CN102318827A - Nutrient composition and health care product for promoting development of nervous system - Google Patents

Nutrient composition and health care product for promoting development of nervous system Download PDF

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CN102318827A
CN102318827A CN 201110200029 CN201110200029A CN102318827A CN 102318827 A CN102318827 A CN 102318827A CN 201110200029 CN201110200029 CN 201110200029 CN 201110200029 A CN201110200029 A CN 201110200029A CN 102318827 A CN102318827 A CN 102318827A
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dha
ala
nutrient
nervous system
nutrient composition
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CN102318827B (en
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孙俊
邵胜荣
胡钢亮
吕庆中
张爱玲
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Hangzhou Qiandaohu Canobank Health Product Co ltd
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ZHEJIANG CONBA HEALTH PRODUCTS CO Ltd
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Abstract

The invention relates to a nutrient composition and a health care product for promoting the development of a nervous system. The nutrient composition comprises nutrients consisting of DHA (Docosahexaenoic Acid) and ALA (Alpha Lipoic Acid), wherein the mass ratio of DHA to ALA is 1:20 to 20:1. The composition of unsaturated fatty acid DHA and ALA has the functions of promoting the development of intelligence and vision; and the functional effects of the composition are prior to the effects of only supplying the same amount of DHA or ALA. DHA existing in the composition can satisfy the DHA direct requirements of an organism, and simultaneously, ALA is also continuously converted into DHA, thus the DHA subsequent requirements of the organism during a long time can be satisfied; and furthermore, ALA can also be used for activating the enzyme participating in the conversion from ALA to DHA in the organism, therefore, the conversion and synthesis capability of DHA from other foods can be increased when an individual stops ingesting a DHA/ALA product and the promotion action can be kept for a long time.

Description

A kind of nutrient composition and health products that promote nervous system development
Technical field
The present invention relates to a kind of nutrient composition, more particularly, relate to a kind of nutrient composition and health products that promote nervous system development.
Background technology
Unrighted acid is a kind of aliphatic acid of needed by human; Comprise monounsaturated fatty acids such as oleic acid and polyunsaturated fatty acid such as LA (linoleic acid), LNA (leukotrienes), AA (arachidonic acid), DHA (DHA) etc.; Polyunsaturated fatty acid is because of its design feature and different at human body metabolism's mutual transform mode, and it is serial like LA, AA etc. like DHA, ALA (alpha-linolenic acid) etc. and ω-6 to be divided into ω-3 series again.
DHA is an indispensable important component part in brain cell and the nerve fiber, to keeping cellular morphology and physiological function is extremely important.The content of DHA in biomembrane increases, and is all influential to the activity of the permeability of the flowability of film, material, acceptor, thereby influence the function of film, helps strengthening the transmission of nerve information, enhancing brain and neural activity.Clinical research shows that DHA helps improving ability of learning and memory, helps nervous system development, improves amphiblestroid function (Jiangsu Science & Engineering Univ.'s journal, 1996,17 (10): 10-15).DHA accounts for 10% of people's cephalopin, and content is abundant in people's retina, and mainly the form with phosphatide exists, and in fetal brain formation, cardiovascular system generation and optic nerve systematic function are grown, plays important using most.Discovering in recent years, DHA has the important physical effect to growing of infant, can promote infant's intelligence and eyesight to grow; And infant DHA content state depends on the intake of parent at conceived and lactation of DHA; Therefore add DHA to pregnant and lying-in women's DHA absorption situation and in infant's diatery supplement and more and more come into one's own, world many countries comprises China; All ratify DHA as nutrition fortifier, and formulated corresponding interpolation standard.
DHA (DHA) belongs to ω-3 type polyunsaturated fatty acid, is that human body self is difficult to synthesize, and needs the essential fatty acid that provided by food, can directly replenish or is transformed by the oleic acid of ingesting, LA or ALA through the DHA that ingests.But in animal body, oleic acid of ingesting or LA mainly change into AA, and synthetic DHA is few and slow, and the DHA in the human body mainly is transformed by ALA.But if the highly purified DHA of simple absorption then influences the competitive equilibrium metabolism in vivo of other polyunsaturated fatty acids easily; As only take in high-purity DHA and will reduce in the human body oleic acid to the conversion of AA; Break the balanced in nutrition of brain; Long-term excessively take in high-purity DHA and ignore the absorption balance of DHA and other polyunsaturated fatty acids; Be unfavorable for DHA absorption in vivo and utilization on the contrary, especially brain tissue and nervous system are in the gold infant in period, more likely have the risk that influences its intelligence and cognitive power growth.In addition, replenishing excessive DHA also has bad reaction, as increases the weight of hemorrhagic tendency and cause body lipid peroxidating etc.
LNA (leukotrienes) is that a kind of polyunsaturated fatty acid that contains three two keys is the serial polyenoic fatty acid of ω-3, because of the position of double bond difference is divided into alpha-linolenic acid and gamma-Linolenic acid.ALA (alpha-linolenic acid) is that human body self can not synthesize, the essential fatty acid that must be provided by food.ALA is the basic substance that constitutes cell membrane and biology enzyme, and health is played a decisive role, if lack sufficient ALA, neurilemmal formation can change, thereby influences intelligence and visual acuity.After ALA gets into human body, under the effect of carbochain growth and desaturase, can generate a series of metabolites, the most important thing is that wherein to the material that human body (especially brain) is highly profitable be DHA, EPA (eicosapentaenoic acid) through liver metabolism.Leukotrienes and metabolite thereof are except the effect with brain tonic and intelligence development; They also optionally infiltrate in vitals such as retina and the tissue; Participate in constituting monoethanolamine phosphatide and lipid sphyngomyelin, to vision, fat metabolism, embryo growth and development and immunologic function performance significant role.Have research data to show that the pregnant woman lacks leukotrienes, DHA content reduces 50% in the amphiblestroid phosphatide of newborn baby, and cerebral gray matter reduces 25%, influences the growth of intelligence and eyesight.
After ALA got into body, through the synthetic DHA of beta oxidation, but ALA was converted into the metabolic process that relates to 3 kinds of enzymes in the process of DHA under the effect of peroxisome, so transformation efficiency is lower.To the conversion ratio of DHA and EPA different research reports is arranged for ALA; Wherein have and report that the interior ALA that takes in of human body has 2%～5% to be converted into DHA; Also have other to report that ALA is 9% to the conversion ratio of DHA, this shows that human body is restricted by the synthetic DHA of alpha-linolenic acid.Be badly in need of replenishing under the situation of DHA at body,, rely on the DHA that transforms by ALA like the simple ALA that replenishes; Its amount can not effectively satisfy psychological need; The ALA that takes in can not change into DHA effectively, comparatively apace, and the simple linolenic bioavailability of taking in is lower, causes the waste of this nutrient; Simultaneously excessive ALA is present in the body also the unsaturated double-bond generation peroxidization that can contain because of its structure, causes that the body lipid peroxidating causes many health hazard problems.
By on can know; Owing to there is the relation of metabolic conversion between DHA, the ALA; And there are competition metabolism relation in DHA and ALA and other unrighted acids, and therefore, replenishing DHA merely can influence absorption and the utilization of other unrighted acids at body; Can not satisfy the capacity demand of body because of the DHA conversion ratio is not high and replenish ALA merely, can bring many health hazard problems because of excessive absorption reduces ALA bioavilability in vivo simultaneously DHA.When actual production DHA goods, be difficult to confirm DHA, the absolute magnitude of two kinds of nutrients of ALA and suitable content ratio, thereby be difficult to confirm contain the addition of the raw material of these two kinds of nutrients, influence the result of use of DHA goods.
Summary of the invention
The objective of the invention is to solve problem set forth above; Provide a kind of ratio collocation science balanced; Can effectively promote newborn body intelligence and eyesight to grow, improve immunity, a kind of nutrient composition and the health products that promote nervous system development that have high stability simultaneously.
Technical scheme of the present invention is such:
A kind of nutrient composition that promotes nervous system development comprises nutrient, and described nutrient comprises DHA (DHA) and ALA (alpha-linolenic acid), and the mass ratio of described DHA and ALA is 1: 20～20: 1.
As preferably, the mass ratio of described DHA and ALA is 1: 10～15: 1.
As preferably, the mass ratio of described DHA and ALA is 1: 5～8: 1.
As preferably, the mass ratio of described DHA and ALA is 1: 2～8: 1.
As preferably, described nutrient also comprises one or more in AA (arachidonic acid), taurine, folic acid, lecithin, reinforcement choline, the zinc gluconate.
As preferably, described nutrient composition also comprises edible antioxidant.
As preferably, described edible antioxidant can be one or more in vitamin E, vitamin C, Tea Polyphenols, beta carotene, lycopene, BHA, BHT, TBHQ, n-propyl gallate, the different sodium sorbate.
As preferably, nutrient composition is made up of 97%～99.98% nutrient and 0.02～3% edible antioxidant by weight percentage.
A kind of nutrient and healthcare products that promote nervous system development contain the nutrient composition that promotes nervous system development.
As preferably, finished dosage forms can be soft capsule or microcapsules or capsule or tablet or finish or granule, and wherein nutrient composition accounts for 0.1%～100% of finished product gross mass.
As preferably, wherein nutrient composition accounts for 5%～95% of finished product gross mass.
As preferably, wherein nutrient composition accounts for 10%～85% of finished product gross mass.
As preferably, wherein nutrient composition accounts for 20%～65% of finished product gross mass.
Beneficial effect of the present invention is following:
The composition of unrighted acid DHA and ALA has the function that promotes that intelligence and eyesight are grown, and the functional effect of composition is superior to simple effect of replenishing with amount DHA or ALA.Ready-made DHA can satisfy the direct demand of body to DHA in the composition; ALA is also continuing to change into DHA simultaneously; Can satisfy in the long period body to the subsequent need of DHA, ALA also can intensify in the body and transforms the activity of the enzyme of being participated in by ALA to DHA in addition, thereby makes individual behind the DHA/ALA goods that stop to ingest; Improve body the DHA in other food sources is transformed synthesis capability, and this facilitation can be kept the long time.
The specific embodiment
Be further elaborated in the face of embodiments of the invention down:
A kind of nutrient composition that promotes nervous system development comprises nutrient, and described nutrient comprises DHA (DHA) and ALA (alpha-linolenic acid), and the mass ratio of described DHA and ALA is 1: 20～20: 1.
The mass ratio of described DHA and ALA is 1: 10～15: 1.
For reaching further effect, the mass ratio of described DHA and ALA also can be 1: 8～10: 1.
For reaching further effect, the mass ratio of described DHA and ALA also can be 1: 5～8: 1.
For reaching further effect, the mass ratio of described DHA and ALA also can be 1: 2～8: 1.
Described nutrient also comprises one or more in AA (arachidonic acid), taurine, folic acid, lecithin, reinforcement choline, the zinc gluconate.
Described nutrient composition also comprises edible antioxidant.
Described edible antioxidant can be vitamin E, vitamin C, Tea Polyphenols, beta carotene, lycopene, BHA (butylated hydroxy anisole), BHT (2; The 6-di-tert-butyl-4-methy phenol, antioxidant 264), among the TBHQ (ditert-butylhydro quinone), n-propyl gallate, different sodium sorbate one or more another name:.
Nutrient composition is made up of 97%～99.98% nutrient and 0.02～3% edible antioxidant by weight percentage.
A kind of nutrient and healthcare products that promote nervous system development contain the nutrient composition that promotes intellectual development.
Finished dosage forms can be soft capsule or microcapsules or capsule or tablet or finish or granule, and wherein nutrient composition accounts for 0.1%～100% of finished product gross mass.
In order to reach further effect, wherein nutrient composition also can account for 5%～95% of finished product gross mass.
In order to reach further effect, wherein nutrient composition also can account for 10%～85% of finished product gross mass.
In order to reach further effect, wherein nutrient composition also can account for 20%～65% of finished product gross mass.
Wherein contained DHA source can be fish oil, algae oil, marine microorganism etc. in the composition, and contained ALA source can be daily edible vegetable oil such as rapeseed oil, sunflower oil, corn oil and soya-bean oil etc. or can derive from special lard oil such as linseed, purple perilla seed, ' Heijialun ' seed, tea-seed oil etc. perhaps can derive from nut fruits such as peanut, walnut, fibert etc. in the composition.Also contain the nutrient that other can promote that cranial nerve, optic nerve are grown in the said composition, other nutrients can be AA, taurine, folic acid, lecithin, reinforcement choline, zinc gluconate etc.The combined amount of each nutrient source material is to decide according to its contained nutrient content in the nutrient composition, is according to the content of distinguishing contained DHA, ALA and AA in algal oil, linseed oil, the peanut oil separately and fixed like algal oil, linseed oil, peanut oil combined amount.
Embodiment one [DHA: ALA=10: 1]
Under the normal temperature; Take by weighing weight percent and be 50% algae oil (DHA content 40%), 4% linseed oil (ALA content 50%), 45.68% peanut oil (containing AA), 0.3% vitamin E; 0.02% TBHQ pours in cleaning, the light resistant container, the covered container lid, and stirring at normal temperature is emitted after full and uniform; Screen pack makes composition.
With the gelatin is sizing material, and glycerine is plasticizer.Measure water by recipe quantity, mix, add gelatin dipping a period of time, gelatin is expanded with glycerine; Put then and be heated to uniform temperature in the glue pot, mix, being evacuated to does not have bubble; With sieve aperture internal diameter 100 order stainless steel sift net filtrations, filtrating (being glue) is put in the glue-storing barrel and is left standstill, heat preservation for standby use.
Above-mentioned composition that makes (as soft capsule content) and glue are added respectively in the encapsulating machine, and every loading of control feed liquid is pressed into soft capsule.The soft capsule that makes is finalized the design under the condition of certain temperature and humidity, moves into drying machine afterwards and carries out drying, promptly makes content nutrient composition mass percent and accounts for 70% soft capsule finished product.
Embodiment two [DHA: ALA=1: 20]
In the present embodiment; Take by weighing 5% algae oil (DHA content 40%), 80% linseed oil (ALA content 50%), 14.68% peanut oil, 0.3% vitamin E; 0.02% TBHQ carries out mixing, filtration according to preparation of compositions method among the embodiment one, makes the nutrient composition percentage by weight and be 100% finish finished product.
Embodiment three [DHA: ALA=20: 1]
In the present embodiment; Take by weighing 90% algae oil (DHA content 40%), 3.6% linseed oil (ALA content 50%), 6.1% peanut oil, 0.3% vitamin E; Carry out mixing, filtration according to preparation of compositions method among the embodiment one, make the nutrient composition percentage by weight and be 100% finish finished product.
Embodiment four [DHA: ALA=15: 1]
In the present embodiment, take by weighing 70% algae oil (DHA content 40%), 3.7% linseed oil (ALA content 50%), 26% peanut oil, 0.3% vitamin E, carry out mixing, filtration, make composition according to preparation of compositions method among the embodiment one.The above-mentioned composition that makes and glue are made content nutrient composition mass percent according to the soft capsule preparation method of embodiment one account for 85% soft capsule finished product.
Embodiment five [DHA: ALA=8: 1]
In the present embodiment; Take by weighing percentage by weight and be 68% algae oil (DHA content 35%), 5.95% linseed oil (ALA content 50%), 21.94% peanut oil, 3% lecithin, 1% taurine, 0.05% vitamin C, 0.05% vitamin C, 0.01% beta carotene carries out mixing, filtration according to the preparation method of composition among the embodiment one, makes composition.
Under the normal temperature, taking by weighing composition that embodiment five makes, to join percentage by weight be in 5% peanut oil, fully mixes, and promptly makes the nutrient composition percentage by weight and be 95% finish finished product.
Embodiment six [DHA: ALA=5: 1]
In the present embodiment; Take by weighing percentage by weight and be 80% fish oil (DHA content 12.5%), 3.33% Purple Perilla Seed Oil (ALA content 60%), 15% peanut oil, 1.47% lecithin, 0.1% vitamin E, 0.05% Tea Polyphenols, 0.05% lycopene and carry out preparation of compositions; Method makes composition with the preparation method of composition among the embodiment one.
Taking by weighing the percentage by weight that embodiment six makes is that 20% composition is as core; The maltodextrin and the conduct of cow's milk protein isolate that take by weighing constant weight are the wall material; The soybean lecithin that takes by weighing constant weight is an emulsifying agent; Maltodextrin and cow's milk protein isolate are dissolved in the warm water, keep mixed solution, stir certain hour in uniform temperature.Add composition and soybean lecithin that embodiment three makes again; Under the keeping warm mode; Keep certain rotating speed and stir, form stable emulsion, then with emulsion homogeneous 3 times under certain pressure; Emulsion behind the homogeneous carries out spray-drying, promptly makes the nutrient composition mass percent and be 20% microcapsules finished product.
Embodiment seven [DHA: ALA=1: 1.7]
In the present embodiment; Taking by weighing percentage by weight is 25% algae oil (DHA content 40%), 33.4% linseed oil (ALA content 50%), 34.98% peanut oil, 5% zinc gluconate, 0.5% taurine, 1.0% lecithin, 0.1% vitamin E; 0.02%TBHQ; Carry out mixing, filtration according to embodiment one preparation of compositions method, make composition.The above-mentioned composition that makes and glue are made content nutrient composition mass percent according to the soft capsule preparation method of embodiment one account for 75% soft capsule finished product.
Embodiment eight [DHA: ALA=1: 8]
In the present embodiment; Take by weighing percentage by weight and be 10% algae oil-bound distemper (DHA content 10%), 13.4% Purple Perilla Seed Oil powder (ALA content 60%), 73.33% peanut oil, 2.5% taurine, 0.05% folic acid, 0.5% zinc gluconate, 0.1% vitamin E, 0.1% vitamin C, 0.02%TBHQ and carry out mixing, filtration, make composition by embodiment one preparation method of composition.
With embodiment eight gained nutrient compositions and percentage by weight is that 95% dextrin, sucrose make particle according to conventional method; The preparation of capsulae vacuus makes according to conventional method; The particle that again embodiment four is made carries out the filling of medicine with mechanical completion method; At last capsule is sealed, promptly make the nutrient composition mass percent and be 5% hard shell capsules finished product.
Embodiment nine [DHA: ALA=1: 2]
In the present embodiment; Take by weighing percentage by weight and be 10% algae oil-bound distemper (DHA content 10%), 3.4% Purple Perilla Seed Oil powder (ALA content 60%), 83.95% peanut oil, 2.0% taurine, 0.05% folic acid, 0.5% zinc gluconate, 0.05% vitamin E, 0.03% vitamin C, 0.02%TBHQ and carry out mixing, filtration, make composition by embodiment one preparation method of composition.
Composition that embodiment nine is made and percentage by weight are 90% the abundant mixing of additive of tablet starch, microcrystalline cellulose, sodium carboxymethylcellulose, sodium carboxymethyl starch, dolomol; Add distilled water and carry out wet granulation; Afterwards particle is carried out drying; Compression molding promptly makes the nutrient composition mass percent and is 10% tablet finished product.
Embodiment ten [DHA: ALA=1: 5]
In the present embodiment; Taking by weighing percentage by weight is 45% fish oil powder (DHA content 10%), 45% Purple Perilla Seed Oil powder (ALA content 50%), 7% peanut oil, 2% lecithin, 0.5% taurine, 0.1% folic acid, 0.2% zinc gluconate, 0.2% vitamin E; Lecithin, vitamin E are dissolved in the peanut oil; Again other nutriments are mixed, stir, make composition.
Take by weighing percentage by weight that embodiment ten makes and be 15% nutrient composition and percentage by weight and be 85% dextrin, sucrose, microcrystalline cellulose, polyvinylpyrrolidone, place in the suitable container to mix, add the softwood that distilled water is processed " hand is pinched agglomerating; pressures promptly diffusing "; Pass through 14～22 eye mesh screens (plate) with fashion of extrusion again, process homogeneous granules, control certain temperature and carry out drying; Water content is controlled in 2%; Must make uniform particles after sieve after the dry grain cooling, promptly make the nutrient composition mass percent and be 15% granule finished product.
Embodiment 11 [DHA: ALA=1: 10]
In the present embodiment; Take by weighing percentage by weight and be 8% fish oil (DHA content 12.5%), 20% linseed oil (ALA content 50%), 69.2% peanut oil, 2% lecithin, 0.5% taurine, 0.15% vitamin C, 0.1% vitamin E, 0.05% beta carotene and carry out preparation of compositions, method is with the preparation method of composition among the embodiment one.
The nutrient composition that makes with embodiment 11 is a content, and the technology according to embodiment one preparation soft capsule makes content nutrient composition mass percent and accounts for 65% soft capsule finished product.
Embodiment 12 [DHA: ALA=1: 5.3]
In the present embodiment, take by weighing 14.3% algae oil (DHA content 35%), 53.3% linseed oil (ALA content 50%), 32.1% peanut oil, 0.3% vitamin E, carry out mixing, filtration, make composition according to preparation of compositions method among the embodiment one.The above-mentioned composition that makes and glue are made content nutrient composition mass percent according to the soft capsule preparation method of embodiment one account for 68% soft capsule finished product.
Below be to effect research of the present invention:
1, experiment material
The sample that algae oil, linseed oil, embodiment one make.Just from 80 of newborn male mouse of kunming, body weight 10～11g.
2, animal experiment
Mouse is divided into four groups at random, every group of each 20 mouse, wherein experimental group is labeled as A, B, C group respectively for three groups, and control group one group echo is the D group, these four groups of mouse is fed raise respectively.
A group: the sample that makes with embodiment one and normal diet stirring and evenly mixing at random hello raise one group of mouse in the experimental group;
B group: the DHA of contained DHA equivalent is converted to a certain amount of algae oil in the sample that will make with embodiment one, feeds at random with the normal diet stirring and evenly mixing and raises arbitrary group of mouse in the experimental group;
C group: the ALA of contained ALA equivalent is converted to a certain amount of linseed oil in the sample that will make with embodiment one, feeds with the normal diet stirring and evenly mixing and raises one group of mouse of residue in the experimental group;
D group: only with the normal diet feeding mice of equivalent as blank.
Mouse was fed after 40 days, and each group mouse is carried out diving tower experiment (experimental result is seen table 1) and water maze laboratory (experimental result is seen table 2) respectively.
Table 1 data show; The diving tower of three groups of experimental mice reduces than control group mice than control group mice prolongation, errors incubation period; (156.1 ± 11.31S) is the longest incubation period with A group mouse diving tower in three groups of experimental group; Be longer than B group and C group mouse diving tower incubation period, especially obviously be longer than with D and organize mouse diving tower incubation period, difference has conspicuousness (P＜0.05).
Table 2 data show; Three groups of experimental mice are walked the labyrinth time than control group mice, and (75.14 ± 7.65S) all shorten; Wherein the A group rat/mouse labyrinth time is 32.32 ± 5.89S; The rat/mouse labyrinth time remarkable shortening is arranged than the D group, difference has conspicuousness (P＜0.05), and errors also significantly reduces (P＜0.05).Above result shows that DHA and ALA have certain promotion to puberty mouse spatial discrimination learning and memory, but A group feed is more remarkable to the facilitation of puberty mouse spatial discrimination learning and memory than the C group feed of the B group feed of equivalent or equivalent.
Table 1 diving tower experimental result
Figure BDA0000076165710000092
Annotate: * and B group and C group be P＜0.05 relatively
Table 2 water maze laboratory result
Figure BDA0000076165710000093
Figure BDA0000076165710000094
Annotate: * and B group and C group be P＜0.05 relatively
Above-described only is preferred implementation of the present invention; Should be pointed out that the those of ordinary skill in the art, under the prerequisite that does not break away from core technology characteristic of the present invention; Can also make some improvement, these improvement and retouching also should be regarded as protection scope of the present invention.

Claims (15)

1. a nutrient composition that promotes nervous system development is characterized in that, comprises nutrient, and described nutrient comprises DHA (DHA) and ALA (alpha-linolenic acid), and the mass ratio of described DHA and ALA is 1: 20～20: 1.
2. the nutrient composition of promotion nervous system development according to claim 1 is characterized in that, the mass ratio of described DHA and ALA is 1: 10～15: 1.
3. the nutrient composition of promotion nervous system development according to claim 1 is characterized in that, the mass ratio of described DHA and ALA is 1: 8～10: 1.
4. the nutrient composition of promotion nervous system development according to claim 1 is characterized in that, the mass ratio of described DHA and ALA is 1: 5～8: 1.
5. according to the nutrient composition of each described promotion nervous system development of claim 1 to 4; It is characterized in that described nutrient also comprises one or more in AA (arachidonic acid), taurine, folic acid, lecithin, reinforcement choline, the zinc gluconate.
6. according to the nutrient composition of each described promotion nervous system development of claim 1 to 4, it is characterized in that described nutrient composition also comprises edible antioxidant.
7. the nutrient composition of promotion nervous system development according to claim 5 is characterized in that, described nutrient composition also comprises edible antioxidant.
8. the nutrient composition of promotion nervous system development according to claim 6; It is characterized in that described edible antioxidant can be one or more in vitamin E, vitamin C, Tea Polyphenols, beta carotene, lycopene, BHA, BHT, TBHQ, n-propyl gallate, the different sodium sorbate.
9. the nutrient composition of promotion nervous system development according to claim 7; It is characterized in that described edible antioxidant can be one or more in vitamin E, vitamin C, Tea Polyphenols, beta carotene, lycopene, BHA, BHT, TBHQ, n-propyl gallate, the different sodium sorbate.
10. according to Claim 8 or the nutrient composition of 9 described promotion nervous system developments, it is characterized in that nutrient composition is made up of 97%～99.98% nutrient and 0.02～3% edible antioxidant by weight percentage.
11. nutrient and healthcare products that promote nervous system development is characterized in that, contain the nutrient composition that promotes nervous system development.
12. the nutrient and healthcare products of promotion nervous system development according to claim 11; It is characterized in that; Finished dosage forms can be soft capsule or microcapsules or capsule or tablet or finish or granule, and wherein nutrient composition accounts for 0.1%～100% of finished product gross mass.
13. the nutrient and healthcare products of promotion nervous system development according to claim 12 is characterized in that, wherein nutrient composition accounts for 5%～95% of finished product gross mass.
14. the nutrient and healthcare products of promotion nervous system development according to claim 13 is characterized in that, wherein nutrient composition accounts for 10%～85% of finished product gross mass.
15. the nutrient and healthcare products of promotion nervous system development according to claim 14 is characterized in that, wherein nutrient composition accounts for 20%～65% of finished product gross mass.
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WO2015009406A1 (en) * 2013-07-16 2015-01-22 Mjn U.S. Holdings Llc Methods for promoting neuronal development and/or health
CN104739860A (en) * 2015-01-27 2015-07-01 上海天龙生物科技有限公司 Alpha-linolenic acid DHA capsule
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CN105962359A (en) * 2016-05-10 2016-09-28 中国农业科学院油料作物研究所 Composition with function of assisting in improving memory
CN106417598A (en) * 2016-09-09 2017-02-22 嘉必优生物技术（武汉）股份有限公司 Preparation method of lycopene-containing microcapsules
CN108402466A (en) * 2017-02-10 2018-08-17 台湾原生药用植物股份有限公司 Vegetarian diet composition containing unsaturated fatty acid
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CN102687859A (en) * 2012-06-09 2012-09-26 东莞市照燕生物科技有限公司 Micronutrient complex health care product
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US9241923B2 (en) 2013-07-16 2016-01-26 Mead Johnson Nutrition Company Methods for promoting neuronal development and/or health
CN104739860A (en) * 2015-01-27 2015-07-01 上海天龙生物科技有限公司 Alpha-linolenic acid DHA capsule
CN105962359A (en) * 2016-05-10 2016-09-28 中国农业科学院油料作物研究所 Composition with function of assisting in improving memory
CN106417598A (en) * 2016-09-09 2017-02-22 嘉必优生物技术（武汉）股份有限公司 Preparation method of lycopene-containing microcapsules
CN108402466A (en) * 2017-02-10 2018-08-17 台湾原生药用植物股份有限公司 Vegetarian diet composition containing unsaturated fatty acid
CN111493315A (en) * 2020-05-26 2020-08-07 广东时代食品与生命健康研究有限公司 Memory-improving antioxidant composition and application thereof

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