound, it is characterized in that this dressing has adopted supporter, and on supporter, having adsorbed the solution of sodium alginate of solubility, the supporter that is adopted is a kind of soft, porous, gas-pervious foam rubber or viscose rayon.
2, dressing as claimed in claim 1 is characterized in that said solution of sodium alginate adsorbance is 0.8-1.4mg/cm
2
3, dressing according to claim 1, it is characterized in that said solution of sodium alginate prescription is: Sodium Alginate: 5-60%, each is an amount of for surfactant, antiseptic, softening agent, adds water to 100% at last.
4, dressing according to claim 1, the thickness that it is characterized in that the foam rubber supporter is 1-5mm.
5, dressing according to claim 1, the thickness that it is characterized in that the viscose rayon supporter is 0.1-0.5mm.
6, a kind of preparation technology who treats the Sodium Alginate surgical dressing of wound, it is characterized in that at normal temperatures and pressures, foam rubber or viscose rayon are immersed in the solution of sodium alginate for preparing, the prescription of said solution of sodium alginate is: Sodium Alginate: 5-60%, each is an amount of for surfactant, antiseptic, softening agent, add water to 100% at last, make supporter adsorb this medicinal liquid, controlling content is at 0.8-1.4mg/cm
2, dry then, cooling forming.
7, preparation technology as claimed in claim 6 is characterized in that, said supporter is carried out pretreatment, comprising: purification, washing, sterilization, activation, dehydration, washing, drying and other steps.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 90100236 CN1023294C (en) | 1990-01-09 | 1990-01-09 | Surgical application base for curing wound and preparing process thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 90100236 CN1023294C (en) | 1990-01-09 | 1990-01-09 | Surgical application base for curing wound and preparing process thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1043626A CN1043626A (en) | 1990-07-11 |
| CN1023294C true CN1023294C (en) | 1993-12-29 |
Family
ID=4876546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 90100236 Expired - Fee Related CN1023294C (en) | 1990-01-09 | 1990-01-09 | Surgical application base for curing wound and preparing process thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1023294C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100374167C (en) * | 2003-10-13 | 2008-03-12 | 汕头市美佳源实业有限公司 | Method for preparing aloe dressing preparation by letting prop absorbing aloe liquid and its application |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9618565D0 (en) * | 1996-09-05 | 1996-10-16 | Bristol Myers Co | Wound dressing |
-
1990
- 1990-01-09 CN CN 90100236 patent/CN1023294C/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100374167C (en) * | 2003-10-13 | 2008-03-12 | 汕头市美佳源实业有限公司 | Method for preparing aloe dressing preparation by letting prop absorbing aloe liquid and its application |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1043626A (en) | 1990-07-11 |
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| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |