CN102309663B - 一种防治龋齿的药剂 - Google Patents
一种防治龋齿的药剂 Download PDFInfo
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Abstract
本发明涉及一种防治龋齿的药剂，它是由下列原料药制成的：金银花、七叶一枝花、甘草、厚朴、猫眼草、山豆根、刺五加、陈皮、当归、生地、白芷、五倍子。本发明所述的药剂以纯中药配制，保持天然药物毒性小、疗效好的特性，疗效明确，可有效地防治龋齿。
Description
技术领域
本发明涉及医药领域，具体地说，涉及一种防治龋齿的药剂。
背景技术
在临床上，正畸患者因矫治时间长，矫治器影响清洁等，菌斑易于堆积，更易导致牙龈炎、牙龈肿胀的发生。因此，为了维持正畸的效果，需要对其进行良好地治疗。
发明内容
本发明的目的是提供一种防治龋齿的药剂。
为了实现本发明的目的，本发明提供一种防治龋齿的药剂，它是由下列原料药按重量份计制成的：
优选地，它是由下列原料药按重量份计制成的：
优选地，本发明所述的药剂为片剂、分散片、汤剂或胶囊剂。
本发明所述的药剂以纯中药配制，保持天然药物毒性小、疗效好的特性，疗效明确，可有效地防治龋齿。
具体实施方式
以下通过具体实施方式的描述对本发明作进一步说明，但这并非是对本发明的限制，本领域技术人员根据本发明的基本思想，可以做出各种修改或改进，但是只要不脱离本发明的基本思想，均在本发明的范围之内。
实施例1本发明汤剂的制备
取金银花100克、七叶一枝花100克、甘草30克、厚朴30克、猫眼草100克、山豆根50克、刺五加50克、陈皮100克、当归50克、生地50克、白芷100克、五倍子100克，置于1500毫升水中，在70℃下加热回流3小时，过滤，得到滤渣和滤液。将所述滤液浓缩至400毫升，灭菌，即得。
实验例
一般资料
参照《龋病学》(岳松龄主编.第1版，成都：四川人民出版社，1983：224-225，280-281)的龋齿的诊断标准来选取牙龈患者50例，其中男性25例，女性25例，年龄最小6岁，最大12岁。就诊前均无服用任何消炎药。
治疗方法
服用实施例1中制备的汤剂，一日三次，每次50毫升。连续使用1周。
疗效评定标准
采用菌斑指数变化作为疗效评定标准的标准。将菌斑指数减少1个以上评定为有效，将菌斑指数保持不变或增加1个以上评定为无效。
菌斑指数(plaque index，PLI)由Silness和Loe在1964年提出，根据压面菌斑的厚度记分而不根据菌斑覆盖面积记分。用于评价口腔卫生状况和衡量牙周病防治效果。
用视诊的结合探针的方法检查，检查是用探针轻划牙面，根据菌斑的量和厚度记分。菌斑指数科检查全口牙面，也可检查选定的几颗牙。每颗牙都检查4个牙面，即近中颊面、正中颊面、远中颊面以及舌面。每颗牙的记分为4个牙面记分之和除以4，个人记分为每颗牙几分之和除以受检牙数。
0＝龈缘区无菌斑；
1＝龈缘区的牙面有薄的菌斑，但视诊不可见，若用探针尖的侧面可挂出菌斑；
2＝在龈缘或邻面可见中等量菌斑；
3＝龈沟内或龈缘区即邻面有大量软够。
根据上述方法测定试验前和一个疗程后的菌斑指数，并根据菌斑指数变化得到下面的试验结果。
治疗结果
对于试验组，有35例患者的菌斑指数减少3，10例患者的菌斑指数减少2，5例患者的菌斑指数减少1。有效率100％。
不良反应
在治疗过程中未发现明显的不良反应。
Claims (1)
1.一种防治龋齿的药剂，其特征在于，它是由下列原料药按重量份计制成的：
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102727803B (zh) * | 2012-07-20 | 2013-08-07 | 王忠亮 | 一种治疗牙周炎的药剂 |
| CN113384620A (zh) * | 2021-07-14 | 2021-09-14 | 青岛市口腔医院 | 一种预防和/或治疗龋齿的中药组合物及其制备方法与应用 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1166968A (zh) * | 1996-09-25 | 1997-12-10 | 河南省宛西制药厂 | 一种保护牙齿的含片及制备方法 |
| CN101862399A (zh) * | 2010-06-28 | 2010-10-20 | 赵丽侠 | 一种防治小儿龋齿的药物及其制备方法 |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1166968A (zh) * | 1996-09-25 | 1997-12-10 | 河南省宛西制药厂 | 一种保护牙齿的含片及制备方法 |
| CN101862399A (zh) * | 2010-06-28 | 2010-10-20 | 赵丽侠 | 一种防治小儿龋齿的药物及其制备方法 |
Non-Patent Citations (4)
| Title |
|---|
| 中药与防龋;刘正;《中华口腔医学杂志》;20060509;第41卷(第05期);282-284 * |
| 中药防龋的研究概况;谢小梅等;《国外医学.中医中药分册》;19951231;第17卷(第04期);15-17 * |
| 刘正.中药与防龋.《中华口腔医学杂志》.2006,第41卷(第05期),282-284. |
| 谢小梅等.中药防龋的研究概况.《国外医学.中医中药分册》.1995,第17卷(第04期),15-17. |
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