CN102292434B - 源自成人肾小球的分离的多潜能间充质干细胞(hGL-MSC)、其制备方法及其在肾脏再生医学中的用途 - Google Patents
源自成人肾小球的分离的多潜能间充质干细胞(hGL-MSC)、其制备方法及其在肾脏再生医学中的用途 Download PDFInfo
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- CN102292434B CN102292434B CN200980154241.9A CN200980154241A CN102292434B CN 102292434 B CN102292434 B CN 102292434B CN 200980154241 A CN200980154241 A CN 200980154241A CN 102292434 B CN102292434 B CN 102292434B
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0684—Cells of the urinary tract or kidneys
- C12N5/0687—Renal stem cells; Renal progenitors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0668—Mesenchymal stem cells from other natural sources
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- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08425708.8 | 2008-11-04 | ||
| EP08425708A EP2186883A1 (en) | 2008-11-04 | 2008-11-04 | An isolated multipotent mesenchymal stem cell from human adult glomeruli (hGL-MSC), a method of preparing thereof and uses thereof in the regenerative medicine of the kidney |
| PCT/EP2009/064468 WO2010052192A1 (en) | 2008-11-04 | 2009-11-02 | An isolated multipotent mesenchymal stem cell from human adult glomeruli (hgl-msc), a method of preparing thereof and uses thereof in the regenerative medicine of the kidney |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102292434A CN102292434A (zh) | 2011-12-21 |
| CN102292434B true CN102292434B (zh) | 2014-03-12 |
Family
ID=40260686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200980154241.9A Active CN102292434B (zh) | 2008-11-04 | 2009-11-02 | 源自成人肾小球的分离的多潜能间充质干细胞(hGL-MSC)、其制备方法及其在肾脏再生医学中的用途 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9499796B2 (https=) |
| EP (2) | EP2186883A1 (https=) |
| JP (1) | JP5795737B2 (https=) |
| CN (1) | CN102292434B (https=) |
| ES (1) | ES2580172T3 (https=) |
| PL (1) | PL2361303T3 (https=) |
| WO (1) | WO2010052192A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2363136A1 (en) | 2010-03-02 | 2011-09-07 | Fresenius Medical Care Deutschland GmbH | Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease |
| TWI762890B (zh) | 2010-05-12 | 2022-05-01 | 開曼群島商英瑞金公司 | 生物活性腎細胞 |
| WO2012030968A1 (en) * | 2010-08-31 | 2012-03-08 | Renovocyte, LLC | Systemic, allogenic stem cell therapies for treatment of diseases in animals |
| CN103261407B (zh) * | 2010-12-22 | 2016-03-02 | 杜兰教育基金委员会 | 用于识别和培养具有高度增殖潜能的多能间充质干细胞的方法 |
| AU2012279995C1 (en) | 2011-07-06 | 2019-10-24 | Cell Therapy Limited | Progenitor cells of mesodermal lineage |
| EP2760995B1 (en) * | 2011-09-30 | 2019-08-07 | The University Of Miami | Renal stem cells isolated from kidney |
| RU2702721C2 (ru) | 2012-10-24 | 2019-10-09 | инРиджен | Популяции клеток почек и их применение |
| WO2014113704A2 (en) * | 2013-01-18 | 2014-07-24 | Escape Therapeutics, Inc. | Enhanced differentiation of mesenchymal stem cells |
| CN104977414B (zh) * | 2014-04-09 | 2016-09-28 | 上海交通大学医学院 | 鉴定骨髓中是否存在保护白血病干细胞微环境的试剂盒及其应用 |
| CN106715683A (zh) * | 2014-08-21 | 2017-05-24 | 味之素株式会社 | 间充质干细胞用培养基 |
| TWI689589B (zh) * | 2016-08-31 | 2020-04-01 | 宣捷細胞生物製藥股份有限公司 | 區別間質幹細胞的方法及測定間質幹細胞的純度的方法 |
| CN106265745A (zh) * | 2016-09-30 | 2017-01-04 | 广州赛莱拉干细胞科技股份有限公司 | 一种干细胞制剂及其在制备治疗慢性肾炎的药物中的应用 |
| JP7072777B2 (ja) * | 2018-07-03 | 2022-05-23 | 株式会社生命科学インスティテュート | 慢性腎障害治療のための多能性幹細胞 |
| EP4146787A4 (en) | 2020-05-08 | 2024-06-26 | Gallant Pet, Inc. | Uterine-derived regenerative cell compositions and uses thereof |
| CN117871216B (zh) * | 2024-03-12 | 2024-06-04 | 中日友好医院(中日友好临床医学研究所) | 一种石蜡标本中肾小球裂隙膜的三维可视化方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007125088A3 (en) * | 2006-04-28 | 2008-01-10 | Azienda Ospedaliero Universita | Kidney-derived stem cell population, identification and therapeutic use |
| WO2008045498A1 (en) * | 2006-10-12 | 2008-04-17 | Ethicon, Inc. | Kidney-derived cells and methods of use in tissue repair and regeneration |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4085410B2 (ja) * | 2003-03-14 | 2008-05-14 | 株式会社 バイオリンクインク | 腎臓幹細胞/前駆細胞、腎臓幹細胞/前駆細胞の分離方法、及び腎疾患の治療方法 |
-
2008
- 2008-11-04 EP EP08425708A patent/EP2186883A1/en not_active Withdrawn
-
2009
- 2009-11-02 US US13/127,589 patent/US9499796B2/en active Active
- 2009-11-02 WO PCT/EP2009/064468 patent/WO2010052192A1/en not_active Ceased
- 2009-11-02 CN CN200980154241.9A patent/CN102292434B/zh active Active
- 2009-11-02 PL PL09744160.4T patent/PL2361303T3/pl unknown
- 2009-11-02 EP EP09744160.4A patent/EP2361303B8/en active Active
- 2009-11-02 JP JP2011535090A patent/JP5795737B2/ja active Active
- 2009-11-02 ES ES09744160.4T patent/ES2580172T3/es active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007125088A3 (en) * | 2006-04-28 | 2008-01-10 | Azienda Ospedaliero Universita | Kidney-derived stem cell population, identification and therapeutic use |
| WO2008045498A1 (en) * | 2006-10-12 | 2008-04-17 | Ethicon, Inc. | Kidney-derived cells and methods of use in tissue repair and regeneration |
Non-Patent Citations (4)
| Title |
|---|
| Co-expression of two perivascular cell markers isolates mesenchymal stem-like cells from human endometrium;KE Schwab, 等;《Human Reproduction》;20071130;第22卷(第11期);第2903-2911页 * |
| Isolation and Characterization of Mulipotent Progenitor Cells from the Bowman"s Capsule of Adult Human Kidneys;Costanza Sagrinati, 等;《Journal of the American Society of Nephrology》;20060901;第17卷(第9期);第2443-2456页 * |
| Isolation and Characterization of Resident Mesenchymal Stem Cells in Human Glomeruli;Stefania Bruno, 等;《Stem Cells and Development》;20090202;第18卷(第6期);第687-880页 * |
| Mesenchymal stem cells reside in virtually all post-natal organs and tissues;Londolfo da Silva Meirelles, 等;《Cell Science》;20060601;第119卷(第11期);第2204-2213页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2012507304A (ja) | 2012-03-29 |
| US9499796B2 (en) | 2016-11-22 |
| WO2010052192A1 (en) | 2010-05-14 |
| US20110256111A1 (en) | 2011-10-20 |
| JP5795737B2 (ja) | 2015-10-14 |
| EP2361303B8 (en) | 2016-08-10 |
| CN102292434A (zh) | 2011-12-21 |
| EP2361303B1 (en) | 2016-04-06 |
| PL2361303T3 (pl) | 2016-10-31 |
| EP2361303A1 (en) | 2011-08-31 |
| EP2186883A1 (en) | 2010-05-19 |
| ES2580172T3 (es) | 2016-08-19 |
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