CN102284094B - Non-drug therapy system for septicopyemia caused by drug-resistance bacteria - Google Patents
Non-drug therapy system for septicopyemia caused by drug-resistance bacteria Download PDFInfo
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- CN102284094B CN102284094B CN201110197184.1A CN201110197184A CN102284094B CN 102284094 B CN102284094 B CN 102284094B CN 201110197184 A CN201110197184 A CN 201110197184A CN 102284094 B CN102284094 B CN 102284094B
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Abstract
The invention relates to a non-drug therapy system for septicopyemia caused by drug-resistance bacteria, which is structurally characterized by comprising a blood plasma collector, a disposable mechanically collected plasma separating and pathogen inactivating multipurpose treater and a high hydrostatic pressure (HHP) plasma pathogen inactivating instrument, wherein the disposable mechanically collected plasma separating and pathogen inactivating multipurpose treater comprises a blood collector, a pipeline, a plasma separating cup, a tubular plasma collecting and ultrahigh pressure inactivating processing bag, a puncturing cap, a hemostatic clamp, a blood filter, a pressure monitor, a saline water back transfusion needle and a protective cap thereof and an anticoagulant and a protective cap thereof. In the non-drug therapy system for the septicopyemia caused by the drug-resistance bacteria, the blood plasma collector and the HHP plasma pathogen inactivating instrument in the prior art are connected and combined by using a treater designed by an inventer and installing an operational program to realize plasma pathogen inactivating by system integration, and discontinuous closed transfusion treatment is carried out on plasma of which the pathogen is inactivated at an ultrahigh pressure to achieve the goal of anti-pathogen therapy. The on-drug therapy system for the septicopyemia caused by the drug-resistance bacteria has a wide pathogen inactivating spectrum and low cost and is safe and effective.
Description
Technical field
This is non-drug therapy system for septicopyemia caused by drug-resistance bacteria for the present invention, belongs to infectious disease treatment, safe transfusion, blood products field.
Background technology
The microorganism that corresponding antibiotic is produced to tolerance occurring after long-term antibiotic is selected, general designation fastbacteria.The drug resistance of so-called antibacterial, refer to antibacterial repeatedly with medicament contact after, the sensitivity of medicine is reduced even to disappear, cause medicine to reduce the curative effect of fastbacteria even invalid.The forties, penicillin is applied to clinical antibiotic as the first, has successfully solved golden Portugal bacterium clinically and has infected this difficult problem.The Macrolide coming out subsequently, aminoaglycon antibiotics makes again pneumonia, phthisical mortality rate reduce by 80%, and once someone asserted at that time: the mankind defeat the epoch of antibacterial to arrive.But true and fine unlike people's imagination, many antibiotic have occurred that in application drug effect in various degree lowers for many years afterwards, natural penicillin is almost losing medical value aspect control golden Portugal bacterium infection.Physician surprisingly finds after this phenomenon of research, after contacting repeatedly with antibiotic, antibacterial a whole set of effective resistance mechanism of having evolved out, fastbacteria this hiding enemy is powerful gradually in the dark.
In China, the situation of abuse of antibiotics is also very general, and according to investigations, China outpatient service flu patient approximately has 75% application antibiotic, and the situation of surgical operation perioperative systematic antibiotics is up to 95%.In inpatient, antibiotic utility ratio is 79%, and this numeral is far away higher than the 22%He various countries average level 30% of Britain.Meanwhile, due to doctor, abuse the broad-spectrum antiseptic class medicines such as ampicillin, cause dysbacteriosis in human body and bring out the situation of superinfection of common occurrence especially.
Even to this day, the fastbacteria problem of China has become very outstanding, the microbial nosocomial infection number of drug resistance, and 30% left and right that has accounted for HOI patient total number of persons, unfortunately, the invention of new antibiotic cannot be caught up with the step of resistance.Mostly serious symptom pyaemia septica is growth and breeding in these type of drug resistance pathogenic bacterium or conditioned pathogen intrusion blood circulation, produce toxin and the caused acute systemic infection of other metabolites, take clinically shiver with cold, high heat, erythra, arthralgia and hepatosplenomegaly is feature, and part can have septic shock and migrate sexually transmitted disease (STD) kitchen range.The appearance of fastbacteria has increased the difficulty that infectious disease is cured, and forces the mankind to find the method that new combating microorganisms infects.
Summary of the invention
The invention provides non-drug therapy system for septicopyemia caused by drug-resistance bacteria, adopt this non-drug therapy system for septicopyemia caused by drug-resistance bacteria to process, the pathogenic bacteria of drug-resistant existing directly can be killed in blood plasma, reach the object of disease-resistant former treatment.And with low cost, that any chemicals is not added in the deactivation of HHP cause of disease is safe and effective, cause of disease deactivation spectrum is wide, with low cost, safe and effective, simple in structure, easy to operate, good with existing equipment compatibility, suitable popularization.
The technical solution used in the present invention is: non-drug therapy system for septicopyemia caused by drug-resistance bacteria, non-drug therapy system for septicopyemia caused by drug-resistance bacteria, its formation comprises blood plasma collecting machine, disposable machine-collected plasma bacterial isolate deactivation Multi-purpose processor, HHP blood plasma cause of disease deactivation instrument, wherein disposable machine-collected plasma bacterial isolate deactivation Multi-purpose processor comprises hemostix, pipeline, separating plasma cup, tubular plasma collection supertension inactivation treatment bag, lengthen blood plasma pipeline, puncture cap, flow-stopping clip, blood filter, pressure monitor, saline feeds back pin and helmet, anticoagulant and helmet, it is characterized in that: hemostix arranges connecting tee after flow-stopping clip, feed back pin and helmet and anticoagulant and helmet with saline again the pipeline of flow-stopping clip after in parallel is set, blood filter connects, blood filter Bonding pressure monitor, and connect with separating plasma cup by pipeline, separating plasma cup is by lengthening after blood plasma pipeline connecting tee and tubular plasma collection supertension inactivation treatment bag, on tubular plasma collection supertension inactivation treatment bag, puncture cap is set.
The application of non-drug therapy system for septicopyemia caused by drug-resistance bacteria of the present invention, above-mentioned disposable machine-collected plasma bacterial isolate deactivation Multi-purpose processor blood is installed in blood plasma collecting machine, blood, by hemostix flow ipe from human body collection, injects a certain proportion of anticoagulant by anticoagulant and helmet, now saline feeds back pin and helmet closedown of pipeline, the blood that injects certain anticoagulant flows into separating plasma cup by blood filter, the blood plasma flowing out by separating plasma cup enters tubular plasma collection supertension inactivation treatment bag, capacity can be at 200ml-800ml, blood flows into after tubular plasma collection supertension inactivation treatment bag by pipeline, after reaching quantitative blood plasma, cutting out pipeline is carried out and is fused, tubular plasma collection supertension inactivation treatment bag is put into HHP blood plasma cause of disease deactivation instrument and carry out cause of disease deactivation, blood plasma in tubular plasma collection supertension inactivation treatment bag after deactivation can feed back pin by saline and feed back human body, reach therapeutic purposes.
Tubular plasma collection supertension inactivation treatment bag is high pressure inactivating device (blood plasma pressurized under 5 ℃～15 ℃, 250～350MPa condition being processed 5～10 minutes to pressurization pressure release circulation 1-3 time), feeds back pin feed back to human body after deactivation by saline.
The present invention has obtained following beneficial effect: adopt non-drug therapy system for septicopyemia caused by drug-resistance bacteria, with low cost, do not add any chemicals, it is wide, with low cost, safe and effective that pathogen is killed spectrum, simple in structure, easy to operate, good with existing equipment compatibility, suitable popularization.In addition, the blood plasma collecting machine of prior art and HHP blood plasma cause of disease deactivation instrument can be realized to the deactivation of supertension cause of disease with processor and the combination of fitting operation program chains of inventor's design, the pathogenic bacteria of drug-resistant existing in blood plasma is directly effectively killed.After deactivation, discontinuous blood plasma feeds back and processes, and reaches the object for the treatment of.
Accompanying drawing explanation
Fig. 1 is blood separation device structure schematic diagram, wherein.
1-hemostix, 2-pipeline, 3-separating plasma cup, 4-tubular plasma collection supertension inactivation treatment bag, 5-lengthens blood plasma pipeline, 6-flow-stopping clip I, 7-flow-stopping clip II, the 8-cap that punctures, 9-flow-stopping clip III, 10-blood filter, 11-pressure monitor, 12-saline feeds back pin and helmet, 13-anticoagulant and helmet.
The specific embodiment
Below in conjunction with accompanying drawing, the present invention is done to a detailed description:
The technical solution used in the present invention is: non-drug therapy system for septicopyemia caused by drug-resistance bacteria, its formation comprises blood plasma collecting machine, disposable machine-collected plasma bacterial isolate deactivation Multi-purpose processor, HHP blood plasma cause of disease deactivation instrument, wherein disposable machine-collected plasma bacterial isolate deactivation Multi-purpose processor comprises hemostix, pipeline, separating plasma cup, tubular plasma collection supertension inactivation treatment bag, lengthen blood plasma pipeline, puncture cap, flow-stopping clip, blood filter, pressure monitor, saline feeds back pin and helmet, anticoagulant and helmet, it is characterized in that: hemostix arranges connecting tee after flow-stopping clip, feed back pin and helmet and anticoagulant and helmet with saline again the pipeline of flow-stopping clip after in parallel is set, blood filter connects, blood filter Bonding pressure monitor, and connect with separating plasma cup by pipeline, separating plasma cup is by lengthening after blood plasma pipeline connecting tee and tubular plasma collection supertension inactivation treatment bag, on tubular plasma collection supertension inactivation treatment bag, puncture cap is set.
The application of non-drug therapy system for septicopyemia caused by drug-resistance bacteria of the present invention, that above-mentioned disposable machine-collected plasma bacterial isolate deactivation Multi-purpose processor blood is installed in blood plasma collecting machine, blood, by hemostix flow ipe from human body collection, injects a certain proportion of anticoagulant by anticoagulant and helmet, now saline feeds back pin and helmet closedown of pipeline, the blood that injects certain anticoagulant flows into separating plasma cup by blood filter, the blood plasma flowing out by separating plasma cup enters tubular plasma collection supertension inactivation treatment bag, capacity can be at 200ml-800ml, blood flows into after tubular plasma collection supertension inactivation treatment bag by pipeline, after reaching quantitative blood plasma, cutting out pipeline is carried out and is fused, tubular plasma collection supertension inactivation treatment bag is put into HHP blood plasma cause of disease deactivation instrument and carry out cause of disease deactivation, blood plasma in tubular plasma collection supertension inactivation treatment bag after deactivation can feed back pin by saline and feed back human body, reach therapeutic purposes.
Tubular plasma collection supertension inactivation treatment bag is high pressure inactivating device (blood plasma pressurized under 5 ℃～15 ℃, 250～350MPa condition being processed 5～10 minutes to pressurization pressure release circulation 1-3 time), feeds back pin feed back to human body after deactivation by saline.
Performance test: by applying under 5 ℃～15 ℃, 250～350MPa condition, the method for cycle-index (1-2 time), evidence, can kill the pathogen such as Resistant Staphylococcus epidermidis, and the normal composition of blood plasma has no significant effect.
Claims (1)
1. non-drug therapy system for septicopyemia caused by drug-resistance bacteria, its formation comprises: blood plasma collecting machine, disposable machine-collected plasma bacterial isolate deactivation Multi-purpose processor, HHP blood plasma cause of disease deactivation instrument, wherein disposable machine-collected plasma bacterial isolate deactivation Multi-purpose processor comprises: hemostix, pipeline, separating plasma cup, tubular plasma collection supertension inactivation treatment bag, lengthen blood plasma pipeline, puncture cap, flow-stopping clip, blood filter, pressure monitor, saline feeds back pin and helmet, anticoagulant and helmet, it is characterized in that: hemostix arranges connecting tee after flow-stopping clip, feed back pin and helmet and anticoagulant and helmet with saline again the pipeline of flow-stopping clip after in parallel is set, blood filter connects, blood filter Bonding pressure monitor, and be connected with separating plasma cup by pipeline, separating plasma cup is connected with tubular plasma collection supertension inactivation treatment bag after lengthening blood plasma pipeline connecting tee, on tubular plasma collection supertension inactivation treatment bag, puncture cap is set, puncture cap is used as feeding back puncture.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201110197184.1A CN102284094B (en) | 2011-07-14 | 2011-07-14 | Non-drug therapy system for septicopyemia caused by drug-resistance bacteria |
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| CN201110197184.1A CN102284094B (en) | 2011-07-14 | 2011-07-14 | Non-drug therapy system for septicopyemia caused by drug-resistance bacteria |
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| CN102284094B true CN102284094B (en) | 2014-03-12 |
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| CN104174042A (en) * | 2014-08-29 | 2014-12-03 | 郑州飞龙医疗设备有限公司 | Ultrahigh-pressure inactivating method for pathogens in biological products and applications thereof |
| CN105854039B (en) * | 2016-05-21 | 2019-01-25 | 郑州飞龙医疗设备有限公司 | To the super-pressure ablation method and equipment of pathogen in liquid bio product |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2393550Y (en) * | 1999-09-09 | 2000-08-30 | 浙江博朗生物工程有限公司 | Automatic blood separator |
| CN2443725Y (en) * | 2000-11-06 | 2001-08-22 | 张明礼 | Blood treating curing machine |
| CN1404883A (en) * | 2001-08-10 | 2003-03-26 | 可乐丽股份有限公司 | Blood treatment apparatus |
| CN101534877A (en) * | 2006-11-08 | 2009-09-16 | 美国血液技术公司 | Adaptable perioperative cell-salvage system and methods and disposable units for same |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2393550Y (en) * | 1999-09-09 | 2000-08-30 | 浙江博朗生物工程有限公司 | Automatic blood separator |
| CN2443725Y (en) * | 2000-11-06 | 2001-08-22 | 张明礼 | Blood treating curing machine |
| CN1404883A (en) * | 2001-08-10 | 2003-03-26 | 可乐丽股份有限公司 | Blood treatment apparatus |
| CN101534877A (en) * | 2006-11-08 | 2009-09-16 | 美国血液技术公司 | Adaptable perioperative cell-salvage system and methods and disposable units for same |
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